YU33001A - Postupak za proizvodnju kapsula punjenih tečnim supstancama - Google Patents

Postupak za proizvodnju kapsula punjenih tečnim supstancama

Info

Publication number
YU33001A
YU33001A YU33001A YU33001A YU33001A YU 33001 A YU33001 A YU 33001A YU 33001 A YU33001 A YU 33001A YU 33001 A YU33001 A YU 33001A YU 33001 A YU33001 A YU 33001A
Authority
YU
Yugoslavia
Prior art keywords
capsules
active agent
manufacture
process according
reduced
Prior art date
Application number
YU33001A
Other languages
English (en)
Inventor
Rainer Alex
Jurgen Gerhards
Ingeborg Kraemer-Pittrof
Richard Oeschger
Thomass Rades
Original Assignee
F. Hoffmann-La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag. filed Critical F. Hoffmann-La Roche Ag.
Publication of YU33001A publication Critical patent/YU33001A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072—Sealing capsules, e.g. rendering them tamper-proof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074—Filling capsules; Related operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Basic Packing Technique (AREA)
  • Confectionery (AREA)

Abstract

Ovaj pronalazak se odnosi na postupak za enkapsuliranje na smicanje osetljive punjačke mase u kapsule, okarakterisan time što se navedena punjačka masa zagreva i potom hladi, odmah pre enkapsuliranja. Pronalazak se takodje odnosi na kapsule koje se mogu dobiti navedenim postupkom. Postupak prema ovom pronalasku omogućava dobijanje kapsula koje pokazuju visoke i konstantne stepene rastvortjivosti. Količina unosa aktivnog sredstva može time biti smanjena pošto se samo aktivno sredstvo brzo rastvara. Ukupna cena leka je time takodje smanjena. Visoka homogenost (a time i visok i konstantan stepen rastvaranjal kapsula proizvedenih u procesu u skladu sa ovim pronalaskom garantuje ponovljivu bioupotrebljivost i terapeutski efekat aktivnosg sredstva koje je sadržano u njoj.
YU33001A 1998-11-17 1999-11-11 Postupak za proizvodnju kapsula punjenih tečnim supstancama YU33001A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98121831 1998-11-17

Publications (1)

Publication Number Publication Date
YU33001A true YU33001A (sh) 2004-05-12

Family

ID=8232985

Family Applications (1)

Application Number Title Priority Date Filing Date
YU33001A YU33001A (sh) 1998-11-17 1999-11-11 Postupak za proizvodnju kapsula punjenih tečnim supstancama

Country Status (35)

Country Link
US (1) US6352717B2 (sh)
EP (1) EP1131037B1 (sh)
JP (1) JP3623166B2 (sh)
KR (1) KR100446118B1 (sh)
CN (1) CN1172649C (sh)
AR (1) AR020013A1 (sh)
AT (1) ATE274895T1 (sh)
AU (1) AU751446B2 (sh)
BR (1) BR9915444B1 (sh)
CA (1) CA2350943C (sh)
CO (1) CO5150161A1 (sh)
CZ (1) CZ299800B6 (sh)
DE (1) DE69919889T2 (sh)
DK (1) DK1131037T3 (sh)
ES (1) ES2228141T3 (sh)
HK (1) HK1042227B (sh)
HR (1) HRP20010341A2 (sh)
HU (1) HU226498B1 (sh)
ID (1) ID30128A (sh)
IL (2) IL143119A0 (sh)
MA (1) MA26761A1 (sh)
MY (1) MY120081A (sh)
NO (1) NO20012384L (sh)
NZ (1) NZ511663A (sh)
PE (1) PE20001240A1 (sh)
PL (1) PL190382B1 (sh)
PT (1) PT1131037E (sh)
RU (1) RU2219911C2 (sh)
SI (1) SI1131037T1 (sh)
TR (1) TR200101358T2 (sh)
TW (1) TWI221767B (sh)
UY (1) UY25803A1 (sh)
WO (1) WO2000028942A1 (sh)
YU (1) YU33001A (sh)
ZA (1) ZA200103891B (sh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE292453T1 (de) * 1999-12-09 2005-04-15 Alza Corp Antivirale arznei
GB0027954D0 (en) * 2000-11-16 2001-01-03 Mw Encap Ltd Liquid filled capsules
ES2257998T3 (es) * 2000-12-20 2006-08-16 Swiss Caps Rechte Und Lizenzen Ag Procedimiento de troquelado rotatorio y cuña de llenado para fabricar capsulas, en especial capsulas blandas.
US7247010B2 (en) 2003-10-01 2007-07-24 Technophar Equipment & Service Limited Servo control for capsule making machine
GB0712972D0 (en) * 2007-07-04 2007-08-15 Glaxosmithkline Consumer Healt Formulation
EP2042180A1 (de) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Phytosterol-haltige Präparate
CL2010000098A1 (es) * 2009-02-04 2011-01-21 Kalamazoo Holdings Inc Composicion antioxidante de extracto de hierbas comestibles, especies, frutas y/o verduras; metodos para estabilizar diferentes alimentos que comprende incorporar el antioxidante que se obtiene por extraccion con solvente polar hierbas comestibles, especias y/o frutas previamente desgrasadas por extraccion con solvente no polar.
EP2410970B1 (de) * 2009-03-26 2013-02-13 Swiss Caps Rechte und Lizenzen AG Verfahren und vorrichtung zur herstellung von weichkapseln
WO2013031972A1 (ja) * 2011-09-02 2013-03-07 株式会社三協 カプセル製造装置における内包液の供給用ポンプユニット 並びにこのポンプユニットを適用したカプセル剤の製造装置並びに製造方法 並びにこれによって製造されるカプセル剤
US10568811B2 (en) * 2016-02-22 2020-02-25 R.P. Scherer Technologies, Llc Multiple-fluid injection pump
CN109645530A (zh) * 2019-01-09 2019-04-19 安徽亳药千草国药股份有限公司 一种用于灌注富硒灵芝孢子油的软胶囊机

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2692404A (en) * 1949-12-07 1954-10-26 Gennell Capsulations Inc Method and apparatus for forming capsules
JPS56163656A (en) * 1980-05-22 1981-12-16 Nippon Elanco Device for filling hard gelatin capsule with viscous substance
US4656066A (en) * 1982-12-20 1987-04-07 Warner-Lambert Company Apparatus and method for sealing capsules
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4609403A (en) * 1984-03-12 1986-09-02 Warner-Lambert Company Foam soft gelatin capsules and their method of manufacture
DE8536337U1 (de) * 1985-12-23 1986-02-13 R.P. Scherer GmbH, 6930 Eberbach Füllkeil für eine Maschine zum Herstellen von Gelatinekapseln
FI80828C (fi) * 1988-04-08 1990-08-10 Piscina Oy Anordning foer vaermning av en vattenbaedd.
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
SI0649651T1 (en) * 1993-09-28 2001-02-28 Scherer Gmbh R P Soft gelatin capsule manufacture
GB9403449D0 (en) * 1994-02-23 1994-04-13 Wellcome Found Therapeutic benzonitriles
KR960016371U (ko) * 1994-11-11 1996-06-17 김덕흥 소프트젤라틴 캡슐제조기의 젤라틴시트 냉각장치

Also Published As

Publication number Publication date
WO2000028942A1 (en) 2000-05-25
CN1326335A (zh) 2001-12-12
PE20001240A1 (es) 2000-11-14
ATE274895T1 (de) 2004-09-15
JP2002529200A (ja) 2002-09-10
CN1172649C (zh) 2004-10-27
BR9915444A (pt) 2001-08-07
NO20012384D0 (no) 2001-05-15
NZ511663A (en) 2003-08-29
AU751446B2 (en) 2002-08-15
RU2219911C2 (ru) 2003-12-27
KR100446118B1 (ko) 2004-08-30
IL143119A0 (en) 2002-04-21
KR20010075711A (ko) 2001-08-09
PL348350A1 (en) 2002-05-20
DE69919889T2 (de) 2005-09-15
SI1131037T1 (en) 2004-12-31
HUP0104464A2 (hu) 2002-03-28
HK1042227A1 (en) 2002-08-09
DE69919889D1 (de) 2004-10-07
UY25803A1 (es) 2000-08-21
MA26761A1 (fr) 2004-12-20
US6352717B2 (en) 2002-03-05
TWI221767B (en) 2004-10-11
AR020013A1 (es) 2002-03-27
ZA200103891B (en) 2002-08-14
HK1042227B (zh) 2005-03-18
CO5150161A1 (es) 2002-04-29
HRP20010341A2 (en) 2002-06-30
DK1131037T3 (da) 2005-01-10
ID30128A (id) 2001-11-08
CA2350943A1 (en) 2000-05-25
PT1131037E (pt) 2004-12-31
IL143119A (en) 2007-05-15
HU226498B1 (en) 2009-03-02
ES2228141T3 (es) 2005-04-01
CZ299800B6 (cs) 2008-11-26
EP1131037A1 (en) 2001-09-12
BR9915444B1 (pt) 2013-10-22
TR200101358T2 (tr) 2001-12-21
JP3623166B2 (ja) 2005-02-23
US20020006417A1 (en) 2002-01-17
CZ20011644A3 (cs) 2001-08-15
MY120081A (en) 2005-08-30
HUP0104464A3 (en) 2006-06-28
PL190382B1 (pl) 2005-12-30
AU1775100A (en) 2000-06-05
CA2350943C (en) 2006-06-20
NO20012384L (no) 2001-05-15
EP1131037B1 (en) 2004-09-01

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