WO2016205986A1 - Analyseur d'échantillon et procédé de commande associé - Google Patents

Analyseur d'échantillon et procédé de commande associé Download PDF

Info

Publication number
WO2016205986A1
WO2016205986A1 PCT/CN2015/082001 CN2015082001W WO2016205986A1 WO 2016205986 A1 WO2016205986 A1 WO 2016205986A1 CN 2015082001 W CN2015082001 W CN 2015082001W WO 2016205986 A1 WO2016205986 A1 WO 2016205986A1
Authority
WO
WIPO (PCT)
Prior art keywords
consumable
container
cache
drawer
consumables
Prior art date
Application number
PCT/CN2015/082001
Other languages
English (en)
Chinese (zh)
Inventor
高再兴
刘军华
Original Assignee
深圳迈瑞生物医疗电子股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳迈瑞生物医疗电子股份有限公司 filed Critical 深圳迈瑞生物医疗电子股份有限公司
Priority to PCT/CN2015/082001 priority Critical patent/WO2016205986A1/fr
Priority to CN201580079381.XA priority patent/CN107532979B/zh
Priority to CN202011356769.9A priority patent/CN112698046B/zh
Publication of WO2016205986A1 publication Critical patent/WO2016205986A1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor

Definitions

  • This application relates to the field of sample analysis, and more particularly to a sample analysis device for sample detection using disposable consumables.
  • a sample analysis device such as a chemiluminescence immunoassay analyzer uses a disposable reaction cup or the like for sample detection, and the number of loadings of the new reaction cup affects the continuous test of the whole machine test and the standby time.
  • the existing sample analysis device adds the cup box filled with the reaction cup to the machine at one time, and there are two disadvantages: 1. When a batch of tests is not finished but the new reaction cup is used, the whole machine must be suspended for testing and waiting for labor. After restarting the new cup box, restart the operation. If the replacement cup is long, the sample in the test may affect the sample test result, and even the test is invalid due to the interruption of the test, which increases the manual processing time and cost; After a batch of tests, there is a new reaction cup left in the cup box but the quantity is not enough to support the next batch of test ⁇ . The cup box needs to be replaced or replaced after the middle of use. It will also be due to the reaction cup during the test. The test is suspended after use, affecting the continuity of the test and the test results.
  • the present invention provides a new sample analysis device and a control method thereof.
  • the present invention provides a sample analysis device sample analysis device, including a body, a gripper capable of grasping consumables disposed in the body, and a transfer device capable of driving the gripper, the machine Having a loading position capable of mounting a consumable container having a plurality of first storage locations, the body further having a cache bit capable of mounting a consumable cache container having a plurality of second storage locations, the gripper having a cache The movement stroke, in the cache movement stroke, the gripper transfers the consumables in the first storage position to the second storage position.
  • the gripper can have a plurality of other strokes, including a stroke to transfer consumables in the first storage location to the reaction tray and a stroke to transfer consumables in the second storage location to the reaction tray.
  • the first storage location of each consumable container, the number of second storage locations of the consumable buffer container, and, preferably, is greater than the number of consumables required for a batch of tests.
  • the loading position has at least one consumable container, and the cache bit has at least one consumable cache container.
  • the load bit can also have at least two consumable containers; the cache bit can also have at least two consumable cache containers.
  • the consumable is a reaction cup.
  • the fuselage is provided with at least one drawer that is slidably engaged therewith, and the consumable container is loaded and
  • Each drawer can be fitted with one or at least two consumable containers.
  • the sample analysis device further includes a reaction disk disposed in the body, the drawer has two parallel to each other, and the consumable buffer container is fixed to the body and located between the rear end of the drawer and the reaction disk. .
  • a sample analysis device control method the sample analysis device is provided with a loading position capable of installing a consumable container, and the sample analysis device is further provided with a cache bit capable of installing a consumable cache container, and the method includes: a caching step, Dissipating consumables within the consumable container into the consumable buffer container.
  • the consumable container is normally locked, and the controlling method further comprises the following steps: detecting the quantity of the consumables in each consumable container, and when the quantity of the consumables in the consumable container is less than a predetermined value, releasing the consumable container The locking allows the consumable container to be removed for replacement.
  • Lock as electromagnetic lock.
  • the predetermined value is 0 or other preset value.
  • the consumable cache container is full or each of the consumable containers is empty, and the transfer is stopped.
  • the consumable container is replaceable and can be directly detachably mounted to the loading position.
  • the consumable container can also be mounted on a carrier that cooperates with the fuselage.
  • the carrier can be slidably engaged with the body, or can be rotated and fitted, and the carrier can be placed inside the fuselage; after the replacement, the carrier can be taken out from the inside of the fuselage.
  • the beneficial effects of the present invention are: Adding a setting of a consumable buffer container, fully utilizing the internal space of the analysis device under a limited operating space limitation, and supporting the replacement of the reaction cup in the test at a smaller space and cost Downtime, and the number of cuvettes available in the machine is more, the sustainability test after one cup is longer, the manual operation is reduced, and the test efficiency is improved.
  • FIG. 1 is a schematic perspective view showing the sample analysis device of the present embodiment
  • FIG. 2 is a schematic structural view of another perspective of the present embodiment
  • FIG. 3 is a schematic structural view of a consumable cache container of the present embodiment
  • FIG. 4 is a schematic structural view of a consumable container of the present embodiment.
  • the sample analysis device of the present invention is exemplified by an immunoanalyzer.
  • the immunoanalyzer adds a cuvette buffer position when the disposable storage space of the new cuvette is limited in the space layout of the whole machine, and the immunoanalyzer can With the loading position, one or more drawers can be installed in the loading position, and the consumable container can be installed in the drawer, so that the loading and unloading of the consumable container can be realized by pushing and pulling the drawer.
  • the storage capacity of the consumable container is designed to the maximum capacity according to the layout of the whole machine.
  • the size of the drawer directly determines the size of the consumable container. To avoid interference between the drawer and other components, it is necessary to limit the volume of the consumable container. The capacity of the consumable container is limited. To increase the capacity of the whole reaction cup, a fixed consumable buffer container is designed for this area. The addition of the cuvette buffer container allows the customer to replace the consumable container, and the number of cuvettes available in the machine is large. The sustainability test after the cup is completed for a longer period of time, reducing manual and frequent operations.
  • the immunoanalyzer includes a body 9, a reaction disk 10, a gripper 4, and a transfer device 11.
  • the reaction disk 10 is rotatably disposed in the body 9.
  • the transfer device 11 drives the gripper 4 to grab the consumables and realize the transfer of consumables between different stations, such as the existing gripper robot.
  • the body 9 is provided with a loading position, and the loading position is provided with two drawers slidingly matched with the body.
  • the two drawers are respectively defined as a first drawer 1 and a second drawer 2, and each drawer is provided with a consumable container 5,
  • Each consumable container 5 has a plurality of first storage locations 12 that can accommodate the cuvette 8, such as a conventional cup cartridge.
  • a cache bit is also fixed to the body 9, and a cache buffer container 6 is mounted in the cache position.
  • the consumable buffer container 6 has a plurality of second storage locations 13 capable of accommodating the cuvette.
  • a consumable container can also be set in one drawer, or multiple consumable containers can be set.
  • the front of the fuselage facing the operator is provided with a front door 3 that can be opened and closed, two drawers are juxtaposed at the front, and the consumable buffer container 6 is located at the rear of the two drawers and other components of the immunoanalyzer Between 7, Located between the drawer and the reaction tray 10.
  • the front door 3 is smashed, the first drawer 1 and the second drawer 2 are respectively pulled out and put into the cup box as a consumable container, and the two drawers are pushed in, the ⁇ cup box is filled with the reaction cup, the consumable buffer container 6 no reaction cup, the gripper 4 is located above the cup box.
  • the cup of the first drawer 1 or the second drawer 2 is prepared to be replaced.
  • Snoring the front door 3, manually pulling out the first drawer 1 or the second drawer 2 if the drawer cannot be pulled out, the first drawer reaction cup button or the second drawer reaction cup button in the software interface can be manually clicked, and then Click the load icon to pull out the corresponding first drawer 1 or the second drawer 2, take the empty cup box in the first drawer 1 or the second drawer 2, and put the cup box carrying the full-box reaction cup 8
  • the first drawer 1 or the second drawer 2 is pushed in again, and the system automatically displays the cuvette balance of the first drawer 1 or the second drawer 2 as the maximum capacity value of the cup, and closes the process in which the front door 3 completes the change of the number of the cups.
  • the gripper preferentially grabs the reaction cup on the consumable buffer container, and then grabs the second drawer cup box in turn after the consumable buffer container reaction cup is used.
  • the upper cuvette is used, and finally the cuvette in the first drawer cup box is grasped.
  • the system automatically performs the gripping of the cuvette on the cup box into the consumable buffer container until the consumable buffer container There are no new cuvettes in the full or two cups.
  • the grabber is idle, and the grabber first transfers the cuvette from the load position to the cache bit buffer for use; during the test, the load position is used first.
  • Cup when the loading position reaction cup is used up, the operator is directly prompted to replace the consumable container, and a new reaction cup is added, and the cuvette used for the test is taken from the buffer position, thereby ensuring that the test is not interrupted during the replacement of the consumable container.
  • Continuous continuous testing the same can be added before the downtime test, a larger number of cuvettes can be added at a time than the conventional instrument (the cache bit is also filled) to increase the test off-site, to meet more test Cup demand.
  • the grabber idle time refers to the time when the grabber is in a static waiting state.
  • Cache time means: The picker starts at the current position and transfers the new cuvette in the consumable container to the time required for the consumable cache container.
  • the system compares the cache time and the crawler idle time. If the cache time is smaller than the crawler idle time, the cache operation is performed, that is, the crawler transfers the reaction cup from the consumable container to the consumable cache container. The remaining amount of the consumable buffer container is increased by 1; until the consumable buffer container is full (ie, the remaining amount reaches the set value), and then the conventional gripping operation is performed, that is, the new reaction cup is directly transferred to the consumable container.
  • the gripper can set the sensor, operate the crucible, the gripper grabs the cuvette and lowers the cuvette, the state of the sensor changes, and the change is counted.
  • a consumable container and a consumable buffer container can hold a consumable that is discarded after use in the test cartridge and including after use, including but not limited to a cuvette, a flow tube, or a TIP head, typically a tubular structure
  • the consumable container and the cache container may have matching hole-shaped storage positions.
  • a consumable buffer container is added between the existing consumable container and the existing reaction tray, and continuous sample testing between long turns is realized.
  • the consumable buffer container can also be flexibly placed elsewhere in the immunoanalyzer, such as an immunoassay analyzer and a magnetic separation disc.
  • the consumable buffer container can also be placed between the consumable container and the magnetic separation disc.
  • the sample analysis device of the present invention may be an immunoanalyzer or a sample analysis device for sample processing such as a biochemical analyzer.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

La présente invention concerne un analyseur d'échantillon et un procédé de commande de celui-ci. L'analyseur d'échantillon comprend : un corps d'appareil (9), un dispositif de préhension (4) prévu au niveau du corps d'appareil (9) et capable de saisir un matériau et un dispositif de transfert (11) capable d'entraîner le déplacement du dispositif de préhension (4). Le corps d'appareil (9) est doté d'une position de chargement au niveau de laquelle peut être installé un contenant de matériau (5) comprenant une pluralité de premières positions de stockage (12), et d'une position tampon au niveau de laquelle peut être installé un récipient tampon de matériau (6) comprenant une pluralité de deuxièmes positions de stockage (13). Le dispositif de préhension (4) possède un processus de transfert tampon, le dispositif de préhension (4) faisant passer le matériau de la première position de stockage (12) à la seconde position de stockage (13). Par l'ajout d'un récipient de matériau tampon, après le chargement de remplacement par un client de réacteurs, un grand nombre de réacteurs peut être prévu pour être utilisés dans l'appareil, permettant une augmentation du temps de test continu après chargement de la totalité de l'appareil, réduisant la fréquence de fonctionnement manuel et augmentant l'efficacité de test.
PCT/CN2015/082001 2015-06-22 2015-06-22 Analyseur d'échantillon et procédé de commande associé WO2016205986A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/CN2015/082001 WO2016205986A1 (fr) 2015-06-22 2015-06-22 Analyseur d'échantillon et procédé de commande associé
CN201580079381.XA CN107532979B (zh) 2015-06-22 2015-06-22 样本分析装置及其控制方法
CN202011356769.9A CN112698046B (zh) 2015-06-22 2015-06-22 样本分析装置及其控制方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2015/082001 WO2016205986A1 (fr) 2015-06-22 2015-06-22 Analyseur d'échantillon et procédé de commande associé

Publications (1)

Publication Number Publication Date
WO2016205986A1 true WO2016205986A1 (fr) 2016-12-29

Family

ID=57586567

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2015/082001 WO2016205986A1 (fr) 2015-06-22 2015-06-22 Analyseur d'échantillon et procédé de commande associé

Country Status (2)

Country Link
CN (2) CN107532979B (fr)
WO (1) WO2016205986A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020243988A1 (fr) 2019-06-06 2020-12-10 深圳传世生物医疗有限公司 Système d'analyse d'échantillons et son procédé de commande, et procédé d'analyse d'échantillons

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107532979B (zh) * 2015-06-22 2020-12-22 深圳迈瑞生物医疗电子股份有限公司 样本分析装置及其控制方法
CN109557325B (zh) * 2017-09-27 2023-02-28 深圳市新产业生物医学工程股份有限公司 医用耗材存储盒加载装置的扫描检测装置及方法
CN107807249B (zh) * 2017-10-26 2024-05-24 迈克医疗电子有限公司 解锁组件、样本转移装置及其控制方法
CN112858709A (zh) * 2021-01-18 2021-05-28 桂林优利特医疗电子有限公司 一种化学发光免疫分析仪抓吸一体机构及使用方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102221624A (zh) * 2010-04-14 2011-10-19 深圳迈瑞生物医疗电子股份有限公司 样本架传送系统及生化分析仪
CN102955040A (zh) * 2011-08-26 2013-03-06 希森美康株式会社 样本分析装置
WO2013034937A1 (fr) * 2011-09-08 2013-03-14 Diagon Kft. Procédé pour déplacer des râteliers de récipients d'échantillon et équipement dans ce but
CN104108603A (zh) * 2013-04-16 2014-10-22 深圳迈瑞生物医疗电子股份有限公司 一种杯盒抓取机构及方法
CN104569462A (zh) * 2013-10-15 2015-04-29 深圳迈瑞生物医疗电子股份有限公司 一种样本容器的搬送装置及方法
CN104569461A (zh) * 2013-10-15 2015-04-29 深圳迈瑞生物医疗电子股份有限公司 样本架运送装置及流水线和运送方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4210963A1 (de) * 1992-04-02 1993-10-07 Baxter Deutschland Automatische Vorrichtung zur photometrischen Analyse von flüssigen Proben
US6266436B1 (en) * 1999-04-09 2001-07-24 Kimberly-Clark Worldwide, Inc. Process control using multiple detections
KR20050105830A (ko) * 2004-05-03 2005-11-08 매그나칩 반도체 유한회사 반도체 장치의 제조에 사용되는 케미컬 제공 장치
JP2010139370A (ja) * 2008-12-11 2010-06-24 Beckman Coulter Inc ラックトレイ、ラックおよびラック搬送システム
CN103018470B (zh) * 2011-09-27 2015-02-04 希森美康株式会社 样本分析装置
US20140273088A1 (en) * 2011-10-17 2014-09-18 Victorious Medical Systems Aps Method, apparatus and system for staining of biological samples
AU2013266026A1 (en) * 2012-05-25 2014-12-11 Technological Resources Pty. Limited Analysis system and associated method of handling and analysing discrete mineral samples
ITMI20120975A1 (it) * 2012-06-05 2013-12-06 Inpeco Ip Ltd Apparato di interfacciamento tra un impianto di automazione di laboratorio e una piattaforma per la movimentazione di consumabili e liquidi nell'ambito della biologia molecolare.
EP2759988A1 (fr) * 2013-01-28 2014-07-30 Dansk Retursystem A/S Station de recyclage
ES2904524T3 (es) * 2013-10-07 2022-04-05 Eppendorf Ag Instrumento de laboratorio, sistema y método para el procesamiento controlado por el instrumento de al menos una muestra de laboratorio mediante el uso de al menos un consumible
CN203561641U (zh) * 2013-11-28 2014-04-23 博奥赛斯（天津）生物科技有限公司 化学发光免疫分析仪结构
CN107532979B (zh) * 2015-06-22 2020-12-22 深圳迈瑞生物医疗电子股份有限公司 样本分析装置及其控制方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102221624A (zh) * 2010-04-14 2011-10-19 深圳迈瑞生物医疗电子股份有限公司 样本架传送系统及生化分析仪
CN102955040A (zh) * 2011-08-26 2013-03-06 希森美康株式会社 样本分析装置
WO2013034937A1 (fr) * 2011-09-08 2013-03-14 Diagon Kft. Procédé pour déplacer des râteliers de récipients d'échantillon et équipement dans ce but
CN104108603A (zh) * 2013-04-16 2014-10-22 深圳迈瑞生物医疗电子股份有限公司 一种杯盒抓取机构及方法
CN104569462A (zh) * 2013-10-15 2015-04-29 深圳迈瑞生物医疗电子股份有限公司 一种样本容器的搬送装置及方法
CN104569461A (zh) * 2013-10-15 2015-04-29 深圳迈瑞生物医疗电子股份有限公司 样本架运送装置及流水线和运送方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020243988A1 (fr) 2019-06-06 2020-12-10 深圳传世生物医疗有限公司 Système d'analyse d'échantillons et son procédé de commande, et procédé d'analyse d'échantillons
US12007401B2 (en) 2019-06-06 2024-06-11 Shenzhen Thistory Bio-Medical Co., Ltd Sample analysis system and control method for the same and sample analysis method

Also Published As

Publication number Publication date
CN112698046B (zh) 2024-01-30
CN107532979A (zh) 2018-01-02
CN107532979B (zh) 2020-12-22
CN112698046A (zh) 2021-04-23

Similar Documents

Publication Publication Date Title
WO2016205986A1 (fr) Analyseur d'échantillon et procédé de commande associé
JP4500822B2 (ja) 自動分析装置
JP6169337B2 (ja) 検体検査自動化システムおよび検体の搬送方法
US10234364B2 (en) Sample processing apparatus and rack
WO2019183745A1 (fr) Analyseur de chimiluminescence et son procédé d'analyse
WO2018155049A1 (fr) Analyseur automatique
JP5808634B2 (ja) 検体処理装置
JPWO2012043261A1 (ja) 検体検査自動化システムおよびその制御方法
JP6837362B2 (ja) 自動分析装置
WO2016017289A1 (fr) Appareil d'analyse automatique
JP2015087306A (ja) 検体容器取出装置及び検体処理システム
US20180340948A1 (en) Device for agitating and collecting liquid samples
US12005409B2 (en) Device for agitating and collecting biological liquid samples suitable for sorting
US9052301B2 (en) Automatic analyzer
JP2008122417A (ja) 自動分析装置
EP2530470A1 (fr) Dispositif d'analyse automatique
JP6710558B2 (ja) 検体搬送システムおよび検体検査システム
JP2011257427A (ja) 自動分析装置
JP2008039552A (ja) 検体搬送システム
JP5276189B2 (ja) マイクロプレート用ピックアップ装置、及びマイクロプレート供給回収装置
CN213933889U (zh) 样本分析仪
JP7292098B2 (ja) 検体用トレイと検体検査自動化システム
JP5638024B2 (ja) 検体搬送システム
JP7402891B2 (ja) 使い捨てピペットチップの管理
CN116413094A (zh) 显示方法、样本处理装置及包含可执行程序的存储介质

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 15895886

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC - FORM 1205A (18.05.2018)

122 Ep: pct application non-entry in european phase

Ref document number: 15895886

Country of ref document: EP

Kind code of ref document: A1