YU217890A - Postupak za dobijanje genetskih konstrukcija za ekspresiju nervnog faktora rasta u eukariotskim ćelijama - Google Patents
Postupak za dobijanje genetskih konstrukcija za ekspresiju nervnog faktora rasta u eukariotskim ćelijamaInfo
- Publication number
- YU217890A YU217890A YU217890A YU217890A YU217890A YU 217890 A YU217890 A YU 217890A YU 217890 A YU217890 A YU 217890A YU 217890 A YU217890 A YU 217890A YU 217890 A YU217890 A YU 217890A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- growth factor
- procedure
- eukaryotic cells
- factor expression
- obtaining genetic
- Prior art date
Links
- 230000002068 genetic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003102 growth factor Substances 0.000 title 1
- 102100023995 Beta-nerve growth factor Human genes 0.000 abstract 2
- 101710129634 Beta-nerve growth factor Proteins 0.000 abstract 1
- 108010025020 Nerve Growth Factor Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940053128 nerve growth factor Drugs 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT04856489A IT1238348B (it) | 1989-11-16 | 1989-11-16 | Processo per la preparazione di costrutti genetici per l'espressione del fattore di crescita nervoso in cellule eucariote. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU217890A true YU217890A (sh) | 1993-05-28 |
Family
ID=11267348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU217890A YU217890A (sh) | 1989-11-16 | 1990-11-15 | Postupak za dobijanje genetskih konstrukcija za ekspresiju nervnog faktora rasta u eukariotskim ćelijama |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5457034A (enExample) |
| EP (1) | EP0432510B1 (enExample) |
| JP (2) | JP3121611B2 (enExample) |
| KR (1) | KR910009929A (enExample) |
| CN (1) | CN1051934A (enExample) |
| AR (1) | AR246983A1 (enExample) |
| AT (1) | ATE214735T1 (enExample) |
| CA (1) | CA2030108C (enExample) |
| DE (1) | DE69033937T2 (enExample) |
| ES (1) | ES2173856T3 (enExample) |
| FI (1) | FI905691L (enExample) |
| HU (1) | HUT61047A (enExample) |
| IE (1) | IE904120A1 (enExample) |
| IL (1) | IL96347A (enExample) |
| IT (1) | IT1238348B (enExample) |
| NZ (1) | NZ236058A (enExample) |
| PE (1) | PE28191A1 (enExample) |
| PL (1) | PL287811A1 (enExample) |
| PT (1) | PT95911B (enExample) |
| TW (1) | TW205069B (enExample) |
| YU (1) | YU217890A (enExample) |
| ZA (1) | ZA909122B (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5169762A (en) * | 1983-03-03 | 1992-12-08 | Genentech, Inc. | Human nerve growth factor by recombinant technology |
| US6090781A (en) * | 1996-11-06 | 2000-07-18 | Genentech, Inc. | Stabilizing formulation for NGF |
| US6964947B1 (en) | 1995-11-07 | 2005-11-15 | Genentech, Inc. | Stabilizing formulation for NGF |
| EP1123401A1 (en) * | 1998-10-22 | 2001-08-16 | The General Hospital Corporation | BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP) |
| EP2030986A1 (en) | 1999-09-29 | 2009-03-04 | The General Hospital Corporation | Polypeptide derivative of parathyroid hormone (PTH) |
| AU7734800A (en) * | 1999-09-29 | 2001-04-30 | General Hospital Corporation, The | Polypeptide derivatives of parathyroid hormone (pth) |
| ATE442041T1 (de) * | 2000-07-28 | 2009-09-15 | Murphy Christopher J | Medium für transplantat |
| JP4837888B2 (ja) * | 2001-07-23 | 2011-12-14 | ザ ジェネラル ホスピタル コーポレイション | コンホメーションが拘束された副甲状腺ホルモン（ｐｔｈ）類似体 |
| WO2004093902A1 (en) | 2003-03-19 | 2004-11-04 | The General Hospital Corporation | CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS |
| US7910544B2 (en) | 2003-07-17 | 2011-03-22 | The General Hospital Corporation | Conformationally constrained parthyroid hormone (PTH) analogs |
| US20070207209A1 (en) * | 2004-08-27 | 2007-09-06 | Murphy Christopher J | Trophic factor combinations for nervous system treatment |
| WO2008019062A2 (en) * | 2006-08-04 | 2008-02-14 | The General Hospital Corporation | Polypeptide derivatives of parathyroid hormone (pth) |
| CN101260398B (zh) * | 2007-03-07 | 2013-06-05 | 舒泰神（北京）生物制药股份有限公司 | 神经生长因子基因定位改造动物及其制备方法和应用 |
| JP5711966B2 (ja) | 2007-08-01 | 2015-05-07 | ザ ジェネラル ホスピタル コーポレイション | Ｇタンパク質共役受容体および関連組成物を使用するスクリーニング方法 |
| CN101927012B (zh) * | 2009-06-26 | 2013-08-14 | 丽珠医药集团股份有限公司 | 神经生长因子的病毒灭活方法 |
| MX358161B (es) | 2010-05-13 | 2018-08-06 | The General Hospital Corp Star | Analogos de hormona paratiroidea y usos para los mismos. |
| CN102816766A (zh) * | 2012-05-04 | 2012-12-12 | 沈阳医学院 | 蛇毒神经生长因子活性多肽的筛选方法 |
| WO2023004784A1 (zh) * | 2021-07-30 | 2023-02-02 | 成都优洛生物科技有限公司 | 一种重组cho细胞、其构建方法、利用其的检测系统和方法 |
| CN115894705A (zh) * | 2021-09-30 | 2023-04-04 | 三生国健药业（上海）股份有限公司 | 一种β-NGF融合蛋白、其制备方法及用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK161152C (da) * | 1983-03-03 | 1991-11-11 | Genentech Inc | Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat |
| US4796580A (en) * | 1987-09-11 | 1989-01-10 | Allied-Signal Inc. | Idle control valve for use with a throttle assembly of an internal combustion engine |
| JPH01211490A (ja) * | 1988-02-19 | 1989-08-24 | Tosoh Corp | ヒト神経成長因子遺伝子セグメント |
| US5272063A (en) * | 1988-11-22 | 1993-12-21 | Syntex (U.S.A.) Inc. | Process of making human nerve growth factor |
-
1989
- 1989-11-16 IT IT04856489A patent/IT1238348B/it active IP Right Grant
-
1990
- 1990-11-13 NZ NZ236058A patent/NZ236058A/xx unknown
- 1990-11-14 IL IL96347A patent/IL96347A/xx active IP Right Grant
- 1990-11-14 ZA ZA909122A patent/ZA909122B/xx unknown
- 1990-11-15 PT PT95911A patent/PT95911B/pt active IP Right Grant
- 1990-11-15 YU YU217890A patent/YU217890A/sh unknown
- 1990-11-15 CA CA002030108A patent/CA2030108C/en not_active Expired - Fee Related
- 1990-11-15 PE PE1990177640A patent/PE28191A1/es unknown
- 1990-11-15 IE IE412090A patent/IE904120A1/en unknown
- 1990-11-16 CN CN90109292A patent/CN1051934A/zh active Pending
- 1990-11-16 EP EP90121961A patent/EP0432510B1/en not_active Expired - Lifetime
- 1990-11-16 ES ES90121961T patent/ES2173856T3/es not_active Expired - Lifetime
- 1990-11-16 PL PL28781190A patent/PL287811A1/xx unknown
- 1990-11-16 AT AT90121961T patent/ATE214735T1/de not_active IP Right Cessation
- 1990-11-16 JP JP02312577A patent/JP3121611B2/ja not_active Expired - Fee Related
- 1990-11-16 HU HU907174A patent/HUT61047A/hu unknown
- 1990-11-16 KR KR1019900018690A patent/KR910009929A/ko not_active Ceased
- 1990-11-16 FI FI905691A patent/FI905691L/fi not_active IP Right Cessation
- 1990-11-16 DE DE69033937T patent/DE69033937T2/de not_active Expired - Fee Related
- 1990-11-19 AR AR90318408A patent/AR246983A1/es active
- 1990-12-28 TW TW079110979A patent/TW205069B/zh active
-
1993
- 1993-11-24 US US08/156,792 patent/US5457034A/en not_active Expired - Lifetime
-
2000
- 2000-05-02 JP JP2000133485A patent/JP2001000194A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT95911A (pt) | 1991-09-13 |
| JP3121611B2 (ja) | 2001-01-09 |
| PL287811A1 (en) | 1991-12-02 |
| FI905691A0 (fi) | 1990-11-16 |
| IT8948564A0 (it) | 1989-11-16 |
| CA2030108C (en) | 1998-04-28 |
| IE904120A1 (en) | 1991-05-22 |
| EP0432510A1 (en) | 1991-06-19 |
| HU907174D0 (en) | 1991-05-28 |
| IL96347A (en) | 1997-11-20 |
| EP0432510B1 (en) | 2002-03-20 |
| JP2001000194A (ja) | 2001-01-09 |
| IT1238348B (it) | 1993-07-13 |
| PT95911B (pt) | 1998-01-30 |
| DE69033937D1 (de) | 2002-04-25 |
| AR246983A1 (es) | 1994-10-31 |
| FI905691A7 (fi) | 1991-05-17 |
| PE28191A1 (es) | 1991-10-28 |
| TW205069B (enExample) | 1993-05-01 |
| AU645998B2 (en) | 1994-02-03 |
| IT8948564A1 (it) | 1991-05-16 |
| KR910009929A (ko) | 1991-06-28 |
| CN1051934A (zh) | 1991-06-05 |
| JPH03224490A (ja) | 1991-10-03 |
| CA2030108A1 (en) | 1991-05-17 |
| HUT61047A (en) | 1992-11-30 |
| DE69033937T2 (de) | 2002-11-14 |
| FI905691L (fi) | 1991-05-17 |
| ES2173856T3 (es) | 2002-11-01 |
| ATE214735T1 (de) | 2002-04-15 |
| AU6655890A (en) | 1991-05-23 |
| US5457034A (en) | 1995-10-10 |
| NZ236058A (en) | 1993-04-28 |
| ZA909122B (en) | 1991-09-25 |
| IL96347A0 (en) | 1991-08-16 |
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