HUP9800688A2 - Gamma-ciklodextrin és retinol, ill. retinolszármazékok komplexei, eljárás ezek előállítására és ezeket tartalmazó kozmetikai és gyógyszerkészítmények - Google Patents

Gamma-ciklodextrin és retinol, ill. retinolszármazékok komplexei, eljárás ezek előállítására és ezeket tartalmazó kozmetikai és gyógyszerkészítmények

Info

Publication number
HUP9800688A2
HUP9800688A2 HU9800688A HUP9800688A HUP9800688A2 HU P9800688 A2 HUP9800688 A2 HU P9800688A2 HU 9800688 A HU9800688 A HU 9800688A HU P9800688 A HUP9800688 A HU P9800688A HU P9800688 A2 HUP9800688 A2 HU P9800688A2
Authority
HU
Hungary
Prior art keywords
retinol
cyclodextrin
production
cosmetic
gamma
Prior art date
Application number
HU9800688A
Other languages
English (en)
Inventor
Jens-Peter Moldenhauer
Marlies Regiert
Thomas Wimmer
Original Assignee
Wacker-Chemie Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wacker-Chemie Gmbh. filed Critical Wacker-Chemie Gmbh.
Publication of HUP9800688A2 publication Critical patent/HUP9800688A2/hu
Publication of HUP9800688A3 publication Critical patent/HUP9800688A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/12—Face or body powders for grooming, adorning or absorbing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgyát g-ciklődextrin és retinől, illetveretinőlszármazékők kőmplexei képezik, valamint eljárás e kőmplexekelőállítására és e kőmplexeket tartalmazó gyógyszer, illetvekőzmetikai készítmények. ŕ
HU9800688A 1997-03-27 1998-03-27 Complex of gamma-cyclodextrin and retinol or retinol derivatives, process for their production and cosmetic an pharmaceutical compositions containing them HUP9800688A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19713092A DE19713092A1 (de) 1997-03-27 1997-03-27 Komplexe aus Gamma-Cyclodextrin und Retinol bzw. Retinol-Derivaten sowie Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (2)

Publication Number Publication Date
HUP9800688A2 true HUP9800688A2 (hu) 1999-02-01
HUP9800688A3 HUP9800688A3 (en) 1999-04-28

Family

ID=7824924

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800688A HUP9800688A3 (en) 1997-03-27 1998-03-27 Complex of gamma-cyclodextrin and retinol or retinol derivatives, process for their production and cosmetic an pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US5985296A (hu)
EP (1) EP0867175B1 (hu)
JP (1) JP3010435B2 (hu)
KR (1) KR100304382B1 (hu)
CA (1) CA2233108C (hu)
DE (2) DE19713092A1 (hu)
HU (1) HUP9800688A3 (hu)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602513B2 (en) * 1997-11-27 2003-08-05 Shiseido Co., Ltd. Face pack
DE19847633C1 (de) * 1998-10-15 2000-03-02 Wacker Chemie Gmbh Verfahren zur Komplexierung von Retinol mit gamma-Cyclodextrin
DE19943678A1 (de) * 1999-09-13 2001-03-15 Beiersdorf Ag Wirkstoffkombinationen aus oberflächenaktiven Citronensäureestern und Einschlußverbindungen von Cyclodextrinen und Retinoiden sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
WO2002000183A2 (en) * 2000-06-26 2002-01-03 The Regents Of The University Of Michigan Use of egf-r protein tyrosine kinase inhibitors for preventing photoaging in human skin
KR100402576B1 (ko) * 2000-07-05 2003-10-22 동아제약 주식회사 레티놀을 다중 안정화시켜 함유하는 화장료
IT1317911B1 (it) * 2000-09-28 2003-07-15 Idi Irccs Formulazione cosmetica.
KR100437102B1 (ko) * 2001-01-11 2004-06-23 (주)케비젠 신규한 레티놀 유도체, 그 제조방법 및 그 용도
AU2002255627B2 (en) * 2001-02-27 2008-01-17 The Regents Of The University Of Michigan Use of natural EGFR inhibitors to prevent side effects due to retinoid therapy, soaps, and other stimuli that activate the epidermal growth receptor
DE10141682A1 (de) * 2001-08-25 2003-03-06 Beiersdorf Ag Verwendung von Cyclodextrinen zur Herstellung kosmetischer und dermatologischer Zubereitungen mit verbesserter Verteilbarkeit von Füllstoffen auf der Haut sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an Cyclodextrinen und Füllstoffen
DE10151245A1 (de) * 2001-10-17 2003-05-15 Beiersdorf Ag Kosmetische und/oder dermatologische Wirkstoffkombination
EP1304161B1 (en) * 2001-10-19 2007-02-28 Pacific Corporation Thermotropic liquid crystal polymer microcapsules, a method for preparing the same, and cosmetic compositions containing the same
JP4528903B2 (ja) * 2002-03-11 2010-08-25 石川県 植物含有有効成分のサイクロデキストリン包接物の製造方法
DE10224298A1 (de) * 2002-05-31 2003-12-18 Beiersdorf Ag Kosmetische Stoffkombinationen
US20030232091A1 (en) * 2002-06-17 2003-12-18 Adi Shefer Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof
FI20030426A (fi) * 2003-03-24 2004-09-25 Tomi Jaervinen Syklodekstriinikompleksit
US20060177405A1 (en) * 2005-02-04 2006-08-10 Morrissey Maureen S Moisturizing compositions
MX2007015871A (es) * 2005-06-13 2008-03-04 Cargill Inc Complejos de inclusion de ciclodextrina y metodos para preparar los mismos.
BRPI0611925A2 (pt) * 2005-06-13 2010-10-13 Cargill Inc complexos de inclusão de ciclodextrina e métodos de preparação dos mesmos
CN101431980B (zh) * 2006-05-02 2012-08-01 株式会社东洋发酵 发酵物组合物、化妆品组合物和它们的制造方法
JP2009539978A (ja) * 2006-06-13 2009-11-19 カーギル インコーポレイテッド 大粒子シクロデキストリン包接複合体及びその製造方法
WO2008035682A1 (fr) * 2006-09-22 2008-03-27 Kurabe Industrial Co., Ltd. Corps poreux à base de ptfe, mélange de ptfe, procédé de production de corps poreux à base de ptfe, et fil/câble électrique utilisant le corps poreux à base de ptfe
WO2008083213A2 (en) * 2006-12-27 2008-07-10 Cargill, Incorporated Stabilisation by preparing cyclodextrin inclusion complexes
US20080283693A1 (en) * 2007-05-15 2008-11-20 Evans Michael J F Propulsion apparatus and system
DE102007051614A1 (de) * 2007-10-24 2009-04-30 Coty Prestige Lancaster Group Gmbh Retinolhaltiges Kosmetikprodukt
DE102008022041A1 (de) * 2008-04-29 2009-11-05 Coty Prestige Lancaster Group Gmbh Kosmetisches Erzeugnis mit verzögerter Retinolfreisetzung
US8410079B2 (en) 2010-08-06 2013-04-02 Island Kinetics Chirally correct retinal cyclodextrin hemiacetals for clarifying skin complexion
WO2013142251A1 (en) * 2012-03-22 2013-09-26 Precision Dermatology, Inc. Cyclodextrin-based microemulsions, and dermatological uses thereof
US20140094433A1 (en) * 2012-10-02 2014-04-03 Allergan, Inc. Dermal filler hydrogels with vitamin a/cyclodextrin inclusion complexes
US10117823B2 (en) 2013-03-12 2018-11-06 Primal Therapies, Inc. Dental composition comprising chelator and base
KR101503301B1 (ko) * 2013-07-22 2015-03-17 주식회사 웰코스 레티닐팔미테이트 안정화 조성물
EP3290026A1 (en) 2016-09-06 2018-03-07 Athenion AG Method for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents
EP3421096A1 (en) 2017-06-30 2019-01-02 Athenion AG Method for solubilizing poorly water-soluble cosmetic agents
WO2019150087A1 (en) * 2018-01-30 2019-08-08 Olusola Clement Idowu Mangiferin as a protective agent against mitochondrial dna damage and skin-care compositions comprising same
CN112294693B (zh) * 2019-07-26 2021-07-20 珀莱雅化妆品股份有限公司 一种视黄醇及其衍生物的超分子制剂及其制备方法
CN110623859A (zh) * 2019-10-25 2019-12-31 广州市博之越精细化工有限公司 一种羟丙基环糊精包合视黄醇的制备方法
KR102297632B1 (ko) * 2021-04-19 2021-09-06 주식회사 라파스 레티놀 안정화를 위한 사이클로덱스트린을 포함하는 마이크로니들 제조용 조성물 및 이러한 조성물로 제조된 마이크로니들
CN113181078A (zh) * 2021-05-21 2021-07-30 何平蓉 一种滋润收敛型深层清洁面膜粉
CN113244157A (zh) * 2021-06-04 2021-08-13 何平蓉 一种防暗沉持妆粉饼及其制备方法
CN113318027A (zh) * 2021-06-15 2021-08-31 何平蓉 一种温和型控油祛痘洁面组合物及其制备方法
CN114869797B (zh) * 2022-03-22 2023-07-21 深圳市美莲达生物科技有限公司 含有视黄醇和黄精多糖的精华液及其应用
CN114652659B (zh) * 2022-05-10 2023-07-14 广州兰蝶生物科技有限公司 一种含芦荟和玫瑰纯露的保湿凝胶
CN115381732B (zh) * 2022-08-01 2023-05-12 广州市博之越精细化工有限公司 一种羟丙基环糊精包合视黄醇的制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2827452A (en) * 1955-05-31 1958-03-18 Univ Minnesota Stabilization of materials
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
DE68906942T3 (de) * 1988-03-29 1999-05-12 Univ Florida Pharmazeutische Zusammensetzungen für die parenterale Anwendung.
JP2779424B2 (ja) * 1988-10-19 1998-07-23 日清製粉株式会社 α−トコフエロールビタミンＡ酸エステル−シクロデキストリン複合体
FR2647015B1 (fr) * 1989-05-17 1994-05-06 Cird Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique
ATE100712T1 (de) * 1989-05-24 1994-02-15 Innovet Inc Hypoallergene anaesthesierende/hypnotische steroide arzneizubereitung.
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
CA2013485C (en) * 1990-03-06 1997-04-22 John Michael Gardlik Solid consumer product compositions containing small particle cyclodextrin complexes
ES2289370T3 (es) * 1992-07-13 2008-02-01 Shiseido Company, Ltd. Composicion estabilizada para tratamiento cutaneo externo que comprende retinol.
US5324718A (en) * 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
US5472954A (en) * 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
SE9300971D0 (sv) * 1993-03-24 1993-03-24 Jan Wadstein Hudvaardskomposition
DE69425948T2 (de) * 1993-12-06 2001-02-22 Takeda Chemical Industries Ltd Zusammensetzung mit verbesserter Wasserlöslichkeit, enthaltend eine Wasserunlösliche oder an Wasser schwerunlösliche Verbindung

Also Published As

Publication number Publication date
JPH10279504A (ja) 1998-10-20
CA2233108A1 (en) 1998-09-27
DE59800221D1 (de) 2000-09-14
EP0867175B1 (de) 2000-08-09
KR100304382B1 (ko) 2002-04-24
US5985296A (en) 1999-11-16
EP0867175A1 (de) 1998-09-30
DE19713092A1 (de) 1998-10-01
HUP9800688A3 (en) 1999-04-28
CA2233108C (en) 2005-07-26
KR19980080135A (ko) 1998-11-25
JP3010435B2 (ja) 2000-02-21

Similar Documents

Publication Publication Date Title
HUP9800688A2 (hu) Gamma-ciklodextrin és retinol, ill. retinolszármazékok komplexei, eljárás ezek előállítására és ezeket tartalmazó kozmetikai és gyógyszerkészítmények
SE9704545D0 (sv) Novel compounds
SE9704544D0 (sv) Novel compounds
MY123193A (en) Novel 2-(iminomethyl)amino-phenyl derivatives,preparation,application as medicines and compositions containing same
DE69715888T2 (de) Pyridylalken- und pyridylalkin-säureamide als cytostatika und immunosuppressive arzneimittel
SE9904505D0 (sv) Novel compounds
ZA965752B (en) Triphenylethylenes, process for their production, pharmaceutical preparations that contain these triphenylethylenes as well as their use for the production of pharmaceutical agents.
DE69807741D1 (de) Neuartige verbindungen
TR200200768T2 (tr) Yeni kuinüklidin türevleri ve bunu içeren ilaç bileşimleri
HK1047575A1 (en) Indanyl-substituted benzole carbonamide, method for the production of the same, use thereof as a medicament and pharmaceutical preparations containingthe same.
DK0960107T3 (da) 6-Thiosubstituerede paclitaxeler
SE9704546D0 (sv) Novel compounds
MY124146A (en) Novel 2-(iminomethyl) amino-phenyl derivatives, preparation, application as medicines and pharmaceutical compositions containing same
NO930059L (no) O-glykosylert ifn-alfa
NO306725B1 (no) Ny krystallmodifikasjon av CDCH, fremgangsmate for fremstilling derav og farmasoytiske preparater inneholdende denne samt anvendelse av forbindelsen for fremstilling av legemidler
FI980862A0 (fi) Kiraalisia metyylifenyylioksatsolidinoneja
HUP0300755A2 (hu) Heparinszármazék poliszacharid keverékek, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
NO972391D0 (no) 2-substituerte 1,2,5-tiadiazolidin-3-on 1,1-dioksider og preparater og metoder for anvendelse derav
ES2144239T3 (es) Derivados de vitamina d con sustituyentes en c-25, procedimiento para su preparacion, productos intermedios y la utilizacion para la preparacion de medicamentos.
HUP9700826A1 (hu) Peptikus fekély elleni gyógyászati készítmények
AU2924699A (en) Tryptase inhibitors
ATE297750T1 (de) Verwendung von hsp70 protein
HUP9903935A2 (hu) D-vitamin analógokat tartalmazó gyógyszerkészítmények
ES2191449T3 (es) Derivados de ciclopentabenzofurano y su uso.
HUP0200055A2 (hu) 16-Hidroxi-ösztratriének és ezeket tartalmazó gyógyszerkészítmények

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: WACKER CHEMIE AG, DE

Free format text: FORMER OWNER(S): WACKER-CHEMIE GMBH., DE

FD9A Lapse of provisional protection due to non-payment of fees