WO2015002011A1 - Unité de gestion d'injection-mélange, dispositif d'injection-mélange et programme de gestion d'injection-mélange - Google Patents

Unité de gestion d'injection-mélange, dispositif d'injection-mélange et programme de gestion d'injection-mélange Download PDF

Info

Publication number
WO2015002011A1
WO2015002011A1 PCT/JP2014/066611 JP2014066611W WO2015002011A1 WO 2015002011 A1 WO2015002011 A1 WO 2015002011A1 JP 2014066611 W JP2014066611 W JP 2014066611W WO 2015002011 A1 WO2015002011 A1 WO 2015002011A1
Authority
WO
WIPO (PCT)
Prior art keywords
drug
medicine
mixed injection
container
remaining
Prior art date
Application number
PCT/JP2014/066611
Other languages
English (en)
Japanese (ja)
Inventor
幸久 吉屋
Original Assignee
株式会社湯山製作所
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社湯山製作所 filed Critical 株式会社湯山製作所
Priority to JP2014549843A priority Critical patent/JP5696822B1/ja
Publication of WO2015002011A1 publication Critical patent/WO2015002011A1/fr

Links

Images

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H70/00—ICT specially adapted for the handling or processing of medical references
    • G16H70/40—ICT specially adapted for the handling or processing of medical references relating to drugs, e.g. their side effects or intended usage
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like

Definitions

  • the present invention relates to a control technique for a co-infusion apparatus that executes co-infusion processing for injecting a drug such as an anticancer drug contained in a drug container into an infusion container.
  • co-infusion apparatus that performs a co-infusion process in which a drug such as an anticancer drug contained in a drug container such as an ampoule or a vial is sucked with a syringe and the drug is injected into an infusion bag containing the infusion solution.
  • a drug such as an anticancer drug contained in a drug container such as an ampoule or a vial
  • co-infusion processing is performed in a safety cabinet set to a negative pressure in order to prevent exposure to chemicals such as anticancer agents.
  • a predetermined amount of medicine predetermined for each medicine is stored in one medicine container, and the user can use one or more medicine containers satisfying the amount of medicine to be dispensed indicated in the preparation data in the co-infusion apparatus. Load it.
  • an object of the present invention is to provide a mixed injection management device, a mixed injection device, and a mixed injection management program capable of supporting efficient use of a medicine in a medicine container containing a predetermined amount of medicine.
  • the mixed injection management apparatus includes a determination unit and a display control unit. Whether the drug remains in the drug container used in the mixed injection process in which the drug indicated in the preparation data is injected from one or a plurality of drug containers containing the predetermined amount of the drug into the infusion container. Judge whether or not.
  • the display control means uses, as a prescription drug, a medicine of the same type as the remaining medicine determined to remain in the medicine container in the past mixed injection processing by the determination means among the selection candidates of the preparation data to be subjected to the mixed injection processing.
  • the prepared preparation data is preferentially displayed on the display means. According to the present invention, it is possible to make a user aware of the preparation data capable of using the remaining medicine as a target of the next mixed injection process, and to support efficient use of the medicine in the medicine container. be able to.
  • the mixed injection management device selects the preparation data including the same type of drug as the remaining drug in the prescription drug as a target of the mixed injection process and satisfies a preset use condition
  • the residual drug in the mixed injection process A configuration including a remaining medicine using means for using a medicine is conceivable. This makes it possible to automatically exclude the use of the remaining medicine when the use conditions are not satisfied.
  • the use condition includes at least that the expiration date set in advance for the remaining medicine has not passed. Thereby, for example, it is possible to set as the use condition that the expiration date of the remaining drug has not passed, and to set only the remaining drug for which the expiration date has not passed as the target of use.
  • the mixed injection management device includes a remaining amount detecting unit that detects the remaining amount of the remaining medicine in the medicine container after the mixed injection processing is performed.
  • the use condition is calculated based on the preparation data and the predetermined amount of the drug container.
  • the remaining amount of the remaining drug in the drug container and the remaining amount in the drug container detected by the remaining amount detecting means It is conceivable that the difference from the remaining amount of the remaining drug is within a preset range. Thereby, the difference between the remaining amount of the remaining drug actually remaining in the drug container and the calculated value of the remaining amount based on the preparation data and the predetermined amount of the drug container exceeds a predetermined allowable amount. In some cases, the use of the remaining drug is prevented.
  • the determination means determines whether or not the medicine remains in the medicine container based on the preparation data and the predetermined amount of the medicine container before execution of the mixed injection process.
  • the display control means can preferentially display the preparation data that can use the remaining medicine among the preparation data selection candidates before the end of the past mixed injection process.
  • the mixed injection management device includes a remaining amount detecting unit that detects the weight of the remaining medicine in the drug container after the mixed injection process is performed
  • the determination unit is detected by the remaining amount detecting unit. It is also conceivable to determine whether or not the medicine remains in the medicine container based on the remaining amount of the remaining medicine in the medicine container. In this case, the display control means preferentially displays the preparation data that can use the remaining medicine based on the remaining amount of the remaining medicine actually remaining in the medicine container after the mixed injection process.
  • the display control means causes the display means to display selection candidates for the preparation data in a display order in which the preparation data including the same kind of drug as the remaining medicine in the prescription drug is in the upper rank. Thereby, the user can grasp
  • the display control means may display the preparation data including the same kind of drug as the remaining drug as a prescription drug in the selection candidate of the preparation data to be the target of the mixed injection process, arranged in a preset sort condition. It is done. Thereby, the user can easily grasp the preparation data having a higher priority among the preparation data in which the remaining drug can be used according to the sorting condition.
  • the sorting condition is a condition in which the one with the earlier prescription drug dosing date or preparation date in the preparation data is higher.
  • the sort condition may be a condition in which the prescription category of the preparation data is outpatient than the case where the prescription category of the preparation data is hospitalization.
  • the user can easily grasp the order of the dispensing data to be prioritized according to the medication date and time, the preparation date and time, the prescription classification, and the like.
  • the said mixed injection management apparatus is provided with the predetermined amount information memory
  • the determination means determines whether or not the drug remains in the drug container based on the dispensed amount of the drug based on the preparation data and the predetermined amount information stored in the predetermined amount storage unit. Is possible.
  • the mixed injection management device stores a remaining amount storage means for storing the remaining amount of the remaining medicine determined to remain in the medicine container by the determination means, and a dispensing amount of the medicine based on the preparation data and the remaining amount. It is conceivable to include a deficient amount display means for displaying the amount of the drug deficient or the number of the drug containers based on the remaining amount of the remaining drug stored in the amount storage means. Accordingly, since the user can easily grasp whether or not the drug container needs to be loaded when using the remaining drug, and the number of the drug containers, the drug container is insufficient when using the remaining drug. You don't have to think about the number of yourself.
  • the mixed injection management device returns a predetermined return of the unused medicine container among the medicine containers loaded according to the amount of medicine dispensed based on the preparation data after the remaining medicine is used. It is conceivable to provide return processing means for returning from the mouth. As a result, since the surplus drug containers are automatically returned, the user is always required according to the preparation data without being aware of the number of drug containers to be loaded when using the remaining drug. The normal operation of determining and loading the number of drug containers can be performed.
  • the display control means displays only the preparation data including the same type of drug as the remaining drug as the prescription drug. It can also be displayed on the means. As a result, the user can easily confirm only the preparation data in which the remaining drug can be used.
  • the display control means preferentially displays preparation data including a mixed drug having the same component and mixing ratio as the prescription drug. It is possible to make it. Thereby, when the said remaining medicine arises also about the said mixing medicine, it becomes possible to support the efficient use which does not waste the remaining medicine.
  • the co-infusion apparatus includes the determination unit and the display control unit. Whether the drug remains in the drug container used in the mixed injection process in which the drug indicated in the preparation data is injected from one or a plurality of drug containers containing the predetermined amount of the drug into the infusion container. Judge whether or not.
  • the display control means uses, as a prescription drug, a medicine of the same type as the remaining medicine that has been determined to remain in the medicine container by the determination means in the past mixed injection process among the selection candidates of the preparation data to be subjected to the mixed injection process
  • the prepared preparation data is preferentially displayed on the display means.
  • the mixed injection processing unit holds the medicine container and can transport the medicine container to an arbitrary position, and holds the syringe and the medicine from the medicine container by the syringe.
  • a second robot arm capable of performing suction of the liquid and injection of the medicine into the infusion container.
  • the mixed injection management device moves the drug container determined by the determination means to retain the remaining drug to a standby position set in advance by the first robot arm, and moves the drug container to the first The robot arm can be taken out from the standby position.
  • the present invention may be understood as a mixed injection management program for causing a computer to function as each of the above means. That is, the mixed injection management program according to the present invention is used in the mixed injection process in which the drug indicated in the preparation data is injected into the infusion container from one or a plurality of drug containers in which a predetermined amount of the drug is stored in the computer.
  • This is a program for executing a display control step for preferentially displaying on the display means preparation data including a prescription drug containing the same type of drug as the remaining drug.
  • the mixed injection management program causes the computer to perform the mixed injection processing when the preparation data including the same type of drug as the remaining drug in the prescription drug is selected as the target of the mixed injection processing and satisfies a preset use condition. It is conceivable that this is a program for further executing the remaining medicine using step of using the remaining medicine.
  • the mixed injection management apparatus, mixed injection apparatus, and mixed injection management program which can support the efficient use of the chemical
  • the perspective view of the state which opened the main door of the mixed injection apparatus of FIG. The front view of the state which removed the main door and some front walls of the mixed injection apparatus of FIG.
  • the perspective view which shows the container used with the mixed injection apparatus of FIG. The perspective view which looked at the mixed injection apparatus of FIG. 4 from the downward direction.
  • the perspective view which shows the syringe operation part of the 2nd robot arm of the mixed injection apparatus of FIG. The plane schematic diagram which shows the container conveyance part of the mixed injection apparatus of FIG.
  • the perspective view which shows the mechanism with which the container conveyance part of the mixed injection apparatus of FIG. 2 is provided.
  • the perspective view which shows the ampoule cutter of the mixed injection apparatus of FIG. The perspective view which shows the internal structure of the stirring apparatus of the mixed injection apparatus of FIG.
  • the perspective view which shows the internal structure of the injection needle attaching / detaching apparatus of the mixed injection apparatus of FIG.
  • the flowchart which shows an example of the procedure of the mixed injection management process performed by the mixed injection management apparatus of FIG.
  • the flowchart which shows an example of the procedure of the mixed injection control process performed by the mixed injection management apparatus of FIG.
  • the figure for demonstrating the operation example of the mixed injection management apparatus of FIG. The figure for demonstrating the operation example of the mixed injection management apparatus of FIG.
  • the co-infusion device 1 As shown in FIG. 1, the co-infusion device 1 according to this embodiment includes a co-infusion management device 100, a medicine loading unit 200, and a co-infusion processing unit 300.
  • the co-infusion management unit 100 controls the operation of the co-infusion processing unit 300 so that a predetermined amount of the anti-cancer drug or the like indicated in the preparation data is stored.
  • a co-infusion process for injecting from one or more drug containers into the infusion container is executed.
  • the mixed injection management device 100 includes a first control unit 400 and a second control unit 500 that are connected to be capable of bidirectional communication via a communication network such as a LAN or the Internet.
  • the first control unit 400 is provided on the medicine loading unit 200 side, and the second control unit 500 is provided on the mixed injection processing unit 300 side.
  • the first control unit 400 is connected to a host system 600 such as an electronic medical record system or a dispensing management system that inputs preparation data to the co-infusion apparatus 1 via a communication network such as a LAN or the Internet.
  • the preparation data is preparation data generated based on the prescription data or the prescription data itself.
  • the prescription data includes prescription delivery date, patient ID, patient name, patient birth date, drug information (drug code, drug name, dose, etc.), dosage form information (internal use, external use, etc.), usage information (After three meals a day, etc.), medical treatment type (outpatient, hospitalization, etc.), medical department, ward, hospital room, etc. are included.
  • the preparation data includes patient information, doctor information, drug information, the amount of drug dispensed, the type of drug container (such as an ampoule with drug solution or a vial with powder), and preparation content information (drug container used for mixed injection processing, Syringe, type and number of needles, etc.) and preparation procedure information (dissolution source / destination drug, work content, volume / dissolution amount, sampling amount), preparation date, prescription classification, medication date, department, ward, preparation Time etc. are included.
  • the first control unit 400 is a personal computer including a CPU 401, a ROM 402, a RAM 403, a data storage unit 404, an operation unit 405, and the like.
  • Various electrical components such as a display 203, a barcode reader 204, and an air cleaning device 205 described later provided in the medicine loading unit 200 are connected to the first control unit 400.
  • the CPU 401 is a processor that executes processing according to various control programs.
  • the ROM 402 is a non-volatile memory in which programs such as BIOS executed by the CPU 401 are stored in advance.
  • the RAM 403 is a volatile memory or a non-volatile memory used for development of various control programs and temporary storage of data by the CPU 401.
  • the data storage unit 404 is a hard disk or the like that stores various application programs executed by the CPU 401 and various data. Specifically, the preparation data input from the host system 600 is stored in the data storage unit 404.
  • the data storage unit 404 stores various databases such as a pharmaceutical master, a patient master, a doctor master, a prescription category master, a clinical department master, and a ward master.
  • the medicine master includes medicine code, medicine name, JAN code (or RSS), medicine bottle code, classification (dosage form: powder, tablet, liquid medicine, topical medicine, etc.), specific gravity, kind of medicine (ordinary medicine, Anticancer drugs, poisons, narcotics, powerful drugs, antipsychotics, therapeutic drugs, etc.), formulation changes, excipients, precautions, types of drug containers (ampoules, vials), drug capacity per drug container ( Information such as a predetermined amount) and an empty weight for each medicine container.
  • the data storage unit 404 in which predetermined amount information indicating the amount (predetermined amount) of medicine stored in units of medicine containers corresponding to each type of medicine is stored is an example of the predetermined amount information storage unit.
  • the pharmaceutical master when there are a plurality of kinds of medicine containers for the same medicine, a predetermined amount corresponding to each medicine container is stored.
  • the data storage unit 404 stores in advance a mixed injection management program for causing the CPU 401 to execute a mixed injection management process (see FIG. 19) described later.
  • the mixed injection management program may be read from a recording medium such as a CD, a DVD, a BD, or a flash memory and installed in the data storage unit 404 by a reading device (not shown) provided in the first control unit 400.
  • the present invention may be understood as an invention of the mixed injection management program for causing the CPU 401 to execute the mixed injection management process or a computer-readable recording medium recording the mixed injection management program. Further, the present invention may be understood as an invention of a mixed injection management method for executing each processing procedure of the mixed injection management process in the mixed injection device 1.
  • the operation unit 405 includes various operation means such as a keyboard, a mouse, or a touch panel that receives various user operations in the first control unit 400.
  • the second control unit 500 is a personal computer including a CPU 501, a ROM 502, a RAM 503, a data storage unit 504, an operation unit 505, and the like.
  • the second control unit 500 is connected to various electrical components such as a robot arm 21, a robot arm 22, and a container transfer unit 110 described later provided in the mixed injection processing unit 300.
  • the CPU 501 is a processor that executes processing according to various control programs.
  • the ROM 502 is a non-volatile memory in which programs such as BIOS executed by the CPU 501 are stored in advance.
  • the RAM 503 is a volatile memory or a non-volatile memory used for development of various control programs by the CPU 501 and temporary storage of data.
  • the data storage unit 504 is a hard disk or the like that stores various application programs executed by the CPU 501 and various data.
  • the data storage unit 504 stores in advance a mixed injection control program for causing the CPU 501 to execute a mixed injection control process (see FIG. 21) described later.
  • the mixed injection control program may be read from a recording medium such as a CD, a DVD, a BD, or a flash memory and installed in the data storage unit 504 by a reading device (not shown) included in the second control unit 500. Good.
  • the operation unit 505 includes various operation means such as a keyboard, a mouse, or a touch panel that receives various user operations in the second control unit 500.
  • the medicine loading unit 200 is a clean bench including a door 201, a work table 202, a display 203, a barcode reader 204, and an air cleaning device 205. As shown in FIG. 3, the medicine loading unit 200 and the mixed injection processing unit 300 are communicated with each other through an opening 114 formed on a side surface of the mixed injection processing unit 300.
  • the display 203 is a display unit such as a liquid crystal display or an organic EL display that displays various types of information in accordance with control instructions from the first control unit 400. Specifically, the display 203 displays preparation data and the like that are candidates for co-infusion in the co-infusion apparatus 1. Further, the barcode reader 204 reads a barcode described in a prescription or a preparation instruction, and inputs the content of the barcode to the first control unit 400. The air cleaning device 205 supplies air into the medicine loading unit 200 through a predetermined filter.
  • the door 201 is provided in front of the medicine loading unit 200 and can be opened and closed in the vertical direction. As shown in FIG. 2, the user performs a preparatory work for the mixed injection process executed by the mixed injection device 1 in a state where the door 201 is slightly opened and a hand is placed in the medicine loading unit 200.
  • the container 101 placed on the work table 202 includes a drug container 10, a syringe 11, and an infusion bag used in the mixed injection process performed by the mixed injection device 1. 12 (an example of an infusion container) is accommodated.
  • the preparation operation includes, for example, a loading operation in which the drug container 10, the syringe 11, and the infusion bag 12 are placed at predetermined positions of the container 101, and the container 101 is loaded into the mixed injection processing unit 300. It is.
  • the drug container 10 is an ampoule
  • the drug container 10 is referred to as an ampoule 10A
  • the drug container 10 is referred to as a vial 10B.
  • the container 101 includes an electronic paper tag 101a on which a patient name and application are displayed in characters, and an IC tag (for example, RFID: Radio Frequency Identification) (not shown) that can read and write various types of information.
  • the first control unit 400 reads information recorded on the IC tag (not shown) by a reading unit (not shown), and recognizes the content of the mixed injection process to be started based on the information.
  • the first control unit 400 reads the preparation data specified by the information read from the IC tag from a storage unit such as the data storage unit 404. In this case, the first control unit 400 can collate the medicine loaded in the container 101 with the preparation data to be subjected to the mixed injection process.
  • the container 101 has a drug placement section 102 (see FIGS. 10 and 11) on which the medicine container 10 and the syringe 11 are placed, and an infusion bag holding section 103 (see FIG. 10) for holding the infusion bag 12. 5).
  • the medicine placement unit 102 and the infusion bag holding unit 103 can be individually attached to and detached from the container 101.
  • the medicine mounting portion 102 is provided with a support portion 102 ⁇ / b> A that supports the ampoule 10 ⁇ / b> A in an inclined state.
  • the ampoule 10A is set in a state where the ampoule 10A is stood diagonally by the support portion 102A. Thereby, a medicine does not accumulate on the neck of the ampoule 10A.
  • the injection needle of the syringe 11 is set in a state where it is stood obliquely on the support portion 102A.
  • the vial bottle 10B and the syringe 11 are set in a state in which they are laid down on the drug placement section 102. At this time, the syringe 11 is in a state of only a syringe without an injection needle.
  • positioning form in the said medicine mounting part 102 demonstrated here is an illustration, and is not limited to this.
  • the infusion bag holding portion 103 is provided with a chuck portion 140 for fixing the mixed injection port (neck portion) of the infusion bag 12.
  • the user sets the infusion bag 12 in the infusion bag holding portion 103 in a state where the infusion bag 12 is held by the chuck portion 140.
  • the infusion bag holding portion 103 is provided with an engagement hole portion 103a used when the infusion bag holding portion 103 is raised and lowered.
  • the container 101 is supplied to the mixed injection processing unit 300 through the opening 114 after the drug container 10, the syringe 11, and the infusion bag 12 are set by a user. It is also conceivable that the medicine loading unit 200 includes a loading mechanism such as a belt conveyor that automatically loads the container 101 into the mixed injection processing unit 300.
  • a main door 301, a syringe take-out door 302, a garbage storage room door 13, a touch panel monitor 14, and a container discharge door 15 are provided on the front surface of the mixed injection processing unit 300. .
  • the main door 301 is opened and closed to access the mixed injection processing chamber 104 when, for example, cleaning the mixed injection processing chamber 104 provided in the mixed injection processing unit 300.
  • poured out it is also possible to pay out the said syringe 11 in the state with which the chemical
  • the syringe outlet door 302 is opened and closed when the syringe 11 is taken out from the mixed injection processing chamber 104.
  • the waste storage chamber door 13 is for removing the waste from the waste storage chamber 13a in which waste such as the medicine container 10 and the syringe 11 after being used in the mixed injection processing in the mixed injection processing chamber 104 is stored. Is opened and closed. Further, the container discharge door 15 is opened and closed to take out the container 101 on which the infusion bag 12 is placed after the medicine is mixedly injected by the mixed injection processing in the mixed injection processing chamber 104.
  • the touch panel monitor 14 is a display unit such as a liquid crystal display or an organic EL display that displays various types of information in response to a control instruction from the second control unit 500.
  • the touch panel monitor 14 can display, for example, an image or video captured by various cameras described later.
  • FIGS. 3 and 4 As shown in FIGS. 3 and 4, in the mixed injection processing chamber 104, a first robot arm 21, a second robot arm 22, an ampoule cutter 31, an agitator 32, and a mounting device having an articulated structure are placed. A shelf 33, a medicine reading unit 34, a weighing meter 35, a needle bending detection unit 36, a mixed injection communication port 37, a needle insertion confirmation transparent window 38, a dust cover 132a, and the like are provided. Further, as shown in FIG.
  • a tray confirmation camera 41, a syringe confirmation camera 42, a syringe needle attachment / detachment device 43, a needle insertion confirmation camera 44, a sterilization lamp 45, and the like are provided on the ceiling side of the mixed injection processing chamber 104.
  • the first robot arm 21 and the second robot arm 22 are provided in a hanging manner with their base ends fixed to the ceiling side of the mixed injection processing chamber 104. Yes.
  • the indirect of the first robot arm 21 and the second robot arm 22 is about 5 to 8 axes, respectively.
  • each work process in the mixed injection process is executed by the double-armed robot arms 21 and 22.
  • the second control unit 500 individually drives the drive motors provided indirectly to the first robot arm 21 and the second robot arm 22, so that the first robot arm 21 and the second robot arm 22 are driven.
  • the robot arm 22 is caused to execute each operation in the mixed injection process.
  • the mixed injection processing unit 300 has, for example, a configuration including one robot arm, a configuration including three or more robot arms, or a configuration not using a robot arm as long as the mixed injection processing unit 300 can execute the mixed injection processing. It may be.
  • the first robot arm 21 includes a container holding unit 25 that holds the drug container 10, and the second robot arm 22 holds the syringe 11, A syringe operation unit 26 for performing suction and injection is provided.
  • the container holding portion 25 of the first robot arm 21 includes a pair of gripping claws 25a, a motor 251, two screw shafts 252 and 253 rotated by the motor 251, and the screw shaft.
  • Nut blocks 254 and 255 screwed to 252 and 253 are provided.
  • the pair of gripping claws 25a are fixed to the nut blocks 254 and 255, respectively. Then, the nut blocks 254 and 255 move by the rotation of the screw shafts 252 and 253, and the pair of gripping claws 25a approach and separate from each other to hold and release the container holding part 25.
  • the pair of gripping claws 25a have a recess suitable for holding the vial 10B, and a recess suitable for holding the ampoule 10A on the tip side.
  • FIG. 7 shows a state in which both the ampoule 10A and the vial bottle 10B are held, but in reality, one ampoule 10A or the vial bottle 10B is held.
  • the container holding part 25 can also hold the injection needle with a cap or the syringe 11 by the pair of gripping claws 25a.
  • the second control unit 500 measures the diameter of the syringe 11 according to the driving amount of the motor 251 when the syringe 11 is held by the pair of gripping claws 25a of the container holding unit 25. Is possible. Accordingly, the second controller 500 can determine whether the syringe 11 is a syringe designated by the preparation content information of the preparation data.
  • the syringe operation unit 26 of the second robot arm 22 includes a syringe holding unit 261, a plunger holding unit 262, and a moving unit 263.
  • the syringe holding unit 261 includes a pair of gripping claws 261 a that hold the syringe body 11 a of the syringe 11.
  • the pair of gripping claws 261a hold and release the syringe main body 11a of the syringe 11 by approaching and separating from each other by a mechanism similar to the drive mechanism used in the container holding unit 25.
  • inclined portions 261b that are inclined downward from the gripping claw upper end surface toward the facing surface are formed on opposing surfaces facing each other.
  • the plunger holding portion 262 includes a pair of gripping claws 262 a that hold the collar portion of the plunger 11 b of the syringe 11.
  • the pair of gripping claws 262a hold and release the buttocks of the plunger 11b of the syringe 11 by approaching and separating from each other by a mechanism similar to the drive mechanism used in the container holding unit 25.
  • a gripping claw 262b is fixed to the upper surface of each gripping claw 262a.
  • the pair of gripping claws 262a also approaches and separates, and not only the syringe 11 but also other articles such as the drug container 10 can be gripped.
  • the recessed part for the collar part of the said plunger 11b to enter is formed in the upper surface of the opposing side of said pair of holding claw 262a. Further, the tips of the pair of gripping claws 262b protrude forward from the pair of gripping claws 262a, and the pair of gripping claws 262b can easily grip articles such as the ampoule 10A and the vial bottle 10B.
  • the grip claw 262b may be provided on the grip claw 261a.
  • the moving part 263 can move the plunger holding part 262 in the moving direction of the plunger 11 b of the syringe 11.
  • the moving unit 263 moves the plunger 11b by a driving mechanism such as a motor, a screw shaft rotated by the motor, a nut block screwed to the screw shaft, and a guide.
  • the plunger holding part 262 is fixed to the nut block, and moves by the movement of the nut block.
  • the mixed injection processing unit 300 transports the container 101 supplied from the communication opening 114 at the right end portion in FIG. 6 to the container transport end portion 110a at the left end portion.
  • a section 110 is provided.
  • FIG. 10 is a schematic plan view showing an example of the transport path of the container 101 in the container transport unit 110.
  • the inside of the container transport unit 110 is set to a positive pressure than the inside of the mixed injection processing chamber 104.
  • the container transport unit 110 allows the container 101 to pass through the rear side of the dust storage chamber 13a located below the mixed injection processing chamber 104 and below the dust cover 132a. It is provided to convey. Thereby, the said garbage storage chamber 13a can be accessed from the front side of the said co-infusion apparatus 1.
  • FIG. 10 in order to show the transport route of the container transport unit 110, the container 101 that moves in the container transport unit 110 is indicated by a two-dot chain line, and a plurality of the containers are simultaneously included in the container transport unit 110. 101 does not exist.
  • the second control unit 500 determines that the container 101 has reached a predetermined position in the container transport unit 110 through the communication opening 114 based on, for example, an output of a sensor, the second control unit 500 and the container transport unit 110 and A shutter 111 for communicating and shielding the mixed injection processing chamber 104 is slid in the horizontal direction.
  • the shutter 111 is opened, the medicine placement unit 102 is exposed in the mixed injection processing chamber 104.
  • FIG. 10 shows a state in which the medicine placement unit 102 is exposed in the mixed injection processing chamber 104.
  • the container transport unit 110 has a tray lifting / lowering mechanism that lifts and lowers the drug placement unit 102 in the container 101 moved into the container transport unit 110 through the communication opening 114.
  • a portion 112 is provided.
  • the tray lifting / lowering unit 12 lifts the drug placement unit 102 from the bottom to the top by driving the four shafts 112a provided in a vertically movable manner, for example.
  • the second control unit 500 raises the medicine placing unit 102 by the tray lifting / lowering unit 112, and then performs imaging by the tray confirmation camera 41.
  • the tray confirmation camera 41 images the medicine container 10 and the syringe 11 on the medicine placement unit 102.
  • the second control unit 500 executes image recognition processing using an image captured by the tray confirmation camera 41, and the number of the medicine containers 10 and the syringes 11 indicated by the preparation data are placed on the medicine placement. It is determined whether or not it exists on the unit 102.
  • terminus part 110a is provided with the bag raising / lowering part 113 which raises / lowers the said infusion bag holding
  • the second control unit 500 transports the container 101 to the front of the bag lifting / lowering unit 113, and then hooks the hook 113a of the bag lifting / lowering unit 113 into the engagement hole 103a from below. Then, the second control unit 500 drives the arc gear portion 113b formed with the hook portion 113a to rotate by a motor 113c, thereby raising the infusion bag holding portion 103 and opening the mixed injection port of the infusion bag 12. It is located in the mixed injection communication port 37. In addition, the second control unit 500 controls the motor 113c to drive the bag elevating unit 113 to incline the infusion bag holding unit 103 so that the mixed injection port of the infusion bag 12 faces upward or downward. can do.
  • the ampoule cutter 31 is provided with a file portion 31a, a waste tray 31b, a head insertion portion 31c, a drive box 31f, a waste box 31g, and a gripping portion 31h. .
  • the file portion 31a is a member for notching the neck of the ampoule 10A, and the waste generated by the notch processing in the file portion 31a falls on the waste tray 31b.
  • the first robot arm 21 holds the ampule 10A and slides with the neck of the drug container 10 in contact with the file portion 31a, thereby causing the neck of the ampule 10A to slide. Is notched.
  • the head insertion portion 31c includes a hole 31d into which the head of the medicine container 10 subjected to the notch processing is inserted from below, and a side of the head of the medicine container 10 protruding upward from the hole 31d. And a pusher 31e positioned at the same position.
  • the drive box 31f has a cam provided therein and a drive motor for driving the cam. When the cam is driven by the drive motor, the pusher 31e is moved by the cam to the drug container. 10 reciprocates in the direction of approaching and separating from the head.
  • the first robot arm 21 holds the ampoule 10A by the gripping claws 25a, the head of the medicine container 10 is inserted into the hole 31d from below, and the head above the neck is Project upward. Thereafter, when the drive motor of the drive box 31f is driven by the second controller 500 and the pusher 31e is moved in a direction of pushing the head of the medicine container 10, the pusher 31e causes the head to move. It is pushed and broken. At this time, the head folded by the pusher 31e falls into the waste box 31g.
  • the grip portion 31h is used by a user when the ampule cutter 31 is slid along a rail 31i (see FIG. 4) that slidably supports the ampule cutter 31.
  • the agitator 32 when a powder is stored in the vial 10B, injects an infusion or a drug into the vial 10B, dissolves the powder, and generates a mixed drug. Used when.
  • the stirring device 32 includes two rollers 32a, a pressing portion 32b, a rotation support portion 32c, a support base 32d, a horizontal swing mechanism 32e, a support portion 32f, and a drive motor. 32g etc. are provided.
  • the two rollers 32a are opposed to each other with a predetermined distance therebetween.
  • One roller 32a is rotatably supported, and the other roller 32a is connected to the drive motor 32g.
  • Each of the rollers 32a is elongated in the axial direction, and the stirring device 32 can simultaneously stir the two vial bottles 10B placed on both ends of the roller 32a in the axial direction. .
  • the presser 32b is a driven roller that is used to press the vial 10B placed on the roller 32a from above and rotates as the drug container 10 rotates.
  • the rotation support part 32 c rotates the pressing part 32 b in a direction in which the pressing part 32 b comes into contact with or separates from the drug container 10 by a drive motor (not shown).
  • the support base 32d supports the roller 32a, the pressing portion 32b, the rotation support portion 32c, and the like.
  • the horizontal swing mechanism 32e has a crank mechanism, for example, and can swing the support base 32d in the axial direction of the roller 32a.
  • the support portion 32f has U-shaped notches into which the neck of the vial bottle 10B is fitted at both ends in the axial direction of the roller 32a.
  • the neck of the drug container 10 is engaged with the notch.
  • the support base 32d is swung in the axial direction of the roller 32a by the horizontal swing mechanism 32e, the drug container 10 swings following the swing of the roller 32a in the axial direction.
  • the medicine in the medicine container 10 is stirred in the horizontal direction.
  • the mounting shelf 33 is used for temporarily placing the medicine container 10, the syringe 11 and the like in the mixed injection process executed in the mixed injection device 1. Further, the placement shelf 33 is also used as a standby position for waiting the medicine container 10 when the medicine remains in the medicine container 10 after the mixed injection process is executed. Of course, the standby position may be provided at a position different from the placement shelf 33 described above.
  • the placement shelf 33 is provided at a position accessible by both the first robot arm 21 and the second robot arm 22.
  • the vial bottle 10B is placed in a state where it is stood at a predetermined position.
  • the placement shelf 33 is provided with an inclination holding part for holding the ampoule 10A in an inclined state, and the ampoule 10A is placed in an inclined state on the inclination holding part.
  • the mounting shelf 33 is formed with a neck holding hole having a predetermined diameter in which the neck portion of the syringe 11 is fitted, and the syringe 11 is in a state of only a syringe to which no injection needle is attached. Temporarily placed with the neck facing down.
  • the drug reading unit 34 reads a barcode indicating information on the contained medicine described on a label affixed to the drug container 10 such as the ampoule 10A and the vial bottle 10B. It is. Specifically, the medicine reading unit 34 includes two rollers 34a and a barcode reader 34b as shown in FIG. The rollers 34a are arranged to face each other with a predetermined interval. One of the rollers 34a is rotatably supported, and the other roller 34a is connected to a drive motor (not shown). The drug container 10 is placed between the two rollers 34a. When the roller 34a is rotated by the drive motor, the drug container 10 rotates.
  • the barcode reader 34b can read the barcode from the label of the medicine container 10 regardless of the orientation of the medicine container 10 when placed on the roller 34a.
  • the weighing meter 35 is used to measure the weight of the syringe 11 in the mixed injection process executed in the mixed injection device 1, and the measurement result by the weighing meter 35 is sent to the second control unit 500. Entered. Accordingly, the second control unit 500 calculates the difference between the weight of the syringe 11 after the drug is sucked from the drug container 10 and the known weight of the syringe 11 itself, for example, so that the drug container 10 It is possible to acquire the amount of the chemical liquid sucked from
  • the needle bend detecting section 36 is formed with a long hole 36a into which the injection needle 11c of the syringe 11 can be inserted and moved.
  • the needle bending detection unit 36 includes a first optical sensor 361 and a second optical sensor 362 that are arranged so that the light beams are irradiated and received with the elongated hole 36a interposed therebetween and the light beams are not parallel to each other. . Detection results from the first optical sensor 361 and the second optical sensor 362 are input to the second control unit 500.
  • the second robot arm 22 inserts the injection needle 11c attached to the syringe 11 into the elongated hole 36a and moves it up and down.
  • the second control unit 500 can detect the bending of the injection needle 11c using the position information of the injection needle 11c when blocking the light beam.
  • the injection needle 11c is imaged with a camera and the needle bending is detected by image recognition on the captured image.
  • the second control unit 500 controls the infusion bag 12 with the injection needle 11c by the second robot arm 22 based on the bending amount of the injection needle 11c. The needle tip position or direction when puncturing the mixed injection port is corrected.
  • a dome shape that illuminates the infusion bag 12 transported to the container transport terminal portion 110a above the container transport terminal portion 110a located in the left space of the mixed injection processing chamber 104.
  • a light 120 and a camera 121 are provided.
  • the camera 121 is provided at the center of the dome-shaped light 120 and reads a barcode attached to the surface of the infusion bag 12. Accordingly, the second control unit 500 can determine whether the infusion bag 12 is appropriate according to the barcode information read by the camera 121.
  • the mixed injection communication port 37 is formed in a dome-shaped portion protruding outward on the side wall of the mixed injection processing chamber 104, and the dome-shaped portion of the infusion bag 12 extends vertically. A notch for passing the mixed injection port is formed. Therefore, when the infusion bag holding part 103 is raised, the mixed injection port of the infusion bag 12 is located in the mixed injection processing chamber 104.
  • the syringe confirmation camera 42 is used to image the syringe 11 in order to confirm the presence and amount of the medicine sucked into the syringe 11.
  • the second control unit 500 causes the touch panel monitor 14 to display an image captured by the syringe confirmation camera 42, for example.
  • the captured image is stored in a storage unit such as a hard disk provided inside or outside the co-infusion apparatus 1 for final inspection, for example.
  • the injection needle attaching / detaching device 43 has the needle tip of the injection needle 11c with a cap facing upward in the hole 43b of the chuck portion 43a in which the cut portion is formed. Plugged in.
  • the hole 43b of the chuck portion 43a is expanded by a cam mechanism (not shown) so that the injection needle 11c with the cap can be inserted.
  • the driving of the motor 43c is stopped, the holding state of the capped injection needle 11c is maintained by the spring 43d.
  • the needle turning motor 43e When the needle turning motor 43e is driven, the gear 43f and the gear 43g are rotated, the chuck portion 43a is rotated, and the injection needle 11c with cap is rotated. Thereby, attachment and detachment and exchange of the injection needle 11c with the cap to the syringe 11 can be performed.
  • the ampoule 10A it is possible to automatically replace the frame type filter.
  • the needle tip of the injection needle 11c with the cap faces upward in the injection needle attaching / detaching device 43, the distal end opening of the syringe main body 11a from which the injection needle 11c is removed faces upward, and the syringe main body 11a Liquid dripping from the neck opening can be prevented.
  • the needle insertion confirmation camera 44 can fit the infusion bag 12 located outside the mixed injection processing chamber 104 and the syringe 11 in the mixed injection processing chamber 104 into one image. Take an image.
  • the second controller 500 images the direction of the needle insertion confirmation transparent window 38 with the needle insertion confirmation camera 44 when the injection port of the infusion bag 12 is punctured with the injection needle 11c.
  • An image captured by the needle insertion confirmation camera 44 is displayed on, for example, the touch panel monitor 14.
  • FIG. 18 is an example of an image captured by the needle insertion confirmation camera 44. Thereby, the user can confirm whether the front end side of the said injection needle 11c is located in the said infusion solution bag 12 with the said captured image.
  • the captured image is stored in a storage unit such as a hard disk provided inside or outside the co-infusion apparatus 1 for final inspection, for example.
  • a storage unit such as a hard disk provided inside or outside the co-infusion apparatus 1 for final inspection, for example.
  • the sterilization lamp 45 is turned on, for example, 3 hours before the start of the mixed injection process. As shown in FIG. 6, one of the two germicidal lamps 45 is provided at a position between the first robot arm 21 and the second robot arm 22. Therefore, the amount of sterilization light blocked by the first robot arm 21 and the second robot arm 22 is reduced, and the inside of the mixed injection processing chamber 14 can be sterilized uniformly. Further, the mixed injection processing unit 300 sucks air in the mixed injection processing chamber 104 from a slit 104b (see FIGS. 3 and 4) formed in a lower portion of the side wall of the mixed injection processing chamber 104, and the mixed injection processing chamber 300.
  • a slit 104b see FIGS. 3 and 4
  • An exhaust system for exhausting air from an exhaust fan (not shown) provided above 104 is provided.
  • an air supply system is also provided that cleans the outside air from an air inlet formed in the ceiling portion of the mixed injection processing chamber 104 and guides it to the mixed injection processing chamber 104 and the like.
  • the second control unit 500 opens the shutter 111 when the container 101 is supplied to the container transport unit 110. Then, the container transport section 110 raises the medicine placement section 102 of the container 101 by the tray lifting / lowering section 112 and exposes it to the mixed injection processing chamber 104.
  • the first robot arm 21 grasps the syringe 11 placed on the medicine placement section 102 exposed in the mixed injection processing chamber 104 and temporarily places it on the placement shelf 33.
  • the first robot arm 21 sets the ampoule 10 ⁇ / b> A placed on the medicine placing unit 102 on the medicine reading unit 34.
  • the medicine reading unit 34 reads information such as the type of medicine contained in the ampoule 10A.
  • the first injection needle 11 c is set on the injection needle attaching / detaching device 43, and the second injection needle 11 c is temporarily placed on the placement shelf 33.
  • a cap is attached to the injection needle 11 c placed on the medicine placement section 102, and the cap is attached and detached by the injection needle attaching / detaching device 43.
  • the second control unit 500 grasps the position and orientation of the ampoule 10A and the syringe 11 placed on the medicine placement unit 102 by the image recognition process for the captured image of the tray confirmation camera 41.
  • the second control section 500 takes an image of the medicine placement section 102 with the tray confirmation camera 41, and updates the latest from the captured image. The position and direction of the ampule 10A and the syringe 11 are grasped.
  • the second control unit 500 performs the image recognition process to determine whether or not all articles on the medicine placement unit 102 have been taken out.
  • the second control unit 500 is configured so that the ampule 10A, the syringe 11, and the injection needle 11c are mounted on the drug by the number of drugs, syringes, and needles indicated in the preparation content information of the preparation data. It may be determined based on an image captured by the tray check camera 41 whether or not the image is present in the placement unit 102. If it does not exist, the second controller 500 may display that fact on the touch panel monitor 14. Further, before the syringe 11 and the like in the medicine placement section 102 are taken out by the first robot arm 21, the medicine placement section 102 is photographed by the tray confirmation camera 41. Therefore, the ampule 10A, The shortage of the syringe 11 and the injection needle 11c can be notified early.
  • the container transport section 110 moves the medicine placement section 102 to the tray lifting / lowering section 112. Lower and return to the container 101.
  • the second control unit 500 closes the shutter 111 and causes the container transport unit 110 to transport the container 101 to the container transport end unit 110a.
  • the container transfer unit 110 uses the mixed injection port of the infusion bag 12 held by the infusion bag holding unit 103 of the container 101 as the mixed injection processing chamber. It is located in the mixed injection communication port 37 formed in 104.
  • the second robot arm 22 moves the ampule 10 ⁇ / b> A set in the medicine reading unit 34 to the mounting table 33.
  • the first robot arm 21 takes out the syringe 11 from the mounting table 33 and sets it on the second robot arm 22.
  • the second robot arm 22 moves the syringe 11 to the injection needle attaching / detaching device 43 to set the injection needle 11 c in the syringe 11.
  • the second robot arm 22 moves the syringe 11 to the needle bending detection unit 36 to detect the presence or absence of the bending of the injection needle 11c.
  • the first robot arm 21 takes out the ampoule 10A from the mounting table 33 and uses the ampoule cutter 31 to fold the head of the ampoule 10A. Then, the first robot arm 21 and the second robot arm 22 bring the ampule 10A and the syringe 11 close to each other and insert the injection needle 11c of the syringe 11 into the ampule 10A. Thereafter, the second robot arm 22 operates the plunger 11b to suck the mixed drug in the ampoule 10A with the syringe 11.
  • the first robot arm 21 and the second robot arm 22 gradually tilt the posture of the ampoule 10A and the syringe 11.
  • the ampoule 10A is A state in which the drug solution is moved to the mouth side (neck portion) is formed by inclining about 100 degrees with respect to the direction.
  • the tip of the injection needle 11c of the syringe 11 can be sucked up without leaving as much as possible without attaching the tip of the injection needle 11c to the bottom of the ampoule 10A.
  • the first robot arm 21 and the second robot arm 22 exchange the injection needle 11 c of the syringe 11.
  • the second robot arm 22 moves the syringe 11 to the injection needle attaching / detaching device 43 and attaches the cap to the injection needle 11c.
  • the first robot arm 21 removes the injection needle 11c from the syringe 11 by rotating the injection needle 11c while the syringe 11 is held by the second robot arm 22.
  • the second controller 500 opens the dust cover 132a, and the first robot arm 21 drops the injection needle 11c into the dust storage chamber 13a and discards it. Thereafter, the first robot arm 21 sets the replaced injection needle 11 c on the injection needle attaching / detaching device 43 from the mounting table 33.
  • the second robot arm 22 moves the syringe 11 to the injection needle attaching / detaching device 43 to attach the injection needle 11 c to the syringe 11.
  • the injection needle 11c is exchanged between when the drug is sucked from the ampule 10A and when the infusion is injected into the infusion bag 12, fragments of the ampule 10A are mixed into the infusion bag 12. It is prevented.
  • the second robot arm 22 punctures the injection needle 11c of the syringe 11 into the mixed injection port of the infusion bag 12 conveyed to the container conveyance terminal portion 110a, and mixes the drug in the syringe 11 with the mixture. Inject into the infusion bag 12.
  • the second controller 500 opens the dust cover 132a, and the first robot arm 21 drops the ampoule 10A into the dust storage chamber 13a and discards it.
  • the second robot arm 22 moves the syringe 11 to the syringe needle attaching / detaching device 43 to attach the cap to the syringe needle 11c of the syringe 11, and then moves the syringe 11 to the dust storage chamber. Drop into 13a and discard.
  • the second control unit 500 opens the shutter 111 when the container 101 is supplied to the container transport unit 110. Then, the container transport section 110 raises the medicine placement section 102 of the container 101 by the tray lifting / lowering section 112 and exposes it to the mixed injection processing chamber 104.
  • the first robot arm 21 grasps the syringe 11 placed on the medicine placement section 102 exposed in the mixed injection processing chamber 104 and temporarily places it on the placement shelf 33.
  • the first robot arm 21 sets the vial 10 ⁇ / b> B placed on the medicine placing unit 102 on the medicine reading unit 34.
  • the medicine reading unit 34 reads information such as the type of medicine stored in the vial bottle 10B.
  • the container transport section 110 moves the medicine placement section 102 to the tray lifting / lowering section 112.
  • the second control unit 500 closes the shutter 111 and causes the container transport unit 110 to transport the container 101 to the container transport end unit 110a.
  • the container transfer unit 110 uses the mixed injection port of the infusion bag 12 held by the infusion bag holding unit 103 of the container 101 as the mixed injection processing chamber. It is located at the mixed injection communication port 37 formed at 104.
  • the second robot arm 22 moves the vial 10 ⁇ / b> B set in the medicine reading unit 34 to the mounting table 33.
  • the first robot arm 21 sets the injection needle 11 c of the syringe 11 placed on the medicine placement unit 102 to the injection needle attaching / detaching device 43.
  • the first robot arm 21 takes out the syringe 11 from the mounting table 33 and sets it on the second robot arm 22.
  • the second robot arm 22 moves the syringe 11 to the syringe needle attaching / detaching device 43 to set the syringe needle 11 c in the syringe 11.
  • the second robot arm 22 moves the syringe 11 to the needle bending detection unit 36 to detect the presence or absence of the bending of the injection needle 11c.
  • the second robot arm 22 punctures the injection needle 11c of the syringe 11 into the co-infusion port of the infusion bag 12 transported to the container transport terminal portion 110a, and the preparation data from the infusion bag 12 Aspirate the infusion of the indicated volume.
  • the first robot arm 21 takes out the vial 10 ⁇ / b> B placed on the placing table 33.
  • the first robot arm 21 and the second robot arm 22 bring the vial bottle 10B and the syringe 11 close to each other and puncture the vial bottle 10B with the injection needle 11c of the syringe 11.
  • the second robot arm 22 injects the infusion solution in the syringe 11 into the vial bottle 10B by operating the plunger 11b.
  • a mixed medicine is produced in the vial bottle 10B.
  • the posture of the syringe 11 and the vial bottle 10B is such that the injection needle 11c of the syringe 11 is directed vertically downward, and the mouth of the vial bottle 10B is directed vertically upward.
  • the first robot arm 22 sets the vial bottle 10 ⁇ / b> B into which the infusion solution has been injected into the stirring device 32.
  • medical agent and infusion in the said vial bottle 10B are stirred.
  • the first robot arm 21 takes out the vial 10B from the stirring device 32.
  • the first robot arm 21 and the robot arm 22 bring the vial bottle 10B and the syringe 11 close to each other, and puncture the vial bottle 10B with the injection needle 11c of the syringe 11.
  • the second robot arm 22 operates the plunger 11b to suck the mixed drug in the vial bottle 10B with the syringe 11.
  • the postures of the syringe 11 and the vial bottle 10B are such that the vial bottle 10B has the mouth portion directed vertically downward and the injection needle 11c of the syringe 11 directed vertically upward.
  • the second robot arm 22 punctures the injection needle 11c of the syringe 11 into the mixed injection port of the infusion bag 12 conveyed to the container conveyance terminal portion 110a, and mixes the drug in the syringe 11 with the mixture. Inject into the infusion bag 12. Meanwhile, the second controller 500 opens the dust lid 132a, and the first robot arm 21 drops the vial 10B into the dust storage chamber 13a and discards it. The second robot arm 22 sets the syringe 11 on the syringe needle attachment / detachment device 43, attaches the cap to the syringe needle 11c of the syringe 11, and then moves the syringe 11 to the dust storage chamber. Drop into 13a and discard.
  • the mixed injection process when injecting the drug solution stored in the vial bottle 10B into the infusion bag 12 generates a mixed drug that sucks the infusion solution from the infusion bag 12 and injects it into the vial bottle 10B to be stirred. This is the same as the co-infusion process when injecting the powder contained in the vial bottle 10B into the infusion bag 12 except that the process for performing is not executed.
  • steps S11, S12, S13... Shown in FIG. 19 are steps of the mixed injection management process executed by the first control unit 400, and steps S21, S22, S23.
  • symbol of the procedure of the said mixed injection control process which the 2nd control part 500 performs is shown.
  • each processing procedure of the mixed injection management process and the mixed injection control process is the same as that of the first control unit 400 and It may be executed by one of the second control units 500.
  • the mixed injection management apparatus 100 includes one control unit or three or more control units, and the mixed injection management process and the mixed injection control process are executed by the control unit as another embodiment. .
  • part or all of the processing executed by the first control unit 400 and the second control unit 500 may be executed by an electronic circuit such as an ASIC or DSP.
  • step S11 the first control unit 400 determines whether or not the preparation data has been input.
  • the preparation data is input when the preparation data is received from the host system 600 or when the barcode indicating the preparation data is read by the barcode reader 204.
  • step S11 if the said 1st control part 400 judges that the said preparation data was input (Yes side of S11), it will transfer a process to step S12, and if the said preparation data is not input (No side of S11) Then, the process proceeds to step S13.
  • step S12 the first controller 400 generates a prescription selection screen M1 in which selection candidates for the preparation data to be subjected to the mixed injection process in the mixed injection device 1 are arranged, and the display 203 Display.
  • the preparation data of the selection candidates are arranged according to the preset sorting conditions on the prescription selection screen M1. Displayed with status.
  • the sort condition is determined, for example, by any one or a combination of a preparation date / time, a medication date / time, a prescription category, and a preparation data issue date / time by the mixed injection device 1.
  • the user refers to the prescription selection screen M1 and puts the number of the drug containers 10 and the syringes 11 necessary for the preparation data displayed on the top of the prescription selection screen M1 in the mixed injection device 1 into the container 101.
  • the container 101 is loaded into the mixed injection processing unit 300.
  • FIG. 20 is a diagram showing an example of the prescription selection screen M1.
  • a search condition display unit D1 in which an input field of search conditions for narrowing down the selection candidates is arranged, and a prescription display unit in which the preparation data of the selection candidates are arranged side by side D2 and the like are included.
  • an extraction key D11 for starting an extraction process for narrowing down selection candidates for the preparation data according to the search conditions is arranged.
  • the prescription display unit D2 indicates whether or not the prescription drug includes preparation data that includes a prescription drug containing the same type of drug as the residual drug remaining in the drug container 10 in the mixed injection process that has been performed in the past.
  • Presence / absence display portion D21 is arranged. That is, the remaining drug presence / absence display unit D21 indicates whether or not the data is preparation data that can execute the mixed injection process using the remaining drug.
  • information such as characters, symbols, figures, or illustrations indicates whether or not the remaining drug is preparation data that can be used.
  • the first control unit 400 can change ON / OFF of the remaining medicine use function for using the remaining medicine generated in the past mixed injection process in the next mixed injection process according to the user operation in the initial setting or the like. It is. Thereby, the user can arbitrarily switch whether to receive support for using the remaining medicine in the next mixed injection process.
  • the first control unit 400 may be configured to be able to switch on / off the remaining medicine use function in accordance with a user operation on the prescription selection screen M1.
  • the first control unit 400 executes processing after step S16 described later when the remaining medicine use function is ON, and after step S16 described later when the remaining medicine use function is OFF. It is conceivable that the above process is not executed. Further, when the remaining medicine use function is OFF, the first control section 400 may hide the remaining medicine presence / absence display section D21 on the prescription selection screen M1.
  • the first control unit 400 has a sort condition setting function for setting the sort condition in accordance with a user operation on the operation unit 405 in an initial setting or the like.
  • the first control unit 400 can change the display order of the preparation data by changing the sort condition also on the prescription selection screen M1. That is, the first control unit 400, when the display location of each display item of the prescription display unit D2 is operated by the mouse or the touch panel of the operation unit 405, ascending order or descending order for the operated display item. It is possible to rearrange the preparation data so that
  • step S13 the first control unit 400 determines whether or not an extraction start operation for extracting specific preparation data from the preparation data of selection candidates has been performed. Specifically, the first control unit 400 performs the extraction according to whether the search condition is set in the search condition display unit D1 and the extraction key D11 is operated by a user operation on the operation unit 405. Determine whether there is a start operation.
  • step S131 when the first control unit 400 determines that the extraction start operation has been performed (Yes side of S13), the process proceeds to step S131, and if the extraction start operation has not been performed (No side of S13). Then, the process proceeds to step S14.
  • step S131 the first control unit 400 extracts the preparation data as selection candidates according to the search condition.
  • the prescription selection screen M1 shown in FIG. 20 shows that the result of the extraction of the preparation data is performed by inputting “2012/07/12” in the dispensing date input field indicating the scheduled execution date of the mixed injection process. It is a displayed example.
  • step S132 the first controller 400 displays the prescription selection screen M1 on which the preparation data extracted in step S131 is arranged, and returns the process to step S11.
  • the prescription selection screen M1 shown in FIG. 20 displays a plurality of the preparation data extracted in the step S131 when it is set in advance that the medication dates are arranged and displayed from the top in order from the earliest. It is an example.
  • step S14 the first control unit 400 determines whether or not a user operation for selecting any of the preparation data has been performed on the operation unit 405.
  • the process proceeds to step S15 until the preparation data selection operation is performed. (No side of S14) shifts the process to step S11.
  • step S15 the first control unit 400 transmits the preparation data selected by the selection operation in step S14 to the second control unit 500.
  • the first control unit 400 generates not only the preparation data itself but also the mixed injection control data for causing the mixed injection processing unit 300 to execute the mixed injection processing based on the preparation data, and the mixed injection control data is used as the mixed injection control data. It may be transmitted to the second control unit 500.
  • Step S16 the first control unit 400 uses the inside of the medicine container 10 used when the mixed injection process for the preparation data selected in Step S14 is performed. It is determined whether or not the drug remains.
  • the said 1st control part 400 when performing the determination process which concerns here corresponds to a determination means. Specifically, the first control unit 400 determines the medicine container based on the medicine dispensing amount based on the preparation data and a predetermined amount of medicine stored in the medicine container 10 in the data storage unit 404. It is determined before the end of the co-infusion process whether or not a drug less than the predetermined amount remains in 10. Thereby, even before the mixed injection process is completed, the adjustment data that can use the remaining medicine is displayed when displaying the selection candidate to be the next target of the mixed injection process in step S181 or step S19 described later. It is possible to display with priority.
  • the first control unit 400 determines that the amount of the medicine to be dispensed is 30 ml and the amount to be dispensed. It is determined that 10 ml of medicine remains in the medicine container 10 based on the difference from 40 ml. In addition, when the amount of the medicine to be dispensed is 40 ml and the predetermined amount of the medicine container 10 is 30 ml, the first control unit 400 determines that the total amount of the two medicine containers 10 is 60 ml and the amount to be dispensed. It is determined that 20 ml of medicine remains in the medicine container 10 based on the difference from 40 ml.
  • the first control unit 400 determines that the drug remains in the drug container 10 (Yes side of S16)
  • the first control unit 400 shifts the process to step S17 and determines that no drug remains in the drug container 10. Then (No side of S16), the process is shifted to step S11.
  • the first control unit 400 determines whether or not a medicine remains in the medicine container 10 when the mixed injection process ends before the mixed injection process ends. Therefore, the process after step S17 is executed before the user starts preparation of the medicine and instrument necessary for the next mixed injection process.
  • the first control unit 400 causes the data storage unit 404 to store the remaining medicine information regarding the remaining medicine determined to remain in the step S16.
  • the remaining medicine information includes, for example, various types of information such as the type of remaining medicine, the remaining amount, the opening date and time, and the expiration date.
  • the remaining drug is a mixed drug
  • the remaining drug information includes, for example, various information such as components of the mixed drug (drug name, solvent name), solvent amount, remaining amount, opening date / time, and expiration date. included.
  • the data storage unit 404 is an example of a remaining amount storage unit.
  • the mixing ratio in the mixed drug is specified according to the drug name and the solvent amount, the case where the solvent amount is stored as the residual information will be described as an example.
  • the mixing ratio may be stored.
  • the first control unit 400 deletes each of the remaining medicine information stored in the data storage unit 404 on the condition that the expiration date of the remaining medicine information has passed, and includes the remaining medicine information in the remaining medicine information. It is conceivable that a control signal for discarding the corresponding medicine container 10 is input to the second control unit 500. Accordingly, the second control unit 500 controls the first robot arm 21 or the second robot arm 22 and discards the medicine container 10 whose expiration date has passed. At this time, the first control unit 400 follows the display order of the preparation data in the prescription display unit D2 displayed on the prescription selection screen M1 when there is no residual drug whose expiration date has passed. Update the display order.
  • Step S18 the first control unit 400 determines whether or not the remaining drug remaining in the drug container 10 is a mixed drug in which a plurality of drugs or solvents are mixed. .
  • the first control unit 400 determines that the remaining drug is the mixed drug (Yes side of S18)
  • the first control unit 400 moves the process to step S19 and determines that the remaining drug is not the mixed drug. (No side of S18), the process proceeds to step S181.
  • step S181 the first control unit 400 determines that among the selection candidates of the preparation data to be subjected to the mixed injection process, it remains in the medicine container 10 in the past mixed injection process in step S16. Preparation data that contains the same type of drug as the remaining drug as a prescription is displayed preferentially.
  • the first control unit 400 when executing the display process corresponds to a display control means. Specifically, the first control unit 400 selects the preparation data selection candidates in the display order in which the selection candidates of the preparation data including the same type of medicine as the prescription medicine remaining in the medicine container 10 are higher. Is displayed on the prescription selection screen M1 of the display 403.
  • the first control unit 400 uses the remaining drug in the remaining drug presence / absence display unit D21 corresponding to the preparation data in which the same type of drug as the remaining drug remaining in the drug container 10 is included as a prescription drug. Display information indicating that it is possible. Thereby, the user can grasp
  • the first control unit 400 searches whether there is preparation data in which a medicine of the same type as the remaining medicine remaining in the medicine container 10 is included as a prescription medicine. And when the said preparation data are obtained as a search result 1 or more, the said 1st control part 400 changes the display content of the said prescription selection screen M1 so that the display position of the preparation data may become the highest. Further, as a method for preferentially displaying preparation data in which the same kind of drug as the remaining drug remaining in the drug container 10 is included as a prescription drug, the first control unit 400 remains in the drug container 10. It is also conceivable to display only the preparation data containing the same type of drug as the remaining drug as a prescription drug on the display device 26. As a result, the user can easily confirm only the preparation data in which the remaining drug can be used.
  • the first control unit 400 determines the arrangement order of the plurality of pieces of preparation data according to the sort condition, as in step S12. Thereby, it is possible to display the candidate of the said preparation data which should be prioritized according to the said sort conditions on the uppermost stage.
  • the sorting condition is, for example, a condition in which the earlier one of the prescription drug administration date or preparation date of the preparation data is higher.
  • the sort condition may be a condition in which the prescription category of the preparation data is outpatient than the prescription category of the preparation data is hospitalized. Thereby, the user can easily grasp the order of the dispensing data to be prioritized according to the medication date and time, the preparation date and time, the prescription classification, and the like.
  • the first control unit 400 does not change the display content of the prescription selection screen M1. It is possible. In this case, the first control unit 400 determines that the remaining medicine cannot be used, and does not place the medicine container 10 on the placement shelf 33, but stores the medicine container 10 in the garbage storage. It is also conceivable to transmit a control signal for causing the chamber 13a to be discarded to the second control unit 500.
  • Step S19 the first control unit 400 gives priority to preparation data including prescription drugs having the same components and mixing ratio as the mixed drug remaining in the drug container 10. To display automatically.
  • the first control unit 400 when executing the display process corresponds to a display control means.
  • the first control unit 400 determines whether the mixing ratio is the same, for example, according to the drug name and solvent amount stored in the remaining information and the drug name and solvent amount in the preparation data. To do.
  • the first control unit 400 displays, as in the step S181, higher-order preparation data including a prescription drug containing a drug having the same component and mixing ratio as the remaining drug remaining in the drug container 10.
  • the preparation data selection candidates are displayed on the prescription selection screen M1 of the display 403 in order.
  • the first control unit 400 displays the remaining drug in the remaining drug presence / absence display unit D21 corresponding to preparation data in which a drug having the same component and mixing ratio as the remaining drug remaining in the drug container 10 is included as a prescription drug.
  • Information indicating that it is possible to use is displayed.
  • step S19 as in step S181, when there are a plurality of the prepared data, the first control unit 400 determines the arrangement order of the plurality of prepared data according to the sorting condition.
  • the second control unit 500 determines whether or not the medicine remains in the medicine container 10 based on the weight of the medicine container 10 after the mixed injection processing is performed in Step S16. It is possible to judge whether. Specifically, the second control unit 500 places the drug container 10 on the weighing meter 35 using the first robot arm 21 or the second robot arm 22 after the mixed injection process is completed, and the drug The weight of the container 10 is measured. The second control unit 500 calculates the difference between the empty weight of the medicine container 10 stored in the medicine master and the weight of the medicine container 10 after the mixed injection process is performed. It is possible to detect the remaining amount of the medicine in the medicine container 10 after execution of the mixed injection process.
  • the second control unit 500 when executing the detection process is an example of a remaining amount detection unit.
  • the first control unit 400 preferentially displays the preparation data that can use the remaining medicine based on the remaining amount of the remaining medicine actually remaining in the medicine container 10 after the mixed injection process.
  • the detection method of the residual amount of the medicine in the medicine container 10 is not limited to this.
  • the medicine container 10 is imaged using a camera, and the medicine in the medicine container 10 is detected based on the captured image. It is also conceivable to detect the remaining amount.
  • the second control unit 500 may determine the amount of medicine (medicine in the syringe 11) acquired based on the weight of the syringe 11 measured by the weighing meter 35 or an image captured by the syringe confirmation camera 42. It is also possible to detect the remaining amount of the medicine in the medicine container 10 by calculating the difference between the amount extracted from the container 10 and the predetermined amount of the medicine container 10.
  • step S21 the second control unit 500 determines whether the preparation data is input from the first control unit 400.
  • the said 2nd control part 500 judges that the said preparation data was input (Yes side of S21)
  • it will transfer a process to step S22.
  • the second controller 500 repeatedly executes the determination process of step S21 until the preparation data is input (No side of S21).
  • Step S22 is it possible for the second control unit 500 to use the remaining medicine remaining in the mixed injection process performed in the past in the mixed injection process for the preparation data? Judge whether or not.
  • the second control unit 500 includes, in a prescription drug, the same type of drug as the remaining drug based on the remaining drug information stored in the data storage unit 404 by the first control unit 400. It is determined whether or not the dispensing data has been selected as the target of the mixed injection process. Further, the second controller 500 determines whether or not the content of the remaining medicine information satisfies a preset use condition.
  • the use condition is, for example, that the expiration date of the remaining medicine stored in the remaining medicine information has not passed, or that a predetermined time has not passed since the opening date of the remaining medicine. Thereby, for example, it is possible to set as the use condition that the expiration date of the remaining drug has not passed, and to set only the remaining drug for which the expiration date has not passed as the target of use.
  • the second control unit 500 uses the dispensing data including the same type of drug as the remaining drug in the prescription drug as the target of the mixed injection process, and the usage condition in which the content of the remaining drug information is set in advance. If the condition is satisfied, it is determined that the remaining drug can be used. This makes it possible to automatically exclude the use of the remaining medicine when the use conditions are not satisfied.
  • the first control unit 400 determines whether or not the remaining drug can be used, and whether or not the second control unit 500 can use the remaining drug from the first control unit 400. A control signal may be received.
  • the second control unit 500 after the use condition is calculated based on the preparation data and the predetermined amount of the medicine container 10 and the remaining amount of the medicine remaining in the medicine container 10. It is also conceivable that the difference between the remaining amount of the remaining medicine in the medicine container 10 detected by the above is within a preset range. Thereby, the difference between the remaining amount of the remaining medicine actually remaining in the medicine container 10 and the calculated value (predicted value) of the remaining amount based on the preparation data and the predetermined amount of the medicine container 10 is obtained. When the predetermined allowable amount is exceeded, it is possible to prevent the use of the remaining drug.
  • the medicine when the medicine is aspirated from the medicine container 10 by the syringe 11, the medicine leaks, and the remaining amount of the remaining medicine actually remaining in the medicine container 10 after the co-infusion processing is smaller than the calculated value.
  • the usage conditions are calculated based on the preparation data and the predetermined amount of the medicine container 10, and the remaining amount of the medicine in the medicine container 10 and the syringe confirmation camera during the mixed injection process.
  • the difference between the amount of medicine sucked into the syringe 11 imaged at 42 and the remaining amount of the remaining medicine in the medicine container 10 calculated based on the predetermined amount of the medicine container 10 is preset. It is also possible to include being within range.
  • the second control unit 500 If it is determined that the remaining drug can be used (Yes in S22), the process proceeds to step S23. If it is determined that the remaining drug cannot be used (No in S22), the process proceeds to step S221. Transition.
  • step S221 the second control unit 500 controls the mixed injection processing unit 300 based on the preparation data input from the first control unit 400 to thereby remove the infusion bag from the drug container 10.
  • the normal mixed injection process of injecting the drug into the No. 12 is executed. Specifically, in the mixed injection process, the second control unit 500 sucks the medicine indicated in the preparation data from one or a plurality of the medicine containers 10 placed on the container 101 by the syringe 11, The syringe 11 is injected into the infusion bag 12.
  • Step S23 the second control unit 500 uses the remaining medicine by controlling the mixed injection processing unit 300 based on the preparation data input from the first control unit 400. Then, the exceptional mixed injection process for injecting the drug into the infusion bag 12 is executed. That is, the second control unit 500 determines the remaining drug in the mixed injection process when the preparation data including the same type of drug as the remaining drug is selected as the target of the mixed injection process and satisfies the use condition. Execute the process to be used.
  • the said 2nd control part 500 when performing the process which concerns here corresponds to a residual medicine use means.
  • the second control unit 500 transfers the medicine indicated in the preparation data from the medicine container 10 placed on the placing table 33 in step S25 described later.
  • the syringe 11 is aspirated and injected from the syringe 11 into the infusion bag 12.
  • the second control part 500 is provided with one or a plurality of medicines placed on the medicine placement section 102.
  • the mixed injection process is continued using the medicine in the medicine container 10.
  • step S24 the second control unit 500 determines whether or not the medicine remains in the medicine container 10.
  • the determination process in step S24 may be the same process as in step S16 executed by the first control unit 400, but indicates whether or not the remaining medicine is generated from the first control unit 400.
  • a control signal may be received.
  • step S24 when the second control unit 500 determines that the medicine remains (Yes side of S24), the process proceeds to step S25, and when it is determined that the medicine does not remain (No side of S24), The process proceeds to step S241.
  • Step S25 When the drug remains in the drug container 10, in the subsequent step S25, the second control unit 500 controls the first robot arm 21 so that the drug container 10 can be used again. Then, it is placed on the placement shelf 33.
  • the second control unit 500 includes the name of the medicine, the remaining amount of the medicine in the medicine container 10, the placement position of the medicine container 10, the opening date and time of the medicine container 10, and the inside of the medicine container 10 Various information such as the expiration date of the remaining medicine is stored in the data storage unit 504.
  • Step S241> On the other hand, if no medicine remains in the medicine container 10, the second control unit 500 discards the medicine container 10 in the garbage storage chamber 13a by the first robot arm 21 in Step S241. That is, when the medicine in the medicine container 10 is not used up, the medicine container 10 is returned to the placement shelf 33, and when the medicine in the medicine container 10 is used up, the medicine container 10 is discarded. .
  • the mixed injection control device 100 executes the mixed injection management process and the mixed injection control process, so that the remaining medicine remaining in the previous mixed injection process can be used.
  • Preparation data is preferentially displayed as a selection candidate for the next mixed injection process.
  • the mixed injection device 1 can make the user aware of the preparation data that can use the remaining drug as the target of the next mixed injection process, so that the drug in the drug container 10 can be efficiently used. Can support use.
  • FIG. 22 is a diagram for explaining an actual operation example when the mixed injection management process and the mixed injection control process are executed by the mixed injection control apparatus 100.
  • 22A shows an example of preparation data
  • FIG. 22B shows an example of residual drug information
  • FIGS. 22C to 22E show examples of display of a part of the prescription display part D2. Note that the information shown in FIG. 22 omits items of information that are less relevant to the present case for convenience of explanation.
  • preparation data Rp1 to Rp4 are input to the first control unit 400 as selection candidates for the dispensing data to be subjected to the mixed injection process.
  • a predetermined amount of the ampule 10A containing a medicine having a medicine name of “5-FU injection 1000 mg”, a dispensing amount of “15 ml”, and the medicine name “5-FU injection 1000 mg”. Is shown to be “20 ml”.
  • the ampule in which the drug name to be prepared is “Kiloside N (registered trademark) Note 1 g”
  • the amount to be dispensed is “50 ml”
  • the drug name “Kiloside N Note 1 g” is accommodated. It is shown that the default amount of 10A is “50 ml”.
  • the first control unit 400 obtains a predetermined amount corresponding to the drug name “5-FU injection 1000 mg”, “Kiloside N injection 1 g”, and the like from the medicine master stored in the data storage unit 404. May be. Further, the first control unit 400 may acquire the predetermined amount from the barcode of the medicine container 10 by the barcode reader 34b.
  • the first control unit 400 When the first control unit 400 selects the preparation data Rp1 as the target of the mixed injection process, the first control unit 400 calculates a difference (5 ml) between the payout amount and the predetermined amount. . Accordingly, the first control unit 400 determines that the drug name “5-FU injection 1000 mg” remains “5 ml” in the ampoule 10A, and informs that information about the remaining medicine (see FIG. 22B). Is stored in the data storage unit 404. In the remaining medicine information shown in FIG. 22 (B), the medicine with the medicine name “5-FU injection 1000 mg” remains in the ampoule 10A by the remaining amount “5 ml”, and the opening date is “2013/02/15”. 11 o'clock ”and the expiration date is“ 13 o'clock 2013/02/15 ”.
  • the case where the prescription amount is equal to or less than the predetermined amount of the ampule 10A and the ampule 10A used is one will be described as an example.
  • the prescription amount exceeds the predetermined amount of the ampule 10A a plurality of the ampules 10A are used, and as a result, the medicine remains in one ampule 10A.
  • the prescription amount of the preparation data Rp1 is “30 ml”
  • two ampoules 10A are loaded in the container 101.
  • the first control unit 400 determines that the second ampule 10A has a drug of “10 ml” based on the difference between “40 ml” which is the total amount of the two ampules 10A and “30 ml” of the prescription amount. Judged to remain.
  • the first control unit 400 includes, as a prescription drug, the same kind of drug as the remaining drug of the drug name “5-FU injection 1000 mg” indicated in the remaining drug information in the preparation data Rp2 to Rp4. If the mixed injection process is performed on the preparation data Rp3 and Rp4, it is determined that the remaining drug can be used.
  • the first control unit 400 rearranges the preparation data Rp3 and Rp4 among the preparation data Rp2 to Rp4 above the preparation data Rp2, and the prescription selection screen. M1 (see FIG. 20) is preferentially displayed.
  • the first control unit 400 displays “O” on the remaining drug presence / absence display unit D21 (see FIG. 20) on the prescription selection screen M1, thereby preparing the preparation. It is displayed that the remaining drug can be used for data Rp3 and Rp4. Thereby, the user recognizes that the remaining medicine can be used by making the preparation data Rp3 and Rp4 displayed at the top in the prescription selection screen M1 the target of the next mixed injection process. be able to.
  • two ampoules 10A are required. However, if “5 ml” of the drug “5-FU injection 1000 mg” remains as the remaining drug and the remaining drug can be used, in the mixed injection process for the preparation data Rp3, Only the ampule 10A needs to be newly loaded.
  • the predetermined amount of the ampoule 10A in which the medicine name to be prepared is “5-FU injection 1000 mg”, the dispensed amount is “5 ml”, and the medicine name “5-FU injection 1000 mg” is accommodated. Is shown to be “20 ml”.
  • the mixed injection process for the preparation data Rp4 one ampoule 10A is required.
  • the ampoule 10A is used in the mixed injection process for the preparation data Rp4. There is no need to load a new one.
  • the first control unit 400 preferentially displays the preparation data, that is, the preparation data Rp4, in which the amount of the remaining medicine is sufficient to be dispensed.
  • the first control unit 400 only displays the preparation data Rp3 and Rp4 in order to preferentially display the preparation data Rp3 and Rp4 among the preparation data Rp2 to Rp4. Can be displayed on the prescription selection screen M1. Further, as shown in FIG. 22 (E), the first control unit 400, when a prescription date for a patient is set in advance for the preparation data Rp3 and Rp4, that is, the earlier of the prescription date, that is, the preparation It is also conceivable that the data Rp4 is preferentially displayed at the top.
  • the first control unit 400 determines the presence or absence of the remaining drugs in each of the mixed injection processes, and at least the remaining drugs It is conceivable to preferentially display the preparation data including one kind of medicine as the prescription medicine. In addition, when there are a plurality of types of the remaining drugs, the first control unit 400 may display preparation data having a large number of drugs of the same type as the remaining drugs included as prescription drugs at the top.
  • FIG. 23 is a diagram for explaining another actual operation example when the mixed injection management process and the mixed injection control process are executed by the mixed injection control apparatus 100. It is.
  • FIG. 23A shows an example of preparation data
  • FIG. 23B shows an example of remaining medicine information
  • FIG. 23C shows a display example of a part of the prescription display part D2. Note that the information shown in FIG. 23 omits items of information that are less relevant to the present case for convenience of explanation.
  • preparation data Rp11 to Rp15 are input to the first control unit 400 as selection candidates for the dispensing data to be subjected to the mixed injection process.
  • the name of the drug to be prepared is “1 g for Gemzar (registered trademark) injection”, and the payout amount is “25 m”.
  • the solvent is“ 100 ml of physiological saline ”, and the amount of the solvent is“ 30 ml ”. That is, in the preparation data Rp11, the components of the mixed drug generated in the vial bottle 10B are the drug “1 g for Gemzar injection” and the solvent “100 ml of physiological saline”.
  • the name of the drug to be prepared is “2 mg for mitomycin (registered trademark) injection”, the amount to be dispensed is “5 ml”, the solvent is “100 ml of physiological saline”, and the amount of the solvent is “5 ml”.
  • the name of the drug to be prepared is “1 g for Gemzar injection”, the amount to be dispensed is “25 ml”, the solvent is “glucose injection 5% 100 ml”, and the amount of the solvent is “30 ml”.
  • the first control unit 400 determines whether or not the mixed medicine remains in the vial bottle 10B. To do. Specifically, the first control unit 400 determines whether or not the mixed medicine remains in the vial 10B according to the difference between the solvent amount and the dispensed amount. That is, in the mixed injection process, when a mixed medicine is generated in the medicine container 10, the first control unit 400 stores the amount of the mixed medicine generated in the medicine container 10 in the medicine container 10. To be taken as the prescribed amount of drug.
  • the first control unit 400 determines that the mixed drug of the drug “Gemzar injection 1 g” and the solvent “100 ml of physiological saline” remains, this is indicated as the remaining drug information (see FIG. 23B).
  • the data is stored in the data storage unit 404.
  • the remaining drug information shown in FIG. 23B only “5 ml” of the mixed drug obtained by mixing “30 ml” of the solvent “physiological saline 100 ml” with the drug name “Gemzar injection 1 g” remains in the vial bottle 10B. The effect is shown.
  • the first control unit 400 includes the same components as the mixed drug of the drug “Gemzar injection 1 g” and the solvent “physiological saline 100 ml” indicated in the residual drug information in the preparation data Rp12 to Rp15. If the mixed injection process is performed on the preparation data Rp14 including a drug in a mixture ratio as a prescription drug, it is determined that the remaining drug can be used. In addition, since the mixing ratio of the mixed drug is determined according to the amount of components included in the drug name and the solvent amount of the solvent, the first control unit 400 is configured when the drug name and the solvent amount are the same. It can be determined that the mixing ratio of the mixed drugs is the same.
  • the first control unit 400 rearranges the preparation data Rp14 among the preparation data Rp12 to Rp15 to be higher than the preparation data Rp12 and Rp13, so that the prescription selection screen is displayed. M1 is preferentially displayed. Further, as shown in FIG. 23 (C), the first control unit 400 displays “O” on the remaining drug presence / absence display unit D21 (see FIG. 20) on the prescription selection screen M1, thereby preparing the preparation. For data Rp14, it is displayed that the remaining drug can be used. Thereby, the user recognizes that the remaining drug can be used by setting the preparation data Rp14 displayed at the top in the prescription selection screen M1 as the target of the next mixed injection process. it can.
  • the first control unit 400 has a function of managing the remaining medicine in consideration of the mass of the medicine.
  • the first control unit 400 performs a first operation mode in which the mass of the medicine is taken into consideration and a second operation mode in which the mass of the medicine is not taken into account according to a user operation of the operation unit 405 Can be switched.
  • the data storage unit 404 of the first control unit 400 stores, for example, the mass per unit volume for each drug, the volume per unit mass for each drug, or the volume for each drug name in the drug master.
  • the first controller 400 may obtain the volume of the medicine based on the medicine master and derive the actual capacity of the mixed medicine.
  • the first control unit 400 runs short of the medicine container 10 based on the amount of medicine dispensed based on the preparation data and the remaining amount of the remaining medicine stored in the data storage unit 404. It is conceivable to have a deficient amount display function for displaying the number. Here, the first control unit 400 when executing such display processing corresponds to the deficient amount display means.
  • the first controller 400 determines whether or not only the remaining drug is sufficient when the drug indicated by the preparation data is injected into the infusion bag 12 using the remaining drug. When the drug is insufficient, the necessary number of the drug containers 10 is displayed. On the other hand, the first control unit 400 displays that it is not necessary to load the drug container 10 when the remaining drug is sufficient. According to such a configuration, when the user uses the remaining medicine, the user can easily grasp whether or not the medicine container 10 needs to be loaded and the number thereof, so that when using the remaining medicine, Therefore, it is not necessary to consider the number of the drug containers 10 that are insufficient.
  • the second controller 500 uses the unused medicine container 10 loaded according to the amount of medicine dispensed based on the preparation data after the remaining medicine is used. It is conceivable to have a return processing function for returning the medicine container 10 from a predetermined return port.
  • the said 2nd control part 500 when performing the return process which concerns here corresponds to a return process means.
  • the return port is an opening communicating with the medicine loading unit 200 side.

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Primary Health Care (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Le problème décrit par la présente invention est de proposer une unité de gestion d'injection-mélange, un dispositif d'injection-mélange et un programme de gestion d'injection-mélange pouvant contribuer à l'utilisation efficace d'un médicament, dont une quantité prédéterminée est stockée à l'intérieur d'un récipient de médicament. La solution selon l'invention porte sur un dispositif de gestion d'injection-mélange qui : détermine si un médicament, qui est indiqué dans des données de préparation, reste dans un récipient de médicament qui doit être utilisé dans un processus d'injection-mélange pour injecter le médicament d'un ou plusieurs récipients de médicament à un récipient de perfusion, les récipients de médicament comprenant une quantité prédéterminée du médicament ; et de préférence affiche, sur un moyen d'affichage, des données de préparation qui comprennent un médicament du même type qu'un médicament résiduel, qui a été déterminé comme restant dans le récipient de médicament dans le processus d'injection-mélange précédent, dans les médicaments prescrits, lesdites données de préparation étant choisies parmi des candidats pour les données de préparation qui sont destinées à servir d'objectif pour le processus d'injection-mélange.
PCT/JP2014/066611 2013-07-01 2014-06-24 Unité de gestion d'injection-mélange, dispositif d'injection-mélange et programme de gestion d'injection-mélange WO2015002011A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2014549843A JP5696822B1 (ja) 2013-07-01 2014-06-24 混注管理装置、混注装置、混注管理プログラム

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013-138502 2013-07-01
JP2013138502 2013-07-01

Publications (1)

Publication Number Publication Date
WO2015002011A1 true WO2015002011A1 (fr) 2015-01-08

Family

ID=52143590

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2014/066611 WO2015002011A1 (fr) 2013-07-01 2014-06-24 Unité de gestion d'injection-mélange, dispositif d'injection-mélange et programme de gestion d'injection-mélange

Country Status (2)

Country Link
JP (4) JP5696822B1 (fr)
WO (1) WO2015002011A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6251839B1 (ja) * 2017-09-26 2017-12-20 株式会社日本医化器械製作所 暴露防止箱、及び暴露防止箱を備えた作業台付排気装置
JP2018047229A (ja) * 2015-12-28 2018-03-29 株式会社湯山製作所 混注装置、プログラム
JP2018515304A (ja) * 2015-04-20 2018-06-14 ティーゲル バイオ カンパニー リミテッド 薬物伝達キット、及び薬物伝達体製造用器具と方法
JP2018535796A (ja) * 2015-12-04 2018-12-06 ケアフュージョン ３０３、インコーポレイテッド 自動薬物調合器のためのバイアルパックシステム
JP2019083886A (ja) * 2017-11-02 2019-06-06 株式会社湯山製作所 混注装置

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117593360A (zh) 2016-07-29 2024-02-23 里珍纳龙药品有限公司 具有集成电子视觉检查的组装线
JP7056517B2 (ja) * 2017-11-01 2022-04-19 株式会社湯山製作所 混注管理システム、混注管理プログラム、及び混注管理方法
JP7397274B2 (ja) * 2018-03-16 2023-12-13 株式会社湯山製作所 混注装置、混注方法、混注制御プログラム
WO2019230931A1 (fr) * 2018-05-31 2019-12-05 川崎重工業株式会社 Robot et procédé de commande de robot

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002165866A (ja) * 2000-12-01 2002-06-11 Yasuyuki Goto 薬剤分配システムおよび方法と薬剤収容容器及び薬剤量読み取り装置
JP2007014463A (ja) * 2005-07-06 2007-01-25 Aloka Co Ltd 自動調剤装置及び自動調剤装置における薬瓶の管理方法
WO2010058568A1 (fr) * 2008-11-21 2010-05-27 株式会社湯山製作所 Dispositif distributeur de comprimés
JP2012250016A (ja) * 2011-03-25 2012-12-20 Yuyama Manufacturing Co Ltd 混注装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002011073A (ja) * 2000-06-29 2002-01-15 Tosho Inc 薬剤カセット
US7753085B2 (en) * 2002-12-03 2010-07-13 Forhealth Technologies, Inc. Automated drug preparation apparatus including automated drug reconstitution
JP4398210B2 (ja) * 2003-09-12 2010-01-13 株式会社トーショー 薬品管理装置および薬品管理システム
JP4539962B2 (ja) * 2004-05-24 2010-09-08 株式会社トーショー 調剤支援システム
JP2006155072A (ja) * 2004-11-26 2006-06-15 Toshiba Sumiden Medical Information Systems Corp 電子カルテ薬物療法指示実施システム
JP4920924B2 (ja) * 2005-07-20 2012-04-18 テルモ株式会社 薬剤自動調剤システム
US8065035B2 (en) * 2007-05-02 2011-11-22 Carefusion 303, Inc. Automated medication handling system
US9033006B2 (en) * 2010-09-17 2015-05-19 Nicholas J. Perazzo Oral syringe packaging system for hospital pharmacies
KR101889124B1 (ko) * 2011-08-08 2018-08-16 가부시키가이샤 유야마 세이사쿠쇼 혼주 장치
JP5860680B2 (ja) * 2011-11-22 2016-02-16 日立アロカメディカル株式会社 水薬調剤装置
JP6052487B2 (ja) * 2012-07-06 2016-12-27 株式会社タカゾノテクノロジー 水剤供給装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002165866A (ja) * 2000-12-01 2002-06-11 Yasuyuki Goto 薬剤分配システムおよび方法と薬剤収容容器及び薬剤量読み取り装置
JP2007014463A (ja) * 2005-07-06 2007-01-25 Aloka Co Ltd 自動調剤装置及び自動調剤装置における薬瓶の管理方法
WO2010058568A1 (fr) * 2008-11-21 2010-05-27 株式会社湯山製作所 Dispositif distributeur de comprimés
JP2012250016A (ja) * 2011-03-25 2012-12-20 Yuyama Manufacturing Co Ltd 混注装置

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515304A (ja) * 2015-04-20 2018-06-14 ティーゲル バイオ カンパニー リミテッド 薬物伝達キット、及び薬物伝達体製造用器具と方法
US10391233B2 (en) 2015-04-20 2019-08-27 Tgel Bio Co., Ltd. Drug delivery kit, and apparatus and method for preparing drug delivery system
JP2018535796A (ja) * 2015-12-04 2018-12-06 ケアフュージョン ３０３、インコーポレイテッド 自動薬物調合器のためのバイアルパックシステム
US11246803B2 (en) 2015-12-04 2022-02-15 Carefusion 303, Inc. Vial puck system for automatic drug compounder
US11622913B2 (en) 2015-12-04 2023-04-11 Carefusion 303, Inc. Vial puck system for automatic drug compounder
JP2018047229A (ja) * 2015-12-28 2018-03-29 株式会社湯山製作所 混注装置、プログラム
JP6251839B1 (ja) * 2017-09-26 2017-12-20 株式会社日本医化器械製作所 暴露防止箱、及び暴露防止箱を備えた作業台付排気装置
JP2019058338A (ja) * 2017-09-26 2019-04-18 株式会社日本医化器械製作所 暴露防止箱、及び暴露防止箱を備えた作業台付排気装置
JP2019083886A (ja) * 2017-11-02 2019-06-06 株式会社湯山製作所 混注装置
JP7095260B2 (ja) 2017-11-02 2022-07-05 株式会社湯山製作所 混注装置

Also Published As

Publication number Publication date
JPWO2015002011A1 (ja) 2017-02-23
JP2015062824A (ja) 2015-04-09
JP6583492B2 (ja) 2019-10-02
JP6365312B2 (ja) 2018-08-01
JP5696822B1 (ja) 2015-04-08
JP2018143882A (ja) 2018-09-20
JP2019217336A (ja) 2019-12-26

Similar Documents

Publication Publication Date Title
JP6583492B2 (ja) 混注管理装置、混注装置、混注管理プログラム
JP7014270B2 (ja) 混注装置、プログラム
JP6364833B2 (ja) 注射針、注射器、混注装置、混注方法
JP2023155508A (ja) 混注装置
JP2024009327A (ja) 混注装置、混注方法、混注制御プログラム
JP6098704B2 (ja) 混注装置、混注制御プログラム
JP7095260B2 (ja) 混注装置
JP6772706B2 (ja) 混注装置
JP7401779B2 (ja) 混注制御装置、混注制御プログラム、混注システム、混注装置
JP2019033790A (ja) 混注制御装置、混注装置、混注制御プログラム

Legal Events

Date Code Title Description
ENP Entry into the national phase

Ref document number: 2014549843

Country of ref document: JP

Kind code of ref document: A

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14819943

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 14819943

Country of ref document: EP

Kind code of ref document: A1