YU102503A - Kondenzovani pirimidinski dhfr inhibitori kao antibakterijska sredstva - Google Patents
Kondenzovani pirimidinski dhfr inhibitori kao antibakterijska sredstvaInfo
- Publication number
- YU102503A YU102503A YU102503A YUP102503A YU102503A YU 102503 A YU102503 A YU 102503A YU 102503 A YU102503 A YU 102503A YU P102503 A YUP102503 A YU P102503A YU 102503 A YU102503 A YU 102503A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- antibacterials
- fused pyrimidine
- dhfr inhibitors
- dhfr
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Ovaj pronalazak se odnosi na nova heterociklična jedinjenja i na njihovu upotrebu u medicinskome tretmanu ili profilaksi bakterijskih infekcija, ili na njihovu upotrebu kao antiseptika ili sredstava za sterilizaciju ili dezinfekciju.[This invention relates to novel heterocyclic compounds and to their use in the medical treatment or prophylaxis of bacterial infections, or their use as antiseptics, sterilizants, or disinfectants.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30168501P | 2001-06-28 | 2001-06-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU102503A true YU102503A (sh) | 2006-08-17 |
Family
ID=23164426
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU102503A YU102503A (sh) | 2001-06-28 | 2002-06-28 | Kondenzovani pirimidinski dhfr inhibitori kao antibakterijska sredstva |
YU102303A YU102303A (sh) | 2001-06-28 | 2002-06-28 | Kondenzovani pirimidini kao inhibitori d-alanil-d-alanin ligaze |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU102303A YU102303A (sh) | 2001-06-28 | 2002-06-28 | Kondenzovani pirimidini kao inhibitori d-alanil-d-alanin ligaze |
Country Status (16)
Country | Link |
---|---|
US (3) | US7345048B2 (sh) |
EP (2) | EP1432713A4 (sh) |
CN (2) | CN1547472A (sh) |
BG (1) | BG108548A (sh) |
BR (1) | BR0211310A (sh) |
CA (2) | CA2451800A1 (sh) |
CZ (2) | CZ200442A3 (sh) |
EA (1) | EA200400094A1 (sh) |
EE (2) | EE200400043A (sh) |
HU (2) | HUP0700061A2 (sh) |
IL (2) | IL159540A0 (sh) |
MX (1) | MXPA04000159A (sh) |
PL (2) | PL374589A1 (sh) |
SK (1) | SK302004A3 (sh) |
WO (2) | WO2003001887A2 (sh) |
YU (2) | YU102503A (sh) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0217703D0 (en) * | 2002-07-31 | 2002-09-11 | Univ Liverpool | Pharmaceutical composition |
MX2007005408A (es) * | 2004-11-09 | 2007-05-16 | Hoffmann La Roche | Compuestos de aminoquinazolinas. |
ATE449097T1 (de) * | 2005-07-21 | 2009-12-15 | Hoffmann La Roche | Pyridoä2,3-düpyrimidin-2,4-diamin-verbindungen als ptpib-hemmer |
GB0608822D0 (en) * | 2006-05-04 | 2006-06-14 | Chroma Therapeutics Ltd | Inhibitors of DHFR |
SI22338A (sl) * | 2006-08-18 | 2008-02-29 | Univerza V Ljubljani, Fakulteta Za Farmacijo | Diazendikarboksamidi kot inhibitorji d-alanil-d-alanin ligaze |
TW200831528A (en) | 2006-11-30 | 2008-08-01 | Astrazeneca Ab | Compounds |
CN101084901B (zh) * | 2007-06-22 | 2011-12-21 | 复旦大学 | 一种葡萄球菌抑制剂 |
KR20100116206A (ko) * | 2008-02-01 | 2010-10-29 | 다케다 야쿠힌 고교 가부시키가이샤 | Hsp90 저해제로서의 옥심 유도체 |
GB2480791B (en) * | 2009-03-20 | 2014-11-05 | Univ Texas | Method for imparting antimicrobial activity to a medical device |
EA022487B1 (ru) * | 2009-08-31 | 2016-01-29 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Птеридины, полезные в качестве агрохимикатов и продуктов для здоровья животных |
SI3097102T1 (en) | 2015-03-04 | 2018-02-28 | Gilead Sciences, Inc. | A TOOL RECEPTOR MODULING 4,6-DIAMINO-PYRIDO (3,2-D) PYRIMIDINE COMPOUNDS |
CN106316966A (zh) * | 2015-06-15 | 2017-01-11 | 董运勤 | 医药中间体n-(2-吡嗪甲基)苄胺磷酸盐化合物制备方法 |
ES2826748T3 (es) | 2016-09-02 | 2021-05-19 | Gilead Sciences Inc | Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll |
US10370342B2 (en) | 2016-09-02 | 2019-08-06 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
AU2018214554C1 (en) | 2017-02-01 | 2022-12-15 | Novo Nordisk A/S | Treatment of diuretic resistance |
JP7395479B2 (ja) | 2018-01-05 | 2023-12-11 | ノヴォ ノルディスク アー/エス | 免疫抑制なしにil-6媒介性炎症を処置する方法 |
US20220119354A1 (en) * | 2019-02-01 | 2022-04-21 | Fmc Corporation | Diamino-substituted pyridines and pyrimidines as herbicides |
TWI751517B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TWI751516B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
GB2626567A (en) * | 2023-01-26 | 2024-07-31 | De Montfort Univ | Quinazoline derivatives for use as a medicament |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2949466A (en) * | 1958-03-04 | 1960-08-16 | Parke Davis & Co | Pyrimidine compounds and means of producing the same |
US3134778A (en) * | 1963-08-20 | 1964-05-26 | Smith Kline French Lab | 2,5,7-triamino-4-phenyl (or thienyl)-pyrimido[4,5-d]pyrimidines |
RO56210A2 (sh) | 1970-12-28 | 1974-08-01 | ||
US4079056A (en) * | 1975-03-31 | 1978-03-14 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Method of making pteridine compounds |
DE2750288A1 (de) * | 1977-11-10 | 1979-05-17 | Thomae Gmbh Dr K | Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
DE3445298A1 (de) * | 1984-12-12 | 1986-06-12 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel |
WO1992017478A1 (en) | 1991-04-08 | 1992-10-15 | Duquesne University Of The Holy Ghost | 5-ALKYL-6-[[AMINO]METHYL]PYRIDO[2,3-d]PYRIMIDINE DERIVATIVES AND METHODS OF PREPARING AND USING THESE DERIVATIVES |
US5547954A (en) | 1994-05-26 | 1996-08-20 | Fmc Corporation | 2,4-Diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides |
DE59610771D1 (de) * | 1995-02-27 | 2003-11-20 | Hoffmann La Roche | Dioxopyrrolo-pyrrolderivate |
WO1999050264A1 (fr) | 1998-03-30 | 1999-10-07 | Kyowa Hakko Kogyo Co., Ltd. | Derives de quinazoline |
JP2000239277A (ja) | 1999-02-19 | 2000-09-05 | Kyowa Hakko Kogyo Co Ltd | イミダゾキナゾリン誘導体 |
GB0219893D0 (en) | 2002-08-27 | 2002-10-02 | Melacure Therapeutics Ab | Pharmaceutically active compounds |
-
2002
- 2002-06-28 IL IL15954002A patent/IL159540A0/xx unknown
- 2002-06-28 YU YU102503A patent/YU102503A/sh unknown
- 2002-06-28 CZ CZ200442A patent/CZ200442A3/cs unknown
- 2002-06-28 EA EA200400094A patent/EA200400094A1/ru unknown
- 2002-06-28 CN CNA028166604A patent/CN1547472A/zh active Pending
- 2002-06-28 EE EEP200400043A patent/EE200400043A/xx unknown
- 2002-06-28 CN CNA028150651A patent/CN1543465A/zh active Pending
- 2002-06-28 YU YU102303A patent/YU102303A/sh unknown
- 2002-06-28 CZ CZ200443A patent/CZ200443A3/cs unknown
- 2002-06-28 IL IL15953802A patent/IL159538A0/xx unknown
- 2002-06-28 CA CA002451800A patent/CA2451800A1/en not_active Abandoned
- 2002-06-28 WO PCT/US2002/020567 patent/WO2003001887A2/en not_active Application Discontinuation
- 2002-06-28 EP EP02753353A patent/EP1432713A4/en not_active Withdrawn
- 2002-06-28 HU HU0700061A patent/HUP0700061A2/hu unknown
- 2002-06-28 BR BRPI0211310-4A patent/BR0211310A/pt not_active IP Right Cessation
- 2002-06-28 SK SK30-2004A patent/SK302004A3/sk not_active Application Discontinuation
- 2002-06-28 PL PL02374589A patent/PL374589A1/xx not_active Application Discontinuation
- 2002-06-28 PL PL02374259A patent/PL374259A1/xx unknown
- 2002-06-28 EP EP02759101A patent/EP1411949A4/en not_active Withdrawn
- 2002-06-28 EE EEP200400042A patent/EE200400042A/xx unknown
- 2002-06-28 US US10/185,059 patent/US7345048B2/en not_active Expired - Fee Related
- 2002-06-28 WO PCT/US2002/020479 patent/WO2003002064A2/en active Search and Examination
- 2002-06-28 MX MXPA04000159A patent/MXPA04000159A/es not_active Application Discontinuation
- 2002-06-28 HU HU0700040A patent/HUP0700040A2/hu unknown
- 2002-06-28 US US10/184,855 patent/US20030176436A1/en not_active Abandoned
- 2002-06-28 CA CA002451840A patent/CA2451840A1/en not_active Abandoned
-
2004
- 2004-01-28 BG BG108548A patent/BG108548A/bg unknown
-
2007
- 2007-12-05 US US11/951,214 patent/US20080090847A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1547472A (zh) | 2004-11-17 |
EP1432713A4 (en) | 2005-05-11 |
SK302004A3 (sk) | 2005-07-01 |
WO2003002064A2 (en) | 2003-01-09 |
WO2003002064A3 (en) | 2003-10-23 |
EE200400042A (et) | 2004-10-15 |
CA2451800A1 (en) | 2003-01-09 |
CA2451840A1 (en) | 2003-01-09 |
HUP0700061A2 (en) | 2007-05-02 |
CZ200442A3 (cs) | 2004-10-13 |
WO2003001887A2 (en) | 2003-01-09 |
WO2003001887A3 (en) | 2003-08-21 |
YU102303A (sh) | 2006-08-17 |
PL374589A1 (en) | 2005-10-31 |
EE200400043A (et) | 2004-10-15 |
IL159540A0 (en) | 2004-06-01 |
PL374259A1 (en) | 2005-10-03 |
CN1543465A (zh) | 2004-11-03 |
CZ200443A3 (cs) | 2004-08-18 |
BR0211310A (pt) | 2006-10-31 |
HUP0700040A2 (en) | 2007-05-29 |
EA200400094A1 (ru) | 2005-08-25 |
EP1411949A4 (en) | 2004-11-24 |
EP1411949A2 (en) | 2004-04-28 |
US20080090847A1 (en) | 2008-04-17 |
US7345048B2 (en) | 2008-03-18 |
BG108548A (bg) | 2005-05-31 |
US20030176436A1 (en) | 2003-09-18 |
IL159538A0 (en) | 2004-06-01 |
US20030181470A1 (en) | 2003-09-25 |
MXPA04000159A (es) | 2005-01-07 |
EP1432713A2 (en) | 2004-06-30 |
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