BR112013004700A2 - método para prevenir ou tratar doenças ou distúrbios cardiovasculares - Google Patents

método para prevenir ou tratar doenças ou distúrbios cardiovasculares

Info

Publication number
BR112013004700A2
BR112013004700A2 BR112013004700A BR112013004700A BR112013004700A2 BR 112013004700 A2 BR112013004700 A2 BR 112013004700A2 BR 112013004700 A BR112013004700 A BR 112013004700A BR 112013004700 A BR112013004700 A BR 112013004700A BR 112013004700 A2 BR112013004700 A2 BR 112013004700A2
Authority
BR
Brazil
Prior art keywords
preventing
cardiovascular disease
treating cardiovascular
disorder
methods
Prior art date
Application number
BR112013004700A
Other languages
English (en)
Other versions
BR112013004700B1 (pt
Inventor
K Mcniece Ian
M Hare Joshua
Original Assignee
Univ Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Miami filed Critical Univ Miami
Publication of BR112013004700A2 publication Critical patent/BR112013004700A2/pt
Publication of BR112013004700B1 publication Critical patent/BR112013004700B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

método para prevenir ou tratar doenças ou distúrbios cardiovasculares. os métodos de isolamento de populações de células-tronco cd271^ +^ são importantes na prevenção ou tratamento de doenças cardiovasculares e reparação do tecido cardíaco. os métodos são aplicáveis a células-tronco de diferentes fontes e podem ser usados para tratar ou prevenir doenças ou reparação de tecidos em outras partes do organismo.
BR112013004700-3A 2010-08-27 2011-08-29 uso de células precursoras de células-tronco mesenquimais (msc) cd271+ BR112013004700B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37766110P 2010-08-27 2010-08-27
US61/377,661 2010-08-27
PCT/US2011/049542 WO2012027740A1 (en) 2010-08-27 2011-08-29 Bone marrow derived cd271 precursor cells for cardiac repair

Publications (2)

Publication Number Publication Date
BR112013004700A2 true BR112013004700A2 (pt) 2017-07-04
BR112013004700B1 BR112013004700B1 (pt) 2020-12-08

Family

ID=45723836

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013004700-3A BR112013004700B1 (pt) 2010-08-27 2011-08-29 uso de células precursoras de células-tronco mesenquimais (msc) cd271+

Country Status (14)

Country Link
US (3) US20140023621A1 (pt)
EP (1) EP2608797B1 (pt)
JP (1) JP6061345B2 (pt)
KR (1) KR101920891B1 (pt)
CN (1) CN103221058B (pt)
AU (1) AU2011293144B2 (pt)
BR (1) BR112013004700B1 (pt)
CA (1) CA2842181C (pt)
ES (1) ES2556961T3 (pt)
IL (1) IL224917A (pt)
MX (1) MX340185B (pt)
NZ (1) NZ608734A (pt)
SG (1) SG188305A1 (pt)
WO (1) WO2012027740A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2840307C (en) 2011-07-06 2021-10-19 Cell Therapy Limited Progenitor cells of mesodermal lineage
JP6090735B2 (ja) * 2012-03-02 2017-03-08 国立大学法人山口大学 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法
WO2013163539A1 (en) * 2012-04-26 2013-10-31 The Cohen Mcniece Foundation Human fetal heart derived stromal cells for treatment of patients following a myocardial infarction
CA2880811C (en) 2012-08-01 2021-12-07 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with prostacyclin-treated endothelial progenitor cells
WO2014022373A1 (en) 2012-08-01 2014-02-06 United Therapeutics Corporation Treatment of pulmonary arterial hypertension with mesenchymal stem cells
EP3878452B1 (en) 2013-01-09 2023-09-20 United Therapeutics Corporation Treatment of vasculopathy with prostacyclin and mesenchymal stem cells
US10456943B2 (en) * 2014-12-03 2019-10-29 Urschel Laboratories, Inc. Machines and methods for cutting products and impellers therefor
AU2015371011B2 (en) * 2014-12-23 2021-07-15 Mesoblast International Sàrl Prevention of progressive heart failure
BR112017012911B1 (pt) * 2014-12-23 2021-10-05 Mesoblast International Sàrl Método para tratamento de insuficiência cardíaca
JP6777840B2 (ja) * 2015-12-25 2020-10-28 北海道公立大学法人 札幌医科大学 脳梗塞の治療用医薬
CN106474456A (zh) * 2016-10-18 2017-03-08 广州赛莱拉干细胞科技股份有限公司 一种细胞制剂及其制备方法和应用
ES2927406T3 (es) 2016-10-24 2022-11-04 United Therapeutics Corp Potenciación de las propiedades inmunomoduladoras de las MSC mediante treprostinil
JP2022503847A (ja) * 2018-09-27 2022-01-12 バイオカーディア，インコーポレイテッド 治療適用のための骨髄由来ニューロキニン－１受容体陽性（ｎｋ１ｒ＋）前駆細胞
CN110302212A (zh) * 2019-07-17 2019-10-08 陶正博 一种用于治疗急性心肌梗死的细胞制剂及其制备方法
KR20220054359A (ko) * 2019-08-28 2022-05-02 아스텔라스 인스티튜트 포 리제너러티브 메디슨 혈관 질병을 치료하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009060840A (ja) * 2007-09-06 2009-03-26 Keio Gijuku ヒト間葉系幹細胞濃縮方法
US20110182866A1 (en) * 2008-05-15 2011-07-28 University Of Miami Isolation of stem cell precursors and expansion in non-adherent conditions
US20110305673A1 (en) * 2008-11-12 2011-12-15 The University Of Vermont And State Agriculture College Compositions and methods for tissue repair

Also Published As

Publication number Publication date
EP2608797B1 (en) 2015-09-23
EP2608797A1 (en) 2013-07-03
US20140023621A1 (en) 2014-01-23
EP2608797A4 (en) 2014-01-22
CA2842181A1 (en) 2012-03-01
KR101920891B1 (ko) 2018-11-21
BR112013004700B1 (pt) 2020-12-08
MX2013002381A (es) 2013-04-29
KR20130106381A (ko) 2013-09-27
AU2011293144A1 (en) 2013-04-18
WO2012027740A1 (en) 2012-03-01
JP2013542178A (ja) 2013-11-21
US20180214486A1 (en) 2018-08-02
NZ608734A (en) 2014-09-26
ES2556961T3 (es) 2016-01-21
IL224917A (en) 2017-02-28
AU2011293144B2 (en) 2015-04-23
SG188305A1 (en) 2013-04-30
US20230071551A1 (en) 2023-03-09
JP6061345B2 (ja) 2017-01-18
MX340185B (es) 2016-06-29
CN103221058B (zh) 2015-07-29
CA2842181C (en) 2021-01-05
CN103221058A (zh) 2013-07-24

Similar Documents

Publication Publication Date Title
BR112013004700A2 (pt) método para prevenir ou tratar doenças ou distúrbios cardiovasculares
BR112014031424A2 (pt) tratamento de células pluripotentes
CO6660423A2 (es) Composiciones y métodos para tratar la enfermedad de gaucher
BR112014031874A2 (pt) método para preparar células-tronco em concentração elevada
MX2019008428A (es) Inhibidores de glucosilceramida sintasa.
BR112014030682A2 (pt) diferenciação de células tronco embrionárias humanas em células pancreáticas endócrinas
BR112015011933A8 (pt) Composições bacterianas sinérgicas e métodos de produção e uso das mesmas
AR090339A1 (es) Metodos de pronostico, diagnostico y tratamiento de la fibrosis pulmonar idiopatica
BRPI0911176B8 (pt) método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea
SG11201405875PA (en) Methods and compositions for regenerating and repairing damaged tissue using nonviable irradiated or lyophilized pluripotent stem cells
IN2014MN00989A (pt)
EP2861238A4 (en) OPTIMIZED METHODS FOR GENERATING CARDIAC STEM CELLS FROM CARDIAC TISSUE AND THEIR USE IN CARDIAC THERAPY
EP2480565A4 (en) PEPTIDOMIMETIC MACROCYCLES
BR112013007069A2 (pt) métodos para tratar doença autoimune usando nanoesferas biocompatíveis e bioabsorvíveis
NI201200090A (es) Composiciones para tratar náusea y vómito centralmente mediados
MX2016005824A (es) Metodo de cultivo celular.
CY1124191T1 (el) Θεραπεια της νοσου μοσχευματος εναντια στον ξενιστη σε μεταμοσχευμενους ασθενεις
MX362098B (es) El uso de células derivadas de tejido del cordón umbilical y kits que contienen las mismas para el tratamiento de enfermedad vascular periférica.
BR112015009229A2 (pt) composição tendo como alvo a expressão de genes para plaquetas, célula tronco hematopoiética, uso da referida célula tronco e método in vitro ou ex vivo para gerar uma célula tronco modificada
BR112018070293A2 (pt) diferenciação de células-tronco pluripotentes em células do endoderma intestinal do intestino médio
MX2015008436A (es) Composiciones para permeabilizar celulas sanguineos fijos y sus usos.
MX365464B (es) Prodecimiento para preparar inhibidores de la glucosilceramida sintasa.
MX358726B (es) Biomarcador predictivo de supervivencia en el tratamiento de carcinoma de celulas renales.
IN2014DN08385A (pt)
BR112015000547A2 (pt) métodos para tratar tecido; e composição de tecido

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: JOSHUA M. HARE (US)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 29/08/2011, OBSERVADAS AS CONDICOES LEGAIS.