YU34395B - Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes - Google Patents

Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes

Info

Publication number
YU34395B
YU34395B YU1860/70A YU186070A YU34395B YU 34395 B YU34395 B YU 34395B YU 1860/70 A YU1860/70 A YU 1860/70A YU 186070 A YU186070 A YU 186070A YU 34395 B YU34395 B YU 34395B
Authority
YU
Yugoslavia
Prior art keywords
aminopropanes
phenoxy
cycloalkyl
hydroxy
preparing novel
Prior art date
Application number
YU1860/70A
Other languages
English (en)
Other versions
YU186070A (en
Inventor
Koeppe Herbert
Herbert Koeppe
Kummer Werner
Werner Kummer
Staehle Helmut
Helmut Staehle
Zeile Karl
Karl Zeile
Engelhardt Albrecht
Albrecht Engelhardt
Traunecker Werner
Werner Traunecker
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to YU254975A priority Critical patent/YU34191B/xx
Priority to YU254775A priority patent/YU34190B/xx
Publication of YU186070A publication Critical patent/YU186070A/xx
Publication of YU34395B publication Critical patent/YU34395B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H13/00—Monuments; Tombs; Burial vaults; Columbaria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Architecture (AREA)
  • Structural Engineering (AREA)
  • Civil Engineering (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
YU1860/70A 1969-07-23 1970-07-22 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes YU34395B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
YU254975A YU34191B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxyl3-cycloalkyl-aminopropanes
YU254775A YU34190B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1937477A DE1937477C3 (de) 1969-07-23 1969-07-23 I -Phenoxy-2-hydroxy-3-(l -methylcycloalkylamino)-propane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
YU186070A YU186070A (en) 1978-12-31
YU34395B true YU34395B (en) 1979-07-10

Family

ID=5740681

Family Applications (5)

Application Number Title Priority Date Filing Date
YU1860/70A YU34395B (en) 1969-07-23 1970-07-22 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes
YU2545/75A YU34662B (en) 1969-07-23 1975-10-07 Process for preparin novel 1-phenoxy-2-hydroxy-3-cycloalkyl-amino - propanes
YU2544/75A YU34396B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes
YU2551/75A YU34113B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes
YU2546/75A YU34663B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-amino-propanes

Family Applications After (4)

Application Number Title Priority Date Filing Date
YU2545/75A YU34662B (en) 1969-07-23 1975-10-07 Process for preparin novel 1-phenoxy-2-hydroxy-3-cycloalkyl-amino - propanes
YU2544/75A YU34396B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes
YU2551/75A YU34113B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-aminopropanes
YU2546/75A YU34663B (en) 1969-07-23 1975-10-07 Process for preparing novel 1-phenoxy-2-hydroxy-3-cycloalkyl-amino-propanes

Country Status (17)

Country Link
US (1) US3755413A (ja)
JP (5) JPS5133106B1 (ja)
AT (9) AT304474B (ja)
BE (1) BE753774A (ja)
BG (9) BG17508A3 (ja)
CH (10) CH570363A5 (ja)
CS (9) CS170524B2 (ja)
DE (1) DE1937477C3 (ja)
DK (1) DK140281B (ja)
ES (8) ES382014A1 (ja)
FR (1) FR2059551B1 (ja)
GB (1) GB1314896A (ja)
NL (1) NL169874C (ja)
PL (9) PL79772B1 (ja)
RO (9) RO59159A (ja)
SE (1) SE370391B (ja)
YU (5) YU34395B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3937706A (en) * 1969-07-23 1976-02-10 Boehringer Ingelheim Gmbh 1-(2'ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propanes and salts thereof
US4021576A (en) * 1969-07-23 1977-05-03 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-(2'-ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propane and method of use
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4120978A (en) * 1970-01-08 1978-10-17 Ciba-Geigy Corporation Pharmaceutical composition for inhibiting and blocking cardioselective beta-receptors
SE354851B (ja) * 1970-02-18 1973-03-26 Haessle Ab
US4145442A (en) * 1972-04-04 1979-03-20 Aktiebolaget Hassle Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4220659A (en) * 1974-02-22 1980-09-02 Boehringer Ingelheim Gmbh 1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof
SE7510153L (sv) * 1974-09-12 1976-05-07 American Cyanamid Co Alkanolaminer
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4471127A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1-5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US5039801A (en) * 1985-12-20 1991-08-13 The United States Of America As Represented By The Department Of Health & Human Services Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
JPS6364630U (ja) * 1986-10-17 1988-04-28

Also Published As

Publication number Publication date
CS170524B2 (ja) 1976-08-27
PL90026B1 (ja) 1976-12-31
NL169874B (nl) 1982-04-01
CS170525B2 (ja) 1976-08-27
YU34663B (en) 1979-12-31
YU34396B (en) 1979-07-10
AT304477B (de) 1973-01-10
RO59210A (ja) 1976-01-15
PL79772B1 (ja) 1975-06-30
BG17505A3 (bg) 1973-11-10
CH537360A (de) 1973-05-31
US3755413A (en) 1973-08-28
YU255175A (en) 1978-06-30
BG17507A3 (bg) 1973-11-10
YU254575A (en) 1979-04-30
JPS5210862B1 (ja) 1977-03-26
CH536811A (de) 1973-06-29
CH536809A (de) 1973-06-29
DE1937477C3 (de) 1980-04-10
BG19132A3 (bg) 1975-04-30
YU186070A (en) 1978-12-31
BG17751A3 (bg) 1973-12-25
PL90028B1 (ja) 1976-12-31
NL7010928A (ja) 1971-01-26
JPS5210863B1 (ja) 1977-03-26
AT306702B (de) 1973-04-25
AT304476B (de) 1973-01-10
FR2059551B1 (ja) 1974-09-20
SE370391B (ja) 1974-10-14
CH536813A (de) 1973-06-29
AT306704B (de) 1973-04-25
BG17506A3 (bg) 1973-11-10
CH570363A5 (ja) 1975-12-15
AT304478B (de) 1973-01-10
RO59089A (ja) 1975-11-15
BG17749A3 (bg) 1973-12-25
YU254475A (en) 1978-12-31
ES394913A1 (es) 1974-12-16
CS170527B2 (ja) 1976-08-27
JPS5133106B1 (ja) 1976-09-17
RO59159A (ja) 1976-02-15
YU34662B (en) 1979-12-31
AT306703B (de) 1973-04-25
PL90039B1 (ja) 1976-12-31
ES394915A1 (es) 1974-12-16
CH550140A (de) 1974-06-14
RO59112A (ja) 1976-01-15
AT304475B (de) 1973-01-10
CS170528B2 (ja) 1976-08-27
RO59209A (ja) 1976-01-15
RO59211A (ja) 1976-01-15
RO60111A (ja) 1976-06-15
FR2059551A1 (ja) 1971-06-04
BG17750A3 (bg) 1973-12-25
ES394916A1 (es) 1974-12-16
DK140281B (da) 1979-07-23
CH536812A (de) 1973-06-29
RO56318A (ja) 1974-09-01
CS170530B2 (ja) 1976-08-27
ES394919A1 (es) 1974-12-01
RO60112A (ja) 1976-08-15
NL169874C (nl) 1982-09-01
DE1937477B2 (de) 1979-08-02
JPS5238556B1 (ja) 1977-09-29
BG17508A3 (bg) 1973-11-10
ES394918A1 (es) 1974-12-01
PL90029B1 (ja) 1976-12-31
YU254675A (en) 1979-04-30
ES394914A1 (es) 1974-12-01
JPS5210861B1 (ja) 1977-03-26
CS170529B2 (ja) 1976-08-27
CS170526B2 (ja) 1976-08-27
BG18852A3 (bg) 1975-03-20
PL90030B1 (ja) 1976-12-31
CH575376A5 (ja) 1976-05-14
YU34113B (en) 1978-12-31
AT303706B (de) 1972-12-11
CH536810A (de) 1973-06-29
AT304474B (de) 1973-01-10
GB1314896A (en) 1973-04-26
PL90038B1 (ja) 1976-12-31
DE1937477A1 (de) 1971-02-04
CS170531B2 (ja) 1976-08-27
CH550139A (de) 1974-06-14
DK140281C (ja) 1979-12-10
ES394917A1 (es) 1974-12-01
PL90027B1 (ja) 1976-12-31
BE753774A (fr) 1971-01-22
ES382014A1 (es) 1973-06-16
PL90025B1 (ja) 1976-12-31
CS170532B2 (ja) 1976-08-27

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