WO2021106211A1 - Method for producing adhesive patch - Google Patents

Method for producing adhesive patch Download PDF

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Publication number
WO2021106211A1
WO2021106211A1 PCT/JP2019/046845 JP2019046845W WO2021106211A1 WO 2021106211 A1 WO2021106211 A1 WO 2021106211A1 JP 2019046845 W JP2019046845 W JP 2019046845W WO 2021106211 A1 WO2021106211 A1 WO 2021106211A1
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WO
WIPO (PCT)
Prior art keywords
patch
base material
release film
cutting
sheet
Prior art date
Application number
PCT/JP2019/046845
Other languages
French (fr)
Japanese (ja)
Inventor
直礼 奥田
裕樹 堀本
立樹 小枝
彰 永松
Original Assignee
小林製薬株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 小林製薬株式会社 filed Critical 小林製薬株式会社
Priority to PCT/JP2019/046845 priority Critical patent/WO2021106211A1/en
Publication of WO2021106211A1 publication Critical patent/WO2021106211A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/10—Cooling bags, e.g. ice-bags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D1/00—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor
    • B26D1/01—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work
    • B26D1/12—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a cutting member moving about an axis
    • B26D1/14—Cutting through work characterised by the nature or movement of the cutting member or particular materials not otherwise provided for; Apparatus or machines therefor; Cutting members therefor involving a cutting member which does not travel with the work having a cutting member moving about an axis with a circular cutting member, e.g. disc cutter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D3/00—Cutting work characterised by the nature of the cut made; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B26—HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
    • B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
    • B26D7/08—Means for treating work or cutting member to facilitate cutting

Definitions

  • the present invention relates to a method for producing a patch to be used by sticking to human skin.
  • the conventional patch 100 has a structure in which an aqueous gel is laminated as an adhesive layer 102 on a supporting base material 101 such as a non-woven fabric and the adhesive layer 102 is covered with a release film 103. Has been done.
  • the conventional patch 100 is a strip-shaped patch sheet in which an adhesive layer is applied on a long support base material and then a long release film is laminated on the surface thereof. , Manufactured by cutting to a predetermined size with a cutting blade.
  • the cutting position of the patch sheet is pressed to extrude and eliminate the adhesive layer at the cut position. It is carried out. This prevents the adhesive layer from being exposed on the end surface (cut surface) of the patch after cutting.
  • the support base material 101 and the release film 103 are not bonded to each other at the outer peripheral edge thereof. Therefore, when a load is applied such that the front surface and / or the back surface of the patch 1 is pressed, the adhesive layer 102 may be pushed out and protrude from the outer peripheral edge of the patch 1, which means that the thickness of the adhesive layer 102 is increased. This becomes a remarkable problem when the size is large or when the adhesive layer 102 has high fluidity. In order to solve this problem, a step of promoting solidification of the adhesive layer 102 is required, which causes an increase in manufacturing cost.
  • the present invention has been made to solve the above problems, and an object of the present invention is to provide a method for producing a patch that can prevent the adhesive layer from sticking out.
  • the present invention relates to a method for producing a patch comprising a supporting base material, an adhesive layer laminated on one surface of the supporting base material, and a release film covering the adhesive layer.
  • a plurality of patches having a support base material, an adhesive layer laminated on one surface of the support base material, and a release film covering the pressure-sensitive adhesive layer are continuously attached in at least one direction.
  • the agent sheet is characterized by including a joining step of joining the supporting base material and the release film at a contour portion serving as an outer peripheral edge of the patch, and a cutting step of cutting the patch sheet at the contour portion. And.
  • the support base material and the release film can be bonded at the contour portion of the patch sheet.
  • the support base material and the release film are bonded at a position separated inward from the contour portion of the patch sheet. Can be done.
  • the supporting base material and the release film are bonded by applying ultrasonic vibration from the release film side by an ultrasonic vibration device.
  • an ultrasonic vibration device Can be configured.
  • the patch sheet is sandwiched between the ultrasonic vibrating device and the cutting blade, and the cutting blade is subjected to ultrasonic vibration by the ultrasonic vibrating device.
  • the ultrasonic vibration device further includes a horn that comes into contact with the patch sheet.
  • the cutting blade can be configured to cut the patch sheet at the contour portion on the contact surface of the horn with respect to the patch sheet.
  • the supporting base material and the release film can be configured to be bonded by heat welding.
  • the supporting base material can be configured to be a non-woven fabric.
  • the non-woven fabric can be configured to contain heat-weldable fibers and the release film is a heat-weldable film, and further, the heat-weldable fibers are polypropylene fibers.
  • the heat-weldable film can be configured to be a polypropylene film.
  • the adhesive layer can be configured to be an aqueous gel, and the water content of the aqueous gel is 60% by weight or more and 95% by weight or less.
  • a base material transporting step of unwinding and transporting a long supporting base material wound on the outer peripheral surface of the base material supply roll in multiple layers.
  • the coating process of applying the adhesive layer to one surface of the long supporting base material to be conveyed, and the long release film wound several times around the outer peripheral surface of the film supply roll are unwound to form the long release film. It can be configured to include a sheet forming step of forming the patch sheet by superimposing it on the adhesive layer of the support base material.
  • the release film and the supporting base material are formed in parallel with the contour portion which is the outer peripheral edge of the patch with respect to the patch sheet before or when the patch sheet is cut. Joining is done around the circumference. Therefore, in the patch after cutting, the supporting base material and the release film are joined along the outer peripheral edges of the respective patches, so that the front surface and / or the back surface of the patch is pressed during transportation or the like to load the patch. Even if it is applied, it is possible to prevent the adhesive layer from being extruded and protruding from the outer peripheral edge of the patch. Further, the step for promoting the solidification of the adhesive layer during the production of the patch can be shortened or omitted.
  • FIG. 1 shows a schematic configuration of a method for producing a patch according to an embodiment of the present invention.
  • the patch produced by the method for producing the patch of the present embodiment is used by being attached to human skin, and for example, cooling the affected area during fever, headache, toothache, inflammation, etc.
  • a sheet-shaped cooling agent used for cooling the heat of a face or the like, or cooling down muscles after sports can be exemplified.
  • the patch 1 includes at least a support base material 2, an aqueous gel 3 as an adhesive layer, and a release film 4, and has a layered structure in which these are laminated. ..
  • the patch 1 is attached to the user's skin due to the adhesiveness of the aqueous gel 3 by peeling the release film 4 from the supporting base material 2 and directly applying the exposed aqueous gel 3 to the part to be cooled on the skin. Attached.
  • the water contained in the aqueous gel 3 evaporates with the passage of time, and the temperature of the aqueous gel 3 is lowered by the heat of vaporization taken at that time, so that the skin in contact with the aqueous gel 3 is cooled.
  • each step of the method for producing the patch according to the present embodiment will be described in order based on FIGS. 1 to 3. It should be noted that the thickness of each component of the patch 1 and the patch sheet 10 is exaggerated in each drawing for easy understanding.
  • a base material transporting step of transporting a long support base material 20 and an aqueous gel 3 as an adhesive layer are applied to one surface of the long support base material 20 to be transported.
  • Each process is provided with a processing device for carrying out the processing in each process.
  • a long support base material 20 wound around the outer peripheral surface of the base material supply roll 11 in multiple layers is unwound from the base material supply roll 11 and up to the support roll 12 with the longitudinal direction thereof as the transfer direction. Transport.
  • the base material supply roll 11 supports a long support base material 20 wound in a roll shape.
  • the long support base material 20 supports the aqueous gel 3 on one surface thereof.
  • the support base material 20 is not formed into a fixed shape, but is in the form of a sheet that can be flexibly deformed.
  • the sheet structure of the support base material 20 is not particularly limited as long as it has moisture permeability and breathability and can support the water-based gel 3, and various woven fabrics, non-woven fabrics, films and the like are used. However, among them, it is preferable to use a non-woven fabric.
  • the materials thereof are natural fibers such as cotton, linen and wool; cellulose fibers such as rayon and acetate; nylon, vinylon, styrene, polypropylene, polyethylene and polyethylene. Examples thereof include synthetic resin fibers such as terephthalate and acrylic; and fibers (blended cotton products and mixed fiber products) in which various fibers are mixed.
  • the support base material 2 is formed of a film, polystyrene (styrene), polypropylene, polyethylene terephthalate, polyethylene and the like can be exemplified as the material thereof.
  • the long support base material 20 can be formed by using various materials described above, and among them, it is made of a non-woven fabric containing synthetic fibers (heat-welding fibers) having heat-welding properties such as polypropylene fibers. Is preferable.
  • the heat-weldable fiber in the support base material 20 when heat or ultrasonic vibration is applied to the support base material 20 and the release film 40 in the joining step described later, the heat-weldable fiber in the support base material 20 is applied. Is melted and integrated with the release film 40 (for example, one made of a heat-weldable film such as a polypropylene film), so that the support base material 20 and the release film 40 can be joined by welding.
  • the long support base material 20 is not limited to one layer, and may be composed of a laminate of two layers or three or more layers.
  • the support base material 20 is preferably a mixed fiber product of, for example, polyethylene terephthalate fibers and heat-weldable fibers.
  • the support base material 20 is preferably made of a laminate in which a layer made of heat-weldable fibers faces the side in contact with the release film 4.
  • the thickness of the long support base material 20 is not particularly limited, but is 0.1 mm or more and 3.0 mm or less from the viewpoint of the usability of the manufactured patch 1 and the ease of fitting to the patch site. It is preferably 0.5 mm or more and 2.0 mm or less.
  • the width of the long support base material 20 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but is preferably a size capable of forming a plurality of individual patches 1 in the width direction. ..
  • the coating device 6 includes a tank 13 for storing the aqueous gel 3, a coating roll 14 for taking out the aqueous gel 3 from the tank 13 and applying it to the long support base material 20, and a coating roll 14 for applying the long support base material 20. It is composed of a support roll 12 sandwiched between the two. A part of the outer peripheral surface of the coating roll 14 is immersed in the water-based gel 3 in the tank 13, and the water-based gel 3 in the tank 13 is adhered to the outer peripheral surface by rotating in the direction of the arrow. Is taken out from the tank 13. Then, the coating roll 14 applies the aqueous gel 3 adhered to the outer peripheral surface to one surface of the long supporting base material 20 supported by the supporting roll 12.
  • Aqueous gel 3 has water-holding property, moisture-releasing property, self-retaining property, etc. in addition to adhesiveness.
  • the "water-holding property” means a property of stably containing water inside, but more preferably a property of not exuding the contained water even when further compressed.
  • self-retaining property means a property of retaining the shape without significantly causing fluidity or disintegration.
  • a natural high molecular weight polysaccharide generally used as a gelling agent can be exemplified.
  • natural gums such as carrageenan, alginic acid, propylene glycol alginate, tara gum, locust bean gum, glucomannan, xanthan gum, gellan gum, pectin, purulan, guar gum, psyllium seed gum, sodium alginate, mannan, gelatin, and agar.
  • Glucomannan and locust bean gum can be preferably exemplified.
  • gelling agent examples include polyacrylic acid, polymethacrylic acid, salts of polyacrylic acid, salts of polymethacrylic acid, and the like, in addition to the above-mentioned natural high molecular weight polysaccharides. These can be used alone or in combination of two or more.
  • Aqueous gel 3 refreshes polyhydric alcohol, surfactant, preservative, preservative, stabilizer, fragrance, colorant, pH adjuster, limonene, camphor, peppermint oil, l-menthol and the like as other components. It may contain known additives such as agents, moisturizers, stimulants, disinfectants, antibacterial agents, pressure-imparting agents, shape-retaining agents, and thickeners.
  • the water-based gel 3 preferably contains a sufficient amount of water in order to continuously exert a desired cooling power, and the water content of the water-based gel 3 is determined in the composition constituting the water-based gel 3. , 60% by weight or more, more preferably 70% by weight or more. Further, the upper limit of the water content of the aqueous gel 3 is preferably 95% by weight or less, more preferably 90% by weight or less, from the viewpoint of self-retaining property.
  • the thickness of the aqueous gel 3 is not particularly limited, but is preferably moderately large from the viewpoints of cooling power, feel when attached to the skin, maintenance of the attached state to the skin, and the like.
  • the patch 1 after manufacture as shown in FIG. 6, the thickness D C of the aqueous gel 3 at the center of the supporting substrate 2 is preferably 0.1mm or more 20mm or less, and less than 1.0mm 10mm or less Is more preferable.
  • the thickness of the aqueous gel 3 is preferably uniform or substantially uniform over the entire area of the supporting substrate 2, almost the thickness D E of the aqueous gel 3 in the vicinity of the thickness D C and the outer peripheral edge of the aqueous gel 3 in the central it is no difference (D E ⁇ D C) is preferred.
  • the thickness of the water-based gel 3 does not necessarily have to be uniform or almost uniform over the entire area of the support base material 2, and although not shown, the center of the support base material 2 is closer to the center of the support base material 2 than the vicinity of the outer peripheral edge. may be large thickness of (D C> D E), towards the vicinity of the outer peripheral edge than the center of the supporting substrate 2 may be larger thickness aqueous gel 3 (D E> D C) .
  • the thickness of the aqueous gel 3 gradually decreases or gradually increases toward the outer peripheral edge of the supporting base material 2, or only the portion close to the outer peripheral edge of the supporting base material 2 becomes toward the outer peripheral edge. It may be gradually reduced or gradually increased.
  • the thickness of the aqueous gel 3, for example, the ratio D E / D C of the supporting substrate 2 of the joint 5 from 1.0mm inner thickness D E to the thickness D C at the center of the supporting substrate 2 is 0.1 or more 2 It is preferably 0.0 or less, more preferably 0.3 or more and 1.2 or less, and further preferably 0.5 or more and 1.0 or less.
  • the thickness of the aqueous gel 3 can be measured by using the method described in "6.1 Thickness (ISO method)" of JIS L1913: 2010.
  • the long release film 40 wound in multiple layers on the outer peripheral surface of the film supply roll 15 is unwound and the bonding roll is bonded with its longitudinal direction as the transport direction. Transport up to 16.
  • the film supply roll 15 supports a long release film 40 wound in a roll shape.
  • the long release film 40 to be conveyed is bonded to the long support base material 20 on which the water-based gel 3 is laminated by the bonding device 7 to form a patch sheet 10.
  • the bonding device 7 is composed of a support roll 12 and a bonding roll 16, and both rolls 12 are in a state where the long release film 40 is superposed on the aqueous gel 3 of the long support base material 20.
  • the patch sheet 10 is formed after adjusting the thickness of the aqueous gel 3 laminated on the long support base material 20 to a predetermined thickness by passing between 16.
  • the formed patch sheet 10 is conveyed to the cutting device 8 in the next step by a transfer roll 17 and a transfer conveyor 18 such as a belt conveyor.
  • the material of the long release film 40 is not particularly limited as long as it can coat the aqueous gel 3, and examples thereof include synthetic resins such as polypropylene, polyethylene, polyester, nylon, vinyl chloride, and polyethylene terephthalate. be able to.
  • the release film 40 it is preferable to use a film having heat welding properties (heat welding film) such as a polyolefin resin film (for example, polypropylene film, polyethylene film, etc.).
  • the long supporting base material 20 and the release film 40 are preferably formed using the same material, and particularly preferably polypropylene, from the viewpoint of facilitating heat welding and ultrasonic welding.
  • the thickness of the long release film 40 is not particularly limited, and can be, for example, 0.02 mm or more and 0.3 mm or less, and more preferably 0.03 mm or more and 0.2 mm or less.
  • the width of the long release film 40 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but like the long support base material 20, a plurality of individual patches 1 are applied in the width direction. It is preferably a size that can be formed.
  • the support base material 20 and the release film 40 are joined to the patch sheet 10 conveyed by the transfer conveyor 18 by the ultrasonic vibration device 9.
  • the support base material 20 and the release film 40 are joined in a shape parallel to the contour portion which is the outer peripheral edge of the patch 1 on the patch sheet 10, and are performed around the contour portion.
  • the support base material 20 and the release film 40 may be joined at the position of the contour portion of the patch 1 on the patch sheet 10 over the entire circumference along the contour portion, or the patch on the patch sheet 10. It may be performed around the contour portion at a position separated inward from the contour portion of 1.
  • the support base material 20 and the release film 40 are joined at the position of the contour portion of the patch 1 on the patch sheet 10 along the contour portion.
  • the patch sheet 10 has a plurality of patches 1 continuous in at least one direction (longitudinal direction) and a plurality of patches 1 in the other direction (width direction) orthogonal to the one direction. From the above, the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the other direction (width direction) and the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the one direction (longitudinal direction). The support base material 20 and the release film 40 are joined to the cutting line L2).
  • the support base material 20 and the release film 40 are joined at the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is lined up in the other direction (width direction).
  • the first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B are arranged on the release film 40 side with respect to the patch sheet 10.
  • the first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B are provided with horns 90 and 91 having contact surfaces 90A and 91A with respect to the patch sheet 10 as ultrasonic transmitting parts, respectively, and an oscillator (shown in the figure).
  • an AC voltage is supplied to the piezoelectric vibrator, ultrasonic vibration is generated and the horns 90 and 91 vibrate at high speed.
  • the first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B approach and separate from the patch sheet 10 by the first moving mechanism (not shown) and the second moving mechanism (not shown), respectively.
  • the contact surfaces 90A and 91A of the horns 90 and 91 come into contact with the patch sheet 10 along the cutting lines L1 and L2.
  • ultrasonic vibration acts on the release film 40 of the patch sheet 10 along the cutting lines L1 and L2 by the horns 90 and 91.
  • the release film 40 and the support base material 20 are welded along the cutting lines L1 and L2, and the release film 40 and the support base material 20 are formed at the contour portion which is the outer peripheral edge of the patch 1. Are joined.
  • the patch sheet 10 is sandwiched between the ultrasonic vibrating device 9 and the cutting blade of the cutting device 8, and the patch sheet 10 is sandwiched by the ultrasonic vibrating device 9.
  • the cutting step of cutting the patch sheet 10 with the cutting blade of the cutting device 8 is performed at the same time while applying ultrasonic vibration to the surface.
  • the cutting device 8 corresponds to the first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B of the ultrasonic vibration device 9, respectively, and the patch sheet 10 is arranged in the other direction (width direction) of the patch 1.
  • the first cutting device 8A that cuts at the boundary portion (cutting line L1) and the second cutting device 8B that cuts the patch sheet 10 at the boundary portion (cutting line L2) of the patches 1 that are lined up in the one direction (longitudinal direction). And have.
  • the first cutting device 8A and the second cutting device 8B are arranged on the support base material 20 side with respect to the patch sheet 10.
  • the first cutting device 8A includes a plurality of cutting blades 80 provided at intervals in the width direction of the patch sheet 10, and a rotation drive mechanism (rotating) for making each cutting blade 80 rotatable. (Not shown).
  • the first cutting device 8A is arranged so that each cutting blade 80 faces each horn 90 of the first ultrasonic vibration device 9A with the patch sheet 10 interposed therebetween.
  • Each cutting blade 80 is, for example, a rotary blade having a disk shape and a cutting edge having a substantially V-shaped cross section, and is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting blade is conveyed.
  • each cutting blade 80 is arranged so that the cutting edge abuts along a plurality of parallel cutting lines L1 extending in the longitudinal direction with respect to the patch sheet 10 wider than the patch 1.
  • each cutting blade 80 sandwiches the patch sheet 10 with each horn 90, so that a wide patch can be attached at each cutting line L1. Cut the agent sheet 10.
  • the patch sheet 10 is divided into the same width as the patch 1.
  • the cutting blade 80 does not necessarily have to be a rotary blade as in the present embodiment.
  • the second cutting device 8B includes a cutting blade 81 whose cutting edge has a substantially V-shaped cross section.
  • the second cutting device 8B is arranged such that the cutting blade 81 faces the horn 91 of the second ultrasonic vibrating device 9B with the patch sheet 10 interposed therebetween.
  • the cutting blade 81 is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting edge is conveyed, and the cutting edge is arranged along the width direction of the patch 10.
  • the cutting blade 81 sandwiches the patch sheet 10 with the horn 91 when the second ultrasonic vibration device 9B approaches the patch sheet 10, so that the patch is longer than the patch 1.
  • the patch sheet 10 is sequentially cut at each cutting line L2 at a predetermined interval along the longitudinal direction with respect to the sheet 10. As a result, the patch sheet 10 is divided into a plurality of patch 1.
  • the patch sheet 10 is sandwiched between the horns 90 and 91 and the cutting blades 80 and 81, and each of the horns 90 and 91 cuts the patch sheet 10 while applying ultrasonic vibration to the patch sheet 10.
  • the water-based gel 3 is released to the cutting blades 80 at the time of cutting. Since it does not adhere to, 81, the patch sheet 10 can be cut with high accuracy.
  • the release film 40 of the patch sheet 10 is cut at the cutting lines L1 and L2.
  • the release film 40 and the support base material 20 are welded together to bond the release film 40 and the support base material 20. Therefore, with respect to the patch 1 after cutting, as shown in FIGS. 5 and 6, the outer peripheral edges of the support base material 2 and the release film 4 can be bonded over the entire circumference, and the aqueous gel 3 can be bonded to the support base material 2 and the support base material 2. It can be sealed inside the release film 4.
  • the support base material 20 is made of polyethylene terephthalate fiber and a non-woven fabric made of polypropylene fiber
  • the release film 40 is made of polypropylene film. Is preferable.
  • each of the cutting blades 80 and 81 when the cutting edge of each of the cutting blades 80 and 81 has a small cutting edge angle ⁇ and a sharp tip, it becomes easier to cut the patch sheet 10, while supporting the manufactured patch 1.
  • the bond between the base material 2 and the release film 4 becomes weak.
  • the cutting edge angle ⁇ is appropriately set in order to achieve both the ease of cutting the patch sheet 10 and the bonding strength of the supporting base material 2 and the release film 4.
  • the cutting edges of the cutting blades 80 and 81 do not necessarily have to be sharpened, and may have a flat portion having a predetermined width at the tip as shown in FIG. 4 (B).
  • the patch 1 individually cut from the patch sheet 10 by the cutting step is transported to the next step by the transport conveyor 19 arranged at the lower position in the vertical direction.
  • the patch 1 is manually or mechanically packed in a non-breathable storage bag, and in the subsequent step, a treatment for solidifying the aqueous gel 3 is performed, so that the patch 1 is formed. Is manufactured.
  • a patch sheet 10 in which a plurality of patches 1 are continuous in at least one direction is placed in parallel with a contour portion which is an outer peripheral edge of the patch 1 and is supported by the support base material 20.
  • the release film 40 all around and cutting at the contour portion, in the patch 1 after cutting, as shown in FIGS. 5 and 6, the support base material 2 and the release film 4 A joint portion 5 is formed along the outer peripheral edge, and the aqueous gel 3 is enclosed in the support base material 2 and the release film 4. Therefore, even if the aqueous gel 3 has a high water content and high fluidity, it is possible to prevent the aqueous gel 3 from leaking from the outer peripheral edge of the patch 1 during line transportation of the patch 1 after cutting. ..
  • the joint portion 5 of the support base material 2 and the release film 4 in the patch 1 after cutting may have a slightly large band shape as shown in FIG. 6 or a small band shape as shown in FIG. 7. Although it may be streaky, the smaller the width W of the joint portion 5, the wider the aqueous gel 3 can be laminated closer to the outer peripheral edge of the supporting base material 2, which is preferable.
  • By laminating the aqueous gel 3 on almost the entire area of the supporting base material 2 with a sufficient thickness it is possible to increase the range of the skin on which the desired cooling force can be exerted by the patch 1.
  • the outer peripheral edge of the supporting base material 2 adheres well to the skin due to the adhesiveness of the aqueous gel 3, and the outer peripheral edge of the supporting base material 2 is less likely to roll up, so that the patch 1 can be easily peeled off from the skin. It can be suppressed.
  • the width W of the joint portion 5 is preferably 2.0 mm or less, more preferably 1.0 mm or less, and further preferably 0.5 mm or less. Further, the lower limit of the width W of the joint portion 5 is preferably 0.05 mm or more, more preferably 0.1 mm or more, and 0. It is more preferably 2 mm or more.
  • the water-based gel 3 is pressed by pressing the front surface and / or the back surface of the patch 1 during transportation or storage of the patch 1, the water-based gel 3 is extruded to the outside of the patch 1. It is possible to prevent it from sticking out from the peripheral edge. This makes it possible to prevent the aqueous gel 3 from adhering to the user's hand when the user uses the patch 1.
  • the patch 1 since the patch 1 is stored in a packaging box (not shown) in a state of being stacked in a plurality of layers during transportation, storage, etc., the patch 1 bears the weight of the other plurality of patches 1.
  • the aqueous gel 3 Upon receiving, the aqueous gel 3 is compressed. Conventionally, since the aqueous gel 3 may be pressed and protrude from the outer peripheral edge of the patch 1, a partition is set in the packaging box, and the weight of the patch 1 is received by the partition to receive the weight of the patch 1, and the aqueous gel 3 is used. Was prevented from being squeezed.
  • the manufactured patch 1 is attached even if the aqueous gel 3 is pressed by the weight of a plurality of other patches 1 in the packaging box. Since it does not protrude from the outer peripheral edge of the agent 1, a partition is not required, and the cost can be reduced accordingly.
  • the support base material 20 and the release film 40 are joined and cut at the same time with respect to the patch sheet 10, so that the production efficiency of the patch 1 is reduced by shortening the process time. Can be improved.
  • the horns 90 and 91 of the ultrasonic vibration devices 9A and 9B are brought into contact with the patch sheet 10, and the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are brought into contact with each other. Since the patch sheet 10 is cut on the contact surfaces 90A and 91A by pressing against the horns 90 and 91, the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are pressed to cut the patch sheet 10. It is possible to eliminate the need for a backing plate for the purpose.
  • the water-based gel 3 does not leak from the outer peripheral edge of the patch 1 even if the water-based gel 3 has a high water content and high fluidity. Therefore, the processing time of the treatment step for solidifying the aqueous gel 3 after the cutting step of the patch sheet 10 described above can be shortened or this treatment step can be eliminated. The manufacturing efficiency can be improved.
  • the joining step and the cutting step are performed at the same time, but the cutting may be performed after the supporting base material 20 and the release film 40 are bonded to the patch sheet 10.
  • the patch sheet 10 has a contour portion that becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions of the cutting lines L1 and L2 shown in FIG.
  • the supporting base material 20 and the release film 40 are joined together.
  • the patch sheet 10 becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions on both sides of the cutting lines L1 and L2 shown in FIG.
  • the supporting base material 20 and the release film 40 may be joined at a position inside from the contour portion, and may be cut into individual patches 1 at the respective cutting lines L1 and L2. At this time, as shown in FIG.
  • the patch 1 after cutting is joined by the joining portion 5 at a position P2 separated inward from the position P1 of the outer peripheral edge of each of the supporting base material 2 and the release film 4. Since the position P2 of the joint portion 5 is separated inward from the position P1 of the outer peripheral edge of the support base material 2 and the release film 4, the outer peripheral edge of the release film 4 is not bonded to the support base material 2 by the joint portion 5.
  • the release film 4 can be easily peeled off from the support base material 2.
  • the distance of the position P2 from the position P1 is not particularly limited, but is preferably 1.0 mm or more and 2.0 mm or less.
  • the release film 4 can be easily peeled off from the support base material 2, and the aqueous gel 3 can be laminated over a wide range closer to the outer peripheral edge of the support base material 2.
  • the release film 4 and the support base material 2 do not have to be attached to each other between the position P2 and the position P1.
  • the joint portion is formed by the adhesiveness of the aqueous gel 3 slightly existing on the support base material 2. It may be attached with a force weaker than 5.
  • the support base material 20 and the release film 40 are joined to the patch sheet 10 by ultrasonic welding with ultrasonic vibration devices 9A and 9B, but the support base material 20 and the release film 40 are welded.
  • the method is not particularly limited as long as at least one of the support base material 20 and the release film 40 is joined by melting, and the support base material 2 and the release film 4 are overlapped with each other.
  • Various known methods such as heat welding (heat sealing) that pressurize both while applying heat in the state can be used. For example, by hot-pressing the patch sheet 10 along the respective cutting lines L1 and L2 using a pair of upper and lower thermal pressure rolls or a press mold (not shown), the support base material 20 and the release film 40 are heat-welded (not shown). It can be joined by heat sealing).
  • the patch sheet 10 has a size in which a plurality of patches 1 are continuous in both the longitudinal direction and the width direction, but a plurality of patches 1 are continuous only in the longitudinal direction. It may be of a size.
  • the patch 1 has a rectangular shape in a plan view, but may have another shape such as a square shape or a substantially elliptical shape.
  • the patch 1 has a three-layer structure of the support base material 2, the aqueous gel 3, and the release film 4, but may have other layers.
  • the coating device 6 for applying the aqueous gel 3 to one surface of the long support base material 20, the bonding device 7 for bonding the long support base material 20 and the release film 40, and the patch sheet 10 are cut.
  • the cutting devices 8A and 8B are not necessarily limited to the devices of the above-described embodiment, and other known devices can be used.
  • the patch 1 is a sheet-shaped coolant and the adhesive layer is an aqueous gel 3, but the patch is particularly applicable as long as it is used by sticking it on human skin.
  • the adhesive layer is not limited, and may be an adhesive other than the aqueous gel 3 as long as it has an adhesive property that allows the supporting base material 2 to be attached to human skin.
  • Patch sheet 1 Patch 2 Supporting base material 3 Aqueous gel (adhesive layer) 4 Release film 8 Cutting device 9 Ultrasonic vibration device 10 Patch sheet 11 Base material supply roll 15 Film supply roll 20 Long support base material 40 Long release film 90,91 Horn

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Abstract

The present invention provides a method for producing an adhesive patch, said method being capable of preventing protrusion of an adhesive layer. A method for producing an adhesive patch according to the present invention comprises: a bonding step wherein an adhesive patch sheet (10), in which a plurality of adhesive patches (1) are successively arranged at least in one direction, each of said adhesive patches (1) comprising a supporting base material (2), an aqueous gel (3) (an adhesive layer) that is superposed on one surface of the supporting base material (2), and a release film (4) that covers the aqueous gel (3), is subjected to bonding of a supporting base material (20) and a release film (40) along the entirety of the outline part that is the outer periphery of each adhesive patch (1); and a cutting step wherein the adhesive patch sheet (10) is cut in the outline part.

Description

貼付剤の製造方法Manufacturing method of patch
　本発明は、人の皮膚に貼り付けて使用される貼付剤の製造方法に関する。 The present invention relates to a method for producing a patch to be used by sticking to human skin.
　この種の貼付剤として、例えば、発熱時、頭痛時、歯痛時、炎症時等の患部の冷却、顔等の火照りの冷却、またはスポーツ後の筋肉のクールダウン等のために、パップ剤や冷却剤等が従来から使用されている。図９に示すように、従来の貼付剤１００は、不織布等の支持基材１０１上に粘着層１０２として水性ゲルが積層されるとともに粘着層１０２を剥離フィルム１０３で覆った構造のものが一般に知られている。 As this kind of patch, for example, for cooling the affected area during fever, headache, toothache, inflammation, etc., cooling the burning of the face, etc., or cooling down the muscles after sports, etc. Agents and the like have been used conventionally. As shown in FIG. 9, it is generally known that the conventional patch 100 has a structure in which an aqueous gel is laminated as an adhesive layer 102 on a supporting base material 101 such as a non-woven fabric and the adhesive layer 102 is covered with a release film 103. Has been done.
　この従来の貼付剤１００は、例えば特許文献１に示されるように、長尺の支持基材上に粘着層を塗布した後にその表面に長尺の剥離フィルムを重ね合わせた帯状の貼付剤シートを、切断刃により所定のサイズに切断することで製造される。特許文献１では、貼付剤シートを切断刃により個々の所定サイズの貼付剤に切断する前に、貼付剤シートの切断位置をプレス加工することにより当該切断位置の粘着層を押し出して排除する筋付けを行っている。これにより、切断後の貼付剤の端面（切断面）に粘着層が露出することを防止している。 As shown in Patent Document 1, for example, the conventional patch 100 is a strip-shaped patch sheet in which an adhesive layer is applied on a long support base material and then a long release film is laminated on the surface thereof. , Manufactured by cutting to a predetermined size with a cutting blade. In Patent Document 1, before cutting the patch sheet into individual predetermined size patches with a cutting blade, the cutting position of the patch sheet is pressed to extrude and eliminate the adhesive layer at the cut position. It is carried out. This prevents the adhesive layer from being exposed on the end surface (cut surface) of the patch after cutting.
特許第４２４５３４３号公報Japanese Patent No. 4245343
　しかしながら、特許文献１に記載の方法で製造された貼付剤１００は、その外周縁において支持基材１０１と剥離フィルム１０３とが接合されているわけではない。そのため、貼付剤１の表面及び／又は裏面が押圧される等して荷重がかかると、粘着層１０２が押し出されて貼付剤１の外周縁からはみ出すおそれがあり、これは粘着層１０２の厚みが大きい場合や粘着層１０２の流動性が高い場合に顕著な問題となる。これを解消するために粘着層１０２の固化を促進する工程が必要になり、製造コストの増加の原因となっている。 However, in the patch 100 manufactured by the method described in Patent Document 1, the support base material 101 and the release film 103 are not bonded to each other at the outer peripheral edge thereof. Therefore, when a load is applied such that the front surface and / or the back surface of the patch 1 is pressed, the adhesive layer 102 may be pushed out and protrude from the outer peripheral edge of the patch 1, which means that the thickness of the adhesive layer 102 is increased. This becomes a remarkable problem when the size is large or when the adhesive layer 102 has high fluidity. In order to solve this problem, a step of promoting solidification of the adhesive layer 102 is required, which causes an increase in manufacturing cost.
　本発明は、上記課題を解決するためになされたものであり、粘着層のはみ出しを防止することができる貼付剤の製造方法を提供することを目的とする。 The present invention has been made to solve the above problems, and an object of the present invention is to provide a method for producing a patch that can prevent the adhesive layer from sticking out.
　本発明は、支持基材と、前記支持基材の一方面に積層された粘着層と、前記粘着層を覆う剥離フィルムと、を備えた貼付剤の製造方法に関する。本発明の貼付剤の製造方法は、支持基材、前記支持基材の一方面に積層された粘着層、及び前記粘着層を覆う剥離フィルムを備えた貼付剤が少なくとも一方向に複数連続する貼付剤シートについて、前記貼付剤の外周縁となる輪郭部分で前記支持基材及び前記剥離フィルムを接合する接合工程と、前記輪郭部分において前記貼付剤シートを切断する切断工程と、を含むことを特徴とする。 The present invention relates to a method for producing a patch comprising a supporting base material, an adhesive layer laminated on one surface of the supporting base material, and a release film covering the adhesive layer. In the method for producing a patch of the present invention, a plurality of patches having a support base material, an adhesive layer laminated on one surface of the support base material, and a release film covering the pressure-sensitive adhesive layer are continuously attached in at least one direction. The agent sheet is characterized by including a joining step of joining the supporting base material and the release film at a contour portion serving as an outer peripheral edge of the patch, and a cutting step of cutting the patch sheet at the contour portion. And.
　本発明の貼付剤の製造方法においては、前記接合工程では、前記貼付剤シートの前記輪郭部分で前記支持基材及び前記剥離フィルムを接合するように、構成することができる。あるいは、本発明の貼付剤の製造方法においては、前記接合工程では、前記貼付剤シートの前記輪郭部分から内側に離れた位置で前記支持基材及び前記剥離フィルムを接合するように、構成することができる。 In the method for producing a patch of the present invention, in the bonding step, the support base material and the release film can be bonded at the contour portion of the patch sheet. Alternatively, in the method for producing a patch of the present invention, in the bonding step, the support base material and the release film are bonded at a position separated inward from the contour portion of the patch sheet. Can be done.
　また、本発明の貼付剤の製造方法においては、前記接合工程では、超音波振動装置により前記剥離フィルム側から超音波振動を作用させることにより前記支持基材及び前記剥離フィルムを接合するように、構成することができる。該貼付剤の製造方法においては、前記接合工程では、前記超音波振動装置及び切断刃の間で前記貼付剤シートを挟持して、前記超音波振動装置により超音波振動を作用させながら前記切断刃により前記輪郭部分において前記貼付剤シートを切断することで、前記切断工程を同時に行うように、構成することができ、さらに、前記超音波振動装置は、前記貼付剤シートと当接するホーンを備え、前記接合工程では、前記ホーンの前記貼付剤シートに対する当接面上で前記切断刃が前記輪郭部分において前記貼付剤シートを切断するように、構成することができる。 Further, in the method for producing a patch of the present invention, in the bonding step, the supporting base material and the release film are bonded by applying ultrasonic vibration from the release film side by an ultrasonic vibration device. Can be configured. In the method for producing the patch, in the joining step, the patch sheet is sandwiched between the ultrasonic vibrating device and the cutting blade, and the cutting blade is subjected to ultrasonic vibration by the ultrasonic vibrating device. By cutting the patch sheet at the contour portion, the cutting step can be performed at the same time, and the ultrasonic vibration device further includes a horn that comes into contact with the patch sheet. In the joining step, the cutting blade can be configured to cut the patch sheet at the contour portion on the contact surface of the horn with respect to the patch sheet.
　また、本発明の貼付剤の製造方法においては、前記接合工程では、前記支持基材及び前記剥離フィルムを熱溶着することにより接合するように、構成することができる。 Further, in the method for producing a patch of the present invention, in the bonding step, the supporting base material and the release film can be configured to be bonded by heat welding.
　また、本発明の貼付剤の製造方法においては、前記支持基材が不織布であるように、構成することができる。該貼付剤の製造方法においては、前記不織布が熱溶着性繊維を含み、前記剥離フィルムが熱溶着性フィルムであるように、構成することができ、さらに、前記熱溶着性繊維がポリプロピレン繊維であり、前記熱溶着性フィルムがポリプロピレンフィルムであるように、構成することができる。 Further, in the method for producing a patch of the present invention, the supporting base material can be configured to be a non-woven fabric. In the method for producing the patch, the non-woven fabric can be configured to contain heat-weldable fibers and the release film is a heat-weldable film, and further, the heat-weldable fibers are polypropylene fibers. , The heat-weldable film can be configured to be a polypropylene film.
　また、本発明の貼付剤においては、前記粘着層が水性ゲルであり、前記水性ゲルの水分含有量が６０重量％以上９５重量％以下であるように、構成することができる。 Further, in the patch of the present invention, the adhesive layer can be configured to be an aqueous gel, and the water content of the aqueous gel is 60% by weight or more and 95% by weight or less.
　また、本発明の貼付剤の製造方法においては、前記接合工程の前に、基材供給ロールの外周面に幾重に巻き付けられた長尺の支持基材を巻き出して搬送する基材搬送工程と、搬送される前記長尺の支持基材の一方面に前記粘着層を塗布する塗布工程と、フィルム供給ロールの外周面に幾重に巻き付けられた長尺の剥離フィルムを巻き出して前記長尺の支持基材の前記粘着層上に重ね合わせることにより前記貼付剤シートとするシート形成工程と、を含むように、構成することができる。 Further, in the method for producing a patch of the present invention, before the joining step, there is a base material transporting step of unwinding and transporting a long supporting base material wound on the outer peripheral surface of the base material supply roll in multiple layers. The coating process of applying the adhesive layer to one surface of the long supporting base material to be conveyed, and the long release film wound several times around the outer peripheral surface of the film supply roll are unwound to form the long release film. It can be configured to include a sheet forming step of forming the patch sheet by superimposing it on the adhesive layer of the support base material.
　本発明の貼付剤の製造方法によれば、貼付剤シートの切断前又は切断時に、貼付剤シートに対して、貼付剤の外周縁となる輪郭部分に並行する形で剥離フィルム及び支持基材の接合を一周にわたって行う。そのため、切断後の貼付剤においては、支持基材及び剥離フィルムがそれぞれの外周縁に沿って接合されているので、輸送時等に貼付剤の表面及び／又は裏面が押圧される等して荷重がかかっても、粘着層が押し出されて貼付剤の外周縁からはみ出ることを防止することができる。また、貼付剤の製造時に粘着層の固化を促進するための工程を短縮あるいは省略することができる。 According to the method for producing a patch of the present invention, the release film and the supporting base material are formed in parallel with the contour portion which is the outer peripheral edge of the patch with respect to the patch sheet before or when the patch sheet is cut. Joining is done around the circumference. Therefore, in the patch after cutting, the supporting base material and the release film are joined along the outer peripheral edges of the respective patches, so that the front surface and / or the back surface of the patch is pressed during transportation or the like to load the patch. Even if it is applied, it is possible to prevent the adhesive layer from being extruded and protruding from the outer peripheral edge of the patch. Further, the step for promoting the solidification of the adhesive layer during the production of the patch can be shortened or omitted.
本実施形態の製造方法の概略構成図である。It is a schematic block diagram of the manufacturing method of this embodiment. 貼付剤シートの一部分の平面図である。It is a top view of a part of a patch sheet. 第１超音波振動装置及び第１切断装置による接合工程及び切断工程の概略構成図である。It is a schematic block diagram of the joining process and the cutting process by the 1st ultrasonic vibration apparatus and the 1st cutting apparatus. 切断刃の刃先の概略構成図である。It is a schematic block diagram of the cutting edge of a cutting blade. 本実施形態の製造方法により製造された貼付剤の平面図である。It is a top view of the patch manufactured by the manufacturing method of this embodiment. 図５のＡ－Ａ断面を拡大して示す縦断面図である。It is a vertical cross-sectional view which shows the AA cross section of FIG. 5 enlarged. 本実施形態の製造方法により製造された変形例の貼付剤において、図５のＡ－Ａ線に沿う縦断面の概略構成を示す断面図である。It is sectional drawing which shows the schematic structure of the vertical cross section along the line AA of FIG. 5 in the patch of the modified example manufactured by the manufacturing method of this embodiment. 本実施形態の製造方法により製造された変形例の貼付剤において、図５のＡ－Ａ線に沿う縦断面の概略構成を示す断面図である。It is sectional drawing which shows the schematic structure of the vertical cross section along the line AA of FIG. 5 in the patch of the modified example manufactured by the manufacturing method of this embodiment. 従来例の貼付剤の縦断面図である。It is a vertical cross-sectional view of the pasting agent of the conventional example.
　以下、本発明の実施形態について添付図面を参照して説明する。図１は、本発明の一実施形態に係る貼付剤の製造方法の概略構成を示している。なお、本実施形態の貼付剤の製造方法により製造される貼付剤は、人の皮膚に貼り付けて使用されるものであり、例えば発熱時、頭痛時、歯痛時、炎症時等の患部の冷却、顔等の火照りの冷却、またはスポーツ後の筋肉のクールダウン等のために用いられるシート状の冷却剤を例示することができる。図５及び図６に示すように、貼付剤１は、支持基材２と、粘着層としての水性ゲル３と、剥離フィルム４とを少なくとも備え、これらが積層された層構造を有している。貼付剤１は、使用時には、剥離フィルム４を支持基材２から剥がし、露出した水性ゲル３を皮膚の冷却対象部位に直接あてることで、水性ゲル３が有する粘着性により使用者の皮膚に貼り付けられる。これにより、水性ゲル３に含まれた水分が時間の経過に伴い蒸発し、その際に奪われる気化熱で水性ゲル３の温度が低下するため、水性ゲル３に接する皮膚が冷却される。 Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings. FIG. 1 shows a schematic configuration of a method for producing a patch according to an embodiment of the present invention. The patch produced by the method for producing the patch of the present embodiment is used by being attached to human skin, and for example, cooling the affected area during fever, headache, toothache, inflammation, etc. A sheet-shaped cooling agent used for cooling the heat of a face or the like, or cooling down muscles after sports can be exemplified. As shown in FIGS. 5 and 6, the patch 1 includes at least a support base material 2, an aqueous gel 3 as an adhesive layer, and a release film 4, and has a layered structure in which these are laminated. .. At the time of use, the patch 1 is attached to the user's skin due to the adhesiveness of the aqueous gel 3 by peeling the release film 4 from the supporting base material 2 and directly applying the exposed aqueous gel 3 to the part to be cooled on the skin. Attached. As a result, the water contained in the aqueous gel 3 evaporates with the passage of time, and the temperature of the aqueous gel 3 is lowered by the heat of vaporization taken at that time, so that the skin in contact with the aqueous gel 3 is cooled.
　以下、図１～図３に基づいて、本実施形態の貼付剤の製造方法の各工程について順に説明する。なお、各図において貼付剤１や貼付剤シート１０の各構成部材の厚みは、理解が容易なように誇張して描いてあることに留意されたい。 Hereinafter, each step of the method for producing the patch according to the present embodiment will be described in order based on FIGS. 1 to 3. It should be noted that the thickness of each component of the patch 1 and the patch sheet 10 is exaggerated in each drawing for easy understanding.
　本実施形態の貼付剤の製造方法は、長尺の支持基材２０を搬送する基材搬送工程と、搬送される長尺の支持基材２０の一方面に粘着層としての水性ゲル３を塗布する塗布工程と、長尺の剥離フィルム４０を長尺の支持基材２０の水性ゲル３上に重ね合わせることにより貼付剤シート１０とするシート形成工程と、貼付剤シート１０の所定部分で支持基材２０及び剥離フィルム４０を接合する接合工程と、貼付剤シート１０を個々の貼付剤１に切断する切断工程とを含んでいる。各工程には、各工程における処理を実施するための処理装置が設けられている。 In the method for producing a patch of the present embodiment, a base material transporting step of transporting a long support base material 20 and an aqueous gel 3 as an adhesive layer are applied to one surface of the long support base material 20 to be transported. A coating step of forming a patch sheet 10 by superimposing a long release film 40 on an aqueous gel 3 of a long support base material 20, and a support group at a predetermined portion of the patch sheet 10. It includes a joining step of joining the material 20 and the release film 40, and a cutting step of cutting the patch sheet 10 into individual patches 1. Each process is provided with a processing device for carrying out the processing in each process.
　まず、基材搬送工程では、基材供給ロール１１の外周面に幾重に巻き付けられた長尺の支持基材２０を基材供給ロール１１から巻き出してその長手方向を搬送方向として支持ロール１２まで搬送する。基材供給ロール１１は、ロール状に巻き回された長尺の支持基材２０を支持している。 First, in the base material transfer step, a long support base material 20 wound around the outer peripheral surface of the base material supply roll 11 in multiple layers is unwound from the base material supply roll 11 and up to the support roll 12 with the longitudinal direction thereof as the transfer direction. Transport. The base material supply roll 11 supports a long support base material 20 wound in a roll shape.
　長尺の支持基材２０は、水性ゲル３をその一方面上で支持する。支持基材２０は、一定の形に成形されたものではなく、柔軟に変形可能なシート状である。支持基材２０は、例えば透湿性や通気性を有していて、水性ゲル３を担持できるものであれば、そのシート構造は特に限定されるものではなく、種々の織布、不織布及びフィルム等で構成することができるが、その中でも不織布で構成することが好ましい。支持基材２０を織布や不織布で構成する場合には、その素材として、綿、麻、羊毛等の天然繊維；レーヨン、アセテート等のセルロース系繊維；ナイロン、ビニロン、スチロール、ポリプロピレン、ポリエチレン、ポリエチレンテレフタレート、アクリル等の合成樹脂繊維；及び各種繊維を混ぜた繊維（混綿品や混繊品）等を例示することができる。また、支持基材２をフィルムに構成する場合には、その素材として、ポリスチレン（スチロール）、ポリプロピレン、ポリエチレンテレフタレート、ポリエチレン等を例示することができる。 The long support base material 20 supports the aqueous gel 3 on one surface thereof. The support base material 20 is not formed into a fixed shape, but is in the form of a sheet that can be flexibly deformed. The sheet structure of the support base material 20 is not particularly limited as long as it has moisture permeability and breathability and can support the water-based gel 3, and various woven fabrics, non-woven fabrics, films and the like are used. However, among them, it is preferable to use a non-woven fabric. When the support base material 20 is composed of a woven fabric or a non-woven fabric, the materials thereof are natural fibers such as cotton, linen and wool; cellulose fibers such as rayon and acetate; nylon, vinylon, styrene, polypropylene, polyethylene and polyethylene. Examples thereof include synthetic resin fibers such as terephthalate and acrylic; and fibers (blended cotton products and mixed fiber products) in which various fibers are mixed. Further, when the support base material 2 is formed of a film, polystyrene (styrene), polypropylene, polyethylene terephthalate, polyethylene and the like can be exemplified as the material thereof.
　長尺の支持基材２０は、上述した種々の素材を用いて形成できるが、その中でも、例えばポリプロピレン繊維等の熱溶着性を有する合成繊維（熱溶着性繊維）を含んだ不織布で構成することが好ましい。支持基材２０に熱溶着性繊維を含ませることで、後述する接合工程において支持基材２０及び剥離フィルム４０に対して熱や超音波振動を与えると、支持基材２０中の熱溶着性繊維が溶融し剥離フィルム４０（例えばポリプロピレンフィルム等の熱溶着性フィルムからなるもの）と一体化することにより、支持基材２０と剥離フィルム４０とを溶着により接合することができる。 The long support base material 20 can be formed by using various materials described above, and among them, it is made of a non-woven fabric containing synthetic fibers (heat-welding fibers) having heat-welding properties such as polypropylene fibers. Is preferable. By including the heat-weldable fiber in the support base material 20, when heat or ultrasonic vibration is applied to the support base material 20 and the release film 40 in the joining step described later, the heat-weldable fiber in the support base material 20 is applied. Is melted and integrated with the release film 40 (for example, one made of a heat-weldable film such as a polypropylene film), so that the support base material 20 and the release film 40 can be joined by welding.
　長尺の支持基材２０は、１層に限らず、２層又は３層以上の積層体で構成されていてもよい。長尺の支持基材２０が１層で構成される場合には、支持基材２０は、例えばポリエチレンテレフタレート繊維と熱溶着性繊維との混繊品であることが好ましい。支持基材２０が２層以上の積層体で構成される場合には、支持基材２０は、剥離フィルム４と接する側に熱溶着性繊維からなる層が面する積層体からなることが好ましい。 The long support base material 20 is not limited to one layer, and may be composed of a laminate of two layers or three or more layers. When the long support base material 20 is composed of one layer, the support base material 20 is preferably a mixed fiber product of, for example, polyethylene terephthalate fibers and heat-weldable fibers. When the support base material 20 is composed of two or more layers, the support base material 20 is preferably made of a laminate in which a layer made of heat-weldable fibers faces the side in contact with the release film 4.
　長尺の支持基材２０の厚みは、特に限定されるものではないが、製造される貼付剤１の使用感、貼付部位への馴染み易さ等の観点から、０．１ｍｍ以上３．０ｍｍ以下であることが好ましく、０．５ｍｍ以上２．０ｍｍ以下であることがより好ましい。 The thickness of the long support base material 20 is not particularly limited, but is 0.1 mm or more and 3.0 mm or less from the viewpoint of the usability of the manufactured patch 1 and the ease of fitting to the patch site. It is preferably 0.5 mm or more and 2.0 mm or less.
　長尺の支持基材２０の幅（長手方向と直交する方向の長さ）は、特に限定されるものではないが、個々の貼付剤１を幅方向に複数形成できる大きさであることが好ましい。 The width of the long support base material 20 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but is preferably a size capable of forming a plurality of individual patches 1 in the width direction. ..
　次に、塗布工程では、搬送される長尺の支持基材２０の一方面に塗布装置６により粘着層として水性ゲル３を塗布して積層させる。塗布装置６は、水性ゲル３を貯留するタンク１３と、タンク１３から水性ゲル３を取り出して長尺の支持基材２０に塗布する塗布ロール１４と、長尺の支持基材２０を塗布ロール１４との間で挟持する支持ロール１２とで構成されている。塗布ロール１４は、外周面の一部分がタンク１３内の水性ゲル３に浸漬しており、矢印の方向に回転することによって、タンク１３内の水性ゲル３を外周面に付着させることにより水性ゲル３をタンク１３から取り出す。そして、塗布ロール１４は、外周面に付着させた水性ゲル３を、支持ロール１２に支持された長尺の支持基材２０に一方面に塗布する。 Next, in the coating step, the aqueous gel 3 is applied as an adhesive layer on one surface of the long supporting base material 20 to be conveyed by the coating device 6 and laminated. The coating device 6 includes a tank 13 for storing the aqueous gel 3, a coating roll 14 for taking out the aqueous gel 3 from the tank 13 and applying it to the long support base material 20, and a coating roll 14 for applying the long support base material 20. It is composed of a support roll 12 sandwiched between the two. A part of the outer peripheral surface of the coating roll 14 is immersed in the water-based gel 3 in the tank 13, and the water-based gel 3 in the tank 13 is adhered to the outer peripheral surface by rotating in the direction of the arrow. Is taken out from the tank 13. Then, the coating roll 14 applies the aqueous gel 3 adhered to the outer peripheral surface to one surface of the long supporting base material 20 supported by the supporting roll 12.
　水性ゲル３は、粘着性に加えて、抱水性、放湿性、自己保形性等を有する。「抱水性」とは、内部に水を安定的に含む性質を意味するが、より好ましくはさらに圧縮しても含有水分を滲出しない性質を意味する。また「自己保形性」とは、流動性や崩壊性を顕著には生じず形状を保持している性質を意味する。 Aqueous gel 3 has water-holding property, moisture-releasing property, self-retaining property, etc. in addition to adhesiveness. The "water-holding property" means a property of stably containing water inside, but more preferably a property of not exuding the contained water even when further compressed. Further, "self-retaining property" means a property of retaining the shape without significantly causing fluidity or disintegration.
　水を含んでかかる性質を奏し得る成分としては、一般にゲル化剤として用いられる天然高分子多糖類を例示することができる。具体的には、カラギーナン、アルギン酸、アルギン酸プロピレングリコールエステル、タラガム、ローカストビーンガム、グルコマンナン、キサンタンガム、ジェランガム、ペクチン、プルラン、グァーガム、サイリウムシードガム、アルギン酸ナトリウム、マンナン、ゼラチン、寒天等の天然ガム類を例示することができる。これらは単独若しくは２種以上の組み合わせて用いることができる。好ましくはグルコマンナン、ローカストビーンガムを例示することができる。  As a component that contains water and can exhibit such properties, a natural high molecular weight polysaccharide generally used as a gelling agent can be exemplified. Specifically, natural gums such as carrageenan, alginic acid, propylene glycol alginate, tara gum, locust bean gum, glucomannan, xanthan gum, gellan gum, pectin, purulan, guar gum, psyllium seed gum, sodium alginate, mannan, gelatin, and agar. Can be exemplified. These can be used alone or in combination of two or more. Glucomannan and locust bean gum can be preferably exemplified.
　ゲル化剤としては、上述した天然高分子多糖類以外に、ポリアクリル酸、ポリメタアクリル酸、ポリアクリル酸の塩、ポリメタアクリル酸の塩等を例示することができる。これらは単独若しくは２種以上の組み合わせて用いることができる。 Examples of the gelling agent include polyacrylic acid, polymethacrylic acid, salts of polyacrylic acid, salts of polymethacrylic acid, and the like, in addition to the above-mentioned natural high molecular weight polysaccharides. These can be used alone or in combination of two or more.
　水性ゲル３は、その他の成分として、多価アルコール、界面活性剤、防腐剤、保存剤、安定剤、香料、着色料、ｐＨ調整剤、リモネン、カンフル、ハッカ油又はｌ－メントール等の清涼化剤、保湿剤、刺激剤、除菌剤、抗菌剤、粘着付与剤、保型剤、増粘剤等、公知の添加剤を含有していてもよい。 Aqueous gel 3 refreshes polyhydric alcohol, surfactant, preservative, preservative, stabilizer, fragrance, colorant, pH adjuster, limonene, camphor, peppermint oil, l-menthol and the like as other components. It may contain known additives such as agents, moisturizers, stimulants, disinfectants, antibacterial agents, pressure-imparting agents, shape-retaining agents, and thickeners.
　水性ゲル３は、所望の冷却力を持続的に発揮するために、十分な量の水分を含んでいることが好ましく、水性ゲル３の水分含有量としては、水性ゲル３を構成する組成物中、６０重量％以上であることが好ましく、７０重量％以上であることがより好ましい。また、水性ゲル３の水分含有量の上限は、自己保形性の観点から、９５重量％以下であることが好ましく、９０重量％以下であることがより好ましい。 The water-based gel 3 preferably contains a sufficient amount of water in order to continuously exert a desired cooling power, and the water content of the water-based gel 3 is determined in the composition constituting the water-based gel 3. , 60% by weight or more, more preferably 70% by weight or more. Further, the upper limit of the water content of the aqueous gel 3 is preferably 95% by weight or less, more preferably 90% by weight or less, from the viewpoint of self-retaining property.
　水性ゲル３の厚みは、特に限定されるものではないが、冷却力、皮膚に貼り付けた時の感触、皮膚に対する貼り付け状態の維持等の観点から、適度に大きいことが好ましい。例えば、図６に示す製造後の貼付剤１において、支持基材２の中央における水性ゲル３の厚みＤＣが０．１ｍｍ以上２０ｍｍ以下であることが好ましく、１．０ｍｍ以上１０ｍｍ以下であることがより好ましい。また、水性ゲル３の厚みは、支持基材２の全域において均一あるいはほぼ均一であることが好ましく、中央における水性ゲル３の厚みＤＣと外周縁付近における水性ゲル３の厚みＤＥとでほとんど差がないこと（ＤＥ≒ＤＣ）が好ましい。なお、水性ゲル３の厚みは、支持基材２の全域において必ずしも均一あるいはほぼ均一である必要はなく、図示は省略するが、支持基材２の中央の方が外周縁付近よりも水性ゲル３の厚みが大きくてもよいし（ＤＣ＞ＤＥ）、支持基材２の中央よりも外周縁付近の方が水性ゲル３の厚みが大きくてよい（ＤＥ＞ＤＣ）。水性ゲル３の厚みは、支持基材２の外周縁に向かうに連れて徐々に小さくなる又は徐々に大きくなる、あるいは、支持基材２の外周縁に近い部分だけが外周縁に向かうに連れて徐々に小さくなる又は徐々に大きくなっていてもよい。 The thickness of the aqueous gel 3 is not particularly limited, but is preferably moderately large from the viewpoints of cooling power, feel when attached to the skin, maintenance of the attached state to the skin, and the like. For example, the patch 1 after manufacture as shown in FIG. 6, the thickness D C of the aqueous gel 3 at the center of the supporting substrate 2 is preferably 0.1mm or more 20mm or less, and less than 1.0mm 10mm or less Is more preferable. The thickness of the aqueous gel 3 is preferably uniform or substantially uniform over the entire area of the supporting substrate 2, almost the thickness D E of the aqueous gel 3 in the vicinity of the thickness D C and the outer peripheral edge of the aqueous gel 3 in the central it is no difference (D E ≒ D C) is preferred. The thickness of the water-based gel 3 does not necessarily have to be uniform or almost uniform over the entire area of the support base material 2, and although not shown, the center of the support base material 2 is closer to the center of the support base material 2 than the vicinity of the outer peripheral edge. may be large thickness of (D C> D E), towards the vicinity of the outer peripheral edge than the center of the supporting substrate 2 may be larger thickness aqueous gel 3 (D E> D C) . The thickness of the aqueous gel 3 gradually decreases or gradually increases toward the outer peripheral edge of the supporting base material 2, or only the portion close to the outer peripheral edge of the supporting base material 2 becomes toward the outer peripheral edge. It may be gradually reduced or gradually increased.
　水性ゲル３の厚みは、例えば、支持基材２の中央における厚みＤＣに対する支持基材２の接合部５より１．０ｍｍ内側の厚みＤＥの比ＤＥ／ＤＣが０．１以上２．０以下であることが好ましく、０．３以上１．２以下であることがより好ましく、０．５以上１．０以下であることがさらに好ましい。なお、水性ゲル３の厚みは、ＪＩＳ　Ｌ１９１３：２０１０の「６．１　厚さ（ＩＳＯ法）」に記載されている方法を用いて計測することができる。 The thickness of the aqueous gel 3, for example, the ratio D E / D C of the supporting substrate 2 of the joint 5 from 1.0mm inner thickness D E to the thickness D C at the center of the supporting substrate 2 is 0.1 or more 2 It is preferably 0.0 or less, more preferably 0.3 or more and 1.2 or less, and further preferably 0.5 or more and 1.0 or less. The thickness of the aqueous gel 3 can be measured by using the method described in "6.1 Thickness (ISO method)" of JIS L1913: 2010.
　次に、図１～図３に戻って、シート形成工程では、フィルム供給ロール１５の外周面に幾重に巻き付けられた長尺の剥離フィルム４０を巻き出してその長手方向を搬送方向として貼合ロール１６まで搬送する。フィルム供給ロール１５は、ロール状に巻き回された長尺の剥離フィルム４０を支持している。そして、搬送される長尺の剥離フィルム４０を、貼合装置７により水性ゲル３が積層された長尺の支持基材２０と貼り合わせて貼付剤シート１０とする。貼合装置７は、支持ロール１２と貼合ロール１６とで構成されていて、長尺の支持基材２０の水性ゲル３上に長尺の剥離フィルム４０を重ね合わせた状態で両ロール１２，１６の間を通過させることで、長尺の支持基材２０に積層された水性ゲル３の厚みを所定の厚みに調整したうえで、貼付剤シート１０を形成する。形成された貼付剤シート１０は、搬送ロール１７、さらにベルトコンベヤ等の搬送コンベヤ１８により次工程の切断装置８まで搬送される。 Next, returning to FIGS. 1 to 3, in the sheet forming step, the long release film 40 wound in multiple layers on the outer peripheral surface of the film supply roll 15 is unwound and the bonding roll is bonded with its longitudinal direction as the transport direction. Transport up to 16. The film supply roll 15 supports a long release film 40 wound in a roll shape. Then, the long release film 40 to be conveyed is bonded to the long support base material 20 on which the water-based gel 3 is laminated by the bonding device 7 to form a patch sheet 10. The bonding device 7 is composed of a support roll 12 and a bonding roll 16, and both rolls 12 are in a state where the long release film 40 is superposed on the aqueous gel 3 of the long support base material 20. The patch sheet 10 is formed after adjusting the thickness of the aqueous gel 3 laminated on the long support base material 20 to a predetermined thickness by passing between 16. The formed patch sheet 10 is conveyed to the cutting device 8 in the next step by a transfer roll 17 and a transfer conveyor 18 such as a belt conveyor.
　長尺の剥離フィルム４０は、水性ゲル３を被覆できるものであれば、その素材は特に限定されるものではなく、ポリプロピレン、ポリエチレン、ポリエステル、ナイロン、塩化ビニル、ポリエチレンテレフタレート等の合成樹脂を例示することができる。その中でも、剥離フィルム４０は、例えばポリオレフィン系樹脂フィルム（例えばポリプロピレンフィルムやポリエチレンフィルム等）等の熱溶着性を有するフィルム（熱溶着性フィルム）を用いることが好ましい。なお、長尺の支持基材２０及び剥離フィルム４０は、熱溶着や超音波溶着をし易くする観点から、同じ素材を用いて形成することが好ましく、特にポリプロピレンを用いて形成することが好ましい。 The material of the long release film 40 is not particularly limited as long as it can coat the aqueous gel 3, and examples thereof include synthetic resins such as polypropylene, polyethylene, polyester, nylon, vinyl chloride, and polyethylene terephthalate. be able to. Among them, as the release film 40, it is preferable to use a film having heat welding properties (heat welding film) such as a polyolefin resin film (for example, polypropylene film, polyethylene film, etc.). The long supporting base material 20 and the release film 40 are preferably formed using the same material, and particularly preferably polypropylene, from the viewpoint of facilitating heat welding and ultrasonic welding.
　長尺の剥離フィルム４０の厚みは、特に限定されるものではなく、例えば０．０２ｍｍ以上０．３ｍｍ以下とすることができ、より好ましくは０．０３ｍｍ以上０．２ｍｍ以下とすることができる。 The thickness of the long release film 40 is not particularly limited, and can be, for example, 0.02 mm or more and 0.3 mm or less, and more preferably 0.03 mm or more and 0.2 mm or less.
　長尺の剥離フィルム４０の幅（長手方向と直交する方向の長さ）は、特に限定されるものではないが、長尺の支持基材２０と同じく、個々の貼付剤１を幅方向に複数形成できる大きさであることが好ましい。 The width of the long release film 40 (the length in the direction orthogonal to the longitudinal direction) is not particularly limited, but like the long support base material 20, a plurality of individual patches 1 are applied in the width direction. It is preferably a size that can be formed.
　次に、接合工程では、搬送コンベヤ１８により搬送される貼付剤シート１０に対して、支持基材２０及び剥離フィルム４０を超音波振動装置９によって接合する。支持基材２０及び剥離フィルム４０の接合は、貼付剤シート１０において貼付剤１の外周縁となる輪郭部分に並行した形で行われ、該輪郭部分に沿って一周にわたり行われる。なお、支持基材２０及び剥離フィルム４０の接合は、貼付剤シート１０における貼付剤１の輪郭部分の位置で該輪郭部分に沿って一周にわたり行われてもよいし、貼付剤シート１０における貼付剤１の輪郭部分から内側に離れた位置で該輪郭部分に沿って一周にわたり行われてもよい。 Next, in the joining step, the support base material 20 and the release film 40 are joined to the patch sheet 10 conveyed by the transfer conveyor 18 by the ultrasonic vibration device 9. The support base material 20 and the release film 40 are joined in a shape parallel to the contour portion which is the outer peripheral edge of the patch 1 on the patch sheet 10, and are performed around the contour portion. The support base material 20 and the release film 40 may be joined at the position of the contour portion of the patch 1 on the patch sheet 10 over the entire circumference along the contour portion, or the patch on the patch sheet 10. It may be performed around the contour portion at a position separated inward from the contour portion of 1.
　本実施形態では、支持基材２０及び剥離フィルム４０の接合は、貼付剤シート１０における貼付剤１の輪郭部分の位置で該輪郭部分に沿って一周にわたり行われる。貼付剤シート１０は、図２に示すように、貼付剤１が少なくとも一方向（長手方向）に複数連続するとともに前記一方向と直交する他方向（幅方向）にも複数連続したものであることから、貼付剤シート１０を前記他方向（幅方向）に並ぶ貼付剤１の境界部分（切断ラインＬ１）と、貼付剤シート１０を前記一方向（長手方向）に並ぶ貼付剤１の境界部分（切断ラインＬ２）とで支持基材２０及び剥離フィルム４０を接合する。 In the present embodiment, the support base material 20 and the release film 40 are joined at the position of the contour portion of the patch 1 on the patch sheet 10 along the contour portion. As shown in FIG. 2, the patch sheet 10 has a plurality of patches 1 continuous in at least one direction (longitudinal direction) and a plurality of patches 1 in the other direction (width direction) orthogonal to the one direction. From the above, the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the other direction (width direction) and the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is arranged in the one direction (longitudinal direction). The support base material 20 and the release film 40 are joined to the cutting line L2).
　そのため、本実施形態の超音波振動装置９は、貼付剤シート１０を前記他方向（幅方向）に並ぶ貼付剤１の境界部分（切断ラインＬ１）で支持基材２０及び剥離フィルム４０を接合する第１超音波振動装置９Ａと、貼付剤シート１０を前記一方向（長手方向）に並ぶ貼付剤１の境界部分（切断ラインＬ２）で支持基材２０及び剥離フィルム４０を接合する第２超音波振動装置９Ｂとを備えている。第１超音波振動装置９Ａ及び第２超音波振動装置９Ｂは、貼付剤シート１０に対して剥離フィルム４０側に配置されている。 Therefore, in the ultrasonic vibration device 9 of the present embodiment, the support base material 20 and the release film 40 are joined at the boundary portion (cutting line L1) of the patch 1 in which the patch sheet 10 is lined up in the other direction (width direction). The second ultrasonic wave that joins the support base material 20 and the release film 40 at the boundary portion (cutting line L2) between the first ultrasonic vibration device 9A and the patch 1 in which the patch sheet 10 is arranged in one direction (longitudinal direction). It is equipped with a vibrating device 9B. The first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B are arranged on the release film 40 side with respect to the patch sheet 10.
　第１超音波振動装置９Ａ及び第２超音波振動装置９Ｂは、それぞれ、超音波発信部として貼付剤シート１０に対する当接面９０Ａ，９１Ａを有するホーン９０，９１を備えており、発振器（図示せず）から圧電振動子に交流電圧が供給されることで超音波振動が発生してホーン９０，９１が高速で振動する。第１超音波振動装置９Ａ及び第２超音波振動装置９Ｂは、それぞれ第１移動機構（図示せず）及び第２移動機構（図示せず）により、貼付剤シート１０に対して接近及び離反する方向に移動可能であり、貼付剤シート１０に対して接近した際に各ホーン９０，９１の当接面９０Ａ，９１Ａが各切断ラインＬ１，Ｌ２に沿って貼付剤シート１０に当接する。このとき、各ホーン９０，９１によって、貼付剤シート１０の剥離フィルム４０には各切断ラインＬ１，Ｌ２に沿って超音波振動が作用する。これにより、貼付剤シート１０は、各切断ラインＬ１，Ｌ２に沿って剥離フィルム４０と支持基材２０とが溶着し、貼付剤１の外周縁となる輪郭部分では剥離フィルム４０及び支持基材２０が接合される。 The first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B are provided with horns 90 and 91 having contact surfaces 90A and 91A with respect to the patch sheet 10 as ultrasonic transmitting parts, respectively, and an oscillator (shown in the figure). When an AC voltage is supplied to the piezoelectric vibrator, ultrasonic vibration is generated and the horns 90 and 91 vibrate at high speed. The first ultrasonic vibrating device 9A and the second ultrasonic vibrating device 9B approach and separate from the patch sheet 10 by the first moving mechanism (not shown) and the second moving mechanism (not shown), respectively. It is movable in the direction, and when it approaches the patch sheet 10, the contact surfaces 90A and 91A of the horns 90 and 91 come into contact with the patch sheet 10 along the cutting lines L1 and L2. At this time, ultrasonic vibration acts on the release film 40 of the patch sheet 10 along the cutting lines L1 and L2 by the horns 90 and 91. As a result, in the patch sheet 10, the release film 40 and the support base material 20 are welded along the cutting lines L1 and L2, and the release film 40 and the support base material 20 are formed at the contour portion which is the outer peripheral edge of the patch 1. Are joined.
　図１に戻って、本実施形態では、この接合工程において、貼付剤シート１０を超音波振動装置９と切断装置８の切断刃との間で挟持し、超音波振動装置９により貼付剤シート１０に超音波振動を作用させながら切断装置８の切断刃により貼付剤シート１０を切断する切断工程を同時に行っている。 Returning to FIG. 1, in the present embodiment, in this joining step, the patch sheet 10 is sandwiched between the ultrasonic vibrating device 9 and the cutting blade of the cutting device 8, and the patch sheet 10 is sandwiched by the ultrasonic vibrating device 9. The cutting step of cutting the patch sheet 10 with the cutting blade of the cutting device 8 is performed at the same time while applying ultrasonic vibration to the surface.
　切断装置８は、超音波振動装置９の第１超音波振動装置９Ａ及び第２超音波振動装置９Ｂにそれぞれ対応して、貼付剤シート１０を前記他方向（幅方向）に並ぶ貼付剤１の境界部分（切断ラインＬ１）で切断する第１切断装置８Ａと、貼付剤シート１０を前記一方向（長手方向）に並ぶ貼付剤１の境界部分（切断ラインＬ２）で切断する第２切断装置８Ｂとを備えている。第１切断装置８Ａ及び第２切断装置８Ｂは、貼付剤シート１０に対して支持基材２０側に配置されている。 The cutting device 8 corresponds to the first ultrasonic vibration device 9A and the second ultrasonic vibration device 9B of the ultrasonic vibration device 9, respectively, and the patch sheet 10 is arranged in the other direction (width direction) of the patch 1. The first cutting device 8A that cuts at the boundary portion (cutting line L1) and the second cutting device 8B that cuts the patch sheet 10 at the boundary portion (cutting line L2) of the patches 1 that are lined up in the one direction (longitudinal direction). And have. The first cutting device 8A and the second cutting device 8B are arranged on the support base material 20 side with respect to the patch sheet 10.
　第１切断装置８Ａは、例えば図３に示すように、貼付剤シート１０の幅方向に間隔をあけて設けられた複数の切断刃８０と、各切断刃８０を回転可能とする回転駆動機構（図示せず）とを備えている。第１切断装置８Ａは、各切断刃８０が貼付剤シート１０を挟んで第１超音波振動装置９Ａの各ホーン９０と対向するように配置されている。各切断刃８０は、例えば円盤状でかつ刃先が断面視略Ｖ字状を呈する回転刃であり、刃先が搬送される貼付剤シート１０に当接又は近接するように配置されている。また、各切断刃８０は、貼付剤１よりも幅広の貼付剤シート１０に対して長手方向に延びる互いに平行な複数の切断ラインＬ１に沿って刃先が当たるように配置されている。各切断刃８０は、第１超音波振動装置９Ａが貼付剤シート１０に対して接近した際に各ホーン９０との間で貼付剤シート１０を挟持することで、各切断ラインＬ１で幅広の貼付剤シート１０を切断する。これにより、貼付剤シート１０を貼付剤１と同幅に分断する。なお、各切断刃８０は、必ずしも本実施形態のような回転刃である必要はない。 As shown in FIG. 3, for example, the first cutting device 8A includes a plurality of cutting blades 80 provided at intervals in the width direction of the patch sheet 10, and a rotation drive mechanism (rotating) for making each cutting blade 80 rotatable. (Not shown). The first cutting device 8A is arranged so that each cutting blade 80 faces each horn 90 of the first ultrasonic vibration device 9A with the patch sheet 10 interposed therebetween. Each cutting blade 80 is, for example, a rotary blade having a disk shape and a cutting edge having a substantially V-shaped cross section, and is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting blade is conveyed. Further, each cutting blade 80 is arranged so that the cutting edge abuts along a plurality of parallel cutting lines L1 extending in the longitudinal direction with respect to the patch sheet 10 wider than the patch 1. When the first ultrasonic vibrating device 9A approaches the patch sheet 10, each cutting blade 80 sandwiches the patch sheet 10 with each horn 90, so that a wide patch can be attached at each cutting line L1. Cut the agent sheet 10. As a result, the patch sheet 10 is divided into the same width as the patch 1. The cutting blade 80 does not necessarily have to be a rotary blade as in the present embodiment.
　第２切断装置８Ｂは、刃先が断面視略Ｖ字状を呈する切断刃８１を備えている。第２切断装置８Ｂは、切断刃８１が貼付剤シート１０を挟んで第２超音波振動装置９Ｂのホーン９１と対向するように配置されている。切断刃８１は、刃先が搬送される貼付剤シート１０に当接又は近接するように配置されるとともに、刃先が貼付剤１０の幅方向に沿うように配置されている。切断刃８１は、第２超音波振動装置９Ｂが貼付剤シート１０に対して接近した際にホーン９１との間で貼付剤シート１０を挟持することで、貼付剤１よりも長尺の貼付剤シート１０に対して長手方向に沿って所定間隔のあいた各切断ラインＬ２で貼付剤シート１０を順次切断する。これにより、貼付剤シート１０を複数の貼付剤１に分断する。 The second cutting device 8B includes a cutting blade 81 whose cutting edge has a substantially V-shaped cross section. The second cutting device 8B is arranged such that the cutting blade 81 faces the horn 91 of the second ultrasonic vibrating device 9B with the patch sheet 10 interposed therebetween. The cutting blade 81 is arranged so that the cutting edge is in contact with or close to the patch sheet 10 to which the cutting edge is conveyed, and the cutting edge is arranged along the width direction of the patch 10. The cutting blade 81 sandwiches the patch sheet 10 with the horn 91 when the second ultrasonic vibration device 9B approaches the patch sheet 10, so that the patch is longer than the patch 1. The patch sheet 10 is sequentially cut at each cutting line L2 at a predetermined interval along the longitudinal direction with respect to the sheet 10. As a result, the patch sheet 10 is divided into a plurality of patch 1.
　以上のように、各ホーン９０，９１と各切断刃８０，８１との間で貼付剤シート１０を挟持し、各ホーン９０，９１で貼付剤シート１０に超音波振動を作用させながら、各切断刃８０，８１を各ホーン９０，９１の当接面９０Ａ，９１Ａに押し当てて貼付剤シート１０を各切断ラインＬ１，Ｌ２に沿って切断することで、切断時に水性ゲル３が各切断刃８０，８１に付着等することがないため、貼付剤シート１０を高精度に切断することができる。 As described above, the patch sheet 10 is sandwiched between the horns 90 and 91 and the cutting blades 80 and 81, and each of the horns 90 and 91 cuts the patch sheet 10 while applying ultrasonic vibration to the patch sheet 10. By pressing the blades 80 and 81 against the contact surfaces 90A and 91A of the horns 90 and 91 to cut the patch sheet 10 along the cutting lines L1 and L2, the water-based gel 3 is released to the cutting blades 80 at the time of cutting. Since it does not adhere to, 81, the patch sheet 10 can be cut with high accuracy.
　また、貼付剤シート１０の剥離フィルム４０に各切断ラインＬ１，Ｌ２に沿って各ホーン９０，９１により超音波振動を作用させることで、貼付剤シート１０の各切断ラインＬ１，Ｌ２においては、切断と同時に、剥離フィルム４０と支持基材２０とが溶着して剥離フィルム４０及び支持基材２０が接合される。そのため、切断後の貼付剤１について、図５及び図６に示すように、支持基材２及び剥離フィルム４の外周縁を全周にわたって接合することができ、水性ゲル３を支持基材２及び剥離フィルム４の内部に封入することができる。なお、支持基材２０及び剥離フィルム４０の接合及び切断を良好に行うためには、支持基材２０がポリエチレンテレフタレート繊維及びポリプロピレン繊維を素材とする不織布からなり、剥離フィルム４０がポリプロピレンフィルムからなることが好ましい。 Further, by applying ultrasonic vibration to the release film 40 of the patch sheet 10 along the cutting lines L1 and L2 by the horns 90 and 91, the release film 40 of the patch sheet 10 is cut at the cutting lines L1 and L2. At the same time, the release film 40 and the support base material 20 are welded together to bond the release film 40 and the support base material 20. Therefore, with respect to the patch 1 after cutting, as shown in FIGS. 5 and 6, the outer peripheral edges of the support base material 2 and the release film 4 can be bonded over the entire circumference, and the aqueous gel 3 can be bonded to the support base material 2 and the support base material 2. It can be sealed inside the release film 4. In order to satisfactorily bond and cut the support base material 20 and the release film 40, the support base material 20 is made of polyethylene terephthalate fiber and a non-woven fabric made of polypropylene fiber, and the release film 40 is made of polypropylene film. Is preferable.
　各切断刃８０，８１の刃先は、図４（Ａ）に示すように、刃先角度θが小さく先が鋭いと、貼付剤シート１０を切断し易くなる一方で、製造される貼付剤１の支持基材２及び剥離フィルム４の接合が弱くなる。また、刃先角度θが大きく先が鈍いと、製造される貼付剤１の支持基材２及び剥離フィルム４の接合が強くなる一方で、貼付剤シート１０を切断し難くなる。そのため、貼付剤シート１０の切断し易さと支持基材２及び剥離フィルム４の接合強度との両立のために、刃先角度θは適宜設定される。なお、各切断刃８０，８１の刃先は、必ずしも先が尖っている必要はなく、図４（Ｂ）に示すように、先に所定幅の平坦な部分を有していてもよい。 As shown in FIG. 4A, when the cutting edge of each of the cutting blades 80 and 81 has a small cutting edge angle θ and a sharp tip, it becomes easier to cut the patch sheet 10, while supporting the manufactured patch 1. The bond between the base material 2 and the release film 4 becomes weak. Further, if the cutting edge angle θ is large and the tip is blunt, the bonding between the supporting base material 2 and the release film 4 of the manufactured patch 1 becomes strong, but it becomes difficult to cut the patch sheet 10. Therefore, the cutting edge angle θ is appropriately set in order to achieve both the ease of cutting the patch sheet 10 and the bonding strength of the supporting base material 2 and the release film 4. The cutting edges of the cutting blades 80 and 81 do not necessarily have to be sharpened, and may have a flat portion having a predetermined width at the tip as shown in FIG. 4 (B).
　図１に戻って、最後に、切断工程により貼付剤シート１０から個々に切断された貼付剤１は、鉛直方向の下方位置に配置された搬送コンベア１９により次工程に搬送される。次工程では、貼付剤１が非通気性の収納袋内に手作業又は機械を用いて袋詰めされ、そして、その後の工程で水性ゲル３を固めるための処理が行われることで、貼付剤１が製造される。 Returning to FIG. 1, finally, the patch 1 individually cut from the patch sheet 10 by the cutting step is transported to the next step by the transport conveyor 19 arranged at the lower position in the vertical direction. In the next step, the patch 1 is manually or mechanically packed in a non-breathable storage bag, and in the subsequent step, a treatment for solidifying the aqueous gel 3 is performed, so that the patch 1 is formed. Is manufactured.
　上述した本実施形態の貼付剤の製造方法によると、少なくとも一方向に貼付剤１が複数連続する貼付剤シート１０を、貼付剤１の外周縁となる輪郭部分に並行する形で支持基材２０及び剥離フィルム４０の接合を一周にわたり行い、かつ、該輪郭部分で切断することで、切断後の貼付剤１においては、図５及び図６に示すように、支持基材２及び剥離フィルム４の外周縁に沿って接合部５が形成され、水性ゲル３が支持基材２及び剥離フィルム４内に封入される。よって、水分含有量が多くて流動性の高い水性ゲル３であっても、切断後の貼付剤１のライン搬送時に水性ゲル３が貼付剤１の外周縁から漏れ出すことを防止することができる。 According to the method for producing a patch of the present embodiment described above, a patch sheet 10 in which a plurality of patches 1 are continuous in at least one direction is placed in parallel with a contour portion which is an outer peripheral edge of the patch 1 and is supported by the support base material 20. And, by joining the release film 40 all around and cutting at the contour portion, in the patch 1 after cutting, as shown in FIGS. 5 and 6, the support base material 2 and the release film 4 A joint portion 5 is formed along the outer peripheral edge, and the aqueous gel 3 is enclosed in the support base material 2 and the release film 4. Therefore, even if the aqueous gel 3 has a high water content and high fluidity, it is possible to prevent the aqueous gel 3 from leaking from the outer peripheral edge of the patch 1 during line transportation of the patch 1 after cutting. ..
　切断後の貼付剤１における支持基材２及び剥離フィルム４の接合部５は、図６に示すような幅Ｗの多少大きな帯状であってもよいし、図７に示すような幅Ｗの小さい筋状であってもよいが、接合部５の幅Ｗは小さければ小さいほど、水性ゲル３を支持基材２の外周縁のより近くまで広範囲に積層することができるので好ましい。水性ゲル３が支持基材２のほぼ全域に十分な厚みで積層されていることで、貼付剤１により所望の冷却力を及ぼすことができる皮膚の範囲を増大させることができる。そのうえ、支持基材２の外周縁が水性ゲル３の粘着性により皮膚に良好にくっついて、支持基材２の外周縁が捲れ上がり難くなることから、貼付剤１が皮膚から容易に剥がれるのを抑制することができる。 The joint portion 5 of the support base material 2 and the release film 4 in the patch 1 after cutting may have a slightly large band shape as shown in FIG. 6 or a small band shape as shown in FIG. 7. Although it may be streaky, the smaller the width W of the joint portion 5, the wider the aqueous gel 3 can be laminated closer to the outer peripheral edge of the supporting base material 2, which is preferable. By laminating the aqueous gel 3 on almost the entire area of the supporting base material 2 with a sufficient thickness, it is possible to increase the range of the skin on which the desired cooling force can be exerted by the patch 1. In addition, the outer peripheral edge of the supporting base material 2 adheres well to the skin due to the adhesiveness of the aqueous gel 3, and the outer peripheral edge of the supporting base material 2 is less likely to roll up, so that the patch 1 can be easily peeled off from the skin. It can be suppressed.
　接合部５の幅Ｗは、上述した観点から、２．０ｍｍ以下であることが好ましく、１．０ｍｍ以下であることがより好ましく、０．５ｍｍ以下であることがさらに好ましい。また、接合部５の幅Ｗの下限は、支持基材２及び剥離フィルム４の接合強度の観点から、０．０５ｍｍ以上であることが好ましく、０．１ｍｍ以上であることがより好ましく、０．２ｍｍ以上であることがさらに好ましい。 From the above viewpoint, the width W of the joint portion 5 is preferably 2.0 mm or less, more preferably 1.0 mm or less, and further preferably 0.5 mm or less. Further, the lower limit of the width W of the joint portion 5 is preferably 0.05 mm or more, more preferably 0.1 mm or more, and 0. It is more preferably 2 mm or more.
　さらに、貼付剤１の輸送時や保管時等に貼付剤１の表面及び／又は裏面が押圧される等して水性ゲル３が圧迫されても、水性ゲル３が押し出されて貼付剤１の外周縁からはみ出すことを防止することができる。これにより、使用者が貼付剤１を使用する際に、使用者の手に水性ゲル３が付着すること等を防止することができる。 Further, even if the water-based gel 3 is pressed by pressing the front surface and / or the back surface of the patch 1 during transportation or storage of the patch 1, the water-based gel 3 is extruded to the outside of the patch 1. It is possible to prevent it from sticking out from the peripheral edge. This makes it possible to prevent the aqueous gel 3 from adhering to the user's hand when the user uses the patch 1.
　そのうえ、貼付剤１は、輸送時や保管時等においては包装箱（図示せず）内に複数重ねられた状態で収納されるため、貼付剤１は、他の複数の貼付剤１の重みを受けることで、水性ゲル３が圧迫される。従来では、水性ゲル３が圧迫されることで貼付剤１の外周縁からはみ出すおそれがあるため、包装箱内に中仕切りをセットし、中仕切りにて貼付剤１の重みを受けて水性ゲル３が圧迫されるのを防止していた。ただし、本実施形態の貼付剤の製造方法によると、製造される貼付剤１は、包装箱内で他の複数の貼付剤１の重みにより水性ゲル３が圧迫されても、水性ゲル３が貼付剤１の外周縁からはみ出ないため、中仕切りが不要となり、その分、コスト低減を図ることができる。 In addition, since the patch 1 is stored in a packaging box (not shown) in a state of being stacked in a plurality of layers during transportation, storage, etc., the patch 1 bears the weight of the other plurality of patches 1. Upon receiving, the aqueous gel 3 is compressed. Conventionally, since the aqueous gel 3 may be pressed and protrude from the outer peripheral edge of the patch 1, a partition is set in the packaging box, and the weight of the patch 1 is received by the partition to receive the weight of the patch 1, and the aqueous gel 3 is used. Was prevented from being squeezed. However, according to the method for producing a patch according to the present embodiment, the manufactured patch 1 is attached even if the aqueous gel 3 is pressed by the weight of a plurality of other patches 1 in the packaging box. Since it does not protrude from the outer peripheral edge of the agent 1, a partition is not required, and the cost can be reduced accordingly.
　また、本実施形態の貼付剤の製造方法によると、貼付剤シート１０に対して支持基材２０及び剥離フィルム４０の接合と切断とを同時に行うので、工程時間の短縮によって貼付剤１の生産効率を向上させることができる。 Further, according to the method for producing a patch of the present embodiment, the support base material 20 and the release film 40 are joined and cut at the same time with respect to the patch sheet 10, so that the production efficiency of the patch 1 is reduced by shortening the process time. Can be improved.
　また、本実施形態の貼付剤の製造方法によると、超音波振動装置９Ａ，９Ｂのホーン９０，９１を貼付剤シート１０に当接させ、切断装置８Ａ，８Ｂの切断刃８０，８１の刃先をホーン９０，９１に押し当てて当接面９０Ａ，９１Ａ上で貼付剤シート１０を切断するので、貼付剤シート１０の切断のために切断装置８Ａ，８Ｂの切断刃８０，８１の刃先を押し当てるための当て板を不要とすることができる。 Further, according to the method for manufacturing a patch of the present embodiment, the horns 90 and 91 of the ultrasonic vibration devices 9A and 9B are brought into contact with the patch sheet 10, and the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are brought into contact with each other. Since the patch sheet 10 is cut on the contact surfaces 90A and 91A by pressing against the horns 90 and 91, the cutting edges of the cutting blades 80 and 81 of the cutting devices 8A and 8B are pressed to cut the patch sheet 10. It is possible to eliminate the need for a backing plate for the purpose.
　また、本実施形態の貼付剤の製造方法によると、水性ゲル３の水分含有量が多くて流動性が高くても、水性ゲル３が貼付剤１の外周縁から漏れ出さない。そのため、上述した貼付剤シート１０の切断工程後の水性ゲル３を固めるための処理工程の処理時間を短縮する又はこの処理工程を不要とすることができるので、工程時間の短縮によって貼付剤１の製造効率を向上させることができる。 Further, according to the method for producing a patch of the present embodiment, the water-based gel 3 does not leak from the outer peripheral edge of the patch 1 even if the water-based gel 3 has a high water content and high fluidity. Therefore, the processing time of the treatment step for solidifying the aqueous gel 3 after the cutting step of the patch sheet 10 described above can be shortened or this treatment step can be eliminated. The manufacturing efficiency can be improved.
　以上、本発明の実施形態について説明したが、本発明は上記実施形態に限定されるものではなく、本発明の趣旨を逸脱しない限りにおいて種々の変更が可能である。 Although the embodiments of the present invention have been described above, the present invention is not limited to the above embodiments, and various modifications can be made without departing from the spirit of the present invention.
　例えば、上記実施形態では、接合工程と切断工程とを同時に行っているが、貼付剤シート１０に対して支持基材２０及び剥離フィルム４０の接合を行った後に切断を行うようにしてもよい。 For example, in the above embodiment, the joining step and the cutting step are performed at the same time, but the cutting may be performed after the supporting base material 20 and the release film 40 are bonded to the patch sheet 10.
　また、上記実施形態において、貼付剤シート１０は、図２に示す各切断ラインＬ１，Ｌ２の位置で支持基材２０及び剥離フィルム４０を溶着することで、貼付剤１の外周縁となる輪郭部分で支持基材２０及び剥離フィルム４０の接合が行われている。しかし、これに限らず、貼付剤シート１０は、図２に示す各切断ラインＬ１，Ｌ２の両側の位置で支持基材２０及び剥離フィルム４０を溶着することで、貼付剤１の外周縁となる輪郭部分から内側の位置で支持基材２０及び剥離フィルム４０の接合を行い、そして、各切断ラインＬ１，Ｌ２で個々の貼付剤１に切断してもよい。このとき、切断後の貼付剤１は、図８に示すように、支持基材２及び剥離フィルム４のそれぞれの外周縁の位置Ｐ１から内側に離れた位置Ｐ２で接合部５により接合される。接合部５の位置Ｐ２が支持基材２及び剥離フィルム４の外周縁の位置Ｐ１から内側に離れていることで、剥離フィルム４の外周縁が支持基材２に接合部５によっては接合されないため、貼付剤１を使用する際に、剥離フィルム４を支持基材２から剥がし易くすることができる。位置Ｐ２の位置Ｐ１からの距離は、特に限定されるものではないが、１．０ｍｍ以上２．０ｍｍ以下であることが好ましい。該距離が上記範囲にあることで、剥離フィルム４を支持基材２から剥がし易くできるうえ、水性ゲル３を支持基材２の外周縁のより近くまで広範囲に積層することができる。なお、位置Ｐ２から位置Ｐ１までの間において、剥離フィルム４と支持基材２とは何らくっついていなくてもよいし、例えば支持基材２上に多少存在する水性ゲル３の粘着性により接合部５よりも弱い力でくっついていてもよい。 Further, in the above embodiment, the patch sheet 10 has a contour portion that becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions of the cutting lines L1 and L2 shown in FIG. The supporting base material 20 and the release film 40 are joined together. However, not limited to this, the patch sheet 10 becomes the outer peripheral edge of the patch 1 by welding the support base material 20 and the release film 40 at the positions on both sides of the cutting lines L1 and L2 shown in FIG. The supporting base material 20 and the release film 40 may be joined at a position inside from the contour portion, and may be cut into individual patches 1 at the respective cutting lines L1 and L2. At this time, as shown in FIG. 8, the patch 1 after cutting is joined by the joining portion 5 at a position P2 separated inward from the position P1 of the outer peripheral edge of each of the supporting base material 2 and the release film 4. Since the position P2 of the joint portion 5 is separated inward from the position P1 of the outer peripheral edge of the support base material 2 and the release film 4, the outer peripheral edge of the release film 4 is not bonded to the support base material 2 by the joint portion 5. When the patch 1 is used, the release film 4 can be easily peeled off from the support base material 2. The distance of the position P2 from the position P1 is not particularly limited, but is preferably 1.0 mm or more and 2.0 mm or less. When the distance is within the above range, the release film 4 can be easily peeled off from the support base material 2, and the aqueous gel 3 can be laminated over a wide range closer to the outer peripheral edge of the support base material 2. The release film 4 and the support base material 2 do not have to be attached to each other between the position P2 and the position P1. For example, the joint portion is formed by the adhesiveness of the aqueous gel 3 slightly existing on the support base material 2. It may be attached with a force weaker than 5.
　また、上記実施形態において、貼付剤シート１０に対する支持基材２０及び剥離フィルム４０の接合を超音波振動装置９Ａ，９Ｂによる超音波溶着により行っているが、支持基材２０及び剥離フィルム４０の溶着の方法は、支持基材２０及び剥離フィルム４０の少なくとも一方が溶融することにより両者が接合されるものであれば特に限定されるものではなく、その他、支持基材２及び剥離フィルム４を重ね合わせた状態で熱を加えながら両者を加圧する熱溶着（ヒートシール）等、公知の種々の方法を用いることができる。例えば上下一対の熱圧ロールやプレス型（図示せず）を用いて貼付剤シート１０を各切断ラインＬ１，Ｌ２に沿って熱プレスすることで、支持基材２０及び剥離フィルム４０を熱溶着（ヒートシール）により接合することができる。 Further, in the above embodiment, the support base material 20 and the release film 40 are joined to the patch sheet 10 by ultrasonic welding with ultrasonic vibration devices 9A and 9B, but the support base material 20 and the release film 40 are welded. The method is not particularly limited as long as at least one of the support base material 20 and the release film 40 is joined by melting, and the support base material 2 and the release film 4 are overlapped with each other. Various known methods such as heat welding (heat sealing) that pressurize both while applying heat in the state can be used. For example, by hot-pressing the patch sheet 10 along the respective cutting lines L1 and L2 using a pair of upper and lower thermal pressure rolls or a press mold (not shown), the support base material 20 and the release film 40 are heat-welded (not shown). It can be joined by heat sealing).
　また、上記実施形態において、貼付剤シート１０は、長手方向及び幅方向のいずれの方向にも貼付剤１が複数連続する大きさのものであるが、長手方向のみに貼付剤１が複数連続する大きさのものであってもよい。 Further, in the above embodiment, the patch sheet 10 has a size in which a plurality of patches 1 are continuous in both the longitudinal direction and the width direction, but a plurality of patches 1 are continuous only in the longitudinal direction. It may be of a size.
　また、上記実施形態において、貼付剤１は、平面視長方形状であるが、正方形状や略楕円形状など、その他の形状とすることができる。 Further, in the above embodiment, the patch 1 has a rectangular shape in a plan view, but may have another shape such as a square shape or a substantially elliptical shape.
　また、上記実施形態において、貼付剤１は、支持基材２、水性ゲル３及び剥離フィルム４の三層構造であるが、その他の層を有していてもよい。 Further, in the above embodiment, the patch 1 has a three-layer structure of the support base material 2, the aqueous gel 3, and the release film 4, but may have other layers.
　また、長尺の支持基材２０の一方面に水性ゲル３を塗布する塗布装置６や、長尺の支持基材２０及び剥離フィルム４０を貼り合わせる貼合装置７、貼付剤シート１０を切断する切断装置８Ａ，８Ｂは、必ずしも上記実施形態の装置に限定されるわけではなく、その他の公知の装置を用いることができる。 Further, the coating device 6 for applying the aqueous gel 3 to one surface of the long support base material 20, the bonding device 7 for bonding the long support base material 20 and the release film 40, and the patch sheet 10 are cut. The cutting devices 8A and 8B are not necessarily limited to the devices of the above-described embodiment, and other known devices can be used.
　また、上記実施形態においては、貼付剤１は、シート状の冷却剤であり、粘着層が水性ゲル３であるが、貼付剤は、人の皮膚に貼り付けて使用されるものであれば特に限定されるものではなく、粘着層は支持基材２を人の皮膚に貼り付けることが可能な粘着性を有していれば、水性ゲル３以外の粘着剤等であってもよい。 Further, in the above embodiment, the patch 1 is a sheet-shaped coolant and the adhesive layer is an aqueous gel 3, but the patch is particularly applicable as long as it is used by sticking it on human skin. The adhesive layer is not limited, and may be an adhesive other than the aqueous gel 3 as long as it has an adhesive property that allows the supporting base material 2 to be attached to human skin.
　１　　貼付剤
　２　　支持基材
　３　　水性ゲル（粘着層）
　４　　剥離フィルム
　８　　切断装置
　９　　超音波振動装置
　１０　貼付剤シート
　１１　基材供給ロール
　１５　フィルム供給ロール
　２０　長尺の支持基材
　４０　長尺の剥離フィルム
　９０，９１　ホーン 1 Patch 2 Supporting base material 3 Aqueous gel (adhesive layer)
4 Release film 8 Cutting device 9 Ultrasonic vibration device 10 Patch sheet 11 Base material supply roll 15 Film supply roll 20 Long support base material 40 Long release film 90,91 Horn

Claims (12)

  1. 　支持基材、前記支持基材の一方面に積層された粘着層、及び前記粘着層を覆う剥離フィルムを備えた貼付剤が少なくとも一方向に複数連続する貼付剤シートについて、前記貼付剤の外周縁となる輪郭部分に並行した形で一周にわたって前記支持基材及び前記剥離フィルムを接合する接合工程と、
    　前記輪郭部分において前記貼付剤シートを切断する切断工程と、を含む、貼付剤の製造方法。     An outer peripheral edge of the patch for a patch sheet in which a plurality of patches having a support base material, an adhesive layer laminated on one surface of the support base material, and a release film covering the adhesive layer are continuous in at least one direction. A joining step of joining the supporting base material and the release film over one circumference in parallel with the contour portion to be formed.
    A method for producing a patch, which comprises a cutting step of cutting the patch sheet at the contour portion.
  2. 　前記接合工程では、前記貼付剤シートの前記輪郭部分で前記支持基材及び前記剥離フィルムを接合する、請求項１に記載の貼付剤の製造方法。 The method for producing a patch according to claim 1, wherein in the joining step, the supporting base material and the release film are joined at the contour portion of the patch sheet.
  3. 　前記接合工程では、前記貼付剤シートの前記輪郭部分から内側に離れた位置で前記支持基材及び前記剥離フィルムを接合する、請求項１に記載の貼付剤の製造方法。 The method for producing a patch according to claim 1, wherein in the joining step, the support base material and the release film are joined at a position separated inward from the contour portion of the patch sheet.
  4. 　前記接合工程では、超音波振動装置により前記剥離フィルム側から超音波振動を作用させることにより前記支持基材及び前記剥離フィルムを接合する、請求項１～３のいずれか一項に記載の貼付剤の製造方法。 The patch according to any one of claims 1 to 3, wherein in the joining step, the supporting base material and the release film are joined by applying ultrasonic vibration from the release film side by an ultrasonic vibration device. Manufacturing method.
  5. 　前記接合工程では、前記超音波振動装置及び切断刃の間で前記貼付剤シートを挟持して、前記超音波振動装置により超音波振動を作用させながら前記切断刃により前記輪郭部分において前記貼付剤シートを切断することで、前記切断工程を同時に行う、請求項４に記載の貼付剤の製造方法。 In the joining step, the patch sheet is sandwiched between the ultrasonic vibrating device and the cutting blade, and the patch sheet is applied to the contour portion by the cutting blade while applying ultrasonic vibration by the ultrasonic vibrating device. The method for producing a patch according to claim 4, wherein the cutting step is performed at the same time by cutting.
  6. 　前記超音波振動装置は、前記貼付剤シートと当接するホーンを備え、
    　前記接合工程では、前記ホーンの前記貼付剤シートに対する当接面上で前記切断刃が前記輪郭部分において前記貼付剤シートを切断する、請求項５に記載の貼付剤の製造方法。     The ultrasonic vibrating device includes a horn that comes into contact with the patch sheet.
    The method for producing a patch according to claim 5, wherein in the joining step, the cutting blade cuts the patch sheet at the contour portion on the contact surface of the horn with respect to the patch sheet.
  7. 　前記接合工程では、前記支持基材及び前記剥離フィルムを熱溶着することにより接合する、請求項１に記載の貼付剤の製造方法。 The method for producing a patch according to claim 1, wherein in the joining step, the supporting base material and the release film are joined by heat welding.
  8. 　前記支持基材が不織布である、請求項１～７のいずれか一項に記載の貼付剤の製造方法。 The method for producing a patch according to any one of claims 1 to 7, wherein the supporting base material is a non-woven fabric.
  9. 　前記不織布が熱溶着性繊維を含み、前記剥離フィルムが熱溶着性フィルムである、請求項８に記載の貼付剤の製造方法。 The method for producing a patch according to claim 8, wherein the non-woven fabric contains heat-weldable fibers and the release film is a heat-weldable film.
  10. 　前記熱溶着性繊維がポリプロピレン繊維であり、
    　前記熱溶着性フィルムがポリプロピレンフィルムである、請求項９に記載の貼付剤。     The heat-weldable fiber is a polypropylene fiber,
    The patch according to claim 9, wherein the heat-weldable film is a polypropylene film.
  11. 　前記粘着層が水性ゲルであり、前記水性ゲルの水分含有量が６０重量％以上９５重量％以下である、請求項１～１０のいずれか一項に記載の貼付剤の製造方法。 The method for producing a patch according to any one of claims 1 to 10, wherein the adhesive layer is an aqueous gel, and the water content of the aqueous gel is 60% by weight or more and 95% by weight or less.
  12. 　前記接合工程の前に、
    　基材供給ロールの外周面に幾重に巻き付けられた長尺の支持基材を巻き出して搬送する基材搬送工程と、
    　搬送される前記長尺の支持基材の一方面に前記粘着層を塗布する塗布工程と、フィルム供給ロールの外周面に幾重に巻き付けられた長尺の剥離フィルムを巻き出して前記長尺の支持基材の前記粘着層上に重ね合わせることにより前記貼付剤シートとするシート形成工程と、を含む、請求項１～１１のいずれか一項に記載の貼付剤の製造方法。     Before the joining step,
    A base material transfer process in which a long support base material wound in multiple layers around the outer peripheral surface of the base material supply roll is unwound and conveyed.
    The coating process of applying the adhesive layer to one surface of the long support base material to be conveyed, and the long release film wound several times around the outer peripheral surface of the film supply roll are unwound to support the long length. The method for producing a patch according to any one of claims 1 to 11, further comprising a sheet forming step of forming the patch sheet by superimposing it on the adhesive layer of the base material.
PCT/JP2019/046845 2019-11-29 2019-11-29 Method for producing adhesive patch WO2021106211A1 (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10235131A (en) * 1997-02-26 1998-09-08 Toppan Printing Co Ltd Sheet-like deoxydizing agent and its cutting method
JP2004201703A (en) * 2002-11-06 2004-07-22 Akatsuki Kinzoku Kogyo:Kk Working line for plaster sheet
JP2005237571A (en) * 2004-02-25 2005-09-08 Terumo Corp Cooling sheet for protecting wound
JP2005304717A (en) * 2004-04-20 2005-11-04 Life Kea Giken Kk Cooling sheet and production method thereof
JP2008119837A (en) * 2006-11-08 2008-05-29 Kiwa Kinzoku:Kk Ultrasonic welding device
JP2010188056A (en) * 2009-02-20 2010-09-02 Medorekkusu:Kk Dressing preparation for applying chemical

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10235131A (en) * 1997-02-26 1998-09-08 Toppan Printing Co Ltd Sheet-like deoxydizing agent and its cutting method
JP2004201703A (en) * 2002-11-06 2004-07-22 Akatsuki Kinzoku Kogyo:Kk Working line for plaster sheet
JP2005237571A (en) * 2004-02-25 2005-09-08 Terumo Corp Cooling sheet for protecting wound
JP2005304717A (en) * 2004-04-20 2005-11-04 Life Kea Giken Kk Cooling sheet and production method thereof
JP2008119837A (en) * 2006-11-08 2008-05-29 Kiwa Kinzoku:Kk Ultrasonic welding device
JP2010188056A (en) * 2009-02-20 2010-09-02 Medorekkusu:Kk Dressing preparation for applying chemical

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