YU43143B - Process for obtaining new antibiotics - Google Patents

Process for obtaining new antibiotics

Info

Publication number
YU43143B
YU43143B YU11/83A YU1183A YU43143B YU 43143 B YU43143 B YU 43143B YU 11/83 A YU11/83 A YU 11/83A YU 1183 A YU1183 A YU 1183A YU 43143 B YU43143 B YU 43143B
Authority
YU
Yugoslavia
Prior art keywords
obtaining new
new antibiotics
antibiotics
obtaining
new
Prior art date
Application number
YU11/83A
Other languages
English (en)
Other versions
YU1183A (en
Inventor
R Heymes
A Lutz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27250574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU43143(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR7601834A external-priority patent/FR2346014A1/fr
Priority claimed from FR7617743A external-priority patent/FR2361893A2/fr
Priority claimed from FR7625051A external-priority patent/FR2361894A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Priority to SI8310011A priority Critical patent/SI8310011A8/sl
Publication of YU1183A publication Critical patent/YU1183A/xx
Publication of YU43143B publication Critical patent/YU43143B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
YU11/83A 1976-01-23 1983-01-04 Process for obtaining new antibiotics YU43143B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI8310011A SI8310011A8 (sl) 1976-01-23 1983-01-04 Postopek za pridobivanje novih antibiotikov

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7617743A FR2361893A2 (fr) 1976-01-23 1976-06-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7625051A FR2361894A2 (fr) 1976-01-23 1976-08-18 Nouvelles oximes derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
YU1183A YU1183A (en) 1984-02-29
YU43143B true YU43143B (en) 1989-04-30

Family

ID=27250574

Family Applications (3)

Application Number Title Priority Date Filing Date
YU137/77A YU41060B (en) 1976-01-23 1977-01-19 Process for obtaining new antibiotics
YU00012/83A YU1283A (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics
YU11/83A YU43143B (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics

Family Applications Before (2)

Application Number Title Priority Date Filing Date
YU137/77A YU41060B (en) 1976-01-23 1977-01-19 Process for obtaining new antibiotics
YU00012/83A YU1283A (en) 1976-01-23 1983-01-04 Process for obtaining new antibiotics

Country Status (31)

Country Link
JP (3) JPS52102293A (xx)
AR (1) AR231985A1 (xx)
AT (2) AT355205B (xx)
AU (1) AU511680B2 (xx)
BE (1) BE850662A (xx)
CA (1) CA1319682C (xx)
CH (1) CH622264A5 (xx)
CY (1) CY1123A (xx)
DD (2) DD128594A5 (xx)
DE (3) DE2702501C2 (xx)
DK (1) DK161082C (xx)
ES (2) ES455089A1 (xx)
GB (2) GB1580621A (xx)
GE (1) GEP19970783B (xx)
GR (1) GR70302B (xx)
HK (1) HK50381A (xx)
HU (1) HU173110B (xx)
IE (1) IE45015B1 (xx)
IL (2) IL51192A (xx)
IT (1) IT1104601B (xx)
KE (1) KE3365A (xx)
LU (1) LU76624A1 (xx)
MX (1) MX4407E (xx)
MY (1) MY8500417A (xx)
NL (1) NL7700706A (xx)
NZ (1) NZ183150A (xx)
PL (1) PL122698B1 (xx)
PT (1) PT66099B (xx)
SE (2) SE440655B (xx)
SU (1) SU822754A3 (xx)
YU (3) YU41060B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408613A2 (fr) * 1977-07-19 1979-06-08 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
AU520269B2 (en) * 1977-03-14 1982-01-21 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
FR2448543A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461712A1 (fr) * 1979-07-23 1981-02-06 Hoechst Ag Procede de preparation de derives de cepheme
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
JPS57163386A (en) * 1981-08-13 1982-10-07 Takeda Chem Ind Ltd Cephalosporin derivative and its production
EP0238060B1 (en) 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, processes for their preparation and antibacterial agents
HUT53892A (en) * 1989-04-07 1990-12-28 Technologishen Kom Za Promy Mi Process for producing synaminothiazolyl and synaminooxazolyl derivatives
CN112457271A (zh) * 2020-11-18 2021-03-09 河北合佳医药科技集团股份有限公司 一种氨噻肟酸中间体的连续流合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法

Also Published As

Publication number Publication date
IL57445A0 (en) 1979-09-30
IT1104601B (it) 1985-10-21
JPH03204868A (ja) 1991-09-06
ATA209479A (de) 1983-06-15
DE2702501C2 (de) 1982-11-18
ES466539A1 (es) 1978-10-01
JPS52102293A (en) 1977-08-27
YU1183A (en) 1984-02-29
YU41060B (en) 1986-10-31
DK23677A (da) 1977-07-24
LU76624A1 (xx) 1977-08-12
DK161082C (da) 1991-11-04
YU13777A (en) 1983-04-30
SE440655B (sv) 1985-08-12
AT373592B (de) 1984-02-10
ATA41277A (de) 1979-07-15
DE2702501A1 (de) 1977-07-28
GR70302B (xx) 1982-09-06
CA1319682C (fr) 1993-06-29
DK161082B (da) 1991-05-27
HK50381A (en) 1981-10-30
GB1580623A (en) 1980-12-03
IL51192A0 (en) 1977-02-28
DE2760287C2 (xx) 1988-04-14
PL122698B1 (en) 1982-08-31
KE3365A (en) 1984-02-03
HU173110B (hu) 1979-02-28
NL7700706A (nl) 1977-07-26
GB1580621A (en) 1980-12-03
BE850662A (fr) 1977-07-22
IE45015L (en) 1977-07-23
JPS6228152B2 (xx) 1987-06-18
CH622264A5 (en) 1981-03-31
YU1283A (en) 1984-02-29
JPH05247013A (ja) 1993-09-24
MX4407E (es) 1982-04-27
AR231985A1 (es) 1985-04-30
CY1123A (en) 1982-02-19
PT66099B (fr) 1979-03-09
DE2759895C2 (de) 1986-01-16
PT66099A (fr) 1977-02-01
IL51192A (en) 1980-11-30
SE455307B (sv) 1988-07-04
SE7614678L (sv) 1977-07-24
ES455089A1 (es) 1978-04-16
IE45015B1 (en) 1982-06-02
SE8204893L (sv) 1982-08-26
DD128594A5 (de) 1977-11-30
AU511680B2 (en) 1980-08-28
NZ183150A (en) 1979-12-11
DD132869A5 (de) 1978-11-15
AU2157977A (en) 1978-08-03
SU822754A3 (ru) 1981-04-15
GEP19970783B (en) 1997-01-28
AT355205B (de) 1980-02-25
PL195504A1 (pl) 1978-03-13
SE8204893D0 (sv) 1982-08-26
MY8500417A (en) 1985-12-31

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