WO2011072149A1 - Dispositif de retrait de matériau doté d'une efficacité de capture de matériau améliorée et procédés d'utilisation afférents - Google Patents

Dispositif de retrait de matériau doté d'une efficacité de capture de matériau améliorée et procédés d'utilisation afférents Download PDF

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Publication number
WO2011072149A1
WO2011072149A1 PCT/US2010/059740 US2010059740W WO2011072149A1 WO 2011072149 A1 WO2011072149 A1 WO 2011072149A1 US 2010059740 W US2010059740 W US 2010059740W WO 2011072149 A1 WO2011072149 A1 WO 2011072149A1
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WO
WIPO (PCT)
Prior art keywords
catheter
cutting element
collection chamber
distal
lumen
Prior art date
Application number
PCT/US2010/059740
Other languages
English (en)
Inventor
Zhiyong Zhang
John Moberg
Hussain Rangwala
Thomas Mcpeak
William Whealon
Richard Kusleika
Original Assignee
Fox Hollow Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fox Hollow Technologies, Inc. filed Critical Fox Hollow Technologies, Inc.
Priority to EP10796232.6A priority Critical patent/EP2509519B1/fr
Priority to RU2012121843/14A priority patent/RU2520801C2/ru
Priority to KR1020137032766A priority patent/KR20140006106A/ko
Priority to JP2012543286A priority patent/JP5511107B2/ja
Priority to KR1020127017894A priority patent/KR101398384B1/ko
Priority to CA2783301A priority patent/CA2783301C/fr
Priority to CN201080055972.0A priority patent/CN102695463B/zh
Priority to IN4977DEN2012 priority patent/IN2012DN04977A/en
Priority to AU2010328078A priority patent/AU2010328078B2/en
Publication of WO2011072149A1 publication Critical patent/WO2011072149A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00681—Aspects not otherwise provided for
    • A61B2017/00685—Archimedes screw
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320016—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes
    • A61B17/32002—Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes with continuously rotating, oscillating or reciprocating cutting instruments
    • A61B2017/320032—Details of the rotating or oscillating shaft, e.g. using a flexible shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B2017/320064—Surgical cutting instruments with tissue or sample retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3205—Excision instruments
    • A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
    • A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
    • A61B2017/320791—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter with cutter extending outside the cutting window

Definitions

  • the present invention relates to catheters used to remove material from a site in a body lumen. More particularly, this invention pertains to catheters capable of capturing the material removed from the site.
  • Atherosclerosis is a progressive disease of the vascular system whereby atheroma is deposited on the inner walls of blood vessels. Over time atheromatous deposits can become large enough to reduce or occlude blood flow through the vessels, leading to symptoms of low blood flow such as pain in the legs (on walking or at rest), skin ulcer, angina (at rest or exertional), and other symptoms. To treat this disease and improve or resolve these symptoms it is desirable to restore or improve blood flow through the vessel.
  • Atherectomy catheters can be used to remove atheromatous deposits from the blood vessel and can present an ideal solution when the atheromatous debris removed from the vessel is captured and removed from the body.
  • the invention provides an atherectomy catheter, comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and a part for propelling fluid distally in the tissue collection chamber, the part being selected from the group consisting of: (i) a drive shaft having a proximal end and a distal portion, the proximal end being attached to the cutting element and a propeller being attached to the distal portion; and (ii) a paddle attached to the cutting element.
  • the invention provides a method of recirculating fluid in an atherectomy catheter comprising: providing an atherectomy catheter, the atherectomy catheter comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element, the tissue collection chamber having vent holes; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and moving fluid out of the tissue collection chamber through the vent holes such that a negative pressure is created inside the tissue collection chamber and this negative pressure causing fluid to enter the tissue collection chamber through the opening of the body of the catheter.
  • the invention provides a method of removing material from a body lumen, the method comprising: providing an atherectomy catheter, the atherectomy catheter comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and a lumen configured to direct fluid into the tissue collection chamber; placing the catheter in the body lumen; and moving the catheter in the body lumen to contact the cutting element with the material in the body lumen.
  • the invention provides a method of removing material from a body lumen, the method comprising: providing an atherectomy catheter, the atherectomy catheter comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and a part for propelling fluid distally in the tissue collection chamber, the part being selected from the group consisting of: (i) a drive shaft having a proximal end and a distal portion, the proximal end being attached to the cutting element and a propeller being attached to the distal portion; and (ii) a paddle attached to the cutting element; placing the catheter in the body lumen; and moving the catheter in the body lumen to contact the cutting element with the material in the body lumen.
  • FIG. 1 illustrates a partial isometric view of an atherectomy catheter.
  • FIG. 2 illustrates an isometric cross-sectional view of a portion of the atherectomy catheter illustrated in FIG. 1 with a cutting element in a stored position.
  • FIG. 4 illustrates an isometric view of an embodiment of a cutting element.
  • FIG. 8 illustrates an isometric view of another embodiment of a cutting element.
  • the invention provides an atherectomy catheter, comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and a lumen configured to direct fluid into the tissue collection chamber.
  • the lumen directs fluid in a distal direction into the tissue collection chamber.
  • the cutting element has a cup- shaped surface, the cup- shaped surface being configured to re-direct tissue cut by the cutting edge in a distal direction when the cup-shaped surface moves in the distal direction.
  • the lumen has a distal opening on the cup- shaped surface of the cutting element.
  • the lumen has a distal opening on the cup- shaped surface of the cutting element.
  • the distal opening is positioned at a longitudinal axis of the cutting element.
  • the tissue collection chamber comprises vent holes.
  • the tissue collection chamber comprises 10 to 200 vent holes.
  • the vent holes have a diameter of from 25 to 200 microns.
  • the cutting element is movable between a stored position and a cutting position relative to the opening.
  • the part for propelling fluid distally in the tissue collection chamber is a drive shaft having a proximal end and a distal portion, the proximal end being attached to the cutting element and a propeller being attached to the distal portion.
  • the propeller is located distally of the opening and proximally of the distal end of the collection chamber. In an embodiment, the propeller is located immediately distally of the opening. In an embodiment, the propeller is located in the distal half of the collection chamber.
  • the part for propelling fluid distally in the tissue collection chamber is a paddle attached to the cutting element.
  • the paddle is a wire that is twisted in a helical configuration.
  • the wire has a rectangular cross section.
  • the wire has a thickness from 0.002 to 0.020 inch (0.0051 to 0.051 cm).
  • wire width is from 0.010 to 0.075 inch (0.025 to 0.19 cm).
  • the paddle has a wire width that is from 20 to 95 percent of an inside diameter of the collection chamber.
  • the paddle has a longitudinal length that is at least 50 percent of the longitudinal length of the collection chamber.
  • the collection chamber comprises a portion at a distal end that can be opened to remove cut material and particles.
  • the cutting element is movable between a stored position and a cutting position relative to the opening.
  • the invention provides a method of recirculating fluid in an atherectomy catheter comprising: providing an atherectomy catheter, the atherectomy catheter comprising: a body having an opening; a rotatable shaft coupled to the body; a tissue collection chamber coupled to the body and positioned distal to the cutting element, the tissue collection chamber having vent holes; a cutting element coupled to the rotatable shaft, the cutting element having a cutting edge; and moving fluid out of the tissue collection chamber through the vent holes such that a negative pressure is created inside the tissue collection chamber and this negative pressure causing fluid to enter the tissue collection chamber through the opening of the body of the catheter.
  • the catheter comprises a lumen configured to direct fluid into the tissue collection chamber.
  • the present invention provides an improved atherectomy catheter having features for directing particles generated by a cutting element into a collection chamber. Methods of directing the cut material from a blood vessel lumen into a collection chamber are also provided.
  • the cutting element has a sharp cutting edge that surrounds a cup- shaped surface. Cut material is directed into the collection chamber by the cup- shaped surface and by fluid flow.
  • the raised element 26 helps to break up hard tissue and plaque by applying a relatively blunt striking force to the hard tissue or plaque since cutting such tissue with the cutting edge 22 may not be effective, and strips of such hard tissue may not be flexible enough to be redirected by cup- shaped surface 24 into collection chamber 12.
  • the raised elements 26 altogether occupy a relative small part of the cup-shaped surface 24. By sizing and positioning the raised elements 26 in this manner, the raised elements 26 do not interfere with the ability of the cutting element 4 cup- shaped surface 24 to cut and re-direct large strips of tissue into the tissue chamber while still providing the ability to break up hard tissue and plaque with raised element 26.
  • catheter 2 cuts softer atheroma from a vessel wall in relatively large strips and cup- shaped surface 24 directs these strips through opening 6 into collection chamber 12.
  • Smaller particles in some cases produced during the removal of harder or calcified atheroma, can be directed towards opening 6 by the cup- shaped surface 24 and can also be directed tangentially to the spinning cutting element outer edge 23, in some cases past opening 6 and in this event not collected in chamber 12.
  • catheter 2A is advanced through vessel V with cutting element 4 exposed through opening 6.
  • Cutting element 4 separates large fragments F of atheromatous material M from luminal surface LS of vessel V and cup-shaped surface 24 of cutting element 4 directs said fragments through opening 6 into interior 68 of collection chamber 12.
  • the fluid source forces pressurized fluid (such as physiological saline solution) through lumens 20A, 4A before, during or after rotation of cutting element 4, or any
  • the distal end of tube 7 can be oriented in any direction ranging from towards the side wall of collection chamber 12 to towards the distalmost end of collection chamber 12. In one embodiment the distal end of tube 7 is oriented towards distal region 68d of interior 68 of collection chamber 12. In other embodiments tube 7 has a one way valve that allows flow distally through the tube but prevents flow proximally through the tube so as to prevent blood or debris from entering tube 7 and potentially clogging the lumen of tube 7. In some embodiments the lumen diameter and length of tube 7 are sized so as to permit fluid flow rates of 0.5 to 50 cc/min, including 0.5, 1, 2, 5, 10, 20, or 50 cc/min, or other flow rates at a driving pressure of 50 psi (345
  • catheter 2C has improved material collection capability and is additionally comprised of lumen 4C in cutting element 4, lumen 20C and holes 20D in connecting shaft 20, impeller 9, inlet holes 32 in catheter 2 and vent holes 31 in the wall of collection chamber 12.
  • Cutting element 4 and connecting shaft 20 are attached by bonding, welding, molding, pressure fit, gasketed mechanical seal, or other means so as to form a leak-tight fluid connection between lumens 4C and 20C.
  • Holes 32 allow passage of fluid from lumen L of vessel V into lumen 21 and holes 20D allow passage of fluid from lumen 21 into lumen 20C.
  • Impeller 9 may be a separately fabricated component that is attached to connecting shaft 20 by welding, adhesive bond, or other means, or may be integrally formed from the shaft. In some embodiments the impeller is comprised of 1 to 10 or more turns, including 1, 2, 3, 4, 6, 8, or 10 turns (four turns 9e are illustrated in FIG. 7A). Pitch angles 9a of 10 to 75 degrees, including 10, 20, 30, 45, 60 or 75 degrees, are contemplated and pitch spacing 9b may be uniform or varied along the length of impeller. Impeller land width 9c may also vary along the length of the impeller.
  • dimensions of impeller 9 and diameter of lumen 21 may be varied so as to generate fluid flow rates of 0.5 to 50 cc/min, including 0.5, 1, 2, 5, 10, 20, or 50 cc/min, or other flow rates when the impeller is rotating at 1,000, 2,000, 4,000, 8,000, 16,000 or 24,000 RPM or at rotational speeds therebetween.
  • Vent holes 31 have structure and functional characteristics as described above for catheter 2 A.
  • catheter 2C is advanced through vessel V with cutting element 4 exposed through opening 6.
  • Cutting element separates large fragments F of atheromatous material M from luminal surface LS of vessel V and cup- shaped surface 24 of cutting element 4 directs said fragments through opening 6 into interior 68 of collection chamber 12.
  • Impeller 9, rotating in the direction indicated by arrow D draws fluid (such as blood) from lumen L of vessel through holes 32 and into lumen 21, pressurizes the fluid and forces the pressurized fluid through holes 20D, lumen 20C and lumen 4C during rotation of cutting element 4.
  • Small particles P generated by cutting element 4 acting on material M, are carried by fluid flow into distal region 68d of interior 68 of collection chamber 12.
  • Cutting element 40 can be used in place of cutting element 4 in any of catheters 2, 2 A, 2B, 2C or 2D.
  • Cutting element 40 is similar to cutting element 4 wherein the same or similar reference numbers of cutting element 40 refer to the same or similar structures of cutting element 4 and all discussion concerning the same or similar features of cutting element 4 are equally applicable here unless noted otherwise.
  • cutting element 40 is additionally comprised of one or more channels 42 and one or more holes 44.
  • E fluid such as blood enters channel 42 at outer edge 23 of cutting element 40 and exits distally through hole 44.
  • Channel 42 and hole 44 can be fabricated into cutter 40 by drilling, electro-discharge machining (EDM), or other means.
  • the number of channels and holes, channel widths 42W, channel lengths 42L, and hole 44 diameters may be varied so as to generate fluid flow rates of 0.5 to 50 cc/min, including 0.5, 1, 2, 5, 10, 20 or 50 cc/min, or other flow rates when cutting element 40 is rotating at 1,000, 2,000, 4,000, 8,000, 16,000 or 24,000 RPM or at rotational speeds therebetween.
  • cutting element 40 is rotated in the direction of arrow E during use within a vessel V as previously described for, for example, catheter 2A.
  • Cutting element 40 separates large fragments F of atheromatous material M from luminal surface LS of vessel V and cup-shaped surface 24 of cutting element 4 directs said fragments through opening 6 into interior 68 of collection chamber 12.
  • Cutting element 40 rotating in the direction indicated by arrow E, forces fluid (such as blood) from lumen L of vessel V into channel 42 and into hole 44 during rotation of the cutting element. Fluid exits hole 44 of cutting element 40 in the general direction of longitudinal axis LA and flows into interior 68 of collection chamber 12 and out of vent holes 31.
  • Small particles P generated by cutting element 40 acting on material M, are carried by fluid flow into distal region 68d of interior 68 of collection chamber 12.
  • catheter 2D refers to the same or similar structures of catheter 2 and all discussion concerning the same or similar features of catheter 2 are equally applicable here unless noted otherwise.
  • catheter 2D has improved material collection capability and is additionally comprised of drive shaft 33 and one or more propellers 34.
  • drive shaft 33 and propeller 34 may be comprised of metals such as stainless steel, cobalt-chromium-nickel- molybdenum-iron alloy (commercially available under the trade designation Elgiloy®), or other metals, or polymers such as polyester, polyamide, nylon 12, liquid crystal polymer, or other polymers.
  • Drive shaft 33 is attached to cup- shaped surface 24 of cutting element 4 and propeller 34 is attached to drive shaft 33, in some embodiments by welding, brazing, soldering, overmolding, mechanical interlock, adhesive bonding or other attachment means.
  • the pitch of propeller 34 may be varied so as to generate fluid flow rates of 0.5 to 50 cc/min, including 0.5, 1, 2, 5, 10, 20 or 50 cc/min, or other flow rates when propeller 34 is rotating at 1,000, 2,000, 4,000, 8,000, 16,000 or 24,000 RPM or at rotational speeds therebetween.
  • Vent holes 31 have structure and functional characteristics as described above for catheter 2A.
  • a paddle is attached to cup- shaped surface 24 of cutting element 4 instead of attaching drive shaft 33 and propeller 34 to cup-shaped surface 24.
  • Some embodiments of a paddle are illustrated in FIGS. 9A, 9B and 9C and labeled as paddles 35A, 35B and 35C, respectively.
  • the paddles 35A, 35B, 35C are illustrated with cutter 4 in a stored position.
  • the paddles may be comprised of wire having, in some embodiments, a rectangular cross section. The wire is twisted into a helical configuration as shown in the figures.
  • Paddles 35A, 35B, or 35C cause fluid in interior 68 of chamber 12 to move distally during rotation of cutting element 4.
  • wire width (the maximum distance between portions of the wire in the plane perpendicular to the longitudinal axis of the catheter), length and thickness as well as the pitch of the helix may be varied so as to generate fluid flow rates of 0.5 to 50 cc/min, including 0.5, 1, 2, 5, 10, 20, or 50 cc/min, or other flow rates when the impeller is rotating at 1,000, 2,000, 4,000, 8,000, 16,000 or 24,000 RPM or at rotational speeds therebetween.
  • the wire may be from 0.002 to 0.020 inch (0.0051 to 0.051 cm), including 0.002, 0.003, 0.004, 0.005, 0.007, 0.009, 0.011, 0.015 or 0.020 inch (0.0051, 0.0076, 0.010, 0.013, 0.018, 0.023, 0.028, 0.038 or 0.051 cm) thick
  • the wire width may be from 0.010 to 0.075 inch (0.025 to 0.19 cm), including 0.010, 0.015, 0.020, 0.025, 0.030, 0.040, 0.050 or 0.075 (0.025, 0.038, 0.051, 0.064, 0.076, 0.10, 0.13 or 0.19 cm), or at thicknesses, wire widths, or both therebetween.
  • FIG. 9 A illustrates paddle 35A comprised of rectangular cross section wire that has been twisted into a helix that is nearly as long as the length of collection chamber 12, having a wire width Dl that is 40% of the inside diameter of the collection chamber, and which has a uniform pitch length PI over the length of the paddle.
  • FIG. 9 A illustrates paddle 35A comprised of rectangular cross section wire that has been twisted into a helix that is nearly as long as the length of collection chamber 12, having a wire width Dl that is 40% of the inside diameter of the collection chamber, and which has a uniform pitch length PI over the length of the paddle.
  • catheters 2, 2A, 2B or 2C may additionally be comprised of drive shaft 33 and propeller 34.
  • catheters 2, 2A, 2B or 2C may additionally be comprised of paddles 35A, 35B, or 35C.
  • fragments F and particles P are removed from interior 68 of collection chamber 12 of catheter 2D by providing an opening at the distal end of collection chamber 12 and then rotating propeller 34 or paddle 35 to thereby expel debris.
  • catheters 2, 2 A, 2B or 2C may additionally be comprised of shaft 33 and propeller 34 or paddles 35A, 35B, or 35C and the interior of collection chamber 12 may be cleaned of debris as described above for catheter 2D.
  • a fluid recirculation circuit may be established. This is especially desirable in the case of total or near total obstruction of distal runoff in the vessel (see FIG. 10A) where, for example, material M completely occludes the vessel distal to the material removal catheter.
  • the flow rate of fluid out of vent holes 31 must exceed the volume of fluid entering into interior 68 of collection chamber 12 through lumen 4 A (catheter 2A), through tube 7 (catheter 2B), through lumen 4C (catheter 2C), through hole 44 of cutting element 40, or through combinations of these structures (where used).
  • a negative pressure will be established in the interior 68 of collection chamber 12 and fluid will flow into collection chamber 12 through opening 6, thereby drawing particles P generated by the cutting element into the interior 68 of collection chamber 12 (FIGS. 10A and 10B).
  • the invention is envisioned to be useful for removal of blockages in other blood flow lumens such as natural or artificial grafts, stent-grafts, anastomotic sites, fistulae, or other blood flow lumens.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgical Instruments (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

La présente invention concerne un cathéter amélioré d'athérectomie, pourvu de moyens destinés à diriger des particules produites par un élément de découpe dans une chambre de collecte. L'invention porte en outre sur des procédés permettant de diriger le matériau découpé depuis une lumière de vaisseau sanguin dans une chambre de collecte.
PCT/US2010/059740 2009-12-11 2010-12-09 Dispositif de retrait de matériau doté d'une efficacité de capture de matériau améliorée et procédés d'utilisation afférents WO2011072149A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
EP10796232.6A EP2509519B1 (fr) 2009-12-11 2010-12-09 Dispositif de retrait de matériau doté d'une efficacité de capture de matériau améliorée
RU2012121843/14A RU2520801C2 (ru) 2009-12-11 2010-12-09 Устройство для съема материала с улучшенной эффективностью захвата и способы применения
KR1020137032766A KR20140006106A (ko) 2009-12-11 2010-12-09 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법
JP2012543286A JP5511107B2 (ja) 2009-12-11 2010-12-09 改良された物質捕捉能率を有する物質除去デバイスおよび方法
KR1020127017894A KR101398384B1 (ko) 2009-12-11 2010-12-09 물질 포획 효율이 향상된 물질 제거 장치 및 사용 방법
CA2783301A CA2783301C (fr) 2009-12-11 2010-12-09 Dispositif de retrait de materiau dote d'une efficacite de capture de materiau amelioree et procedes d'utilisation afferents
CN201080055972.0A CN102695463B (zh) 2009-12-11 2010-12-09 具有提高的材料捕获效率的材料去除装置及使用方法
IN4977DEN2012 IN2012DN04977A (fr) 2009-12-11 2010-12-09
AU2010328078A AU2010328078B2 (en) 2009-12-11 2010-12-09 Material removal device having improved material capture efficiency and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28576809P 2009-12-11 2009-12-11
US61/285,768 2009-12-11

Publications (1)

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WO2011072149A1 true WO2011072149A1 (fr) 2011-06-16

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PCT/US2010/059740 WO2011072149A1 (fr) 2009-12-11 2010-12-09 Dispositif de retrait de matériau doté d'une efficacité de capture de matériau améliorée et procédés d'utilisation afférents

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US (4) US20110144673A1 (fr)
EP (1) EP2509519B1 (fr)
JP (2) JP5511107B2 (fr)
KR (2) KR20140006106A (fr)
CN (1) CN102695463B (fr)
AU (1) AU2010328078B2 (fr)
CA (1) CA2783301C (fr)
IN (1) IN2012DN04977A (fr)
RU (1) RU2520801C2 (fr)
WO (1) WO2011072149A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN102695463B (zh) 2015-01-14
JP5750492B2 (ja) 2015-07-22
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US20110144673A1 (en) 2011-06-16
JP5511107B2 (ja) 2014-06-04
JP2013513442A (ja) 2013-04-22
US20150216555A1 (en) 2015-08-06
RU2520801C2 (ru) 2014-06-27
US9028512B2 (en) 2015-05-12
US20180146980A1 (en) 2018-05-31
KR20120102108A (ko) 2012-09-17
AU2010328078A1 (en) 2012-06-14
CN102695463A (zh) 2012-09-26
AU2010328078B2 (en) 2013-07-04
JP2014042847A (ja) 2014-03-13
EP2509519B1 (fr) 2019-08-07
EP2509519A1 (fr) 2012-10-17
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US20130018397A1 (en) 2013-01-17
US9913659B2 (en) 2018-03-13
IN2012DN04977A (fr) 2015-09-25
CA2783301C (fr) 2015-02-24
CA2783301A1 (fr) 2011-06-16
RU2012121843A (ru) 2014-01-20

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