WO2011049414A3 - 지방조직 유래 성체 줄기세포 이동을 유도하는 방법 - Google Patents

지방조직 유래 성체 줄기세포 이동을 유도하는 방법 Download PDF

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WO2011049414A3
WO2011049414A3 PCT/KR2010/007329 KR2010007329W WO2011049414A3 WO 2011049414 A3 WO2011049414 A3 WO 2011049414A3 KR 2010007329 W KR2010007329 W KR 2010007329W WO 2011049414 A3 WO2011049414 A3 WO 2011049414A3
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stem cells
adult stem
adipose
derived
adipose tissue
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PCT/KR2010/007329
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English (en)
French (fr)
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WO2011049414A2 (ko
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라정찬
강성근
백선진
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주식회사 알앤엘바이오
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Application filed by 주식회사 알앤엘바이오 filed Critical 주식회사 알앤엘바이오
Priority to RU2012121191/10A priority Critical patent/RU2527182C2/ru
Priority to CN2010800588117A priority patent/CN102666840A/zh
Priority to US13/502,898 priority patent/US8808682B2/en
Priority to JP2012535141A priority patent/JP5657009B2/ja
Priority to EP10825239.6A priority patent/EP2511365A4/en
Priority to BR112012009540A priority patent/BR112012009540A2/pt
Publication of WO2011049414A2 publication Critical patent/WO2011049414A2/ko
Publication of WO2011049414A3 publication Critical patent/WO2011049414A3/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 지방조직 유래 성체줄기세포의 세포 이동(cell migration) 능력에 관한 것으로, 더욱 자세하게는 지방조직 유래 성체 줄기세포 및 이의 특정 분비물이, 특히, 특정 케모카인 또는 성장인자로 전처리된 지방조직 유래 성체 줄기세포가 보다 효과적으로 체내 질환 부위로 이동해 가는, 지방 줄기 세포의 신규 용도에 관한 것이다 본 발명에 따른 지방유래 성체 줄기세포 또는 특정 케모카인 또는 성장인자로 전처리된 지방조직 유래 성체 줄기세포 함유 조성물은 정맥 투여 등의 간단한 방법에 의해, 줄기세포의 질환부위로의 타겟팅(targetting)을 유도할 수 있으므로 세포치료제로서의 활용에 유용하다.
PCT/KR2010/007329 2009-10-23 2010-10-25 지방조직 유래 성체 줄기세포 이동을 유도하는 방법 WO2011049414A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
RU2012121191/10A RU2527182C2 (ru) 2009-10-23 2010-10-25 Способ индукции миграции стволовых клеток жировой ткани
CN2010800588117A CN102666840A (zh) 2009-10-23 2010-10-25 诱导脂肪源性成体干细胞迁移的方法
US13/502,898 US8808682B2 (en) 2009-10-23 2010-10-25 Method for inducing migration of adipose-derived adult stem cells
JP2012535141A JP5657009B2 (ja) 2009-10-23 2010-10-25 脂肪組織由来成体幹細胞遊走を誘導する方法
EP10825239.6A EP2511365A4 (en) 2009-10-23 2010-10-25 METHOD FOR INDUCING MIGRATION OF ADULT STEM CELLS DERIVED FROM ADIPOSE TISSUE
BR112012009540A BR112012009540A2 (pt) 2009-10-23 2010-10-25 composição e método para induzir a migração de células-tronco adultas derivadas de tecido adiposo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20090101117 2009-10-23
KR10-2009-0101117 2009-10-23

Publications (2)

Publication Number Publication Date
WO2011049414A2 WO2011049414A2 (ko) 2011-04-28
WO2011049414A3 true WO2011049414A3 (ko) 2011-09-09

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ID=43900858

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Application Number Title Priority Date Filing Date
PCT/KR2010/007329 WO2011049414A2 (ko) 2009-10-23 2010-10-25 지방조직 유래 성체 줄기세포 이동을 유도하는 방법

Country Status (8)

Country Link
US (1) US8808682B2 (ko)
EP (1) EP2511365A4 (ko)
JP (1) JP5657009B2 (ko)
KR (1) KR101223511B1 (ko)
CN (1) CN102666840A (ko)
BR (1) BR112012009540A2 (ko)
RU (1) RU2527182C2 (ko)
WO (1) WO2011049414A2 (ko)

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KR101583569B1 (ko) * 2013-05-15 2016-01-08 라정찬 정맥 투여용 줄기세포 조성물
CN104419659A (zh) * 2013-08-30 2015-03-18 翔宇生医科技股份有限公司 脂肪干细胞及其干细胞分泌物的培养与量产方法
RU2710373C2 (ru) * 2014-11-07 2019-12-26 Экзостемтех Ко., Лтд. Композиция, включающая экзосому, полученную из стволовых клеток, для индукции адипогенной дифференцировки, регенерации жировой ткани, отбеливания кожи или коррекции морщин
CN104531613B (zh) * 2014-11-17 2017-12-19 中国农业科学院北京畜牧兽医研究所 Wip1敲除在促进小鼠骨髓间充质干细胞迁移中的应用
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Also Published As

Publication number Publication date
KR101223511B1 (ko) 2013-01-31
EP2511365A4 (en) 2013-07-03
WO2011049414A2 (ko) 2011-04-28
EP2511365A2 (en) 2012-10-17
JP2013507956A (ja) 2013-03-07
CN102666840A (zh) 2012-09-12
BR112012009540A2 (pt) 2019-09-24
US8808682B2 (en) 2014-08-19
RU2012121191A (ru) 2013-11-27
US20120276044A1 (en) 2012-11-01
JP5657009B2 (ja) 2015-01-21
RU2527182C2 (ru) 2014-08-27
KR20110044722A (ko) 2011-04-29

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