WO2013034937A1 - Procédé pour déplacer des râteliers de récipients d'échantillon et équipement dans ce but - Google Patents

Procédé pour déplacer des râteliers de récipients d'échantillon et équipement dans ce but Download PDF

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Publication number
WO2013034937A1
WO2013034937A1 PCT/HU2012/000042 HU2012000042W WO2013034937A1 WO 2013034937 A1 WO2013034937 A1 WO 2013034937A1 HU 2012000042 W HU2012000042 W HU 2012000042W WO 2013034937 A1 WO2013034937 A1 WO 2013034937A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample container
container racks
sample
movable tray
sampling
Prior art date
Application number
PCT/HU2012/000042
Other languages
English (en)
Inventor
Kornél Nagy
Original Assignee
Diagon Kft.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagon Kft. filed Critical Diagon Kft.
Publication of WO2013034937A1 publication Critical patent/WO2013034937A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system

Definitions

  • the invention relates to a procedure for moving sample container racks, and equipment for realising the procedure.
  • automated analyzers by arranging and moving sample container racks according to the invention our aim is to perform sampling operations suiting tests of varying numbers and also repeated sampling operations in a quick and simple way.
  • test sample/samples and test reagent/reagents appropriate for the test is essential when measuring a given parameter, phenomenon or reaction at the measuring points of automated analyzers.
  • Most commonly the necessary supply of test reagent/reagents is solved by using reagent tanks calibrated for high detection numbers and reagent-dispensing structures.
  • the heterogeneous origin often characteristic of test samples and the varying demand of test numbers must be taken into consideration. Considering this, different solutions aimed at moving sample container racks in automated analyzers have been elaborated.
  • sample tube is a cylindrical or prism-shaped vessel containing the test sample, mostly made of glass or transparent plastic, closed at one end and lockable at the other end, which may be, for example, a tube or vial.
  • the test sample may be a liquid or solid organic or inorganic material.
  • sample container racks according to our invention are used for placing and storing sample tube/tubes described above.
  • Structures guiding and moving sample container racks are generally fitted at the front of automated analyzers. It is a general feature that after automated identification the guiding and moving structure forwards the sample container racks one after the other from the input position to the sampling position of the device, and after sampling and carrying out an assessable test it moves them out of there [for details see patent specifications EP 2299279A2 and EP 2256502A1]. If a repeated test is required, the guiding and moving structure moves the sample container racks as above again.
  • a magnetic guide operated at the bottom of a stable input tray forwards the sample container racks one by one from the input tray to the sampling position of the device. After sampling, the sample container racks are returned from the sampling position by power control.
  • An advantage of the system is that due to the magnetic movement of the sample container racks the content of the sample tubes can be preserved without any loss until sampling.
  • a disadvantage of the system is that it only works with sample container racks with magnets.
  • a further disadvantage of the system is that the movement of the sample container racks is unidirectional.
  • the disadvantage of the above systems is that the retesting of the test samples as required is relatively slow, because the sample container racks can only be accessed one after the other, and racks that do not contain sample tubes to be retested are also moved.
  • Our aim with the solution according to the invention is to eliminate the unfavourable characteristics of the existing systems described above in detail, and to create a solution with which sample container racks in automated analyzers are moved in more than one direction for performing a varying number of tests and, if required, repeated sampling is also realised in a quick and simple way.
  • our procedure according to the invention we present the movement of sample container racks according to our procedure in an automated blood coagulation analyzer for in vitro diagnostic use, adding that our procedure can be extended to any other automated analyzer.
  • the movable tray accommodating the sample container racks is favourably moved forwards and backwards along an x axis.
  • the simplest way of forwarding one of the sample container racks as required to the sampling position at the time required is to push one of the sample container racks as required - in the preferred position of the tray moved forwards and backwards along an x axis - towards the sampling position along a y axis at right angles to the direction of movement of the movable tray, and move it in and out as necessary.
  • the sample tube/sample tubes selected for testing and situated in the sample container rack selected as required is/are forwarded to the sampling position.
  • the sample container rack pushed towards the sampling position is removed in such a way that it is returned along the y axis at right angles to the direction of movement of the movable tray, i.e. it is pushed onto the movable tray.
  • Our invention relates to a procedure for moving sample container racks, in the course of which sample tubes containing test samples are placed in sample container racks and forwarded to the sampling position of an automated analyzer, and after sampling they are returned from the sampling position.
  • the procedure is based on that the sample container racks are arranged on a movable tray moving in a given direction - favourably direction x - in open lines favourably fixed in direction y.
  • the sample container racks arranged in fixed lines, together with the movable tray, are moved forwards/backwards along an x axis, and one of the simultaneously moved sample container racks selected as required is brought into a preferred position with the movable tray.
  • one of the sample container racks selected as required is pushed along a y axis from the movable tray towards the sampling position, the pushed out sample container rack is moved forwards/backwards along the y axis, as a result of which the required sample tube(s) is (are) pushed to the sampling position of the automated analyzer.
  • one of the sample container racks selected as required is returned from the sampling position onto the movable tray.
  • sample tubes filled with test samples are arranged in sample container racks suitable for accommodating at least two sample tubes.
  • the number of sample container racks arranged in lines, favourably fixed lines, on the tray movable along the x axis is at least two, most favourably it is not below ten.
  • the forwards and backwards movement of the movable tray along the x axis is realised with the help of a moving device and a mechanism driving this device, most favourably on parallel tracks suiting the size of the tray.
  • one of the simultaneously moved sample container racks selected as required is brought into a preferred position along the x axis, with the movable tray.
  • the sample container rack in a preferred position is pushed out first for the purpose of sampling with a pushing device and its drive mechanism operated along a y axis at right angles to the direction of movement of the movable tray, and then the sample tube(s) is (are) moved in and out of the sampling position, and finally they are pushed in and returned onto the movable tray.
  • the invention relates to equipment for moving sample container racks simultaneously, which equipment has sample container racks, a tray accommodating them, a device moving the tray and a mechanism driving the device.
  • the equipment is constructed in such a way that the sample container racks contain sample tubes filled with test samples, the sample container racks containing the sample tubes are arranged on the movable tray in fixed lines open at least on one side.
  • Parallel tracks, a moving device and a drive mechanism are constructed for moving the movable tray forwards and backwards along the x axis at right angles to its fixed lines.
  • a pushing device with a further drive mechanism operated along the y axis at right angles to the direction of movement of the movable tray is constructed for pushing out one of the sample container racks selected as required from its fixed line in its preferred position.
  • the sampling position it contains a sampling arm for taking samples from the sample tubes.
  • FIG. 1 shows the plan of a possible embodiment of the sample container rack
  • FIG. 1 shows a favourable embodiment of the sample tube 22, and, for example, in the possible version shown in the figure the sample container rack 23 for accommodating sample tubes 22 is suitable for storing ten sample tubes 22.
  • the sample tubes 22 are arranged in the sample container rack 23 in a line.
  • Figure 2 shows a possible embodiment of the equipment in top view. It can be seen in the figure that the equipment according to the invention has sample container racks 23, a movable tray 24 accommodating them, a moving device 27 connected to the movable tray 24, and a drive mechanism M7, which is covered in figure 2, see figure 3.
  • the sample container racks 23 contain sample tubes 22 filled with test samples.
  • the sample container racks 23 containing sample tubes 22 are arranged on the movable tray 24 in fixed lines 24A open at least on one side.
  • Parallel tracks 29, a moving device 27 and a drive mechanism M7 are constructed for moving the movable tray 24 forwards and backwards along the x axis at right angles to its fixed lines 24A.
  • a pushing device 28 with a further drive mechanism M8 operated along the y axis at right angles to the direction of movement of the movable tray 24 is constructed for pushing out one of the sample container racks 23 selected as required from its fixed line 24 A in its preferred position 25.
  • the sampling position 26 it contains a sampling arm MK for taking samples from the sample tube(s) 22.
  • FIG 3 the status of a possible solution of the equipment as in figure 2 is shown in lateral view.
  • the figure it can be seen that after bringing one of the sample container racks arranged in fixed lines 24A (not possible to show in lateral view) into a preferred position 25 (not possible to show in lateral view) on the movable tray 24, on parallel tracks 29, along the x axis, with the help of the moving device 27 and its drive mechanism M7, it is pushed towards the sampling position 26 with the help of the pushing device 28 and its drive mechanism M8 operated along the y axis at right angles to the movement of the movable tray 24. After this a sample is taken from the sample tube 22 at the sampling position 26.
  • the invention also relates to equipment for the realisation of the procedure according to the invention.
  • a possible version of the equipment according to our invention is constructed in such a way that it has sample container racks containing samples tubes (figure 1), a movable tray accommodating the sample container racks in lines, a device moving the movable tray with a drive mechanism, a device pushing the sample container rack in and out and its drive mechanism (figures 2, 3).
  • sample tubes 22 filled with test samples are placed in the sample container racks 23.
  • the sample container racks 23 containing the sample tubes 22 are arranged on the movable tray 24 favourably in fixed lines 24A.
  • the movable tray 24 is moved forwards and backwards along the x axis together with the sample container racks 23 arranged in fixed lines 24A, favourably on parallel tracks 29, with the help of a moving device 27 and its drive mechanism M7.
  • the sample container rack 23 is brought into a preferred position 25 favourably at the desired frequency.
  • a further favourable characteristic feature of the equipment is that the sample container racks 23 brought into a preferred position 25 is pushed out from the movable tray 24 towards the sampling position 26 with the help of a pushing device 28 and its drive mechanism M8 operated along a y axis at right angles to the direction of movement of the movable tray 24.
  • the sample container rack 23 pushed out with the help of the pushing device 28 and its drive mechanism M8 is also moved forwards and backwards by the same pushing device 28 and its drive mechanism M8 in order to forward the required sample tube/sample tubes 22 to the sampling position 26 of the automated analyzer.
  • the required sample tube(s) 22 are forwarded to the sampling position 26 of the automated analyzer, and after sampling the sample container rack 23 is returned from the sampling position 26 onto the movable tray 24.
  • sample container racks 23 containing sample tubes 22 filled with test samples are forwarded to the sampling position 26 and returned from the sampling position 26 in a quick and simple way, as a result of which in automated analyzers sampling operations suiting tests of varying numbers and also repeated sampling operations are realised in a quick, cost-efficient and simple way.

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention porte sur un équipement pour déplacer des râteliers de récipients d'échantillon simultanément, lequel équipement a des râteliers de récipients d'échantillon, un plateau mobile les recevant, un dispositif déplaçant le plateau et un mécanisme entraînant le dispositif. L'équipement est construit de telle manière que les râteliers de récipients d'échantillon (23) contiennent des tubes d'échantillon (22) remplis par des échantillons de test, les râteliers de récipients d'échantillon (23) contenant les tubes d'échantillon (22) étant disposés sur le plateau mobile (24) par lignes fixes (24A) ouvertes au moins sur un côté. Des pistes parallèles (29), un dispositif mobile (27) et un mécanisme d'entraînement (M7) sont construits pour déplacer le plateau mobile (24) vers l'avant et vers l'arrière le long de l'axe x à angles droits par rapport à ses lignes fixes (24A). Un dispositif de poussée (28) muni d'un autre mécanisme d'entraînement (M8) actionné le long de l'axe y à angles droits par rapport à la direction de mouvement du plateau mobile (24) est construit pour pousser vers l'extérieur l'un des râteliers de récipients d'échantillon (23) sélectionné selon les besoins à partir de sa ligne fixe (24A) dans sa position préférée (25). De plus, dans la position d'échantillonnage (26), il contient un bras d'échantillonnage (MK) pour prendre des échantillons à partir des tubes d'échantillon (22). L'invention porte également sur un procédé pour déplacer des râteliers de récipients d'échantillon, au cours duquel des tubes d'échantillon contenant des échantillons de test sont disposés dans des râteliers de récipients d'échantillon et envoyés dans la position d'échantillonnage d'un analyseur automatique, et, après l'échantillonnage, ils sont renvoyés à partir de la position d'échantillonnage.
PCT/HU2012/000042 2011-09-08 2012-05-24 Procédé pour déplacer des râteliers de récipients d'échantillon et équipement dans ce but WO2013034937A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP1100493 2011-09-08
HU1100493A HUP1100493A2 (en) 2011-09-08 2011-09-08 Method and device for conveying sample stands

Publications (1)

Publication Number Publication Date
WO2013034937A1 true WO2013034937A1 (fr) 2013-03-14

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HU (1) HUP1100493A2 (fr)
WO (1) WO2013034937A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103698546A (zh) * 2014-01-21 2014-04-02 中国科学院苏州生物医学工程技术研究所 全自动化学发光免疫分析仪的吸样头连续装载及卸载机构
WO2016205986A1 (fr) * 2015-06-22 2016-12-29 深圳迈瑞生物医疗电子股份有限公司 Analyseur d'échantillon et procédé de commande associé
CN107533074A (zh) * 2015-06-22 2018-01-02 深圳迈瑞生物医疗电子股份有限公司 一种样本分析装置
CN108414776A (zh) * 2018-05-04 2018-08-17 长春市布拉泽医疗科技有限公司 一种高效率推片装置
CN110873805A (zh) * 2018-08-31 2020-03-10 深圳市帝迈生物技术有限公司 一种传送设备及其传送方法、样本分析仪
USD907465S1 (en) 2019-03-07 2021-01-12 Gen-Probe Incorporated Serpentine retainer spring for a receptacle rack
USD907987S1 (en) 2019-03-07 2021-01-19 Gen-Probe Incorporated Serpentine retainer spring for a receptacle rack
US11511283B2 (en) 2019-03-07 2022-11-29 Gen-Probe Incorporated Carrier for holding a plurality of multi-receptacle units

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EP0753747B1 (fr) 1995-07-14 2004-09-29 Bayer Corporation Système de manutention des supports d'éprouvettes
EP2177912A2 (fr) 2008-10-15 2010-04-21 Sysmex Corporation Système de traitement de spécimens et procédé de transport de spécimens
EP2256502A1 (fr) 2008-02-29 2010-12-01 ARKRAY, Inc. Dispositif de transport pour analyseur, système d'analyse et connecteur destiné au dispositif de transport
EP2299279A2 (fr) 2009-09-17 2011-03-23 Sysmex Corporation Appareil de traitement d'échantillons et procédé de traitement de portoir d'échantillons
EP2357480A1 (fr) * 2008-12-11 2011-08-17 Beckman Coulter, Inc. Plateau à portoirs, portoir et système de transport de portoirs

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US3985507A (en) * 1975-09-05 1976-10-12 International Business Machines Corporation Automatic test sample handling system
US4387991A (en) * 1978-08-01 1983-06-14 Gilford Instrument Laboratories, Inc. Automatic monochromatic light absorbance measurement analyzer
JPS63281057A (ja) * 1987-05-13 1988-11-17 Toshiba Corp サンプラ−装置
EP0753747B1 (fr) 1995-07-14 2004-09-29 Bayer Corporation Système de manutention des supports d'éprouvettes
US6588625B2 (en) 2001-04-24 2003-07-08 Abbott Laboratories Sample handling system
EP2256502A1 (fr) 2008-02-29 2010-12-01 ARKRAY, Inc. Dispositif de transport pour analyseur, système d'analyse et connecteur destiné au dispositif de transport
EP2177912A2 (fr) 2008-10-15 2010-04-21 Sysmex Corporation Système de traitement de spécimens et procédé de transport de spécimens
EP2357480A1 (fr) * 2008-12-11 2011-08-17 Beckman Coulter, Inc. Plateau à portoirs, portoir et système de transport de portoirs
EP2299279A2 (fr) 2009-09-17 2011-03-23 Sysmex Corporation Appareil de traitement d'échantillons et procédé de traitement de portoir d'échantillons

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103698546A (zh) * 2014-01-21 2014-04-02 中国科学院苏州生物医学工程技术研究所 全自动化学发光免疫分析仪的吸样头连续装载及卸载机构
US11137411B2 (en) 2015-06-22 2021-10-05 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Sample analyzer
WO2016205986A1 (fr) * 2015-06-22 2016-12-29 深圳迈瑞生物医疗电子股份有限公司 Analyseur d'échantillon et procédé de commande associé
CN107533074A (zh) * 2015-06-22 2018-01-02 深圳迈瑞生物医疗电子股份有限公司 一种样本分析装置
EP3312614A4 (fr) * 2015-06-22 2019-06-05 Shenzhen Mindray Bio-Medical Electronics Analyseur d'échantillon
US11639942B2 (en) 2015-06-22 2023-05-02 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Sample analyzer
US20210382081A1 (en) * 2015-06-22 2021-12-09 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Sample analyzer
CN108414776A (zh) * 2018-05-04 2018-08-17 长春市布拉泽医疗科技有限公司 一种高效率推片装置
CN108414776B (zh) * 2018-05-04 2023-08-22 长春市布拉泽医疗科技有限公司 一种高效率推片装置
CN110873805A (zh) * 2018-08-31 2020-03-10 深圳市帝迈生物技术有限公司 一种传送设备及其传送方法、样本分析仪
USD907987S1 (en) 2019-03-07 2021-01-19 Gen-Probe Incorporated Serpentine retainer spring for a receptacle rack
USD907465S1 (en) 2019-03-07 2021-01-12 Gen-Probe Incorporated Serpentine retainer spring for a receptacle rack
US11511283B2 (en) 2019-03-07 2022-11-29 Gen-Probe Incorporated Carrier for holding a plurality of multi-receptacle units

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