YU45204B - Process for making derivatives of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyle-quinoline-3-carboxilic acid - Google Patents

Process for making derivatives of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyle-quinoline-3-carboxilic acid

Info

Publication number
YU45204B
YU45204B YU1603/84A YU160384A YU45204B YU 45204 B YU45204 B YU 45204B YU 1603/84 A YU1603/84 A YU 1603/84A YU 160384 A YU160384 A YU 160384A YU 45204 B YU45204 B YU 45204B
Authority
YU
Yugoslavia
Prior art keywords
piperazinyle
quinoline
dihydro
oxo
fluoro
Prior art date
Application number
YU1603/84A
Other languages
English (en)
Other versions
YU160384A (en
Inventor
Y Ioh
H Kato
N Ogawa
E Koshinaka
T Suzuki
N Yagi
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP17127183A external-priority patent/JPS6064979A/ja
Priority claimed from JP4566484A external-priority patent/JPS60190777A/ja
Priority claimed from JP12378084A external-priority patent/JPS615075A/ja
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Priority to SI8411603A priority Critical patent/SI8411603A8/sl
Publication of YU160384A publication Critical patent/YU160384A/xx
Publication of YU45204B publication Critical patent/YU45204B/xx
Priority to HRP-1603/84A priority patent/HRP930651B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU1603/84A 1983-09-19 1984-09-18 Process for making derivatives of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyle-quinoline-3-carboxilic acid YU45204B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI8411603A SI8411603A8 (sl) 1983-09-19 1984-09-18 Postopek za pripravo derivatov 6-fluoro-1.4-dihidro-4-okso-7-substituiranih piperazinil - kinolin-3-karboksilnih kislin
HRP-1603/84A HRP930651B1 (en) 1983-09-19 1993-04-01 Process for the preparation of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP17127183A JPS6064979A (ja) 1983-09-19 1983-09-19 ７−ピペラジン置換−６−フルオロ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
JP4566484A JPS60190777A (ja) 1984-03-12 1984-03-12 光学活性な６，８−ジフルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体
JP12378084A JPS615075A (ja) 1984-06-18 1984-06-18 ６−フルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体

Publications (2)

Publication Number Publication Date
YU160384A YU160384A (en) 1987-02-28
YU45204B true YU45204B (en) 1992-05-28

Family

ID=27292329

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1603/84A YU45204B (en) 1983-09-19 1984-09-18 Process for making derivatives of 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyle-quinoline-3-carboxilic acid

Country Status (13)

Country Link
US (1) US4528287A (hu)
EP (1) EP0140116B1 (hu)
KR (1) KR870001016B1 (hu)
AU (1) AU553415B2 (hu)
CA (1) CA1238638A (hu)
DE (1) DE3433924A1 (hu)
DK (1) DK157997C (hu)
ES (2) ES8604565A1 (hu)
FI (1) FI80033C (hu)
FR (1) FR2555584B1 (hu)
HK (1) HK62191A (hu)
HU (1) HU193226B (hu)
YU (1) YU45204B (hu)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
EP0191185B1 (en) * 1984-12-14 1990-03-07 Daiichi Seiyaku Co., Ltd. Quinoline-carboxylic acid derivatives
US4755513A (en) * 1985-01-30 1988-07-05 Otsuka Pharmaceutical Company, Limited Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
NZ217650A (en) * 1985-09-24 1989-09-27 Hoffmann La Roche Quinoline derivatives and pharmaceutical compositions
HU196782B (en) * 1985-12-09 1989-01-30 Chinoin Gyogyszer Es Vegyeszet Process for production of quinoline carbonic acid
CA1306750C (en) * 1985-12-09 1992-08-25 Istvan Hermecz Process for the preparation of quinoline carboxylic acide
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
JPH0696533B2 (ja) * 1987-01-14 1994-11-30 北陸製薬株式会社 キノロンカルボン酸の水性組成物
EP0394326B1 (en) * 1987-12-10 1996-07-31 La Jolla Cancer Research Foundation Methods for the production of conformationally stabilized cell adhesion peptides
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
IL90635A0 (en) * 1988-07-15 1990-01-18 Abbott Lab Process for the preparation of quinoline antibacterial compounds
FR2655545B1 (fr) * 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
AU3147493A (en) * 1991-11-27 1993-06-28 Sepracor, Inc. Methods and compositions for treating infection using optically pure (s)-lomefloxacin
US5476854A (en) * 1991-11-27 1995-12-19 Sepracor Inc. Methods and compositions for treating bacterial infection using optically pure (R)-lomefloxacin
US6075024A (en) 1991-11-27 2000-06-13 Sepracor Inc. Methods for treating infection using optically pure (S)-lomefloxacin
DK0661974T3 (da) * 1991-11-27 2000-10-16 Sepracor Inc Fremgangsmåde og præparater til behandling af infektion under anvendelse af optisk ren (R)-lomefloxacin
US5430152A (en) * 1993-02-16 1995-07-04 Hoechst Celanese Corporation Method for preparing quinoline carboxylic acids and derivatives thereof
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
US5668134A (en) * 1994-01-28 1997-09-16 G. D. Searle & Co. Method for preventing or reducing photosensitivity and/or phototoxicity reactions to medications
US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids
JP5138128B2 (ja) * 1998-08-21 2013-02-06 千寿製薬株式会社 水性液剤
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SE9904108D0 (sv) * 1999-11-15 1999-11-15 New Pharma Research Ab Nya föreningar
TW584632B (en) 2000-01-12 2004-04-21 Pharmaceutical Ind Tech & Dev 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions
DE102005006827A1 (de) * 2004-11-04 2006-05-24 Huhtamaki Ronsberg, Zweigniederlassung Der Huhtamaki Deutschland Gmbh & Co. Kg Verfahren zur Herstellung eines flaschen- oder schlauchartigen Behälters, insbesondere Schlauchbeutels, mit einem eingesiegelten Boden sowie entsprechend hergestellter Schlauchbeutel
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
FR2916446B1 (fr) 2007-05-24 2009-08-21 Biocodex Sa Nouveau procede de synthese de fluoroquinolones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
US4292317A (en) * 1977-09-20 1981-09-29 Laboratorie Roger Bellon 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS5762259A (en) * 1980-09-05 1982-04-15 Kyorin Pharmaceut Co Ltd Preparation of substituted quinolinecarboxylic acid derivative
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative
JPS5910580A (ja) * 1982-07-09 1984-01-20 Hokuriku Seiyaku Co Ltd ７−フエニル置換ピペラジノ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
JPS5929685A (ja) * 1982-08-11 1984-02-16 Hokuriku Seiyaku Co Ltd ７−置換フエニルピペラジノ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents

Also Published As

Publication number Publication date
DE3433924C2 (hu) 1988-07-28
KR870001016B1 (ko) 1987-05-23
DE3433924A1 (de) 1985-04-04
HK62191A (en) 1991-08-16
FI843620A0 (fi) 1984-09-17
DK157997C (da) 1990-08-06
FI843620L (fi) 1985-03-20
HUT35666A (en) 1985-07-29
ES8604565A1 (es) 1986-02-01
DK445084D0 (da) 1984-09-18
HU193226B (en) 1987-08-28
AU553415B2 (en) 1986-07-17
ES536004A0 (es) 1986-02-01
YU160384A (en) 1987-02-28
EP0140116A1 (en) 1985-05-08
KR850002481A (ko) 1985-05-13
FR2555584A1 (fr) 1985-05-31
ES8609303A1 (es) 1986-07-16
FR2555584B1 (fr) 1987-10-23
ES545756A0 (es) 1986-07-16
CA1238638A (en) 1988-06-28
AU3298484A (en) 1985-03-28
DK157997B (da) 1990-03-12
FI80033C (fi) 1990-04-10
US4528287A (en) 1985-07-09
DK445084A (da) 1985-03-20
FI80033B (fi) 1989-12-29
EP0140116B1 (en) 1988-05-25

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