DE69627184D1 - 3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaften - Google Patents
3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaftenInfo
- Publication number
- DE69627184D1 DE69627184D1 DE69627184T DE69627184T DE69627184D1 DE 69627184 D1 DE69627184 D1 DE 69627184D1 DE 69627184 T DE69627184 T DE 69627184T DE 69627184 T DE69627184 T DE 69627184T DE 69627184 D1 DE69627184 D1 DE 69627184D1
- Authority
- DE
- Germany
- Prior art keywords
- dihydropyrrol
- amidino
- aminoethyl
- arginine
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YDRVFCVPWICTOV-UHFFFAOYSA-N 3-(2-aminoethyl)-2,5-dihydropyrrole-1-carboximidamide Chemical class NCCC1=CCN(C(N)=N)C1 YDRVFCVPWICTOV-UHFFFAOYSA-N 0.000 title 1
- MJSQLVQCYKAPNT-UHFFFAOYSA-N 2,3-dihydropyrrole-1-carboximidamide Chemical class NC(=N)N1CCC=C1 MJSQLVQCYKAPNT-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19546018 | 1995-12-09 | ||
DE19614179 | 1996-04-11 | ||
PCT/EP1996/005494 WO1997021725A1 (en) | 1995-12-09 | 1996-12-09 | 3-aminoethyl-n-amidino-2,5-dihydropyrrole derivatives having arginine mimetic properties |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69627184D1 true DE69627184D1 (de) | 2003-05-08 |
Family
ID=26021108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69627184T Expired - Lifetime DE69627184D1 (de) | 1995-12-09 | 1996-12-09 | 3-aminoethyl-n-amidino-2,5-dihydropyrrol derivative mit arginine-mimetischen eigenschaften |
Country Status (9)
Country | Link |
---|---|
US (1) | US20020026034A1 (de) |
EP (1) | EP0865445B1 (de) |
JP (1) | JP2000502078A (de) |
AT (1) | ATE236192T1 (de) |
AU (1) | AU1192097A (de) |
CA (1) | CA2239908A1 (de) |
DE (1) | DE69627184D1 (de) |
TW (1) | TW455580B (de) |
WO (1) | WO1997021725A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0902036A1 (de) | 1997-09-05 | 1999-03-17 | Roche Diagnostics GmbH | Peptide mit einem Arginine-Substitut für die Behandlung von Osteoporosis, deren Herstellung und diese enthaltende Verbindungen |
US6403818B1 (en) | 2000-02-28 | 2002-06-11 | Eisai Co., Ltd. | Process for producing α-hydroxy-carbonyl compound |
CN117164932B (zh) * | 2023-10-31 | 2024-01-26 | 汕头市虹桥包装实业有限公司 | 一种注塑发泡聚丙烯材料及其制备方法和在轻量化高性能瓶盖中的应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9301912D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | Process for the production of aminoalkylguandines |
SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
-
1996
- 1996-12-09 DE DE69627184T patent/DE69627184D1/de not_active Expired - Lifetime
- 1996-12-09 JP JP09521726A patent/JP2000502078A/ja active Pending
- 1996-12-09 AT AT96943062T patent/ATE236192T1/de not_active IP Right Cessation
- 1996-12-09 WO PCT/EP1996/005494 patent/WO1997021725A1/en active IP Right Grant
- 1996-12-09 US US09/077,879 patent/US20020026034A1/en not_active Abandoned
- 1996-12-09 TW TW085115198A patent/TW455580B/zh not_active IP Right Cessation
- 1996-12-09 EP EP96943062A patent/EP0865445B1/de not_active Expired - Lifetime
- 1996-12-09 AU AU11920/97A patent/AU1192097A/en not_active Abandoned
- 1996-12-09 CA CA002239908A patent/CA2239908A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2000502078A (ja) | 2000-02-22 |
WO1997021725A1 (en) | 1997-06-19 |
EP0865445B1 (de) | 2003-04-02 |
TW455580B (en) | 2001-09-21 |
US20020026034A1 (en) | 2002-02-28 |
AU1192097A (en) | 1997-07-03 |
EP0865445A1 (de) | 1998-09-23 |
CA2239908A1 (en) | 1997-06-19 |
ATE236192T1 (de) | 2003-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |