MX340185B - Células precursoras cd27 1 derivadas de médula ósea para reparación cardíaca. - Google Patents

Células precursoras cd27 1 derivadas de médula ósea para reparación cardíaca.

Info

Publication number
MX340185B
MX340185B MX2013002381A MX2013002381A MX340185B MX 340185 B MX340185 B MX 340185B MX 2013002381 A MX2013002381 A MX 2013002381A MX 2013002381 A MX2013002381 A MX 2013002381A MX 340185 B MX340185 B MX 340185B
Authority
MX
Mexico
Prior art keywords
bone marrow
precursor cells
marrow derived
cardiac repair
repair
Prior art date
Application number
MX2013002381A
Other languages
English (en)
Other versions
MX2013002381A (es
Inventor
M Hare Joshua
K Mcniece Ian
Original Assignee
Univ Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Miami filed Critical Univ Miami
Publication of MX2013002381A publication Critical patent/MX2013002381A/es
Publication of MX340185B publication Critical patent/MX340185B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invención se refiere a una cantidad terapéuticamente efectiva de células precursoras de células madre mesenquimales (MSC) CD271+aisladas que se aíslan de la médula ósea de un sujeto y se cultivan bajo condiciones no adherentes para uso en la prevención o tratamiento de enfermedades o trastornos cardiovasculares, en tanto las células precursora de MSC CD271+son capaces de injertarse en un corazón en vivo en la zonas infartadas y de frontera.
MX2013002381A 2010-08-27 2011-08-29 Células precursoras cd27 1 derivadas de médula ósea para reparación cardíaca. MX340185B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37766110P 2010-08-27 2010-08-27
PCT/US2011/049542 WO2012027740A1 (en) 2010-08-27 2011-08-29 Bone marrow derived cd271 precursor cells for cardiac repair

Publications (2)

Publication Number Publication Date
MX2013002381A MX2013002381A (es) 2013-04-29
MX340185B true MX340185B (es) 2016-06-29

Family

ID=45723836

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013002381A MX340185B (es) 2010-08-27 2011-08-29 Células precursoras cd27 1 derivadas de médula ósea para reparación cardíaca.

Country Status (14)

Country Link
US (3) US20140023621A1 (es)
EP (1) EP2608797B1 (es)
JP (1) JP6061345B2 (es)
KR (1) KR101920891B1 (es)
CN (1) CN103221058B (es)
AU (1) AU2011293144B2 (es)
BR (1) BR112013004700B1 (es)
CA (1) CA2842181C (es)
ES (1) ES2556961T3 (es)
IL (1) IL224917A (es)
MX (1) MX340185B (es)
NZ (1) NZ608734A (es)
SG (1) SG188305A1 (es)
WO (1) WO2012027740A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012279995C1 (en) 2011-07-06 2019-10-24 Cell Therapy Limited Progenitor cells of mesodermal lineage
JP6090735B2 (ja) * 2012-03-02 2017-03-08 国立大学法人山口大学 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法
WO2013163539A1 (en) * 2012-04-26 2013-10-31 The Cohen Mcniece Foundation Human fetal heart derived stromal cells for treatment of patients following a myocardial infarction
WO2014022376A2 (en) 2012-08-01 2014-02-06 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells
JP6901823B2 (ja) 2012-08-01 2021-07-14 ユナイテッド セラピューティクス コーポレイション 間葉系幹細胞による肺動脈性高血圧症の処置
EP3878452B1 (en) * 2013-01-09 2023-09-20 United Therapeutics Corporation Treatment of vasculopathy with prostacyclin and mesenchymal stem cells
US10456943B2 (en) * 2014-12-03 2019-10-29 Urschel Laboratories, Inc. Machines and methods for cutting products and impellers therefor
BR112017012911B1 (pt) * 2014-12-23 2021-10-05 Mesoblast International Sàrl Método para tratamento de insuficiência cardíaca
JP6777840B2 (ja) * 2015-12-25 2020-10-28 北海道公立大学法人 札幌医科大学 脳梗塞の治療用医薬
CN106474456A (zh) * 2016-10-18 2017-03-08 广州赛莱拉干细胞科技股份有限公司 一种细胞制剂及其制备方法和应用
IL266175B2 (en) 2016-10-24 2024-01-01 United Therapeutics Corp Enhancement of immunomodulatory properties of MSC using treprostinil
EP3856203A4 (en) * 2018-09-27 2022-02-23 Biocardia, Inc. BONE MARROW DERIVED NEUROKININ 1 RECEPTOR POSITIVE (NK1R+) PROGENIOR CELLS FOR THERAPEUTIC APPLICATIONS
CN110302212A (zh) * 2019-07-17 2019-10-08 陶正博 一种用于治疗急性心肌梗死的细胞制剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009060840A (ja) * 2007-09-06 2009-03-26 Keio Gijuku ヒト間葉系幹細胞濃縮方法
WO2009140452A2 (en) * 2008-05-15 2009-11-19 University Of Miami Isolation of stem cell precursors and expansion in non-adherent conditions
US20110305673A1 (en) * 2008-11-12 2011-12-15 The University Of Vermont And State Agriculture College Compositions and methods for tissue repair

Also Published As

Publication number Publication date
US20180214486A1 (en) 2018-08-02
CN103221058B (zh) 2015-07-29
JP6061345B2 (ja) 2017-01-18
KR101920891B1 (ko) 2018-11-21
JP2013542178A (ja) 2013-11-21
AU2011293144B2 (en) 2015-04-23
KR20130106381A (ko) 2013-09-27
EP2608797B1 (en) 2015-09-23
BR112013004700B1 (pt) 2020-12-08
MX2013002381A (es) 2013-04-29
CN103221058A (zh) 2013-07-24
NZ608734A (en) 2014-09-26
WO2012027740A1 (en) 2012-03-01
AU2011293144A1 (en) 2013-04-18
CA2842181C (en) 2021-01-05
ES2556961T3 (es) 2016-01-21
US20140023621A1 (en) 2014-01-23
EP2608797A4 (en) 2014-01-22
IL224917A (en) 2017-02-28
US20230071551A1 (en) 2023-03-09
EP2608797A1 (en) 2013-07-03
CA2842181A1 (en) 2012-03-01
BR112013004700A2 (pt) 2017-07-04
SG188305A1 (en) 2013-04-30

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