YU33594A - Postupak za proizvodnju aminoalkilgvanidina - Google Patents

Postupak za proizvodnju aminoalkilgvanidina

Info

Publication number
YU33594A
YU33594A YU33594A YU33594A YU33594A YU 33594 A YU33594 A YU 33594A YU 33594 A YU33594 A YU 33594A YU 33594 A YU33594 A YU 33594A YU 33594 A YU33594 A YU 33594A
Authority
YU
Yugoslavia
Prior art keywords
pct
date
production
sec
jun
Prior art date
Application number
YU33594A
Other languages
English (en)
Inventor
J.E. Nystrom
Hans Frederik Sjobom
Original Assignee
Aktiebolaget Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Astra filed Critical Aktiebolaget Astra
Publication of YU33594A publication Critical patent/YU33594A/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Postupak za proizvodnju gvanidino zaštićenih w-aminoalkil gvanidina opšte formule III H2N-CnH2n-NH-C(=NH)-NH-C(0)-0-R (III) gde je -CnH2n - jedna alkilna grupa pravog ili račvastog niza, n je ceo broj od 2 do 18, a R se bira iz grupe koja se sastoji od jedne C1-C12 - alkilne grupe kao što je neki niži alkil, i jedne aralkilne grupe kao što je benzil ili supstituisani benzil, reagovanjem diamina selektivno kod jedne amino grupe sa alkoksikarbonilom ili aralkoksikarbonilno zaštićenim elektrofilnim sredstvom za galvanizaciju. Postupak prema pronalasku je opšti i može se izvesti u jednom stupnju, a daje proizvod velike čistoće i u upotrebljivim količinama. Pronalazak se dalje odnosi na neka jedinjenja koja su sama po sebi nova, kao i na neka nova jedinjenja koja se koriste u postupku prema pronalasku.
YU33594A 1993-06-03 1994-06-03 Postupak za proizvodnju aminoalkilgvanidina YU33594A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19939301912A SE9301912D0 (sv) 1993-06-03 1993-06-03 Process for the production of aminoalkylguandines

Publications (1)

Publication Number Publication Date
YU33594A true YU33594A (sh) 1997-05-28

Family

ID=20390162

Family Applications (1)

Application Number Title Priority Date Filing Date
YU33594A YU33594A (sh) 1993-06-03 1994-06-03 Postupak za proizvodnju aminoalkilgvanidina

Country Status (27)

Country Link
US (1) US5659071A (sh)
EP (1) EP0701550B1 (sh)
JP (1) JP3662925B2 (sh)
CN (1) CN1124956A (sh)
AT (1) ATE178316T1 (sh)
AU (1) AU674970B2 (sh)
BR (1) BR9406713A (sh)
CA (1) CA2162920C (sh)
CZ (1) CZ320095A3 (sh)
DE (1) DE69417554T2 (sh)
DK (1) DK0701550T3 (sh)
EE (1) EE9400348A (sh)
ES (1) ES2131688T3 (sh)
FI (1) FI120093B (sh)
GR (1) GR3030501T3 (sh)
HR (1) HRP940317A2 (sh)
HU (1) HUT74293A (sh)
IL (1) IL109683A0 (sh)
IS (1) IS4165A (sh)
LT (1) LT3309B (sh)
NO (1) NO305514B1 (sh)
NZ (1) NZ267192A (sh)
PL (1) PL311760A1 (sh)
SE (1) SE9301912D0 (sh)
SK (1) SK151895A3 (sh)
WO (1) WO1994029269A1 (sh)
YU (1) YU33594A (sh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610308A (en) * 1995-05-18 1997-03-11 Bristol-Myers Squibb Company Process for preparing intermediates for thrombin inhibitors
ATE236192T1 (de) * 1995-12-09 2003-04-15 Akzo Nobel Nv 3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaften
AR035216A1 (es) * 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
AR034517A1 (es) 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
SE0201659D0 (sv) * 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
US7781424B2 (en) * 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
US7524354B2 (en) * 2005-07-07 2009-04-28 Research Foundation Of State University Of New York Controlled synthesis of highly monodispersed gold nanoparticles
CN101489655A (zh) 2006-07-14 2009-07-22 威斯康星旧生研究基金会 捕获病毒用吸附膜
TW200827336A (en) * 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
US20090061000A1 (en) * 2007-08-31 2009-03-05 Astrazeneca Ab Pharmaceutical formulation use 030
JP6006634B2 (ja) * 2011-12-28 2016-10-12 東和薬品株式会社 イソウレア化合物を用いるエピナスチンの製造方法
JP6484220B2 (ja) * 2014-03-28 2019-03-13 株式会社カネカ トリ−カルボベンゾキシ−アルギニンの製造方法
US20220002238A1 (en) * 2018-11-07 2022-01-06 Regents Of The University Of Minnesota Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE463576C (de) * 1924-08-06 1928-07-31 Schering Kahlbaum Akt Ges Verfahren zur Darstellung von Aminoguanidinen oder deren Salzen
FR2294699A1 (fr) * 1974-12-19 1976-07-16 Bottu Nouveaux derives du pyrazole et compositions pharmaceutiques les renfermant
HU178398B (en) 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4387049A (en) 1982-02-22 1983-06-07 Smithkline Beckman Corporation Adamantyl containing peptides
DE3222342A1 (de) * 1982-06-14 1983-12-15 Hoechst Ag, 6230 Frankfurt 6-aryl-1,2,4-triazolo (4,3-b) pyridazin-3-carbaminate, ihre herstellung und sie enthaltende arzneimittel
US4914189A (en) * 1987-02-05 1990-04-03 The Adminstrators Of The Tulane Educational Fund Synthetic GHRH analogs
AU2306592A (en) * 1991-07-03 1993-02-11 E.I. Du Pont De Nemours And Company Azeotropic or azeotrope-like compositions of pentafluoroethane and propane or isobutane
US5498724A (en) * 1994-06-28 1996-03-12 Aktiebolaget Astra Pyrazoleamidine compounds

Also Published As

Publication number Publication date
JPH08511016A (ja) 1996-11-19
JP3662925B2 (ja) 2005-06-22
AU6940494A (en) 1995-01-03
EE9400348A (et) 1996-04-15
HUT74293A (en) 1996-11-28
NZ267192A (en) 1997-03-24
NO305514B1 (no) 1999-06-14
SE9301912D0 (sv) 1993-06-03
GR3030501T3 (en) 1999-10-29
LTIP1940A (en) 1994-12-27
ATE178316T1 (de) 1999-04-15
ES2131688T3 (es) 1999-08-01
EP0701550A1 (en) 1996-03-20
CA2162920C (en) 2005-08-09
LT3309B (en) 1995-06-26
DK0701550T3 (da) 1999-10-11
CA2162920A1 (en) 1994-12-22
WO1994029269A1 (en) 1994-12-22
FI955800A (fi) 1995-12-01
FI120093B (fi) 2009-06-30
CN1124956A (zh) 1996-06-19
EP0701550B1 (en) 1999-03-31
AU674970B2 (en) 1997-01-16
IS4165A (is) 1994-12-04
DE69417554D1 (de) 1999-05-06
US5659071A (en) 1997-08-19
HU9503444D0 (en) 1996-01-29
BR9406713A (pt) 1996-03-19
PL311760A1 (en) 1996-03-18
NO954835L (no) 1995-11-28
CZ320095A3 (en) 1996-07-17
IL109683A0 (en) 1994-08-26
DE69417554T2 (de) 1999-09-02
NO954835D0 (no) 1995-11-28
SK151895A3 (en) 1996-04-03
FI955800A0 (fi) 1995-12-01
HRP940317A2 (en) 1996-10-31

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