FI843620L - 6-fluor-1,4-dihydro-4-oxo-7- substituerad piperazinyl-kinolin-3-karboxylsyraderivat och foerfarande foer dess framstaellning. - Google Patents

6-fluor-1,4-dihydro-4-oxo-7- substituerad piperazinyl-kinolin-3-karboxylsyraderivat och foerfarande foer dess framstaellning.

Info

Publication number
FI843620L
FI843620L FI843620A FI843620A FI843620L FI 843620 L FI843620 L FI 843620L FI 843620 A FI843620 A FI 843620A FI 843620 A FI843620 A FI 843620A FI 843620 L FI843620 L FI 843620L
Authority
FI
Finland
Prior art keywords
carboxylsyraderives
quinolin
piperazinyl
substitutes
dihydro
Prior art date
Application number
FI843620A
Other languages
English (en)
Other versions
FI843620A0 (fi
FI80033C (fi
FI80033B (fi
Inventor
Yasuo Itoh
Hideo Kato
Nobuo Ogawa
Eiichi Koshinaka
Tomio Suzuki
Noriyuki Yagi
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP17127183A external-priority patent/JPS6064979A/ja
Priority claimed from JP4566484A external-priority patent/JPS60190777A/ja
Priority claimed from JP12378084A external-priority patent/JPS615075A/ja
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Publication of FI843620A0 publication Critical patent/FI843620A0/fi
Publication of FI843620L publication Critical patent/FI843620L/fi
Application granted granted Critical
Publication of FI80033B publication Critical patent/FI80033B/fi
Publication of FI80033C publication Critical patent/FI80033C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
FI843620A 1983-09-19 1984-09-17 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 6-fluor-1,4-dihydro-4-oxo-7-substituerat piperazinylkinolin-3-karboxylderivat. foer dess framstaellning. FI80033C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP17127183 1983-09-19
JP17127183A JPS6064979A (ja) 1983-09-19 1983-09-19 ７−ピペラジン置換−６−フルオロ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
JP4566484 1984-03-12
JP4566484A JPS60190777A (ja) 1984-03-12 1984-03-12 光学活性な６，８−ジフルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体
JP12378084A JPS615075A (ja) 1984-06-18 1984-06-18 ６−フルオロ−１，４−ジヒドロ−４−オキソ−７−置換ピペラジニルキノリン−３−カルボン酸誘導体
JP12378084 1984-06-18

Publications (4)

Publication Number Publication Date
FI843620A0 FI843620A0 (fi) 1984-09-17
FI843620L true FI843620L (fi) 1985-03-20
FI80033B FI80033B (fi) 1989-12-29
FI80033C FI80033C (fi) 1990-04-10

Family

ID=27292329

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843620A FI80033C (fi) 1983-09-19 1984-09-17 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 6-fluor-1,4-dihydro-4-oxo-7-substituerat piperazinylkinolin-3-karboxylderivat. foer dess framstaellning.

Country Status (13)

Country Link
US (1) US4528287A (fi)
EP (1) EP0140116B1 (fi)
KR (1) KR870001016B1 (fi)
AU (1) AU553415B2 (fi)
CA (1) CA1238638A (fi)
DE (1) DE3433924A1 (fi)
DK (1) DK157997C (fi)
ES (2) ES8604565A1 (fi)
FI (1) FI80033C (fi)
FR (1) FR2555584B1 (fi)
HK (1) HK62191A (fi)
HU (1) HU193226B (fi)
YU (1) YU45204B (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
EP0191185B1 (en) * 1984-12-14 1990-03-07 Daiichi Seiyaku Co., Ltd. Quinoline-carboxylic acid derivatives
US4755513A (en) * 1985-01-30 1988-07-05 Otsuka Pharmaceutical Company, Limited Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
ATE72668T1 (de) * 1985-09-24 1992-03-15 Hoffmann La Roche Chinolinderivate.
HU196782B (en) * 1985-12-09 1989-01-30 Chinoin Gyogyszer Es Vegyeszet Process for production of quinoline carbonic acid
CA1306750C (en) * 1985-12-09 1992-08-25 Istvan Hermecz Process for the preparation of quinoline carboxylic acide
JPS62205060A (ja) * 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
JPH0696533B2 (ja) * 1987-01-14 1994-11-30 北陸製薬株式会社 キノロンカルボン酸の水性組成物
WO1989005150A1 (en) * 1987-12-10 1989-06-15 La Jolla Cancer Research Foundation Conformationally stabilized cell adhesion peptides
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
IL90635A0 (en) * 1988-07-15 1990-01-18 Abbott Lab Process for the preparation of quinoline antibacterial compounds
FR2655545B1 (fr) * 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
US5476854A (en) * 1991-11-27 1995-12-19 Sepracor Inc. Methods and compositions for treating bacterial infection using optically pure (R)-lomefloxacin
AU3147493A (en) * 1991-11-27 1993-06-28 Sepracor, Inc. Methods and compositions for treating infection using optically pure (s)-lomefloxacin
US6075024A (en) * 1991-11-27 2000-06-13 Sepracor Inc. Methods for treating infection using optically pure (S)-lomefloxacin
DE69231423T2 (de) * 1991-11-27 2001-01-04 Sepracor Inc Verfahren und Zusammensetzung zur Behandlung von Infektionen unter Verwendung von optisch reinem (R) - Lomefloxacin
US5430152A (en) * 1993-02-16 1995-07-04 Hoechst Celanese Corporation Method for preparing quinoline carboxylic acids and derivatives thereof
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
US5668134A (en) * 1994-01-28 1997-09-16 G. D. Searle & Co. Method for preventing or reducing photosensitivity and/or phototoxicity reactions to medications
US6114531A (en) * 1998-07-28 2000-09-05 Pfizer Inc. Process for preparing quinolone and naphthyridone carboxylic acids
ES2264266T3 (es) * 1998-08-21 2006-12-16 Senju Pharmaceutical Co., Ltd. Preparaciones liquidas acuosas.
FR2797874B1 (fr) * 1999-08-27 2002-03-29 Adir Nouveaux derives de la pyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SE9904108D0 (sv) * 1999-11-15 1999-11-15 New Pharma Research Ab Nya föreningar
TW584632B (en) 2000-01-12 2004-04-21 Pharmaceutical Ind Tech & Dev 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions
DE102005006827A1 (de) * 2004-11-04 2006-05-24 Huhtamaki Ronsberg, Zweigniederlassung Der Huhtamaki Deutschland Gmbh & Co. Kg Verfahren zur Herstellung eines flaschen- oder schlauchartigen Behälters, insbesondere Schlauchbeutels, mit einem eingesiegelten Boden sowie entsprechend hergestellter Schlauchbeutel
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
FR2916446B1 (fr) 2007-05-24 2009-08-21 Biocodex Sa Nouveau procede de synthese de fluoroquinolones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53141286A (en) * 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
CA1175836A (en) * 1977-09-20 1984-10-09 Marcel Pesson Production of 1,4-dihydroquinoline-3-carboxylic acid derivatives
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
DE3033157A1 (de) * 1980-09-03 1982-04-01 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
JPS5762259A (en) * 1980-09-05 1982-04-15 Kyorin Pharmaceut Co Ltd Preparation of substituted quinolinecarboxylic acid derivative
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative
JPS5910580A (ja) * 1982-07-09 1984-01-20 Hokuriku Seiyaku Co Ltd ７−フエニル置換ピペラジノ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
JPS5929685A (ja) * 1982-08-11 1984-02-16 Hokuriku Seiyaku Co Ltd ７−置換フエニルピペラジノ−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体
IE55898B1 (en) * 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents

Also Published As

Publication number Publication date
DE3433924A1 (de) 1985-04-04
DK445084A (da) 1985-03-20
FR2555584B1 (fr) 1987-10-23
DE3433924C2 (fi) 1988-07-28
DK445084D0 (da) 1984-09-18
YU45204B (en) 1992-05-28
ES8604565A1 (es) 1986-02-01
HK62191A (en) 1991-08-16
ES536004A0 (es) 1986-02-01
CA1238638A (en) 1988-06-28
KR850002481A (ko) 1985-05-13
ES545756A0 (es) 1986-07-16
DK157997B (da) 1990-03-12
HUT35666A (en) 1985-07-29
DK157997C (da) 1990-08-06
AU3298484A (en) 1985-03-28
FI843620A0 (fi) 1984-09-17
YU160384A (en) 1987-02-28
HU193226B (en) 1987-08-28
FI80033C (fi) 1990-04-10
FR2555584A1 (fr) 1985-05-31
EP0140116B1 (en) 1988-05-25
FI80033B (fi) 1989-12-29
EP0140116A1 (en) 1985-05-08
KR870001016B1 (ko) 1987-05-23
AU553415B2 (en) 1986-07-17
ES8609303A1 (es) 1986-07-16
US4528287A (en) 1985-07-09

Similar Documents

Publication Publication Date Title
FI843620L (fi) 6-fluor-1,4-dihydro-4-oxo-7- substituerad piperazinyl-kinolin-3-karboxylsyraderivat och foerfarande foer dess framstaellning.
FI843594A0 (fi) Trihalogenmetylgrupper innehaollande karbonylmetylenheterocykler, foerfarande foer deras framstaellning och ljuskaenslig blandning vilken innehaoller dessa foereningar.
FI845038A0 (fi) Vattenloeslig, aminerad -1,3-bunden d-glukan och komposition innehaollande densamma.
FI840576A (fi) Sammansatt elektrodstruktur och foerfarande foer dess framstaellning.
FI843856A0 (fi) 1-benzyl-aminoalkyl-pyrrolidinoner och deras syraadditionssalter, foerfarande foer deras framstaellning och laekemedel.
FI841128A0 (fi) Pyrimidinderivat, deras framstaellning och deras anvaendning.
FI840100A (fi) Skaeranordning foer fraesmaskin och foerfarande foer dess hopsaettning.
FI842459A0 (fi) Tetrahydropyridazinonderivat, foerfaranden foer deras framstaellning och deras anvaendning.
FI841841A (fi) 1-pyrimidinyloxi-3-hetarylalkylamino-2- propanoler, deras framstaellning och anvaendning.
FI844889A0 (fi) Foernaetade polymerater, foerfarande foer deras framstaellning och deras anvaendning.
FI834847A (fi) Voltammetriskt maetningsfoerfarande och anordning foer dess tillaempning.
FI840206A (fi) Aminosyraderivat, foerfarande foer deras framstaellning och anvaendning.
FI840428A (fi) Biologiskt aktivt ketonderivat, framstaellning och anvaendning.
FI83885B (fi) -acetolaktatdekarboxylasenzym och dess framstaellning.
FI833469A (fi) Bandblockplanta, foerfarande och anordning foer dess uppdragning och plantering.
FI842210A (fi) Kefalosporinester-derivat, deras framstaellning och anvaendning.
FI842903A0 (fi) Kolfiber och foerfarande foer dess framstaellning.
FI841615A (fi) 4-fenyl-tetrahydro-furano-pyridiner, foerfarande foer deras framstaellning och farmaceutiska blandningar.
FI841960A0 (fi) 2,6-disubstituerad-1,4- dihydropyridinderivat, foerfarande foer dess framstaellning och detta inneh aollande komposition.
FI832260L (fi) Skidbroms och foerfarande foer dess fastsaettning.
FI844002A0 (fi) Stabiliserade, inerta organiska vaetskor innehaollande natriumditionitprodukter och deras anvaendning.
FI843825L (fi) Faergkatodstraolroer, komponent och framstaellningsmetod.
FI843824L (fi) Faergkatodstraolroer, komponent och framstaellningsmetod.
FI842300A (fi) Mono- och ditioestrar, deras framstaellning och anvaendning.
FI851993A0 (fi) Kollagengel, foerfarande foer dess framstaellning och filmprodukter tillverkade av gelet.

Legal Events

Date Code Title Description
MA Patent expired

Owner name: HOKURIKU PHARMACEUTICAL CO., LTD.

MA Patent expired