ATA41277A - Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure und von deren salzen - Google Patents

Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure und von deren salzen

Info

Publication number
ATA41277A
ATA41277A AT41277A AT41277A ATA41277A AT A41277 A ATA41277 A AT A41277A AT 41277 A AT41277 A AT 41277A AT 41277 A AT41277 A AT 41277A AT A41277 A ATA41277 A AT A41277A
Authority
AT
Austria
Prior art keywords
oximens
aminothiazolylacetamidocephalosporic
salts
preparation
acid
Prior art date
Application number
AT41277A
Other languages
English (en)
Other versions
AT355205B (de
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27250574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATA41277(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR7601834A external-priority patent/FR2346014A1/fr
Priority claimed from FR7617743A external-priority patent/FR2361893A2/fr
Priority claimed from FR7625051A external-priority patent/FR2361894A2/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ATA41277A publication Critical patent/ATA41277A/de
Application granted granted Critical
Publication of AT355205B publication Critical patent/AT355205B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
AT41277A 1976-01-23 1977-01-24 Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure und von deren salzen AT355205B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7601834A FR2346014A1 (fr) 1976-01-23 1976-01-23 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7617743A FR2361893A2 (fr) 1976-01-23 1976-06-11 Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR7625051A FR2361894A2 (fr) 1976-01-23 1976-08-18 Nouvelles oximes derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
ATA41277A true ATA41277A (de) 1979-07-15
AT355205B AT355205B (de) 1980-02-25

Family

ID=27250574

Family Applications (2)

Application Number Title Priority Date Filing Date
AT41277A AT355205B (de) 1976-01-23 1977-01-24 Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure und von deren salzen
AT0209479A AT373592B (de) 1976-01-23 1979-03-20 Verfahren zur herstellung von neuen 4-thiazolyl-oximen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0209479A AT373592B (de) 1976-01-23 1979-03-20 Verfahren zur herstellung von neuen 4-thiazolyl-oximen

Country Status (31)

Country Link
JP (3) JPS52102293A (de)
AR (1) AR231985A1 (de)
AT (2) AT355205B (de)
AU (1) AU511680B2 (de)
BE (1) BE850662A (de)
CA (1) CA1319682C (de)
CH (1) CH622264A5 (de)
CY (1) CY1123A (de)
DD (2) DD132869A5 (de)
DE (3) DE2702501C2 (de)
DK (1) DK161082C (de)
ES (2) ES455089A1 (de)
GB (2) GB1580621A (de)
GE (1) GEP19970783B (de)
GR (1) GR70302B (de)
HK (1) HK50381A (de)
HU (1) HU173110B (de)
IE (1) IE45015B1 (de)
IL (2) IL51192A (de)
IT (1) IT1104601B (de)
KE (1) KE3365A (de)
LU (1) LU76624A1 (de)
MX (1) MX4407E (de)
MY (1) MY8500417A (de)
NL (1) NL7700706A (de)
NZ (1) NZ183150A (de)
PL (1) PL122698B1 (de)
PT (1) PT66099B (de)
SE (2) SE440655B (de)
SU (1) SU822754A3 (de)
YU (3) YU41060B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2408613A2 (fr) * 1977-07-19 1979-06-08 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DE2760484C2 (de) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
ZA781502B (en) * 1977-03-14 1979-09-26 Fujisawa Pharmaceutical Co New cephem and cepham compounds and processes for preparation thereof
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2400519A1 (fr) * 1977-08-17 1979-03-16 Roussel Uclaf Forme cristalline du sel de sodium d'un derive oximine de l'acide 7-amino-thiazolyl acetamido cephalosporanique, son procede de preparation et son application comme medicament
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
FR2432521A1 (fr) * 1978-03-31 1980-02-29 Roussel Uclaf Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
SE445350B (sv) * 1978-04-14 1986-06-16 Roussel Uclaf Oximderivat av 3-azidometyl-7-amino-tiazolyl-acetamido-cefalosporansyra och dess anvendning som antibiotika
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
FR2448543A1 (fr) * 1979-02-09 1980-09-05 Roussel Uclaf Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) * 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461712A1 (fr) * 1979-07-23 1981-02-06 Hoechst Ag Procede de preparation de derives de cepheme
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
JPS57163386A (en) * 1981-08-13 1982-10-07 Takeda Chem Ind Ltd Cephalosporin derivative and its production
EP0238060B1 (de) 1986-03-19 1992-01-08 Banyu Pharmaceutical Co., Ltd. Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und antibakterielle Mittel
HUT53892A (en) * 1989-04-07 1990-12-28 Technologishen Kom Za Promy Mi Process for producing synaminothiazolyl and synaminooxazolyl derivatives
CN112457271A (zh) * 2020-11-18 2021-03-09 河北合佳医药科技集团股份有限公司 一种氨噻肟酸中间体的连续流合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法

Also Published As

Publication number Publication date
AT373592B (de) 1984-02-10
JPS6228152B2 (de) 1987-06-18
CH622264A5 (en) 1981-03-31
SE455307B (sv) 1988-07-04
NZ183150A (en) 1979-12-11
SE8204893D0 (sv) 1982-08-26
AR231985A1 (es) 1985-04-30
CY1123A (en) 1982-02-19
SE7614678L (sv) 1977-07-24
MY8500417A (en) 1985-12-31
GB1580623A (en) 1980-12-03
JPH05247013A (ja) 1993-09-24
YU13777A (en) 1983-04-30
IE45015B1 (en) 1982-06-02
YU1283A (en) 1984-02-29
KE3365A (en) 1984-02-03
MX4407E (es) 1982-04-27
IL51192A (en) 1980-11-30
ES455089A1 (es) 1978-04-16
YU43143B (en) 1989-04-30
SE440655B (sv) 1985-08-12
AU511680B2 (en) 1980-08-28
PL195504A1 (pl) 1978-03-13
AU2157977A (en) 1978-08-03
DK161082C (da) 1991-11-04
CA1319682C (fr) 1993-06-29
ES466539A1 (es) 1978-10-01
DK161082B (da) 1991-05-27
NL7700706A (nl) 1977-07-26
IE45015L (en) 1977-07-23
DE2759895C2 (de) 1986-01-16
JPH03204868A (ja) 1991-09-06
LU76624A1 (de) 1977-08-12
GR70302B (de) 1982-09-06
JPS52102293A (en) 1977-08-27
HK50381A (en) 1981-10-30
GB1580621A (en) 1980-12-03
PT66099A (fr) 1977-02-01
YU1183A (en) 1984-02-29
HU173110B (hu) 1979-02-28
ATA209479A (de) 1983-06-15
IT1104601B (it) 1985-10-21
PL122698B1 (en) 1982-08-31
AT355205B (de) 1980-02-25
IL51192A0 (en) 1977-02-28
GEP19970783B (en) 1997-01-28
DE2760287C2 (de) 1988-04-14
DD132869A5 (de) 1978-11-15
DK23677A (da) 1977-07-24
DE2702501A1 (de) 1977-07-28
SE8204893L (sv) 1982-08-26
IL57445A0 (en) 1979-09-30
DD128594A5 (de) 1977-11-30
YU41060B (en) 1986-10-31
BE850662A (fr) 1977-07-22
DE2702501C2 (de) 1982-11-18
PT66099B (fr) 1979-03-09
SU822754A3 (ru) 1981-04-15

Similar Documents

Publication Publication Date Title
ATA812076A (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saureadditionssalzen
ATA195476A (de) Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
ATA48979A (de) Verfahren zur herstellung von neuen pyridinyl-2 (1h)-pyridinonen und deren saeureadditionssalzen
ATA41277A (de) Verfahren zur herstellung von neuen oximen der 7-aminothiazolylacetamidocephalosporansaeure und von deren salzen
AT352709B (de) Verfahren zur herstellung von neuen benzothio- phenderivaten und von deren saeureadditions- salzen
ATA308377A (de) Verfahren zur herstellung von neuen omega- aminocarbondsaeurederivaten und deren salzen
ATA592975A (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saureadditionssalzen
AT352137B (de) Verfahren zur herstellung von neuen piperazinylbenzopyron-derivaten und deren salzen
ATA195576A (de) Verfahren zur herstellung von neuen p-halogen-acylophenon- o - (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT348524B (de) Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saeureadditionssalzen
ATA194876A (de) Verfahren zur herstellung von neuen p-methylthioacylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT352735B (de) Verfahren zur herstellung von neuen 2,4- diamino-5-benzylpyrimidinen und deren saeure- additionssalzen
AT354440B (de) Verfahren zur herstellung von neuen thiazolidinderivaten und von deren saeure- additionssalzen
AT340051B (de) Verfahren zur herstellung von neuen 2-deoxystreptaminaminoglykosiden und deren saureadditionssalzen
ATA195276A (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl) -oximather und deren saureadditionssalzen
ATA195176A (de) Verfahren zur herstellung von neuen p-methylsulfinyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT347956B (de) Verfahren zur herstellung von neuen chinol-2- on-4-yl-alkansaeuren und von deren basenadditionssalzen
ATA488876A (de) Verfahren zur herstellung von neuen 3-hydroxycrontonsaeureazetidinderivaten und deren salzen
AT342571B (de) Verfahren zur herstellung von neuen p- methylthio-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA27577A (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA317177A (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT342022B (de) Verfahren zur herstellung von neuen p-methylsulfinylacylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT342568B (de) Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
ATA27377A (de) Verfahren zur herstellung von neuen p-methylthio-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA341977A (de) Verfahren zur herstellung von neuen p-methylsulfinyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time