YU31189A - 3'-deamino-4'-deoxy-4'-amino anthracyclins - Google Patents
3'-deamino-4'-deoxy-4'-amino anthracyclinsInfo
- Publication number
- YU31189A YU31189A YU00311/89A YU31189A YU31189A YU 31189 A YU31189 A YU 31189A YU 00311/89 A YU00311/89 A YU 00311/89A YU 31189 A YU31189 A YU 31189A YU 31189 A YU31189 A YU 31189A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- anthracyclins
- deamino
- deoxy
- amino
- hydrogen
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- -1 glycoside compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888803076A GB8803076D0 (en) | 1988-02-10 | 1988-02-10 | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU31189A true YU31189A (en) | 1991-02-28 |
Family
ID=10631459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU00311/89A YU31189A (en) | 1988-02-10 | 1989-02-09 | 3'-deamino-4'-deoxy-4'-amino anthracyclins |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4987126A (es) |
| EP (1) | EP0328400B1 (es) |
| JP (1) | JPH01294669A (es) |
| KR (1) | KR890013047A (es) |
| CN (1) | CN1037904A (es) |
| AT (1) | ATE88478T1 (es) |
| AU (1) | AU2974489A (es) |
| CA (1) | CA1338712C (es) |
| DE (1) | DE68906045T2 (es) |
| DK (1) | DK59289A (es) |
| ES (1) | ES2055035T3 (es) |
| FI (1) | FI890611A (es) |
| GB (1) | GB8803076D0 (es) |
| HU (1) | HUT49365A (es) |
| IL (1) | IL89199A0 (es) |
| NO (1) | NO890567L (es) |
| NZ (1) | NZ227877A (es) |
| PT (1) | PT89662B (es) |
| YU (1) | YU31189A (es) |
| ZA (1) | ZA891019B (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8818167D0 (en) * | 1988-07-29 | 1988-09-01 | Erba Carlo Spa | Novel 4-substituted anthracyclinones & process for their preparation |
| DE3842836A1 (de) * | 1988-12-20 | 1990-06-21 | Behringwerke Ag | Rhodomycine mit einer modifizierten kohlenhydrat-einheit |
| JP2779652B2 (ja) * | 1988-12-27 | 1998-07-23 | 武田薬品工業株式会社 | 生理活性物質ｔａｎ―１１２０，その還元体，それらの製造法および用途ならびに微生物 |
| GB8902709D0 (en) * | 1989-02-07 | 1989-03-30 | Erba Carlo Spa | New 4'-epi-4'-amino anthracyclines |
| US5412081A (en) * | 1989-02-07 | 1995-05-02 | Farmitalia Carlo Erba S.R.L. | New 4'-epi-4'-amino anthracyclines |
| IT1241927B (it) * | 1990-05-14 | 1994-02-01 | Menarini Farma Ind | 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono |
| GB9019934D0 (en) * | 1990-09-12 | 1990-10-24 | Erba Carlo Spa | 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines |
| GB9028105D0 (en) * | 1990-12-27 | 1991-02-13 | Erba Carlo Spa | Process for the preparation of substituted benzofuran derivatives |
| GB9216962D0 (en) * | 1992-08-11 | 1992-09-23 | Erba Carlo Spa | Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives |
| JPH0912590A (ja) * | 1995-06-23 | 1997-01-14 | Microbial Chem Res Found | ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−マンノピラノシル基を有する新規アンスラサイクリン誘導体 |
| JPH10175992A (ja) * | 1996-12-16 | 1998-06-30 | Microbial Chem Res Found | ４−アミノ−２，４，６−トリデオキシ−２−フルオロ−α−Ｌ−タロピラノシル基を有する新規アンスラサイクリン誘導体 |
| US5948896A (en) * | 1997-08-13 | 1999-09-07 | Gem Pharmaceuticals | Processes for preparing 13-deoxy anthracycline derivatives |
| US5942605A (en) * | 1998-03-03 | 1999-08-24 | Gem Pharmaceuticals, Inc. | 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them |
| US7381721B2 (en) * | 2003-03-17 | 2008-06-03 | Adolor Corporation | Substituted piperidine compounds |
| US6992090B2 (en) * | 2003-06-16 | 2006-01-31 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| US8946262B2 (en) * | 2003-12-04 | 2015-02-03 | Adolor Corporation | Methods of preventing and treating gastrointestinal dysfunction |
| US7087749B2 (en) * | 2004-03-11 | 2006-08-08 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| US20060063792A1 (en) * | 2004-09-17 | 2006-03-23 | Adolor Corporation | Substituted morphinans and methods of their use |
| US7538110B2 (en) * | 2005-10-27 | 2009-05-26 | Adolor Corporation | Opioid antagonists |
| JP2011512360A (ja) | 2008-02-14 | 2011-04-21 | アルカーメス，インコーポレイテッド | 選択的オピオイド化合物 |
| US20100311782A1 (en) | 2009-06-08 | 2010-12-09 | Adolor Corporation | Substituted piperidinylpropanoic acid compounds and methods of their use |
| CN102115483B (zh) * | 2009-12-30 | 2014-12-17 | 苏州天人合生物技术有限公司 | 卤代双去氧糖衍生物及其制备方法与应用 |
| CN105582094B (zh) * | 2016-03-11 | 2019-09-27 | 沈宁 | 一种治疗肾阴虚证的中药组合物及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1506200A (en) * | 1975-04-30 | 1978-04-05 | Farmaceutici Italia | Glycosides |
| GB1511559A (en) * | 1975-09-26 | 1978-05-24 | Farmaceutici Italia | Anthracycline glycosides |
| ATE8401T1 (de) * | 1980-11-01 | 1984-07-15 | Farmitalia Carlo Erba S.P.A. | Anthracyclin-glycoside, verfahren zu ihrer herstellung, zwischenprodukte und ihre herstellung und arzneimittel. |
| US4563444A (en) * | 1982-05-26 | 1986-01-07 | Farmitalia Carlo Erba S.P.A. | Anthracycline glycosides, use and compositions containing same |
-
1988
- 1988-02-10 GB GB888803076A patent/GB8803076D0/en active Pending
-
1989
- 1989-02-06 JP JP1027341A patent/JPH01294669A/ja active Pending
- 1989-02-07 IL IL89199A patent/IL89199A0/xx unknown
- 1989-02-07 NZ NZ227877A patent/NZ227877A/xx unknown
- 1989-02-08 AU AU29744/89A patent/AU2974489A/en not_active Abandoned
- 1989-02-09 CA CA000590535A patent/CA1338712C/en not_active Expired - Fee Related
- 1989-02-09 FI FI890611A patent/FI890611A/fi not_active Application Discontinuation
- 1989-02-09 PT PT89662A patent/PT89662B/pt active IP Right Grant
- 1989-02-09 YU YU00311/89A patent/YU31189A/xx unknown
- 1989-02-09 HU HU89605A patent/HUT49365A/hu unknown
- 1989-02-09 DK DK059289A patent/DK59289A/da not_active Application Discontinuation
- 1989-02-09 NO NO89890567A patent/NO890567L/no unknown
- 1989-02-09 ZA ZA891019A patent/ZA891019B/xx unknown
- 1989-02-10 KR KR1019890001513A patent/KR890013047A/ko not_active Application Discontinuation
- 1989-02-10 DE DE8989301283T patent/DE68906045T2/de not_active Expired - Fee Related
- 1989-02-10 US US07/308,449 patent/US4987126A/en not_active Expired - Fee Related
- 1989-02-10 CN CN89100739A patent/CN1037904A/zh active Pending
- 1989-02-10 EP EP89301283A patent/EP0328400B1/en not_active Expired - Lifetime
- 1989-02-10 ES ES89301283T patent/ES2055035T3/es not_active Expired - Lifetime
- 1989-02-10 AT AT89301283T patent/ATE88478T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| FI890611A (fi) | 1989-08-11 |
| IL89199A0 (en) | 1989-09-10 |
| GB8803076D0 (en) | 1988-03-09 |
| PT89662A (pt) | 1989-10-04 |
| US4987126A (en) | 1991-01-22 |
| JPH01294669A (ja) | 1989-11-28 |
| KR890013047A (ko) | 1989-09-21 |
| HUT49365A (en) | 1989-09-28 |
| DE68906045D1 (en) | 1993-05-27 |
| EP0328400A2 (en) | 1989-08-16 |
| NO890567L (no) | 1989-08-11 |
| ES2055035T3 (es) | 1994-08-16 |
| NZ227877A (en) | 1990-05-28 |
| EP0328400B1 (en) | 1993-04-21 |
| DK59289A (da) | 1989-08-11 |
| DK59289D0 (da) | 1989-02-09 |
| AU2974489A (en) | 1989-08-10 |
| DE68906045T2 (de) | 1993-08-05 |
| PT89662B (pt) | 1994-02-28 |
| FI890611A0 (fi) | 1989-02-09 |
| ATE88478T1 (de) | 1993-05-15 |
| ZA891019B (en) | 1989-10-25 |
| CA1338712C (en) | 1996-11-12 |
| NO890567D0 (no) | 1989-02-09 |
| EP0328400A3 (en) | 1989-11-08 |
| CN1037904A (zh) | 1989-12-13 |
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