WO2021106211A1 - Procédé de production de timbre adhésif - Google Patents

Procédé de production de timbre adhésif Download PDF

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Publication number
WO2021106211A1
WO2021106211A1 PCT/JP2019/046845 JP2019046845W WO2021106211A1 WO 2021106211 A1 WO2021106211 A1 WO 2021106211A1 JP 2019046845 W JP2019046845 W JP 2019046845W WO 2021106211 A1 WO2021106211 A1 WO 2021106211A1
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WO
WIPO (PCT)
Prior art keywords
patch
base material
release film
cutting
sheet
Prior art date
Application number
PCT/JP2019/046845
Other languages
English (en)
Japanese (ja)
Inventor
直礼 奥田
裕樹 堀本
立樹 小枝
彰 永松
Original Assignee
小林製薬株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 小林製薬株式会社 filed Critical 小林製薬株式会社
Priority to PCT/JP2019/046845 priority Critical patent/WO2021106211A1/fr
Publication of WO2021106211A1 publication Critical patent/WO2021106211A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10—Cooling bags, e.g. ice-bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
    • B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
    • B26D1/12—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a cutting member moving about an axis
    • B26D1/14—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a cutting member moving about an axis with a circular cutting member, e.g. disc cutter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00—Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/08—Means for treating work or cutting member to facilitate cutting

Definitions

  • the present invention relates to a method for producing a patch to be used by sticking to human skin.
  • the conventional patch 100 has a structure in which an aqueous gel is laminated as an adhesive layer 102 on a supporting base material 101 such as a non-woven fabric and the adhesive layer 102 is covered with a release film 103. Has been done.
  • the conventional patch 100 is a strip-shaped patch sheet in which an adhesive layer is applied on a long support base material and then a long release film is laminated on the surface thereof. , Manufactured by cutting to a predetermined size with a cutting blade.
  • the cutting position of the patch sheet is pressed to extrude and eliminate the adhesive layer at the cut position. It is carried out. This prevents the adhesive layer from being exposed on the end surface (cut surface) of the patch after cutting.
  • the support base material 101 and the release film 103 are not bonded to each other at the outer peripheral edge thereof. Therefore, when a load is applied such that the front surface and / or the back surface of the patch 1 is pressed, the adhesive layer 102 may be pushed out and protrude from the outer peripheral edge of the patch 1, which means that the thickness of the adhesive layer 102 is increased. This becomes a remarkable problem when the size is large or when the adhesive layer 102 has high fluidity. In order to solve this problem, a step of promoting solidification of the adhesive layer 102 is required, which causes an increase in manufacturing cost.
  • the present invention has been made to solve the above problems, and an object of the present invention is to provide a method for producing a patch that can prevent the adhesive layer from sticking out.
  • the present invention relates to a method for producing a patch comprising a supporting base material, an adhesive layer laminated on one surface of the supporting base material, and a release film covering the adhesive layer.
  • a plurality of patches having a support base material, an adhesive layer laminated on one surface of the support base material, and a release film covering the pressure-sensitive adhesive layer are continuously attached in at least one direction.
  • the agent sheet is characterized by including a joining step of joining the supporting base material and the release film at a contour portion serving as an outer peripheral edge of the patch, and a cutting step of cutting the patch sheet at the contour portion. And.
  • the support base material and the release film can be bonded at the contour portion of the patch sheet.
  • the support base material and the release film are bonded at a position separated inward from the contour portion of the patch sheet. Can be done.
  • the supporting base material and the release film are bonded by applying ultrasonic vibration from the release film side by an ultrasonic vibration device.
  • an ultrasonic vibration device Can be configured.
  • the patch sheet is sandwiched between the ultrasonic vibrating device and the cutting blade, and the cutting blade is subjected to ultrasonic vibration by the ultrasonic vibrating device.
  • the ultrasonic vibration device further includes a horn that comes into contact with the patch sheet.
  • the cutting blade can be configured to cut the patch sheet at the contour portion on the contact surface of the horn with respect to the patch sheet.
  • the supporting base material and the release film can be configured to be bonded by heat welding.
  • the supporting base material can be configured to be a non-woven fabric.
  • the non-woven fabric can be configured to contain heat-weldable fibers and the release film is a heat-weldable film, and further, the heat-weldable fibers are polypropylene fibers.
  • the heat-weldable film can be configured to be a polypropylene film.
  • the adhesive layer can be configured to be an aqueous gel, and the water content of the aqueous gel is 60% by weight or more and 95% by weight or less.
  • a base material transporting step of unwinding and transporting a long supporting base material wound on the outer peripheral surface of the base material supply roll in multiple layers.
  • the coating process of applying the adhesive layer to one surface of the long supporting base material to be conveyed, and the long release film wound several times around the outer peripheral surface of the film supply roll are unwound to form the long release film. It can be configured to include a sheet forming step of forming the patch sheet by superimposing it on the adhesive layer of the support base material.
  • the release film and the supporting base material are formed in parallel with the contour portion which is the outer peripheral edge of the patch with respect to the patch sheet before or when the patch sheet is cut. Joining is done around the circumference. Therefore, in the patch after cutting, the supporting base material and the release film are joined along the outer peripheral edges of the respective patches, so that the front surface and / or the back surface of the patch is pressed during transportation or the like to load the patch. Even if it is applied, it is possible to prevent the adhesive layer from being extruded and protruding from the outer peripheral edge of the patch. Further, the step for promoting the solidification of the adhesive layer during the production of the patch can be shortened or omitted.
  • FIG. 1 shows a schematic configuration of a method for producing a patch according to an embodiment of the present invention.
  • the patch produced by the method for producing the patch of the present embodiment is used by being attached to human skin, and for example, cooling the affected area during fever, headache, toothache, inflammation, etc.
  • a sheet-shaped cooling agent used for cooling the heat of a face or the like, or cooling down muscles after sports can be exemplified.
  • the patch 1 includes at least a support base material 2, an aqueous gel 3 as an adhesive layer, and a release film 4, and has a layered structure in which these are laminated. ..
  • the patch 1 is attached to the user's skin due to the adhesiveness of the aqueous gel 3 by peeling the release film 4 from the supporting base material 2 and directly applying the exposed aqueous gel 3 to the part to be cooled on the skin. Attached.
  • the water contained in the aqueous gel 3 evaporates with the passage of time, and the temperature of the aqueous gel 3 is lowered by the heat of vaporization taken at that time, so that the skin in contact with the aqueous gel 3 is cooled.
  • each step of the method for producing the patch according to the present embodiment will be described in order based on FIGS. 1 to 3. It should be noted that the thickness of each component of the patch 1 and the patch sheet 10 is exaggerated in each drawing for easy understanding.
  • a base material transporting step of transporting a long support base material 20 and an aqueous gel 3 as an adhesive layer are applied to one surface of the long support base material 20 to be transported.
  • Each process is provided with a processing device for carrying out the processing in each process.
  • a long support base material 20 wound around the outer peripheral surface of the base material supply roll 11 in multiple layers is unwound from the base material supply roll 11 and up to the support roll 12 with the longitudinal direction thereof as the transfer direction. Transport.
  • the base material supply roll 11 supports a long support base material 20 wound in a roll shape.
  • the long support base material 20 supports the aqueous gel 3 on one surface thereof.
  • the support base material 20 is not formed into a fixed shape, but is in the form of a sheet that can be flexibly deformed.
  • the sheet structure of the support base material 20 is not particularly limited as long as it has moisture permeability and breathability and can support the water-based gel 3, and various woven fabrics, non-woven fabrics, films and the like are used. However, among them, it is preferable to use a non-woven fabric.
  • the materials thereof are natural fibers such as cotton, linen and wool; cellulose fibers such as rayon and acetate; nylon, vinylon, styrene, polypropylene, polyethylene and polyethylene. Examples thereof include synthetic resin fibers such as terephthalate and acrylic; and fibers (blended cotton products and mixed fiber products) in which various fibers are mixed.
  • the support base material 2 is formed of a film, polystyrene (styrene), polypropylene, polyethylene terephthalate, polyethylene and the like can be exemplified as the material thereof.
  • the long support base material 20 can be formed by using various materials described above, and among them, it is made of a non-woven fabric containing synthetic fibers (heat-welding fibers) having heat-welding properties such as polypropylene fibers. Is preferable.
  • the heat-weldable fiber in the support base material 20 when heat or ultrasonic vibration is applied to the support base material 20 and the release film 40 in the joining step described later, the heat-weldable fiber in the support base material 20 is applied. Is melted and integrated with the release film 40 (for example, one made of a heat-weldable film such as a polypropylene film), so that the support base material 20 and the release film 40 can be joined by welding.
  • the long support base material 20 is not limited to one layer, and may be composed of a laminate of two layers or three or more layers.
  • the support base material 20 is preferably a mixed fiber product of, for example, polyethylene terephthalate fibers and heat-weldable fibers.
  • the support base material 20 is preferably made of a laminate in which a layer made of heat-weldable fibers faces the side in contact with the release film 4.
  • the thickness of the long support base material 20 is not particularly limited, but is 0.1 mm or more and 3.0 mm or less from the viewpoint of the usability of the manufactured patch 1 and the ease of fitting to the patch site. It is preferably 0.5 mm or more and 2.0 mm or less.
  • the width of the long support base material 20 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but is preferably a size capable of forming a plurality of individual patches 1 in the width direction. ..
  • the coating device 6 includes a tank 13 for storing the aqueous gel 3, a coating roll 14 for taking out the aqueous gel 3 from the tank 13 and applying it to the long support base material 20, and a coating roll 14 for applying the long support base material 20. It is composed of a support roll 12 sandwiched between the two. A part of the outer peripheral surface of the coating roll 14 is immersed in the water-based gel 3 in the tank 13, and the water-based gel 3 in the tank 13 is adhered to the outer peripheral surface by rotating in the direction of the arrow. Is taken out from the tank 13. Then, the coating roll 14 applies the aqueous gel 3 adhered to the outer peripheral surface to one surface of the long supporting base material 20 supported by the supporting roll 12.
  • Aqueous gel 3 has water-holding property, moisture-releasing property, self-retaining property, etc. in addition to adhesiveness.
  • the "water-holding property” means a property of stably containing water inside, but more preferably a property of not exuding the contained water even when further compressed.
  • self-retaining property means a property of retaining the shape without significantly causing fluidity or disintegration.
  • a natural high molecular weight polysaccharide generally used as a gelling agent can be exemplified.
  • natural gums such as carrageenan, alginic acid, propylene glycol alginate, tara gum, locust bean gum, glucomannan, xanthan gum, gellan gum, pectin, purulan, guar gum, psyllium seed gum, sodium alginate, mannan, gelatin, and agar.
  • Glucomannan and locust bean gum can be preferably exemplified.
  • gelling agent examples include polyacrylic acid, polymethacrylic acid, salts of polyacrylic acid, salts of polymethacrylic acid, and the like, in addition to the above-mentioned natural high molecular weight polysaccharides. These can be used alone or in combination of two or more.
  • Aqueous gel 3 refreshes polyhydric alcohol, surfactant, preservative, preservative, stabilizer, fragrance, colorant, pH adjuster, limonene, camphor, peppermint oil, l-menthol and the like as other components. It may contain known additives such as agents, moisturizers, stimulants, disinfectants, antibacterial agents, pressure-imparting agents, shape-retaining agents, and thickeners.
  • the water-based gel 3 preferably contains a sufficient amount of water in order to continuously exert a desired cooling power, and the water content of the water-based gel 3 is determined in the composition constituting the water-based gel 3. , 60% by weight or more, more preferably 70% by weight or more. Further, the upper limit of the water content of the aqueous gel 3 is preferably 95% by weight or less, more preferably 90% by weight or less, from the viewpoint of self-retaining property.
  • the thickness of the aqueous gel 3 is not particularly limited, but is preferably moderately large from the viewpoints of cooling power, feel when attached to the skin, maintenance of the attached state to the skin, and the like.
  • the patch 1 after manufacture as shown in FIG. 6, the thickness D C of the aqueous gel 3 at the center of the supporting substrate 2 is preferably 0.1mm or more 20mm or less, and less than 1.0mm 10mm or less Is more preferable.
  • the thickness of the aqueous gel 3 is preferably uniform or substantially uniform over the entire area of the supporting substrate 2, almost the thickness D E of the aqueous gel 3 in the vicinity of the thickness D C and the outer peripheral edge of the aqueous gel 3 in the central it is no difference (D E ⁇ D C) is preferred.
  • the thickness of the water-based gel 3 does not necessarily have to be uniform or almost uniform over the entire area of the support base material 2, and although not shown, the center of the support base material 2 is closer to the center of the support base material 2 than the vicinity of the outer peripheral edge. may be large thickness of (D C> D E), towards the vicinity of the outer peripheral edge than the center of the supporting substrate 2 may be larger thickness aqueous gel 3 (D E> D C) .
  • the thickness of the aqueous gel 3 gradually decreases or gradually increases toward the outer peripheral edge of the supporting base material 2, or only the portion close to the outer peripheral edge of the supporting base material 2 becomes toward the outer peripheral edge. It may be gradually reduced or gradually increased.
  • the thickness of the aqueous gel 3, for example, the ratio D E / D C of the supporting substrate 2 of the joint 5 from 1.0mm inner thickness D E to the thickness D C at the center of the supporting substrate 2 is 0.1 or more 2 It is preferably 0.0 or less, more preferably 0.3 or more and 1.2 or less, and further preferably 0.5 or more and 1.0 or less.
  • the thickness of the aqueous gel 3 can be measured by using the method described in "6.1 Thickness (ISO method)" of JIS L1913: 2010.
  • the long release film 40 wound in multiple layers on the outer peripheral surface of the film supply roll 15 is unwound and the bonding roll is bonded with its longitudinal direction as the transport direction. Transport up to 16.
  • the film supply roll 15 supports a long release film 40 wound in a roll shape.
  • the long release film 40 to be conveyed is bonded to the long support base material 20 on which the water-based gel 3 is laminated by the bonding device 7 to form a patch sheet 10.
  • the bonding device 7 is composed of a support roll 12 and a bonding roll 16, and both rolls 12 are in a state where the long release film 40 is superposed on the aqueous gel 3 of the long support base material 20.
  • the patch sheet 10 is formed after adjusting the thickness of the aqueous gel 3 laminated on the long support base material 20 to a predetermined thickness by passing between 16.
  • the formed patch sheet 10 is conveyed to the cutting device 8 in the next step by a transfer roll 17 and a transfer conveyor 18 such as a belt conveyor.
  • the material of the long release film 40 is not particularly limited as long as it can coat the aqueous gel 3, and examples thereof include synthetic resins such as polypropylene, polyethylene, polyester, nylon, vinyl chloride, and polyethylene terephthalate. be able to.
  • the release film 40 it is preferable to use a film having heat welding properties (heat welding film) such as a polyolefin resin film (for example, polypropylene film, polyethylene film, etc.).
  • the long supporting base material 20 and the release film 40 are preferably formed using the same material, and particularly preferably polypropylene, from the viewpoint of facilitating heat welding and ultrasonic welding.
  • the thickness of the long release film 40 is not particularly limited, and can be, for example, 0.02 mm or more and 0.3 mm or less, and more preferably 0.03 mm or more and 0.2 mm or less.
  • the width of the long release film 40 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but like the long support base material 20, a plurality of individual patches 1 are applied in the width direction. It is preferably a size that can be formed.
  • the support base material 20 and the release film 40 are joined to the patch sheet 10 conveyed by the transfer conveyor 18 by the ultrasonic vibration device 9.
  • the support base material 20 and the release film 40 are joined in a shape parallel to the contour portion which is the outer peripheral edge of the patch 1 on the patch sheet 10, and are performed around the contour portion.
  • the support base material 20 and the release film 40 may be joined at the position of the contour portion of the patch 1 on the patch sheet 10 over the entire circumference along the contour portion, or the patch on the patch sheet 10. It may be performed around the contour portion at a position separated inward from the contour portion of 1.
  • the support base material 20 and the release film 40 are joined at the position of the contour portion of the patch 1 on the patch sheet 10 along the contour portion.
  • the patch sheet 10 has a plurality of patches 1 continuous in at least one direction (longitudinal direction) and a plurality of patches 1 in the other direction (width direction) orthogonal to the one direction. From the above, the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the other direction (width direction) and the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the one direction (longitudinal direction). The support base material 20 and the release film 40 are joined to the cutting line L2).
  • the support base material 20 and the release film 40 are joined at the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is lined up in the other direction (width direction).
  • the first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B are arranged on the release film 40 side with respect to the patch sheet 10.
  • the first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B are provided with horns 90 and 91 having contact surfaces 90A and 91A with respect to the patch sheet 10 as ultrasonic transmitting parts, respectively, and an oscillator (shown in the figure).
  • an AC voltage is supplied to the piezoelectric vibrator, ultrasonic vibration is generated and the horns 90 and 91 vibrate at high speed.
  • the first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B approach and separate from the patch sheet 10 by the first moving mechanism (not shown) and the second moving mechanism (not shown), respectively.
  • the contact surfaces 90A and 91A of the horns 90 and 91 come into contact with the patch sheet 10 along the cutting lines L1 and L2.
  • ultrasonic vibration acts on the release film 40 of the patch sheet 10 along the cutting lines L1 and L2 by the horns 90 and 91.
  • the release film 40 and the support base material 20 are welded along the cutting lines L1 and L2, and the release film 40 and the support base material 20 are formed at the contour portion which is the outer peripheral edge of the patch 1. Are joined.
  • the patch sheet 10 is sandwiched between the ultrasonic vibrating device 9 and the cutting blade of the cutting device 8, and the patch sheet 10 is sandwiched by the ultrasonic vibrating device 9.
  • the cutting step of cutting the patch sheet 10 with the cutting blade of the cutting device 8 is performed at the same time while applying ultrasonic vibration to the surface.
  • the cutting device 8 corresponds to the first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B of the ultrasonic vibration device 9, respectively, and the patch sheet 10 is arranged in the other direction (width direction) of the patch 1.
  • the first cutting device 8A that cuts at the boundary portion (cutting line L1) and the second cutting device 8B that cuts the patch sheet 10 at the boundary portion (cutting line L2) of the patches 1 that are lined up in the one direction (longitudinal direction). And have.
  • the first cutting device 8A and the second cutting device 8B are arranged on the support base material 20 side with respect to the patch sheet 10.
  • the first cutting device 8A includes a plurality of cutting blades 80 provided at intervals in the width direction of the patch sheet 10, and a rotation drive mechanism (rotating) for making each cutting blade 80 rotatable. (Not shown).
  • the first cutting device 8A is arranged so that each cutting blade 80 faces each horn 90 of the first ultrasonic vibration device 9A with the patch sheet 10 interposed therebetween.
  • Each cutting blade 80 is, for example, a rotary blade having a disk shape and a cutting edge having a substantially V-shaped cross section, and is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting blade is conveyed.
  • each cutting blade 80 is arranged so that the cutting edge abuts along a plurality of parallel cutting lines L1 extending in the longitudinal direction with respect to the patch sheet 10 wider than the patch 1.
  • each cutting blade 80 sandwiches the patch sheet 10 with each horn 90, so that a wide patch can be attached at each cutting line L1. Cut the agent sheet 10.
  • the patch sheet 10 is divided into the same width as the patch 1.
  • the cutting blade 80 does not necessarily have to be a rotary blade as in the present embodiment.
  • the second cutting device 8B includes a cutting blade 81 whose cutting edge has a substantially V-shaped cross section.
  • the second cutting device 8B is arranged such that the cutting blade 81 faces the horn 91 of the second ultrasonic vibrating device 9B with the patch sheet 10 interposed therebetween.
  • the cutting blade 81 is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting edge is conveyed, and the cutting edge is arranged along the width direction of the patch 10.
  • the cutting blade 81 sandwiches the patch sheet 10 with the horn 91 when the second ultrasonic vibration device 9B approaches the patch sheet 10, so that the patch is longer than the patch 1.
  • the patch sheet 10 is sequentially cut at each cutting line L2 at a predetermined interval along the longitudinal direction with respect to the sheet 10. As a result, the patch sheet 10 is divided into a plurality of patch 1.
  • the patch sheet 10 is sandwiched between the horns 90 and 91 and the cutting blades 80 and 81, and each of the horns 90 and 91 cuts the patch sheet 10 while applying ultrasonic vibration to the patch sheet 10.
  • the water-based gel 3 is released to the cutting blades 80 at the time of cutting. Since it does not adhere to, 81, the patch sheet 10 can be cut with high accuracy.
  • the release film 40 of the patch sheet 10 is cut at the cutting lines L1 and L2.
  • the release film 40 and the support base material 20 are welded together to bond the release film 40 and the support base material 20. Therefore, with respect to the patch 1 after cutting, as shown in FIGS. 5 and 6, the outer peripheral edges of the support base material 2 and the release film 4 can be bonded over the entire circumference, and the aqueous gel 3 can be bonded to the support base material 2 and the support base material 2. It can be sealed inside the release film 4.
  • the support base material 20 is made of polyethylene terephthalate fiber and a non-woven fabric made of polypropylene fiber
  • the release film 40 is made of polypropylene film. Is preferable.
  • each of the cutting blades 80 and 81 when the cutting edge of each of the cutting blades 80 and 81 has a small cutting edge angle ⁇ and a sharp tip, it becomes easier to cut the patch sheet 10, while supporting the manufactured patch 1.
  • the bond between the base material 2 and the release film 4 becomes weak.
  • the cutting edge angle ⁇ is appropriately set in order to achieve both the ease of cutting the patch sheet 10 and the bonding strength of the supporting base material 2 and the release film 4.
  • the cutting edges of the cutting blades 80 and 81 do not necessarily have to be sharpened, and may have a flat portion having a predetermined width at the tip as shown in FIG. 4 (B).
  • the patch 1 individually cut from the patch sheet 10 by the cutting step is transported to the next step by the transport conveyor 19 arranged at the lower position in the vertical direction.
  • the patch 1 is manually or mechanically packed in a non-breathable storage bag, and in the subsequent step, a treatment for solidifying the aqueous gel 3 is performed, so that the patch 1 is formed. Is manufactured.
  • a patch sheet 10 in which a plurality of patches 1 are continuous in at least one direction is placed in parallel with a contour portion which is an outer peripheral edge of the patch 1 and is supported by the support base material 20.
  • the release film 40 all around and cutting at the contour portion, in the patch 1 after cutting, as shown in FIGS. 5 and 6, the support base material 2 and the release film 4 A joint portion 5 is formed along the outer peripheral edge, and the aqueous gel 3 is enclosed in the support base material 2 and the release film 4. Therefore, even if the aqueous gel 3 has a high water content and high fluidity, it is possible to prevent the aqueous gel 3 from leaking from the outer peripheral edge of the patch 1 during line transportation of the patch 1 after cutting. ..
  • the joint portion 5 of the support base material 2 and the release film 4 in the patch 1 after cutting may have a slightly large band shape as shown in FIG. 6 or a small band shape as shown in FIG. 7. Although it may be streaky, the smaller the width W of the joint portion 5, the wider the aqueous gel 3 can be laminated closer to the outer peripheral edge of the supporting base material 2, which is preferable.
  • By laminating the aqueous gel 3 on almost the entire area of the supporting base material 2 with a sufficient thickness it is possible to increase the range of the skin on which the desired cooling force can be exerted by the patch 1.
  • the outer peripheral edge of the supporting base material 2 adheres well to the skin due to the adhesiveness of the aqueous gel 3, and the outer peripheral edge of the supporting base material 2 is less likely to roll up, so that the patch 1 can be easily peeled off from the skin. It can be suppressed.
  • the width W of the joint portion 5 is preferably 2.0 mm or less, more preferably 1.0 mm or less, and further preferably 0.5 mm or less. Further, the lower limit of the width W of the joint portion 5 is preferably 0.05 mm or more, more preferably 0.1 mm or more, and 0. It is more preferably 2 mm or more.
  • the water-based gel 3 is pressed by pressing the front surface and / or the back surface of the patch 1 during transportation or storage of the patch 1, the water-based gel 3 is extruded to the outside of the patch 1. It is possible to prevent it from sticking out from the peripheral edge. This makes it possible to prevent the aqueous gel 3 from adhering to the user's hand when the user uses the patch 1.
  • the patch 1 since the patch 1 is stored in a packaging box (not shown) in a state of being stacked in a plurality of layers during transportation, storage, etc., the patch 1 bears the weight of the other plurality of patches 1.
  • the aqueous gel 3 Upon receiving, the aqueous gel 3 is compressed. Conventionally, since the aqueous gel 3 may be pressed and protrude from the outer peripheral edge of the patch 1, a partition is set in the packaging box, and the weight of the patch 1 is received by the partition to receive the weight of the patch 1, and the aqueous gel 3 is used. Was prevented from being squeezed.
  • the manufactured patch 1 is attached even if the aqueous gel 3 is pressed by the weight of a plurality of other patches 1 in the packaging box. Since it does not protrude from the outer peripheral edge of the agent 1, a partition is not required, and the cost can be reduced accordingly.
  • the support base material 20 and the release film 40 are joined and cut at the same time with respect to the patch sheet 10, so that the production efficiency of the patch 1 is reduced by shortening the process time. Can be improved.
  • the horns 90 and 91 of the ultrasonic vibration devices 9A and 9B are brought into contact with the patch sheet 10, and the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are brought into contact with each other. Since the patch sheet 10 is cut on the contact surfaces 90A and 91A by pressing against the horns 90 and 91, the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are pressed to cut the patch sheet 10. It is possible to eliminate the need for a backing plate for the purpose.
  • the water-based gel 3 does not leak from the outer peripheral edge of the patch 1 even if the water-based gel 3 has a high water content and high fluidity. Therefore, the processing time of the treatment step for solidifying the aqueous gel 3 after the cutting step of the patch sheet 10 described above can be shortened or this treatment step can be eliminated. The manufacturing efficiency can be improved.
  • the joining step and the cutting step are performed at the same time, but the cutting may be performed after the supporting base material 20 and the release film 40 are bonded to the patch sheet 10.
  • the patch sheet 10 has a contour portion that becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions of the cutting lines L1 and L2 shown in FIG.
  • the supporting base material 20 and the release film 40 are joined together.
  • the patch sheet 10 becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions on both sides of the cutting lines L1 and L2 shown in FIG.
  • the supporting base material 20 and the release film 40 may be joined at a position inside from the contour portion, and may be cut into individual patches 1 at the respective cutting lines L1 and L2. At this time, as shown in FIG.
  • the patch 1 after cutting is joined by the joining portion 5 at a position P2 separated inward from the position P1 of the outer peripheral edge of each of the supporting base material 2 and the release film 4. Since the position P2 of the joint portion 5 is separated inward from the position P1 of the outer peripheral edge of the support base material 2 and the release film 4, the outer peripheral edge of the release film 4 is not bonded to the support base material 2 by the joint portion 5.
  • the release film 4 can be easily peeled off from the support base material 2.
  • the distance of the position P2 from the position P1 is not particularly limited, but is preferably 1.0 mm or more and 2.0 mm or less.
  • the release film 4 can be easily peeled off from the support base material 2, and the aqueous gel 3 can be laminated over a wide range closer to the outer peripheral edge of the support base material 2.
  • the release film 4 and the support base material 2 do not have to be attached to each other between the position P2 and the position P1.
  • the joint portion is formed by the adhesiveness of the aqueous gel 3 slightly existing on the support base material 2. It may be attached with a force weaker than 5.
  • the support base material 20 and the release film 40 are joined to the patch sheet 10 by ultrasonic welding with ultrasonic vibration devices 9A and 9B, but the support base material 20 and the release film 40 are welded.
  • the method is not particularly limited as long as at least one of the support base material 20 and the release film 40 is joined by melting, and the support base material 2 and the release film 4 are overlapped with each other.
  • Various known methods such as heat welding (heat sealing) that pressurize both while applying heat in the state can be used. For example, by hot-pressing the patch sheet 10 along the respective cutting lines L1 and L2 using a pair of upper and lower thermal pressure rolls or a press mold (not shown), the support base material 20 and the release film 40 are heat-welded (not shown). It can be joined by heat sealing).
  • the patch sheet 10 has a size in which a plurality of patches 1 are continuous in both the longitudinal direction and the width direction, but a plurality of patches 1 are continuous only in the longitudinal direction. It may be of a size.
  • the patch 1 has a rectangular shape in a plan view, but may have another shape such as a square shape or a substantially elliptical shape.
  • the patch 1 has a three-layer structure of the support base material 2, the aqueous gel 3, and the release film 4, but may have other layers.
  • the coating device 6 for applying the aqueous gel 3 to one surface of the long support base material 20, the bonding device 7 for bonding the long support base material 20 and the release film 40, and the patch sheet 10 are cut.
  • the cutting devices 8A and 8B are not necessarily limited to the devices of the above-described embodiment, and other known devices can be used.
  • the patch 1 is a sheet-shaped coolant and the adhesive layer is an aqueous gel 3, but the patch is particularly applicable as long as it is used by sticking it on human skin.
  • the adhesive layer is not limited, and may be an adhesive other than the aqueous gel 3 as long as it has an adhesive property that allows the supporting base material 2 to be attached to human skin.
  • Patch sheet 1 Patch 2 Supporting base material 3 Aqueous gel (adhesive layer) 4 Release film 8 Cutting device 9 Ultrasonic vibration device 10 Patch sheet 11 Base material supply roll 15 Film supply roll 20 Long support base material 40 Long release film 90,91 Horn

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Abstract

La présente invention concerne un procédé de production d'un timbre adhésif, ledit procédé étant apte à empêcher la saillie d'une couche adhésive. Un procédé de production d'un timbre adhésif selon la présente invention comprend : une étape de liaison dans laquelle une feuille de timbres adhésifs (10), dans laquelle une pluralité de timbres adhésifs (1) sont disposés successivement au moins dans une direction, chacun desdits timbres adhésifs (1) comprenant un matériau de base de support (2), un gel aqueux (3) (une couche adhésive) qui est superposé sur une surface du matériau de base de support (2) et un film de libération (4) qui recouvre le gel aqueux (3), est soumise à la liaison d'un matériau de base de support (20) et d'un film de libération (40) le long de la totalité de la partie contour qui est la périphérie externe de chaque timbre adhésif (1) ; et une étape de coupe dans laquelle la feuille de timbres adhésifs (10) est découpée dans la partie contour.
PCT/JP2019/046845 2019-11-29 2019-11-29 Procédé de production de timbre adhésif WO2021106211A1 (fr)

Priority Applications (1)

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PCT/JP2019/046845 WO2021106211A1 (fr) 2019-11-29 2019-11-29 Procédé de production de timbre adhésif

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PCT/JP2019/046845 WO2021106211A1 (fr) 2019-11-29 2019-11-29 Procédé de production de timbre adhésif

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10235131A (ja) * 1997-02-26 1998-09-08 Toppan Printing Co Ltd シート状脱酸素剤とその切断方法
JP2004201703A (ja) * 2002-11-06 2004-07-22 Akatsuki Kinzoku Kogyo:Kk 貼付剤シートの加工ライン
JP2005237571A (ja) * 2004-02-25 2005-09-08 Terumo Corp 創傷保護用冷却シート
JP2005304717A (ja) * 2004-04-20 2005-11-04 Life Kea Giken Kk 冷却性シートとその製造方法
JP2008119837A (ja) * 2006-11-08 2008-05-29 Kiwa Kinzoku:Kk 超音波溶着装置
JP2010188056A (ja) * 2009-02-20 2010-09-02 Medorekkusu:Kk 薬液貼付用ドレッシング製剤

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10235131A (ja) * 1997-02-26 1998-09-08 Toppan Printing Co Ltd シート状脱酸素剤とその切断方法
JP2004201703A (ja) * 2002-11-06 2004-07-22 Akatsuki Kinzoku Kogyo:Kk 貼付剤シートの加工ライン
JP2005237571A (ja) * 2004-02-25 2005-09-08 Terumo Corp 創傷保護用冷却シート
JP2005304717A (ja) * 2004-04-20 2005-11-04 Life Kea Giken Kk 冷却性シートとその製造方法
JP2008119837A (ja) * 2006-11-08 2008-05-29 Kiwa Kinzoku:Kk 超音波溶着装置
JP2010188056A (ja) * 2009-02-20 2010-09-02 Medorekkusu:Kk 薬液貼付用ドレッシング製剤

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