DK0701550T3 - Fremgangsmåde til fremstilling af aminoalkylguanidiner - Google Patents

Fremgangsmåde til fremstilling af aminoalkylguanidiner

Info

Publication number
DK0701550T3
DK0701550T3 DK94917867T DK94917867T DK0701550T3 DK 0701550 T3 DK0701550 T3 DK 0701550T3 DK 94917867 T DK94917867 T DK 94917867T DK 94917867 T DK94917867 T DK 94917867T DK 0701550 T3 DK0701550 T3 DK 0701550T3
Authority
DK
Denmark
Prior art keywords
pct
date
sec
jun
preparation
Prior art date
Application number
DK94917867T
Other languages
English (en)
Inventor
Jan-Erik Nystrim
Hans Fredrik Sjibom
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of DK0701550T3 publication Critical patent/DK0701550T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
DK94917867T 1993-06-03 1994-06-01 Fremgangsmåde til fremstilling af aminoalkylguanidiner DK0701550T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939301912A SE9301912D0 (sv) 1993-06-03 1993-06-03 Process for the production of aminoalkylguandines
PCT/SE1994/000517 WO1994029269A1 (en) 1993-06-03 1994-06-01 Process for the production of aminoalkylguanidines

Publications (1)

Publication Number Publication Date
DK0701550T3 true DK0701550T3 (da) 1999-10-11

Family

ID=20390162

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94917867T DK0701550T3 (da) 1993-06-03 1994-06-01 Fremgangsmåde til fremstilling af aminoalkylguanidiner

Country Status (27)

Country Link
US (1) US5659071A (da)
EP (1) EP0701550B1 (da)
JP (1) JP3662925B2 (da)
CN (1) CN1124956A (da)
AT (1) ATE178316T1 (da)
AU (1) AU674970B2 (da)
BR (1) BR9406713A (da)
CA (1) CA2162920C (da)
CZ (1) CZ320095A3 (da)
DE (1) DE69417554T2 (da)
DK (1) DK0701550T3 (da)
EE (1) EE9400348A (da)
ES (1) ES2131688T3 (da)
FI (1) FI120093B (da)
GR (1) GR3030501T3 (da)
HR (1) HRP940317A2 (da)
HU (1) HUT74293A (da)
IL (1) IL109683A0 (da)
IS (1) IS4165A (da)
LT (1) LT3309B (da)
NO (1) NO305514B1 (da)
NZ (1) NZ267192A (da)
PL (1) PL311760A1 (da)
SE (1) SE9301912D0 (da)
SK (1) SK151895A3 (da)
WO (1) WO1994029269A1 (da)
YU (1) YU33594A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610308A (en) * 1995-05-18 1997-03-11 Bristol-Myers Squibb Company Process for preparing intermediates for thrombin inhibitors
DE69627184D1 (de) * 1995-12-09 2003-05-08 Akzo Nobel Nv 3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaften
US7129233B2 (en) 2000-12-01 2006-10-31 Astrazeneca Ab Mandelic acid derivatives and their use as thrombin inhibitors
AR035216A1 (es) 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
FR2822463B1 (fr) 2001-03-21 2004-07-30 Lipha Derives bicycliques de guanidines et leurs applications en therapeutique
AR034517A1 (es) 2001-06-21 2004-02-25 Astrazeneca Ab Formulacion farmaceutica
SE0201661D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab New salts
SE0201659D0 (sv) 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
US7781424B2 (en) * 2003-05-27 2010-08-24 Astrazeneca Ab Modified release pharmaceutical formulation
US7524354B2 (en) * 2005-07-07 2009-04-28 Research Foundation Of State University Of New York Controlled synthesis of highly monodispersed gold nanoparticles
WO2008008872A2 (en) 2006-07-14 2008-01-17 Wisconsin Alumni Research Foundation Adsorptive membranes for trapping viruses
TW200827336A (en) 2006-12-06 2008-07-01 Astrazeneca Ab New crystalline forms
US20090061000A1 (en) * 2007-08-31 2009-03-05 Astrazeneca Ab Pharmaceutical formulation use 030
JP6006634B2 (ja) * 2011-12-28 2016-10-12 東和薬品株式会社 イソウレア化合物を用いるエピナスチンの製造方法
US10202337B2 (en) * 2014-03-28 2019-02-12 Kaneka Corporation Method for producing tri-carbobenzoxy-arginine
US20220002238A1 (en) * 2018-11-07 2022-01-06 Regents Of The University Of Minnesota Analgesic and anti-addictive compositions for treatment of chronic pain and opioid addiction

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE463576C (de) * 1924-08-06 1928-07-31 Schering Kahlbaum Akt Ges Verfahren zur Darstellung von Aminoguanidinen oder deren Salzen
FR2294699A1 (fr) * 1974-12-19 1976-07-16 Bottu Nouveaux derives du pyrazole et compositions pharmaceutiques les renfermant
HU178398B (en) 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4387049A (en) 1982-02-22 1983-06-07 Smithkline Beckman Corporation Adamantyl containing peptides
DE3222342A1 (de) * 1982-06-14 1983-12-15 Hoechst Ag, 6230 Frankfurt 6-aryl-1,2,4-triazolo (4,3-b) pyridazin-3-carbaminate, ihre herstellung und sie enthaltende arzneimittel
US4914189A (en) * 1987-02-05 1990-04-03 The Adminstrators Of The Tulane Educational Fund Synthetic GHRH analogs
WO1993001152A2 (en) * 1991-07-03 1993-01-21 E.I. Du Pont De Nemours And Company Azeotropic or azeotrope-like compositions of pentafluoroethane and propane or isobutane
US5498724A (en) * 1994-06-28 1996-03-12 Aktiebolaget Astra Pyrazoleamidine compounds

Also Published As

Publication number Publication date
WO1994029269A1 (en) 1994-12-22
BR9406713A (pt) 1996-03-19
NO954835D0 (no) 1995-11-28
AU674970B2 (en) 1997-01-16
SK151895A3 (en) 1996-04-03
HUT74293A (en) 1996-11-28
IL109683A0 (en) 1994-08-26
GR3030501T3 (en) 1999-10-29
SE9301912D0 (sv) 1993-06-03
HRP940317A2 (en) 1996-10-31
FI955800A (fi) 1995-12-01
EE9400348A (et) 1996-04-15
YU33594A (sh) 1997-05-28
EP0701550B1 (en) 1999-03-31
CZ320095A3 (en) 1996-07-17
CA2162920A1 (en) 1994-12-22
CN1124956A (zh) 1996-06-19
LTIP1940A (en) 1994-12-27
EP0701550A1 (en) 1996-03-20
LT3309B (en) 1995-06-26
ES2131688T3 (es) 1999-08-01
CA2162920C (en) 2005-08-09
NO954835L (no) 1995-11-28
DE69417554D1 (de) 1999-05-06
NZ267192A (en) 1997-03-24
US5659071A (en) 1997-08-19
JPH08511016A (ja) 1996-11-19
PL311760A1 (en) 1996-03-18
HU9503444D0 (en) 1996-01-29
NO305514B1 (no) 1999-06-14
FI955800A0 (fi) 1995-12-01
ATE178316T1 (de) 1999-04-15
JP3662925B2 (ja) 2005-06-22
FI120093B (fi) 2009-06-30
IS4165A (is) 1994-12-04
AU6940494A (en) 1995-01-03
DE69417554T2 (de) 1999-09-02

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