Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/73—Polysaccharides
  • A61K8/731—Cellulose; Quaternized cellulose derivatives
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/0216—Solid or semisolid forms
  • A61K8/022—Powders; Compacted Powders
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/0241—Containing particulates characterized by their shape and/or structure
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/0241—Containing particulates characterized by their shape and/or structure
  • A61K8/025—Explicitly spheroidal or spherical shape
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/0241—Containing particulates characterized by their shape and/or structure
  • A61K8/0254—Platelets; Flakes
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
  • A61K8/25—Silicon; Compounds thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
  • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/73—Polysaccharides
  • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/04—Preparations containing skin colorants, e.g. pigments for lips
  • A61Q1/06—Lipsticks
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/02—Preparations containing skin colorants, e.g. pigments
  • A61Q1/10—Preparations containing skin colorants, e.g. pigments for eyes, e.g. eyeliner, mascara
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/12—Face or body powders for grooming, adorning or absorbing
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
  • A61Q17/005—Antimicrobial preparations
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
  • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
  • A61K2800/41—Particular ingredients further characterized by their size
  • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
  • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
  • A61K2800/60—Particulates further characterized by their structure or composition
  • A61K2800/65—Characterized by the composition of the particulate/core
  • A61K2800/652—The particulate/core comprising organic material
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
  • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

• the present invention relates to a powder composition for cosmetics or external skin preparations and a method for producing the same.
• Plastic powders such as nylon powder, acrylic powder, and urethane powder may be added to cosmetics for the purpose of improving the feel and slipperiness during application.
• Japanese Patent Application Laid-Open No. 2020-97552 describes (a) 6 to 10% by weight of fumes-like hydrophobicized silica, (b) 5 to 20% by weight of octamethyltrisiloxane and / or decamethyltetrasiloxane, and (c) batil. Described are unevenness-correcting cosmetics containing 10 to 30% by weight of powders other than alcohol and (d) microplastic beads (a) and which do not contain microplastic beads.
• Japanese Patent Application Laid-Open No. 2020-50840 describes a cosmetic containing porous cellulose particles formed by aggregating specific crystalline celluloses.
• Japanese Patent Application Laid-Open No. 2020-152851 describes a cosmetic composition containing specific cellulose derivative particles.
• plastic powders such as nylon powders, acrylic powders, or urethane powders.
• An object of the present invention is to provide a powder composition that can be used for cosmetics and external preparations for skin, instead of plastic powder such as nylon powder, acrylic powder, or urethane powder.
• the present inventors have found for the first time that a powder composition containing a specific acyl lysine and cellulose and / or starch in a specific blending amount can solve the above problems, and the present invention has been developed. It came to be completed. That is, the present invention is as follows. [1] (A) Acrylidine and (B) Cellulose and / or starch and (A) A powder composition having a median diameter of 9 ⁇ m or less in the volume-based distribution of acyllysine. When the whole powder composition is 100% by mass, The content of (A) is 2 to 40% by mass, and the content is 2 to 40% by mass.
• the content of (B) is 3 to 95% by mass, and the content is 3 to 95% by mass.
• the total amount of the (A) and the (B) is 10% by mass or more.
• Composition. [2] (A) Acrylidine and (B) Cellulose and / or starch and Is a powder composition containing When the whole powder composition is 100% by mass, The content of (A) is 2 to 40% by mass, and the content is 2 to 40% by mass.
• the content of (B) is 3 to 95% by mass, and the content is 3 to 95% by mass.
• the total amount of the above (A) and the above (B) is 10% by mass or more, and the amount is 10% by mass or more.
• the water repellent time using the 35% by mass ethanol aqueous solution is 30 minutes or more, and the water repellent time using the 35% by mass ethanol aqueous solution is 30 mg on the liquid surface by putting 5 g of the 35% by mass ethanol aqueous solution in a 10 mL glass vial. Is the time it takes for the powder composition to be placed and all the powder composition to settle.
• Composition. [3] (A) Acrylidine and (B) Cellulose and / or starch and Is a powder composition containing When the whole powder composition is 100% by mass, The content of (A) is 2 to 40% by mass, and the content is 2 to 40% by mass.
• the content of (B) is 3 to 95% by mass, and the content is 3 to 95% by mass.
• the total amount of the above (A) and the above (B) is 10% by mass or more, and the amount is 10% by mass or more.
• the water repellent time using a 30% by mass ethanol aqueous solution is 60 minutes or more, and the water repellent time using a 30% by mass ethanol aqueous solution is 30 mg on the liquid surface in a 10 mL glass vial containing 5 g of a 30% by mass aqueous solution of ethanol. Is the time it takes for the powder composition to be placed and all the powder composition to settle.
• Composition [4] The composition according to any one of 1 to 3 above, wherein the composition (B) contains plate-like cellulose.
• composition according to 4 above which contains 5 to 65% by mass of plate-like cellulose when the total powder composition is 100% by mass.
• the composition according to any one of 1 to 5 above which contains 5 to 90% by mass of starch when the whole powder composition is 100% by mass.
• the composition according to any one of 1 to 6 above wherein the composition (B) contains spherical cellulose.
• the composition according to 7 above which contains 5 to 95% by mass of spherical cellulose when the total powder composition is 100% by mass.
• composition according to any one of 1 to 8 above further comprising (C) silica.
• the production method according to 20 or 21, wherein the mixing comprises mixing by dry mixing.
• the production method according to any one of 20 to 22, wherein the mixing comprises mixing by a mixer for 120 minutes or less.
• the powder composition of the present invention contains (A) acyl lysine, (B) cellulose and / or starch, and (A) the median diameter of the volume-based distribution of acyl lysine is 9 ⁇ m or less.
• the (A) acyllysine contained in the powder composition of this embodiment has a median diameter of 9 ⁇ m or less in a volume-based distribution, preferably 6 ⁇ m or less from the viewpoint of improving adhesion, and further improving adhesion and feel. It is more preferably 5 ⁇ m or less, and further preferably 4 ⁇ m or less from the viewpoint of improving adhesion and shortening the production time.
• the median diameter of the number-based distribution of (A) acyllysine in this embodiment is preferably 4 ⁇ m or less, preferably 3 ⁇ m or less from the viewpoint of improving adhesion, and further preferably 2 ⁇ m or less from the viewpoint of improving adhesion and shortening the production time. be.
• the median diameter of acyllysine can be determined by measuring the particle size distribution based on the number or volume using a laser diffraction / scattering type particle size distribution measuring device.
• the median diameter means the particle diameter at the point where the distribution curve of the accumulated passage amount intersects the horizontal axis of 50%.
• the "number-based distribution” represents the particle size distribution calculated based on the number of particles counted when calculating the frequency of each particle size in the particle size distribution, and is the "volume-based distribution”. Refers to the particle size distribution calculated based on the value obtained by counting the volumes of particles assumed to be spherical when calculating the frequency of each particle size of the particle size distribution.
• the bulk density of (A) acyllysine is preferably 0.38 g / mL or less.
• the bulk density is preferably 0.01 to 0.38 g / mL, more preferably 0.05 to 0.38 g / mL, and even more preferably 0.1 to 0.32 g / mL.
• the bulk density of acyllysine can be measured by the following measuring method. The acyl lysine is crushed by stirring with a mixer for 2 minutes or more, and the bulk density of the obtained crystals is measured using a powder fluidity analyzer (for example, powder rheometer FT-4 (manufactured by Freeman Technology TM )).
• the powder composition of the present invention also contains (A) acyllysine, (B) cellulose and / or starch, and has a water repellency time of 30 minutes or more using a 35% by mass aqueous solution of ethanol.
• the water repellent time using a 35% by mass aqueous solution of ethanol was such that 5 g of a 35% by mass aqueous solution of ethanol was placed in a 10 mL glass vial, a 30 mg powder composition was placed on the liquid surface, and all the powder compositions settled. It is the time it takes.
• the water repellent time using the 35% by mass aqueous solution of ethanol is preferably 40 minutes or more, more preferably 60 minutes or more.
• the powder composition of the present invention also contains (A) acyllysine, (B) cellulose and / or starch, and has a water repellency time of 60 minutes or more using a 30% by mass aqueous solution of ethanol.
• the water repellent time using a 30% by mass aqueous solution of ethanol was such that 5 g of a 30% by mass aqueous solution of ethanol was placed in a 10 mL glass vial, a 30 mg powder composition was placed on the liquid surface, and all the powder compositions settled. It is the time it takes.
• the method for producing acyllysine having a volume-based distribution with a median diameter of 9 ⁇ m or less can be obtained by a production method in which a basic solution of acyllysine is dropped into a solution such as hydrochloric acid and crystallized, or a pulverization method using a machine or the like. can.
• Acyllysine having a volume-based distribution with a median diameter of 9 ⁇ m or less can be obtained, for example, by the method described in WO2020 / 262367.
• the acyl group of (A) acyl lysine is a saturated or unsaturated fatty acid acyl having 8 to 22 carbon atoms, for example, octanoyl, lauroyl, myristoyl, palmitoyl, stearoyl, octyldodecyl, oleyl, behenyl, coconut oil fatty acid acyl, palm kernel oil.
• fatty acid acyls and beef fatty acid acyls but one or more selected from the group consisting of lauroyl and octanoyl is preferable in that they can be obtained for general purposes.
• the powder composition of the present invention contains (B) cellulose and / or starch. That is, an embodiment containing (B-1) cellulose, (B-2) starch, or (B-3) cellulose and starch is included.
• cellulose include plate-shaped cellulose, spherical cellulose, amorphous cellulose and the like.
• Examples of the plate-shaped cellulose include plate-shaped crystalline cellulose and needle-shaped crystalline cellulose, and plate-shaped crystalline cellulose is preferable.
• the average particle size of the plate-shaped cellulose is preferably 2 to 50 ⁇ m, more preferably 5 to 30 ⁇ m, and even more preferably 8 to 20 ⁇ m.
• the average particle size of the plate-shaped cellulose is specified as in JIS standard (Z8819-2: 2019).
• the spherical cellulose examples include non-porous cellulose and porous cellulose, and non-porous cellulose is preferable.
• the spherical shape includes a true spherical shape, a substantially spherical shape, and an elliptical shape.
• the average particle size of the spherical cellulose is preferably 2 to 30 ⁇ m, more preferably 3 to 20 ⁇ m, and even more preferably 5 to 10 ⁇ m.
• the average particle size of the spherical cellulose is specified as in JIS standard (Z8819-2: 2019).
• As the cellulose those registered as crystalline cellulose, cellulose, cellulose acetate, and lignin can be used as INCI names.
• Cellulose is commercially available, and for example, TEGO Feel Green manufactured by Evonik Industries, CELLUBLOBEADS D-5 manufactured by Daito Kasei Kogyo Co., Ltd., and CELLLULOBEADS D-10 can be used.
• starch examples include rice starch, corn starch, potato starch, tapioca starch, pregelatinized starch, partially pregelatinized starch and the like.
• Rice starch, corn starch, potato starch are preferable, and corn starch is more preferable. It is preferable to use rice starch, corn starch, potato starch, and tapioca starch registered as INCI names.
• the average particle size of starch is preferably 5 to 30 ⁇ m, more preferably 5 to 25 ⁇ m, and even more preferably 5 to 20 ⁇ m.
• the average particle size of starch is specified as in JIS standard (Z8819-2: 2019).
• Starch is commercially available, and for example, ST Starch P manufactured by Nissho Kagaku Co., Ltd. can be used.
• the powder composition of the present invention is a powder composition containing (A) acyllysine and (B) cellulose.
• the acyl lysine is preferably lauroyl lysine, more preferably crystalline lauroyl lysine.
• the cellulose is preferably plate-shaped cellulose or spherical cellulose, and more preferably plate-shaped cellulose.
• the powder composition of the present invention is a powder composition containing (A) acyllysine and (B) cellulose and starch.
• the acyl lysine is preferably lauroyl lysine, more preferably crystalline lauroyl lysine.
• the cellulose is preferably plate-shaped cellulose or spherical cellulose, and more preferably plate-shaped cellulose.
• the starch is preferably cornstarch.
• the powder composition of the present invention may further contain (C) silica.
• silica spherical or irregularly shaped silica can be used, which may have a porous shape, a non-porous shape, a hollow shape, or the like, respectively. It is preferably non-porous spherical silica, porous spherical silica, and more preferably porous spherical silica.
• the average particle size of silica is preferably 1 to 50 ⁇ m, more preferably 3 to 20 ⁇ m, and even more preferably 5 to 12 ⁇ m.
• the average particle size of silica is specified as in JIS standard (Z8819-2: 2019).
• Silica is commercially available, for example, porous silica beads SB-300, SB-700 manufactured by Miyoshi Kasei, Inc., Sunsphere H-31, H-51, H-121, L manufactured by AGC Si-Tech Co., Ltd. -31 and L-51 can be used.
• the powder composition of the present invention there is a powder composition containing (A) acyllysine, (B) cellulose, and (C) silica.
• the acyl lysine is preferably lauroyl lysine, more preferably crystalline lauroyl lysine.
• the cellulose is preferably plate-shaped cellulose or spherical cellulose, and more preferably plate-shaped cellulose.
• the silica is preferably non-porous spherical silica, porous spherical silica, and more preferably porous spherical silica.
• the powder composition of the present invention there is a powder composition containing (A) acyllysine, (B) starch, and (C) silica.
• the acyl lysine is preferably lauroyl lysine, more preferably crystalline lauroyl lysine.
• the starch is preferably cornstarch.
• the silica is preferably non-porous spherical silica, porous spherical silica, and more preferably porous spherical silica.
• the powder composition of the present invention may further contain (D) lysine or a salt thereof.
• lysine salt include lysine hydrochloride, which are commercially available, and for example, lysine hydrochloride manufactured by Ajinomoto Co., Inc. can be used.
• (A) the median diameter of the volume-based distribution is 9 ⁇ m or less.
• examples thereof include an acyl lysine, (B-1) cellulose, and (C) silica.
• (A) the median diameter of the volume reference distribution is 9 ⁇ m or less.
• Embodiments include acyl lysine, (B-2) starch, and (C) silica.
• the median diameter of the volume-based distribution is 9 ⁇ m or less.
• examples include acyl lysine, (B-3) cellulose and starch.
• carbon polymerized particles for example, polyacrylic polyethylene / polystyrene
• acyllysine having a volume-based distribution having a median diameter of 9 ⁇ m or less examples include embodiments containing cellulose and starch.
• a sixth embodiment preferably includes (A) an acyl lysine having a median diameter of 9 ⁇ m or less in a volume-based distribution, and (B-1) cellulose.
• the cellulose is preferably spherical cellulose.
• a seventh embodiment preferably includes (A) acyl lysine having a median diameter of 9 ⁇ m or less in a volume-based distribution, and (B-3) cellulose and starch. .. (B-1)
• the cellulose is preferably spherical cellulose.
• the content of the (A) acyl lysine is 2 to 40% by mass, preferably 5 to 20% by mass, assuming that the entire powder composition is 100% by mass. If the content of acyl lysine is less than 2% by mass, the water repellency is inferior, and if the content of acyl lysine exceeds 40% by mass, the adhesion to the skin becomes strong and the feel becomes poor.
• the total amount of the (A) and the (B) is at least 10% by mass or more when the total amount of the powder composition is 100% by mass. It is preferably 20% by mass or more, and more preferably 35% by mass or more.
• the content of (B) cellulose and / or starch is 3 to 95% by mass, preferably 25 to 95% by mass, assuming that the entire powder composition is 100% by mass.
• the content of cellulose is preferably 5 to 95% by mass, more preferably 5 to 60, based on 100% by mass of the entire powder composition. It is by mass, more preferably 5 to 40% by mass.
• plate-shaped cellulose it is preferably 5 to 95% by mass, more preferably 5 to 60% by mass, and further preferably 5 to 40% by mass.
• spherical cellulose it is preferably 5 to 95% by mass, more preferably 5 to 60% by mass, and further preferably 5 to 40% by mass.
• the starch content is preferably 5 to 95% by mass, more preferably 20 to 90%, based on 100% by mass of the entire powder composition. It is mass%.
• the respective contents of cellulose and starch are preferably 5 to 75% by mass of cellulose when the whole powder composition is 100% by mass: starch. It is 20 to 90% by mass, more preferably 5 to 40% by mass of cellulose: 55 to 90% by mass of starch.
• the content of (C) is 30 to 90% by mass, preferably 50 to 80% by mass, assuming that the entire powder composition is 100% by mass.
• the powder composition contains (D) lysine or a salt thereof, the content of (D) is 0.0001 to 1% by mass when the total amount of the powder composition is 100% by mass.
• (A) 2 to 30% by mass of acylidine having a median diameter of 9 ⁇ m or less, (B-1) 5 to 40% by mass of cellulose, and (C) silica 30 to 93 are preferable.
• Examples include an aspect containing mass%.
• (A) 2 to 30% by mass of acylidine having a median diameter of 9 ⁇ m or less, (B-2) 5 to 40% by mass of starch, and (C) 30 to 93% of silica are preferable. Examples include an aspect containing mass%.
• the third aspect is preferably (A) 2 to 20% by mass of acyllysine having a median diameter of 9 ⁇ m or less, and (B-3) 1 to 38% by mass and 60 to 97% by mass of cellulose and starch, respectively. % May be included.
• the third aspect contains (C) silica, (A) 2 to 20% by mass of acyllysine having a volume-based distribution with a median diameter of 9 ⁇ m or less, and (B-3) 5 to 30% by mass of cellulose and starch, respectively. , 25 to 90% by mass, and (C) 3 to 78% by mass of silica.
• the fourth aspect is preferably (A) 2 to 20% by mass of acylidine having a median diameter of 9 ⁇ m or less, (B-2) 20 to 50% by mass of starch, and (C) 30 to 78% of silica.
• Examples include an aspect containing mass%.
• As the fifth aspect preferably, (A) 2 to 20% by mass of acyllysine having a median diameter of 9 ⁇ m or less, and (B-3) 1 to 97% by mass of cellulose and starch, respectively, 1 to 97% by mass. % May be included.
• the sixth embodiment preferably includes (A) 5 to 40% by mass of acylidine having a median diameter of 9 ⁇ m or less, and (B-1) 60 to 95% by mass of cellulose.
• the cellulose is preferably spherical crystalline cellulose.
• the seventh aspect is preferably (A) 5 to 40% by mass of acylidine having a median diameter of 9 ⁇ m or less, and (B-3) 10 to 40% by mass and 50 to 85% by mass of cellulose and starch, respectively. % May be included.
• the cellulose is preferably spherical crystalline cellulose.
• the powder composition of the present invention can be obtained by adding and mixing the acyl lysine and the cellulose and / or starch.
• the addition of acyllysine and cellulose and / or starch can also be added at the same time.
• the powder composition of the present invention contains (C) silica
• the powder composition of the present invention can be obtained by adding and mixing the acyl lysine, the cellulose and / or the starch and the silica. ..
• the addition of acyllysine and cellulose and / or starch and the above silica can also be added at the same time.
• the mixing of the acyl lysine can be carried out by dry mixing.
• the dry-type mixing in the present invention includes a mode in which a solvent is completely not used, and also includes a mode in which a small amount of solvent is used. Further, the mixing of the acyl lysine can be carried out by mixing with a mixer for 1 minute or more.
• the mixing time is preferably 1 minute or longer, more preferably 10 minutes or longer.
• the mixing time is preferably 120 minutes or less from the viewpoint that the product can be produced at low cost without reducing the productivity.
• Mixers include high-speed stirring mixers such as Henshell mixers, household mixers, and high-share mixers; containers such as W-type mixers, CV-type mixers, V-type mixers, and locking mixers.
• Rotary mixer Ribbon stirring type, Double axis paddle type, Biaxial planetary stirring type, Conical screw type mechanical stirring type mixer; Air flow stirring type mixer, Julia mixer, Nauter mixer, Nobilta, etc.
• a shock type mixer or the like can be used, and a high speed stirring type mixer is preferable from the viewpoint of inexpensive production and versatility.
• composition of the present invention can also be used as a cosmetic or a skin external preparation.
• the cosmetic or external skin preparation can be prepared in any form applicable to, for example, a desired site (eg, skin, hair, scalp, lips, eyes, eyelashes, eyelids, nails) according to a conventional method. ..
• Cosmetics or external preparations for skin, lips, eyelashes, and nails include, for example, sunscreens, body powders, sunscreens such as sprays, foundations, grate, primer, BB cream, body color, bronzer, face powder, loose powder, etc.
• cosmetics or external preparations for hair include hair styling products, hair emulsions, hair treatments, hair conditioners, and hair lotions.
• cosmetics or external preparations for the scalp include hair growth agents.
• Preferred cosmetics include, for example, make-up makeup, eye makeup makeup, lip cosmetics, and leave-on cosmetics.
• Preferred external preparations include, for example, ointments, creams, mousses and gels. Particularly preferred uses of the present invention include make-up cosmetics.
• the cosmetic When used as a cosmetic or a skin external preparation, the cosmetic usually contains ingredients that can be used in cosmetics (including external pharmaceutical agents and quasi-drugs) as long as the effects of the present invention are not impaired. May be.
• ingredients that can be used in cosmetics (including external pharmaceutical agents and quasi-drugs) as long as the effects of the present invention are not impaired. May be.
• Polymers eg, hydroxyethyl cellulose
• film-forming polymers eg, film-forming polymers
• gelling agents eg, dibutyllauroylglutamide, dibutylethylhexanoylglutamide
• moisturizers eg, sodium pyrrolidone carboxylate
• bactericides eg, sodium pyrrolidone carboxylate
• Anti-inflammatory agents eg, painkillers, antifungal agents, keratin softening and stripping agents, skin coloring agents, hormone agents, ultraviolet absorbers, hair growth agents, anti-sweating agents and astringent active ingredients (eg, pyrrolidone carboxylic acid zinc salt), sweat deodorant Agents, vitamins, blood flow promoters (vasodilators, blood circulation promoters), crude drugs, plant extracts, pH adjusters, chelating agents (eg, EDTA-2Na), viscosity modifiers, pearlizing agents, natural fragrances, Synthetic fragrances, pigments and pigments (eg Red 202, Blue 1), antioxidants (eg tocopherols, tocopherol acetate, pentagalloyl glucoside), preservatives (eg methylparaben, butylparaben, propylparaben, phenoxyethanol) , Emulsifiers, thickeners, fats and waxes, silicone compounds, perfume oils and the like.
• oil agent examples include higher alcohols such as octyldodecanol and oleyl alcohol; hydrocarbon oils such as squalane, liquid paraffin, hydrogenated polyisobutene and isododecane; jojoba seed oil, isononyl isononanoate, isostearyl neopentanoate and 2-ethylhexane.
• higher alcohols such as octyldodecanol and oleyl alcohol
• hydrocarbon oils such as squalane, liquid paraffin, hydrogenated polyisobutene and isododecane
• jojoba seed oil isononyl isononanoate, isostearyl neopentanoate and 2-ethylhexane.
• Examples of the inorganic powder include yellow iron oxide, red iron oxide, black iron oxide, fine particle iron oxide, bismuth oxychloride, zirconium oxide, magnesium oxide, chromium oxide, cobalt oxide, carbon black, ultramarine, dark blue, and zinc oxide.
• the inorganic powder may be a composite of the above-mentioned ones (for example, silica-coated titanium oxide, mica-coated titanium oxide, titanium-coated mica), and the above-mentioned ones may be treated with a silicone, a fluorine compound, or a silane coupling agent.
• Surface-treated eg, silicone-treated talc
• Silicone treated mica, Silicone treated sericite, Silicone treated titanium oxide, Silicone treated red iron oxide, Silicone treated iron oxide, Silicone treated black iron oxide, Stearoyl glutamate treated titanium oxide, Stearoyl glutamate treated yellow iron, Stearoyl glutamic acid treated red Iron oxide, stearoyl glutamate-treated black iron oxide, aluminum stearate-treated titanium oxide, etc.) may be used.
• Method for measuring various particle sizes of acyllysine A laser diffraction / scattering type particle size distribution measuring device (HORIBA, Partica LA-950) was used, and the particle size distribution was measured using the volume cumulative value. Various particle diameters of the number-based distribution and the volume-based distribution were obtained by analyzing the measurement results using the software attached to the device. 20 mg of acyllysine was added to 5 g of isopropyl alcohol, and the mixture was crushed and dispersed by exposure to ultrasonic waves for 30 minutes using an ultrasonic device with an output of 300 Watt. An appropriate amount of this dispersion was added to 500 mL isopropyl alcohol according to the procedure of the apparatus, and a dispersion sample having an appropriate concentration was prepared while checking the transparency.
• N ⁇ -lauroyl lysine a solution of N ⁇ -lauroyl lysine was added over 75 minutes while maintaining the pH at 0.7 to 1.3. Dropped. After completion of the dropping, the pH was adjusted to 7.0 with sodium hydroxide, the precipitated crystals were filtered and dried under reduced pressure to obtain 36.0 g of white crystals. The median diameter of the volume-based distribution of the obtained crystals was 9 ⁇ m. By lowering the temperature of the hydrochloric acid aqueous solution in which the solution of N ⁇ -lauroyl lysine is dropped, N ⁇ -lauroyl lysine having a smaller median diameter in the volume reference distribution can be obtained.
• N ⁇ -lauroyl lysine (trade name: Amihope) using a picoline (swirl flow type jet mill) manufactured by Hosokawa Micron Co., Ltd. at a supply gas pressure of 0.60 MPa, a crushed gas pressure of 0.60 MPa, and a supply speed of 49.3 g / h. LL (manufactured by Ajinomoto Co., Inc.) was pulverized to obtain N ⁇ -lauroyl lysine. The median diameter of the volume-based distribution of the obtained N ⁇ -lauroyl lysine was 3.2 ⁇ m.
• Sensory evaluation method We interviewed five specialized panels on the five evaluation items of silky feeling, moist feeling, rolling feeling, adhesion to the skin, and soft feeling, and when the comparative control score was 5, the following evaluation items were given. The score of the evaluation item was determined by the average score of 5 people. Further, it was judged in 5 stages from A to E based on the average value of the scores of each evaluation item.
• Score (Evaluation) 6: Very good 5: Good 4: Somewhat good 3: Slightly defective 2: Defective 1: Very bad (Judgment): (Average score) A: 5.0 or above B: 4.4-4.9 C: 3.9-4.3 D: 3.1-3.8 E: 3.0 or less
• Example 1-1 to 1-7 and Comparative Examples 1-1 to 1-2 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 1, and all the raw materials were simultaneously charged into a lab miller (Tescom Mill & Mixer TML162). The evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing). Table 1 shows the evaluation results when nylon (manufactured by Toray Industries, Inc., SP-500) was used as a comparative control. The scores of each evaluation item are shown in Table 2-1.
• the water repellency time was evaluated for the evaluation sample.
• the evaluation method was as follows: 5 g of a 30% by mass or 35% by mass aqueous solution of ethanol was placed in a 10 mL glass vial, 30 mg of each evaluation sample was gradually added from above, and the time during which the evaluation sample remained on the liquid surface was defined as the water repellent time. ..
• the evaluation results are shown in Table 2-2.
• Examples 2-1 to 2-12 and Comparative Examples 2-1 to 2-4 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratios (% by mass) shown in Tables 3-1 to 3-3, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time. ..
• the evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Tables 3-1 to 3-3 show the evaluation results when nylon (manufactured by Toray Industries, Inc., SP-500) was used as a comparative control.
• Examples 3-1 to 3-3 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 4, and all the raw materials were simultaneously charged into a lab miller (Tescom Mill & Mixer TML162). The evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing). Table 4 shows the evaluation results when nylon (manufactured by Toray Industries, Inc., SP-500) was used as a comparative control.
• nylon manufactured by Toray Industries, Inc., SP-500
• Examples 4-1 to 4-11 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 5-1 and Table 5-2, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time. ..
• the evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Tables 5-1 and 5-2 show the evaluation results when nylon (Toray Industries, Inc., SP-500) was used as a comparative control.
• Examples 5-1 to 5-4 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 6-1 and Table 6-2, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time. ..
• the evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Tables 6-1 and 6-2 show the evaluation results when PMMA particles (manufactured by Matsumoto Yushi Pharmaceutical Co., Ltd .: Matsumoto Microsphere M-100) were used as comparative controls.
• Examples 6-1 to 6-14 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratios (% by mass) shown in Tables 7-1 to 7-3, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time. ..
• the evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Tables 7-1 to 7-3 show the evaluation results when urethane particles (manufactured by Dainichiseika Kogyo Co., Ltd .: Dimic beads) are used as comparative controls.
• Examples 7-1 to 7-4 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 8, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time.
• the evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Five expert panels evaluated the lack of dryness when applying various mixtures according to the following criteria. Dryness evaluation method at the time of application: 1) I don't feel the dry feeling at all when applying ... 4 points 2) I hardly feel the dry feeling when applying ...
• AGC SAITEC Average particle size 5 ⁇ m * 2 Made by Evonik Operations (TEGO Feel): Average particle size 30 ⁇ m * 4 Ajinomoto Amihope LL: Median diameter of volume-based distribution: 20 ⁇ m * 5 Made by Nissho Kagakusha (ST Starch C (W)): Average particle size 18 ⁇ m * 6
• AGC SAITEC Average particle size 12 ⁇ m * 7
• AGC SAITEC Average particle size 4 ⁇ m * 8
• AGC SAITEC Average particle size 10 ⁇ m * 9 Made by Evonik Operations: Average particle diameter 10 ⁇ m * 10 Average particle diameter 20 ⁇ m, bulk density 0.22 g / cm 3 * 11 Made by Daito Kasei Kogyo Co., Ltd .: Average particle diameter 5 ⁇ m * 12 Made by Daito Kasei Kogyo Co., Ltd .: Average particle diameter 10 ⁇ m *
• Manufacturing Examples 1 to 4 An example of producing the powder composition of the present invention is shown below.
• (Manufacturing Example 1) Weigh 15.0 kg of silica, 7.5 kg of crystalline cellulose, and 2.5 kg of N ⁇ -lauroyl lysine (median diameter of 3.9 ⁇ m in volume-based distribution) using a Henshell mixer (Nippon Coke Industries FM Mixer FM150), and use the mixer as a mixer. Add at the same time (total amount of powder: 25 kg). Mix for 30 minutes at a peripheral speed of 60 m / sec of the stirring blade.
• a presto foundation was prepared and evaluated as a cosmetic or a skin external preparation using the powder composition of the present invention.
• 5 specialized panels gave grades to each of the 4 evaluation items of "adhesiveness”, “smoothness at the time of application”, “non-stickiness”, and “moisturizing feeling”, and based on the average score of 5 people.
• the score of the evaluation item was decided. Further, it was judged on a scale of 5 from A to D based on the average value of the scores of each evaluation item.
• Example 8 A presto foundation was prepared as follows using the components shown in Tables 9-1 and 9-2. B was heated and dissolved. A was weighed and mixed with a lab miller for 30 seconds. B was added to A, and the mixture was further stirred with a laboratory mixer for 5 minutes, and then mixed with a laboratory miller for 30 seconds ⁇ 3 times. It was sieved with a 150 ⁇ m open sieve to make the particle size uniform, filled in a gold plate, and compression-molded.
• Raw materials The raw materials used in each of the Examples and Comparative Examples from Table 9-1 to Table 9-2 are as follows. * 1 SA-Tark JA-46R manufactured by Miyoshi Kasei, Inc.
• Example 9 A presto foundation was prepared as follows using the components shown in Table 10-1 and Table 10-2. B was heated and dissolved. A was weighed and mixed with a lab miller for 30 seconds. B was added to A, and the mixture was further stirred with a laboratory mixer for 5 minutes, and then mixed with a laboratory miller for 30 seconds ⁇ 3 times. It was sieved with a 150 ⁇ m open sieve to make the particle size uniform, filled in a gold plate, and compression-molded. Compared with Comparative Examples 9-1 to 9-4, in Examples 9-1 to 9-10, a formulation having better moldability and excellent removability was obtained.
• Raw materials The raw materials used in each of the Examples and Comparative Examples from Table 10-1 to Table 10-2 are as follows.
• a liquid foundation was prepared and evaluated as a cosmetic or a skin external preparation using the powder composition of the present invention.
• 5 specialized panels gave grades to each of the 4 evaluation items of "adhesiveness”, “smoothness at the time of application”, “non-stickiness”, and “moisturizing feeling", and based on the average score of 5 people.
• the score of the evaluation item was decided. Further, it was judged on a scale of 5 from A to D based on the average value of the scores of each evaluation item.
• Example 10 A liquid foundation was prepared as follows using the components shown in Tables 11-1 and 11-2. A was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. B was added to A, and the mixture was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. Further, C was added to A, and the mixture was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. D was heated to 75 ° C to dissolve, and then gradually added to A for emulsification. After that, it was cooled to 30 ° C while stirring with a paddle. Raw materials: The raw materials used in each of the Examples and Comparative Examples from Table 11-1 to Table 11-2 are as follows.
• Example 11 A liquid foundation was prepared as follows using the components shown in Tables 12-1 and 12-2. A was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. B was added to A, and the mixture was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. Further, C was added to A, and the mixture was heated (75 ° C.) and mixed (4000 rpm) with a homomixer. D was heated to 75 ° C to dissolve, and then gradually added to A for emulsification. After that, it was cooled to 30 ° C while stirring with a paddle. Raw materials: The raw materials used in each of the Examples and Comparative Examples from Table 12-1 to Table 12-2 are as follows.
• a lip cosmetic as a cosmetic using the powder composition of the present invention or a skin external preparation was prepared as follows using the components shown in Table 13.
• Component A was heated and dissolved at 105 ⁇ 5 ° C.
• component B was added to component A and heated and dissolved at 90 ° C.
• component C was added, heated and mixed at 90 ° C., dispersed in three rolls, and then component D was added.
• defoaming was performed. It was filled in a sink at a filling temperature of 90 ° C., cooled, and then loaded into a container.
• the lip cosmetic of Formulation Example 1 had less color unevenness and good color uniformity. Furthermore, there was no sweating and the stability was good.
• a leave-on cosmetic was prepared as follows using the components shown in Table 14. After heating and dissolving each of the component A and the component B at 80 ° C., the component A was added to the component B with stirring. It was emulsified with a homomixer and cooled to room temperature (3000 rpm, 3 minutes, 80 ° C.) to obtain leave-on cosmetics.
• the leave-on cosmetics of Formulation Example 2 had an excellent moist feeling after application, and were glossy when applied. Furthermore, the stability and antiseptic property were good.
• Example 12-1 to 12-7 Each raw material was weighed so as to have a total of 5.0 g at the compounding ratio (mass%) shown in Table 15, and all the raw materials were put into a lab miller (Tescom Mill & Mixer TML162) at the same time. The evaluation sample was a mixture for 100 seconds (20 seconds 5 times, scraping off the powder adhering to the inner wall surface during each mixing).
• Raw materials The raw materials used in each of the examples in Table 15 above are as follows.
• Loose powder was prepared as follows using the components shown in Table 16.
• Component A is mixed and pulverized using a pulverizer.
• Component B is added to component A and stirred and mixed.
• the mixture of component C is added and stirred and mixed.
• a mixture of component D was added, and the mixture was stirred and mixed to obtain a loose powder.
• the loose powders of Formulation Examples 3 to 9 were excellent in slipperiness, adhesiveness, and uniformity during application, and were also excellent in moist feeling and soft focus effect after application.
• Eye makeup cosmetics were prepared as follows using the ingredients shown in Table 17. After mixing the A component for 10 minutes, the B component was added to the A component and further mixed for 20 minutes. The C component was mixed for 10 minutes using a mixer (FM 10C / I manufactured by Nippon Coke Industries, Ltd.), then added to the mixture of A component + B component, and further mixed for 5 minutes. The obtained mixture was filled in a container and compressed using a press to obtain the desired eye makeup cosmetics.
• the eye make-up cosmetic of Formulation Example 4 had good pearly feeling, gloss, shine and color development after application.

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