ES394916A1 - Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos. - Google Patents

Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.

Info

Publication number
ES394916A1
ES394916A1 ES394916A ES394916A ES394916A1 ES 394916 A1 ES394916 A1 ES 394916A1 ES 394916 A ES394916 A ES 394916A ES 394916 A ES394916 A ES 394916A ES 394916 A1 ES394916 A1 ES 394916A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
halogen atom
alcohol
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES394916A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES394916A1 publication Critical patent/ES394916A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • E—FIXED CONSTRUCTIONS
    • E04—BUILDING
    • E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H13/00—Monuments; Tombs; Burial vaults; Columbaria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
ES394916A 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos. Expired ES394916A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1937477A DE1937477C3 (de) 1969-07-23 1969-07-23 I -Phenoxy-2-hydroxy-3-(l -methylcycloalkylamino)-propane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ES394916A1 true ES394916A1 (es) 1974-12-16

Family

ID=5740681

Family Applications (8)

Application Number Title Priority Date Filing Date
ES382014A Expired ES382014A1 (es) 1969-07-23 1970-07-21 Procedimiento para la preparacion de 1-fenoxi-2-hidroxi - - 3 - cicloalcohilaminopropanos racemicos u opticamente ac- tivados y sus sales por adicion de acido.
ES394919A Expired ES394919A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394915A Expired ES394915A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394917A Expired ES394917A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394913A Expired ES394913A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394916A Expired ES394916A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394918A Expired ES394918A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente activos.
ES394914A Expired ES394914A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES382014A Expired ES382014A1 (es) 1969-07-23 1970-07-21 Procedimiento para la preparacion de 1-fenoxi-2-hidroxi - - 3 - cicloalcohilaminopropanos racemicos u opticamente ac- tivados y sus sales por adicion de acido.
ES394919A Expired ES394919A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394915A Expired ES394915A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394917A Expired ES394917A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.
ES394913A Expired ES394913A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES394918A Expired ES394918A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente activos.
ES394914A Expired ES394914A1 (es) 1969-07-23 1971-09-09 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi - 3 - alcohilaminopropanos racemicos u opticamente ac-tivos.

Country Status (17)

Country Link
US (1) US3755413A (es)
JP (5) JPS5133106B1 (es)
AT (9) AT304476B (es)
BE (1) BE753774A (es)
BG (9) BG17508A3 (es)
CH (10) CH536813A (es)
CS (9) CS170532B2 (es)
DE (1) DE1937477C3 (es)
DK (1) DK140281B (es)
ES (8) ES382014A1 (es)
FR (1) FR2059551B1 (es)
GB (1) GB1314896A (es)
NL (1) NL169874C (es)
PL (9) PL90026B1 (es)
RO (9) RO59112A (es)
SE (1) SE370391B (es)
YU (5) YU34395B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021576A (en) * 1969-07-23 1977-05-03 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing a 1-(2'-ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propane and method of use
US3937706A (en) * 1969-07-23 1976-02-10 Boehringer Ingelheim Gmbh 1-(2'ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propanes and salts thereof
US4120978A (en) * 1970-01-08 1978-10-17 Ciba-Geigy Corporation Pharmaceutical composition for inhibiting and blocking cardioselective beta-receptors
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
SE354851B (es) * 1970-02-18 1973-03-26 Haessle Ab
US4145442A (en) * 1972-04-04 1979-03-20 Aktiebolaget Hassle Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
US4038414A (en) * 1972-06-08 1977-07-26 Ciba-Geigy Corporation Amines and processes for their manufacture
US4035420A (en) * 1972-07-06 1977-07-12 Aktiebolaget Hassle Substituted ureido alkylene phenoxy propanolamines
DE2309887C2 (de) * 1973-02-28 1983-11-10 C.H. Boehringer Sohn, 6507 Ingelheim 1-Aryloxy-2-hydroxy-3-alkinylaminopropan-Derivate und deren physiologisch verträgliche Säureadditionssalze, pharmazeutische Präparate und Herstellungsverfahren für die Verbindungen
US4220659A (en) * 1974-02-22 1980-09-02 Boehringer Ingelheim Gmbh 1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof
DE2540552A1 (de) * 1974-09-12 1976-03-25 American Cyanamid Co Cycloalkylderivate von 1-aryloxy-3- amino-2-propanolen
US4165384A (en) * 1974-11-01 1979-08-21 Aktiebolaget Hassle Amide substituted phenoxy propanol amines
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4471127A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1-5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US5039801A (en) * 1985-12-20 1991-08-13 The United States Of America As Represented By The Department Of Health & Human Services Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
JPS6364630U (es) * 1986-10-17 1988-04-28

Also Published As

Publication number Publication date
AT304476B (de) 1973-01-10
JPS5133106B1 (es) 1976-09-17
CS170524B2 (es) 1976-08-27
YU34113B (en) 1978-12-31
CH550139A (de) 1974-06-14
FR2059551A1 (es) 1971-06-04
CS170528B2 (es) 1976-08-27
RO59159A (es) 1976-02-15
JPS5210861B1 (es) 1977-03-26
JPS5210862B1 (es) 1977-03-26
PL90027B1 (es) 1976-12-31
BG17751A3 (es) 1973-12-25
CH575376A5 (es) 1976-05-14
CH550140A (de) 1974-06-14
NL7010928A (es) 1971-01-26
YU34395B (en) 1979-07-10
DE1937477C3 (de) 1980-04-10
YU186070A (en) 1978-12-31
BG18852A3 (es) 1975-03-20
CH536811A (de) 1973-06-29
RO59210A (es) 1976-01-15
FR2059551B1 (es) 1974-09-20
CS170531B2 (es) 1976-08-27
BG17505A3 (es) 1973-11-10
AT304477B (de) 1973-01-10
RO59089A (es) 1975-11-15
CH536809A (de) 1973-06-29
PL90038B1 (es) 1976-12-31
PL90029B1 (es) 1976-12-31
YU254675A (en) 1979-04-30
DE1937477B2 (de) 1979-08-02
CS170532B2 (es) 1976-08-27
PL90030B1 (es) 1976-12-31
PL79772B1 (es) 1975-06-30
NL169874C (nl) 1982-09-01
RO60112A (es) 1976-08-15
BE753774A (fr) 1971-01-22
RO56318A (es) 1974-09-01
PL90025B1 (es) 1976-12-31
CH536812A (de) 1973-06-29
RO60111A (es) 1976-06-15
ES394915A1 (es) 1974-12-16
RO59209A (es) 1976-01-15
ES394914A1 (es) 1974-12-01
YU34662B (en) 1979-12-31
DK140281C (es) 1979-12-10
BG17506A3 (es) 1973-11-10
CH570363A5 (es) 1975-12-15
RO59211A (es) 1976-01-15
YU254575A (en) 1979-04-30
SE370391B (es) 1974-10-14
GB1314896A (en) 1973-04-26
AT306702B (de) 1973-04-25
AT304478B (de) 1973-01-10
CS170527B2 (es) 1976-08-27
BG19132A3 (es) 1975-04-30
ES394917A1 (es) 1974-12-01
YU254475A (en) 1978-12-31
JPS5210863B1 (es) 1977-03-26
YU255175A (en) 1978-06-30
JPS5238556B1 (es) 1977-09-29
PL90028B1 (es) 1976-12-31
CS170526B2 (es) 1976-08-27
BG17750A3 (es) 1973-12-25
CH537360A (de) 1973-05-31
DE1937477A1 (de) 1971-02-04
ES394918A1 (es) 1974-12-01
CS170529B2 (es) 1976-08-27
AT303706B (de) 1972-12-11
CH536810A (de) 1973-06-29
ES394919A1 (es) 1974-12-01
BG17749A3 (es) 1973-12-25
BG17507A3 (es) 1973-11-10
ES382014A1 (es) 1973-06-16
PL90039B1 (es) 1976-12-31
BG17508A3 (es) 1973-11-10
PL90026B1 (es) 1976-12-31
RO59112A (es) 1976-01-15
DK140281B (da) 1979-07-23
AT304475B (de) 1973-01-10
YU34663B (en) 1979-12-31
CS170525B2 (es) 1976-08-27
CH536813A (de) 1973-06-29
YU34396B (en) 1979-07-10
AT304474B (de) 1973-01-10
CS170530B2 (es) 1976-08-27
NL169874B (nl) 1982-04-01
ES394913A1 (es) 1974-12-16
US3755413A (en) 1973-08-28
AT306703B (de) 1973-04-25
AT306704B (de) 1973-04-25

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