WO2017129775A1 - Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel - Google Patents

Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel Download PDF

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Publication number
WO2017129775A1
WO2017129775A1 PCT/EP2017/051821 EP2017051821W WO2017129775A1 WO 2017129775 A1 WO2017129775 A1 WO 2017129775A1 EP 2017051821 W EP2017051821 W EP 2017051821W WO 2017129775 A1 WO2017129775 A1 WO 2017129775A1
Authority
WO
WIPO (PCT)
Prior art keywords
driver
portions
storage container
retaining
retaining portion
Prior art date
Application number
PCT/EP2017/051821
Other languages
German (de)
English (en)
French (fr)
Inventor
Hardy Schmidt-Ellinger
Original Assignee
Becton Dickinson Rowa Germany Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson Rowa Germany Gmbh filed Critical Becton Dickinson Rowa Germany Gmbh
Priority to JP2018537619A priority Critical patent/JP7010829B2/ja
Priority to AU2017212691A priority patent/AU2017212691A1/en
Priority to BR112018013692-1A priority patent/BR112018013692B1/pt
Priority to CA3012888A priority patent/CA3012888A1/en
Priority to EP17701536.9A priority patent/EP3407854A1/de
Priority to KR1020187021602A priority patent/KR102650781B1/ko
Priority to CN201780008028.1A priority patent/CN108697582A/zh
Publication of WO2017129775A1 publication Critical patent/WO2017129775A1/de
Priority to AU2022203194A priority patent/AU2022203194A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B35/00Supplying, feeding, arranging or orientating articles to be packaged
    • B65B35/02Supply magazines
    • B65B35/04Supply magazines with buffer storage devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B35/00Supplying, feeding, arranging or orientating articles to be packaged
    • B65B35/06Separating single articles from loose masses of articles
    • B65B35/08Separating single articles from loose masses of articles using pocketed conveyors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/10Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles
    • B65B5/101Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity
    • B65B5/103Filling containers or receptacles progressively or in stages by introducing successive articles, or layers of articles by gravity for packaging pills or tablets
    • GPHYSICS
    • G07CHECKING-DEVICES
    • G07FCOIN-FREED OR LIKE APPARATUS
    • G07F17/00Coin-freed apparatus for hiring articles; Coin-freed facilities or services
    • G07F17/0092Coin-freed apparatus for hiring articles; Coin-freed facilities or services for assembling and dispensing of pharmaceutical articles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0076Medicament distribution means

Definitions

  • the present invention relates to a reservoir for medicaments, and more particularly to a reservoir for a drug delivery and delivery station.
  • Modern blister machines as disclosed, for example, in WO 2013/034504 Al, comprise, depending on the expansion stage, several hundred storage and dispensing stations. In each of these, a plurality of drug portions of a particular drug are stored, and on request, individual portions of medication can be dispensed. With the blister machines are stored in the storage and dispensing stations
  • corresponding storage and dispensing stations are driven to deliver one or more isolated portions of medication.
  • a single medication portion is separated with a singulator and transferred via a discharge opening of a guide device of the blister machine.
  • the guide device is a dispensed drug portion, possibly under
  • the separating device For separating the medicament portions, which are stored in a storage container of a supply and dispensing station, the separating device comprises a rotor with a
  • a plurality of channels usually on the outer circumference of the
  • the channels are usually adapted to the respectively to be separated drug portions in terms of their dimension such that in a channel the
  • Medicinal portions only one above the other, but not can be arranged side by side. Regularly, the channels are designed so that only a drug portion finds in this place.
  • a channel is passed through a discharge opening in the housing of the
  • Reservoir moves, and arranged in the channel
  • Medication portion slips or falls into the delivery opening. To avoid having more over the channel
  • Delivered drug portions are also in the area above the discharge opening, a retaining portion of a retaining means is guided at least over the channel, which is aligned with the discharge opening. To prevent further drug portions from entering the channel upon delivery of the drug portions, the retention portion is only slightly above the level from the tops of the channels
  • the retaining portion of the retaining means is at
  • Reservoirs according to the prior art just executed so that, depending on the shape of the drug portions, it may happen that one or more drug portions remain on the retention portion and can not be delivered. If in a reservoir a number of X
  • Medicament portions are deliverable, if it is not ensured that the medicament portions resting on the retention section are removed therefrom.
  • Medicament portions can be delivered.
  • the storage container according to the invention for a supply and dispensing station comprises a housing enclosing a receiving space for medicament portions with a
  • Guide device can be arranged a discharge channel.
  • a separating device is rotatably arranged, which has a plurality of spaced-apart projections and of channels formed between them for receiving medicament portions.
  • the orientation and the width of the protrusions define the dimensioning of the channels between the protrusions. So that a defined number of
  • Each projection has one to the receiving space for
  • Shooting limit level is the receiving space for storing the drug portions, and under the
  • the reservoir further comprises a retaining means having a mounting portion and a retaining portion, wherein the retaining portion is held above the dispensing opening and above the receiving boundary plane and an entry of drug portions in one at the dispensing opening
  • the Retaining portion of the retaining means is always above the projections between which extend the channels
  • the reservoir further comprises a driver for removing drug portions of the retaining portion, said driver above the
  • Recording limit level is movable over the retaining portion. With the help of this movable over the retaining portion driver drug portions, which are on the
  • Retention section lie, away.
  • Reservoir filled drug portions can be dispensed and it is reliably avoided that an unknown number of drug portions on the
  • the driver is by a rotary motion of the
  • Singling device moves in the circular cylindrical portion of the housing above the receiving boundary plane on the retaining portion.
  • the driver moves simultaneously with the channels and projections and, if only one driver is present, each time the singulator is rotated, it is guided or moved once over the retaining section to remove any medicament portions which may be present thereon.
  • the at least one driver is thus part of the separating device, wherein the at least one driver can be designed in one piece with the separating device or is attached to this.
  • the at least one driver has a non-planar surface and / or angled radial end faces, said end faces taper upwards.
  • the driver may be part of the separating device.
  • the at least one driver is not directly connected to the singulator.
  • Rolling body is formed, which is arranged in the recess. This rolling element is due to the rotational movement of the
  • Singling device moves the rolling body on the stationary retaining portion itself. Although the driver in this second embodiment is no longer with the
  • the rolling body may be formed in the shape of a ball, barrel or roller, wherein the recess may be adapted to the exact configuration of the rolling body.
  • the recess can be formed as a coaxial annular gap in which the roller-shaped rolling body is guided.
  • the annular gap can be outward, for example, by the circular cylindrical
  • the inner boundary is defined by a likewise circular-cylindrical section of the
  • the retaining means is flattened at its radial end faces. This flattening also protects the drug portions in the housing, as they may be pressed during a rotational movement against the end faces of the driver. In particular, smaller portions of medication can be damaged. The flattening ensures that the medicament portions are easier to move over the driver.
  • Embodiment of the reservoir show
  • Figures 2a - 2c show various sectional views of the first embodiment
  • Figure 4 shows a view of the singulator of a second embodiment
  • FIGS. 6a - 6c driver according to a fourth and fifth embodiment show.
  • FIGS. 1 a and 1 b show two oblique views of a supply and delivery station with a first embodiment of the storage container 1 according to the invention.
  • FIGS. 1 c and 1 d show top views of the storage container, wherein in FIG. 1 d a separating device 30, which is shown in FIGS.
  • the storage container 1 comprises a housing 10 enclosing a receiving space 2 for medicament portions, which has a circular cylindrical portion 11 in the lower portion.
  • the housing 10 is bounded below by a bottom surface 20 having a
  • Dispensing opening 21 has (see Figure ld).
  • the bottom surface 20 has a further central receptacle 22, which with a Singulating device 30 cooperates.
  • the separating device 30 is arranged in the circular-cylindrical section 11 of the housing 10 and comprises a plurality of channels 33 for receiving a medicament portion.
  • the channels 33 are formed by a plurality of projections 32 each having a surface 32 a.
  • the orientation and width of the protrusions 32 define the dimensioning of the channels 33 between the protrusions. In order to achieve the goal of "isolation”, care must be taken to ensure that a defined number of
  • the projections 32 together with a central part 31, form a rotor which is moved by a drive (not shown).
  • the projections 32 may be formed integrally with the middle part 31, but it is also conceivable that the projections 32 are attached to the outer periphery of the central part 31 and thus the channels are generated on the outer periphery of the central part 31.
  • the circular cylindrical portion 11 of the housing 10 comprises a
  • the retaining means further comprises a retaining portion 42 which has a
  • the storage and dispensing station comprises the storage container 1 according to the invention and usually components which regulate or control the delivery or separation of the medicament portions. These are usually a motor for moving the storage container 1 according to the invention.
  • Separation device 30 and a sensor for checking the delivery of a drug portion may be arranged in the housing 12. Regularly However, the supply and delivery station is two
  • Main components constructed, a reservoir and a (not shown) dispensing device, wherein the
  • Reservoir is detachably mounted on the dispenser. Only for filling or cleaning the reservoir is removed.
  • a handle 13 is provided in the front area.
  • Figure 2a shows a partial side sectional view of the first embodiment of the reservoir of the supply
  • Dispensing station wherein the housing 10 and partially the
  • the separating device 30 comprises a central part 31, on whose outer circumference or lateral surface a plurality of projections 32, each having a surface 32a, are provided by their arrangement and configuration on the circumference of the
  • each channel is designed so that only a drug portion of a channel can be accommodated.
  • the surfaces 32a of the projections 32 define an upper receiving boundary plane (which is indicated graphically in Figure 3c and Figure 4), above which
  • Retaining portion 42 of the retaining means 40 is guided.
  • the retaining portion 42 is via a slot in the
  • Recording limit level is arranged.
  • Singling device 30 is further a driver 35
  • the retaining portion 42 of the retaining means is formed so that it can be guided into and through the slot.
  • FIGS. 2b and 2c show different views of one
  • the projections 32 comprise a surface 32a, the surfaces defining a receiving boundary plane (see FIGS. 3c, 4).
  • the projections 32 define the channels 33, wherein the channel 33 'shown in the figures "front” is aligned on the (not visible here) discharge opening 21.
  • the retaining portion 42 of the retaining means 40 covers the channel 33 ⁇ from above, so that no further
  • Medicament portions can reach in the aligned at the discharge port channel 33 ⁇ .
  • Singling device moves the driver 35 in
  • Singulation device on the retaining portion 42, and possibly on this lying drug portions are removed by the movement of the driver.
  • FIGS. 3a and 3b show detailed views of
  • the driver 35 which is arranged in this embodiment on the outer periphery of the central part 31 of the singulator, is such
  • Figure 3c shows a front view of
  • Shooting limit AE is indicated by two dashed lines.
  • the receiving boundary plane AE is defined by the surfaces 32a of the projections 32.
  • the surfaces 32a of the projections are planar. It is also conceivable in an alternative embodiment that the
  • Surfaces 32a are formed, for example, spherical or conical, and in this case would be the top points of the
  • the retaining section (not shown in FIG. 3c) of the retaining means is always guided over the receiving boundary plane AE, so that a rotation of the separating device is possible.
  • the gap 36 which can be seen in Figure 3c, serves to receive the
  • Singling device 30 further includes a lower axial extension 38 which is integral with receptacle 22 in the bottom surface of
  • FIG. 4 shows a second embodiment of the invention
  • Tappet conically shaped so as to avoid having drug portions on the surface of the tappet
  • Singulation device is the probability that a drug portion lie on the surface of the driver remains low, in the case of a slowly rotating
  • Singling device may be advantageous but the design shown in Figure 4, the top of the driver.
  • the radial end faces of the driver shown in Figure 4 are also not formed perpendicularly, but projecting downwardly obliquely to ensure a smooth moving away of the drug portions of the surface of the retaining portion.
  • only one design variant can be selected, d. H. a conical
  • FIGS. 5a-5d show a third embodiment of the storage container according to the invention, wherein FIGS. 5a and 5b show oblique views and FIGS. 5c and 5d show front views of the separating device together with the retention section 42.
  • FIGS. 5a, 5b and 5d is the sake of clarity of the
  • the driver 35 is not an integral part of this embodiment
  • Separation device 30 itself, but formed as a spherical rolling body, which is arranged in a recess 37 (see in particular figures 5c, 5d) on the receiving boundary plane, wherein in the embodiment shown, the recess is formed as an annular groove.
  • Section 11 of the housing 10 thus an annular gap is formed, in which the driver 35 is arranged, and in which it is moved by movements of the separating device.
  • a driver designed as a rolling element is like the
  • Channels 33 of the singulator to the dimensions of the channels and drug portions and possibly the weight of
  • FIGS 6a, 6b and 6c show two more
  • Embodiments of designed as a rolling body driver wherein the driver once roll-shaped 35 "and once

Landscapes

  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Catching Or Destruction (AREA)
  • Packages (AREA)
PCT/EP2017/051821 2016-01-29 2017-01-27 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel WO2017129775A1 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2018537619A JP7010829B2 (ja) 2016-01-29 2017-01-27 薬品のための貯蔵送達ステーション用貯蔵容器
AU2017212691A AU2017212691A1 (en) 2016-01-29 2017-01-27 Storage container for a storage and dispensing station for pharmaceuticals
BR112018013692-1A BR112018013692B1 (pt) 2016-01-29 2017-01-27 Recipiente de armazenagem para estação de armazenagem e fornecimento de medicamentos
CA3012888A CA3012888A1 (en) 2016-01-29 2017-01-27 Storage container for a storage and delivery station for drugs
EP17701536.9A EP3407854A1 (de) 2016-01-29 2017-01-27 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel
KR1020187021602A KR102650781B1 (ko) 2016-01-29 2017-01-27 약품 보관 및 분배 스테이션을 위한 보관 용기
CN201780008028.1A CN108697582A (zh) 2016-01-29 2017-01-27 用于药物储配站的储存容器
AU2022203194A AU2022203194A1 (en) 2016-01-29 2022-05-12 Storage container for a storage and delivery station for drugs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16153271.8A EP3199141A1 (de) 2016-01-29 2016-01-29 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel
EP16153271.8 2016-01-29

Publications (1)

Publication Number Publication Date
WO2017129775A1 true WO2017129775A1 (de) 2017-08-03

Family

ID=55273142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/051821 WO2017129775A1 (de) 2016-01-29 2017-01-27 Vorratsbehälter für eine vorrats- und abgabestation für arzneimittel

Country Status (8)

Country Link
EP (2) EP3199141A1 (ja)
JP (1) JP7010829B2 (ja)
KR (1) KR102650781B1 (ja)
CN (1) CN108697582A (ja)
AU (2) AU2017212691A1 (ja)
BR (1) BR112018013692B1 (ja)
CA (1) CA3012888A1 (ja)
WO (1) WO2017129775A1 (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11491600B2 (en) * 2020-02-14 2022-11-08 In Touch Pharmaceuticals, Inc. System and method for on demand pill canister production

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3263866A (en) * 1964-09-14 1966-08-02 Walter E Proctor Instant coffee dispensing device
US5791526A (en) * 1993-12-20 1998-08-11 Moulinex S.A. Automatic ground matter dispenser
EP1617186A1 (de) * 2004-07-13 2006-01-18 Thomas Völkl Portioniervorrichtung
US20070034084A1 (en) * 2005-08-09 2007-02-15 O & S Development, Inc. Beverage preparation device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01167001A (ja) * 1987-12-11 1989-06-30 Tokyo Shokai:Kk 散薬定量取出装置
JP4298834B2 (ja) * 1999-01-14 2009-07-22 株式会社湯山製作所 錠剤フィーダ
US7516829B2 (en) * 2002-04-25 2009-04-14 Kite International Co., Ltd. Vending machine of encapsulated article of commerce
JP4398759B2 (ja) * 2004-03-03 2010-01-13 株式会社トーショー 薬剤フィーダおよびその集合体
KR100800290B1 (ko) * 2006-11-01 2008-02-01 (주)제이브이엠 약제 자동 포장기용 카세트 장치
NL2007384C2 (nl) 2011-09-09 2013-03-12 Ppm Engineering B V Systeem en werkwijze voor het verpakken van gedoseerde hoeveelheden vaste medicijnen.
KR101449717B1 (ko) * 2013-01-02 2014-10-15 주식회사 인포피아 약제 포장장치용 정제 카트리지
JP6172496B2 (ja) * 2013-01-30 2017-08-02 株式会社湯山製作所 薬剤フィーダ

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3263866A (en) * 1964-09-14 1966-08-02 Walter E Proctor Instant coffee dispensing device
US5791526A (en) * 1993-12-20 1998-08-11 Moulinex S.A. Automatic ground matter dispenser
EP1617186A1 (de) * 2004-07-13 2006-01-18 Thomas Völkl Portioniervorrichtung
US20070034084A1 (en) * 2005-08-09 2007-02-15 O & S Development, Inc. Beverage preparation device

Also Published As

Publication number Publication date
KR102650781B1 (ko) 2024-03-22
EP3199141A1 (de) 2017-08-02
JP2019503235A (ja) 2019-02-07
JP7010829B2 (ja) 2022-01-26
AU2017212691A1 (en) 2018-07-19
CN108697582A (zh) 2018-10-23
BR112018013692A2 (pt) 2018-12-04
BR112018013692B1 (pt) 2023-02-07
CA3012888A1 (en) 2017-08-03
AU2022203194A1 (en) 2022-06-02
EP3407854A1 (de) 2018-12-05
KR20180108621A (ko) 2018-10-04

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