NL7700706A - Werkwijze voor de bereiding van nieuwe, van 7-aminothiazolyl-aceetamido cefalosporaanzuur afgeleide oximen. - Google Patents

Werkwijze voor de bereiding van nieuwe, van 7-aminothiazolyl-aceetamido cefalosporaanzuur afgeleide oximen.

Info

Publication number
NL7700706A
NL7700706A NL7700706A NL7700706A NL7700706A NL 7700706 A NL7700706 A NL 7700706A NL 7700706 A NL7700706 A NL 7700706A NL 7700706 A NL7700706 A NL 7700706A NL 7700706 A NL7700706 A NL 7700706A
Authority
NL
Netherlands
Prior art keywords
aceetamido
aminothiazolyl
preparation
cephalosporanic acid
oximes derived
Prior art date
Application number
NL7700706A
Other languages
English (en)
Dutch (nl)
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27250574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL7700706(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR7601834A external-priority patent/FR2346014A1/fr
Priority claimed from FR7617743A external-priority patent/FR2361893A2/fr
Priority claimed from FR7625051A external-priority patent/FR2361894A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of NL7700706A publication Critical patent/NL7700706A/xx
Priority to NLAANVRAGE8003189,A priority Critical patent/NL185208C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL7700706A 1976-01-23 1977-01-24 Werkwijze voor de bereiding van nieuwe, van 7-aminothiazolyl-aceetamido cefalosporaanzuur afgeleide oximen. NL7700706A (nl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE8003189,A NL185208C (nl) 1976-01-23 1980-10-31 Werkwijze voor de bereiding van een geneesmiddel met antibacteriele werking op basis van een antibiotisch werkzame 7-(2-(2amino-4-thiazolyl)aceetamido)cef-3-em-4-carbonzuurverbinding.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7617743A FR2361893A2 (fr) 1976-01-23 1976-06-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7625051A FR2361894A2 (fr) 1976-01-23 1976-08-18 Nouvelles oximes derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
NL7700706A true NL7700706A (nl) 1977-07-26

Family

ID=27250574

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7700706A NL7700706A (nl) 1976-01-23 1977-01-24 Werkwijze voor de bereiding van nieuwe, van 7-aminothiazolyl-aceetamido cefalosporaanzuur afgeleide oximen.

Country Status (31)

Country Link
JP (3) JPS52102293A (xx)
AR (1) AR231985A1 (xx)
AT (2) AT355205B (xx)
AU (1) AU511680B2 (xx)
BE (1) BE850662A (xx)
CA (1) CA1319682C (xx)
CH (1) CH622264A5 (xx)
CY (1) CY1123A (xx)
DD (2) DD132869A5 (xx)
DE (3) DE2702501C2 (xx)
DK (1) DK161082C (xx)
ES (2) ES455089A1 (xx)
GB (2) GB1580621A (xx)
GE (1) GEP19970783B (xx)
GR (1) GR70302B (xx)
HK (1) HK50381A (xx)
HU (1) HU173110B (xx)
IE (1) IE45015B1 (xx)
IL (2) IL51192A (xx)
IT (1) IT1104601B (xx)
KE (1) KE3365A (xx)
LU (1) LU76624A1 (xx)
MX (1) MX4407E (xx)
MY (1) MY8500417A (xx)
NL (1) NL7700706A (xx)
NZ (1) NZ183150A (xx)
PL (1) PL122698B1 (xx)
PT (1) PT66099B (xx)
SE (2) SE440655B (xx)
SU (1) SU822754A3 (xx)
YU (3) YU41060B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408613A2 (fr) * 1977-07-19 1979-06-08 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2760484C2 (xx) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
ZA781502B (en) * 1977-03-14 1979-09-26 Fujisawa Pharmaceutical Co New cephem and cepham compounds and processes for preparation thereof
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
FR2448543A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461712A1 (fr) * 1979-07-23 1981-02-06 Hoechst Ag Procede de preparation de derives de cepheme
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
JPS57163386A (en) * 1981-08-13 1982-10-07 Takeda Chem Ind Ltd Cephalosporin derivative and its production
CA1296012C (en) 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
HUT53892A (en) * 1989-04-07 1990-12-28 Technologishen Kom Za Promy Mi Process for producing synaminothiazolyl and synaminooxazolyl derivatives
CN112457271A (zh) * 2020-11-18 2021-03-09 河北合佳医药科技集团股份有限公司 一种氨噻肟酸中间体的连续流合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法

Also Published As

Publication number Publication date
CH622264A5 (en) 1981-03-31
PT66099A (fr) 1977-02-01
AT373592B (de) 1984-02-10
ATA41277A (de) 1979-07-15
AU2157977A (en) 1978-08-03
ES466539A1 (es) 1978-10-01
HU173110B (hu) 1979-02-28
PT66099B (fr) 1979-03-09
IL51192A0 (en) 1977-02-28
PL122698B1 (en) 1982-08-31
DE2702501C2 (de) 1982-11-18
SE8204893D0 (sv) 1982-08-26
AU511680B2 (en) 1980-08-28
DE2759895C2 (de) 1986-01-16
KE3365A (en) 1984-02-03
JPH03204868A (ja) 1991-09-06
GEP19970783B (en) 1997-01-28
MX4407E (es) 1982-04-27
YU1283A (en) 1984-02-29
GB1580621A (en) 1980-12-03
JPS6228152B2 (xx) 1987-06-18
AT355205B (de) 1980-02-25
DK23677A (da) 1977-07-24
HK50381A (en) 1981-10-30
IT1104601B (it) 1985-10-21
CA1319682C (fr) 1993-06-29
LU76624A1 (xx) 1977-08-12
DD132869A5 (de) 1978-11-15
AR231985A1 (es) 1985-04-30
YU13777A (en) 1983-04-30
DD128594A5 (de) 1977-11-30
ATA209479A (de) 1983-06-15
YU43143B (en) 1989-04-30
JPS52102293A (en) 1977-08-27
YU41060B (en) 1986-10-31
DE2760287C2 (xx) 1988-04-14
IE45015L (en) 1977-07-23
BE850662A (fr) 1977-07-22
SE440655B (sv) 1985-08-12
CY1123A (en) 1982-02-19
SE7614678L (sv) 1977-07-24
JPH05247013A (ja) 1993-09-24
ES455089A1 (es) 1978-04-16
GB1580623A (en) 1980-12-03
IE45015B1 (en) 1982-06-02
NZ183150A (en) 1979-12-11
YU1183A (en) 1984-02-29
GR70302B (xx) 1982-09-06
SE455307B (sv) 1988-07-04
PL195504A1 (pl) 1978-03-13
DK161082C (da) 1991-11-04
SE8204893L (sv) 1982-08-26
MY8500417A (en) 1985-12-31
IL57445A0 (en) 1979-09-30
IL51192A (en) 1980-11-30
DE2702501A1 (de) 1977-07-28
DK161082B (da) 1991-05-27
SU822754A3 (ru) 1981-04-15

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BV The patent application has lapsed
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed