ATE274895T1 - Verfahren zur herstellung von flüssigkeitsgefüllten kapseln - Google Patents

Verfahren zur herstellung von flüssigkeitsgefüllten kapseln

Info

Publication number
ATE274895T1
ATE274895T1 AT99960972T AT99960972T ATE274895T1 AT E274895 T1 ATE274895 T1 AT E274895T1 AT 99960972 T AT99960972 T AT 99960972T AT 99960972 T AT99960972 T AT 99960972T AT E274895 T1 ATE274895 T1 AT E274895T1
Authority
AT
Austria
Prior art keywords
filled capsules
producing liquid
capsules
filled
producing
Prior art date
Application number
AT99960972T
Other languages
English (en)
Inventor
Rainer Alex
Juergen Gerhards
Ingeborg Kraemer-Pittrof
Richard Oeschger
Thomas Rades
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE274895T1 publication Critical patent/ATE274895T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833Encapsulating processes; Filling of capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/072Sealing capsules, e.g. rendering them tamper-proof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A61J3/071Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
    • A61J3/074Filling capsules; Related operations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Basic Packing Technique (AREA)
  • Confectionery (AREA)
  • Medicines Containing Plant Substances (AREA)
AT99960972T 1998-11-17 1999-11-11 Verfahren zur herstellung von flüssigkeitsgefüllten kapseln ATE274895T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98121831 1998-11-17
PCT/EP1999/008684 WO2000028942A1 (en) 1998-11-17 1999-11-11 Process for the manufacture of liquid filled capsules

Publications (1)

Publication Number Publication Date
ATE274895T1 true ATE274895T1 (de) 2004-09-15

Family

ID=8232985

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960972T ATE274895T1 (de) 1998-11-17 1999-11-11 Verfahren zur herstellung von flüssigkeitsgefüllten kapseln

Country Status (35)

Country Link
US (1) US6352717B2 (de)
EP (1) EP1131037B1 (de)
JP (1) JP3623166B2 (de)
KR (1) KR100446118B1 (de)
CN (1) CN1172649C (de)
AR (1) AR020013A1 (de)
AT (1) ATE274895T1 (de)
AU (1) AU751446B2 (de)
BR (1) BR9915444B1 (de)
CA (1) CA2350943C (de)
CO (1) CO5150161A1 (de)
CZ (1) CZ299800B6 (de)
DE (1) DE69919889T2 (de)
DK (1) DK1131037T3 (de)
ES (1) ES2228141T3 (de)
HK (1) HK1042227B (de)
HR (1) HRP20010341A2 (de)
HU (1) HU226498B1 (de)
ID (1) ID30128A (de)
IL (2) IL143119A0 (de)
MA (1) MA26761A1 (de)
MY (1) MY120081A (de)
NO (1) NO20012384L (de)
NZ (1) NZ511663A (de)
PE (1) PE20001240A1 (de)
PL (1) PL190382B1 (de)
PT (1) PT1131037E (de)
RU (1) RU2219911C2 (de)
SI (1) SI1131037T1 (de)
TR (1) TR200101358T2 (de)
TW (1) TWI221767B (de)
UY (1) UY25803A1 (de)
WO (1) WO2000028942A1 (de)
YU (1) YU33001A (de)
ZA (1) ZA200103891B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60019334T2 (de) * 1999-12-09 2005-09-08 Alza Corp., Mountain View Antivirale arznei
GB0027954D0 (en) * 2000-11-16 2001-01-03 Mw Encap Ltd Liquid filled capsules
EP1216680B1 (de) * 2000-12-20 2006-03-15 Swiss Caps Rechte und Lizenzen AG Rotary-Die-Verfahren und Füllkeil zum Herstellen von Kapseln, insbesondere Weichkapseln
US7247010B2 (en) 2003-10-01 2007-07-24 Technophar Equipment & Service Limited Servo control for capsule making machine
GB0712972D0 (en) * 2007-07-04 2007-08-15 Glaxosmithkline Consumer Healt Formulation
EP2042180A1 (de) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Phytosterol-haltige Präparate
WO2010090741A1 (en) * 2009-02-04 2010-08-12 Kalamazoo Holdings, Inc. Compositions and methods for enhancing the stability of foods, beverages, nutritional supplements and cosmetics
PL2410970T3 (pl) * 2009-03-26 2013-07-31 Swiss Caps Rechte Und Lizenzen Ag Sposób i urządzenie do wytwarzania kapsułek miękkich
JP6106592B2 (ja) * 2011-09-02 2017-04-05 株式会社三協 カプセル製造装置における内包液の供給用ポンプユニット 並びにこのポンプユニットを適用したカプセル剤の製造装置並びに製造方法 並びにこれによって製造されるカプセル剤
US10568811B2 (en) * 2016-02-22 2020-02-25 R.P. Scherer Technologies, Llc Multiple-fluid injection pump
CN109645530A (zh) * 2019-01-09 2019-04-19 安徽亳药千草国药股份有限公司 一种用于灌注富硒灵芝孢子油的软胶囊机

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2692404A (en) * 1949-12-07 1954-10-26 Gennell Capsulations Inc Method and apparatus for forming capsules
JPS56163656A (en) * 1980-05-22 1981-12-16 Nippon Elanco Device for filling hard gelatin capsule with viscous substance
US4656066A (en) * 1982-12-20 1987-04-07 Warner-Lambert Company Apparatus and method for sealing capsules
JPS59131355A (ja) * 1983-01-17 1984-07-28 森下仁丹株式会社 多重軟カプセルの製法
US4609403A (en) * 1984-03-12 1986-09-02 Warner-Lambert Company Foam soft gelatin capsules and their method of manufacture
DE8536337U1 (de) * 1985-12-23 1986-02-13 R.P. Scherer GmbH, 6930 Eberbach Füllkeil für eine Maschine zum Herstellen von Gelatinekapseln
FI80828C (fi) * 1988-04-08 1990-08-10 Piscina Oy Anordning foer vaermning av en vattenbaedd.
IL110752A (en) * 1993-09-13 2000-07-26 Abbott Lab Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
ES2308955T5 (es) * 1993-09-28 2012-04-03 R.P. Scherer Gmbh Fabricación de cápsulas de gelatina blanda
GB9403449D0 (en) * 1994-02-23 1994-04-13 Wellcome Found Therapeutic benzonitriles
KR960016371U (ko) * 1994-11-11 1996-06-17 김덕흥 소프트젤라틴 캡슐제조기의 젤라틴시트 냉각장치

Also Published As

Publication number Publication date
TR200101358T2 (tr) 2001-12-21
AR020013A1 (es) 2002-03-27
BR9915444A (pt) 2001-08-07
HK1042227A1 (en) 2002-08-09
CZ299800B6 (cs) 2008-11-26
ZA200103891B (en) 2002-08-14
AU751446B2 (en) 2002-08-15
CA2350943A1 (en) 2000-05-25
RU2219911C2 (ru) 2003-12-27
HRP20010341A2 (en) 2002-06-30
IL143119A0 (en) 2002-04-21
IL143119A (en) 2007-05-15
HUP0104464A2 (hu) 2002-03-28
CN1326335A (zh) 2001-12-12
NO20012384D0 (no) 2001-05-15
DK1131037T3 (da) 2005-01-10
CZ20011644A3 (cs) 2001-08-15
US6352717B2 (en) 2002-03-05
EP1131037A1 (de) 2001-09-12
SI1131037T1 (en) 2004-12-31
UY25803A1 (es) 2000-08-21
MY120081A (en) 2005-08-30
DE69919889T2 (de) 2005-09-15
US20020006417A1 (en) 2002-01-17
HU226498B1 (en) 2009-03-02
HUP0104464A3 (en) 2006-06-28
ES2228141T3 (es) 2005-04-01
JP2002529200A (ja) 2002-09-10
WO2000028942A1 (en) 2000-05-25
PL190382B1 (pl) 2005-12-30
AU1775100A (en) 2000-06-05
KR20010075711A (ko) 2001-08-09
KR100446118B1 (ko) 2004-08-30
TWI221767B (en) 2004-10-11
MA26761A1 (fr) 2004-12-20
CN1172649C (zh) 2004-10-27
NO20012384L (no) 2001-05-15
BR9915444B1 (pt) 2013-10-22
CO5150161A1 (es) 2002-04-29
DE69919889D1 (de) 2004-10-07
NZ511663A (en) 2003-08-29
EP1131037B1 (de) 2004-09-01
YU33001A (sh) 2004-05-12
CA2350943C (en) 2006-06-20
ID30128A (id) 2001-11-08
PL348350A1 (en) 2002-05-20
PT1131037E (pt) 2004-12-31
JP3623166B2 (ja) 2005-02-23
HK1042227B (zh) 2005-03-18
PE20001240A1 (es) 2000-11-14

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