BRPI0911176B8 - método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea - Google Patents

método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea

Info

Publication number
BRPI0911176B8
BRPI0911176B8 BRPI0911176A BRPI0911176A BRPI0911176B8 BR PI0911176 B8 BRPI0911176 B8 BR PI0911176B8 BR PI0911176 A BRPI0911176 A BR PI0911176A BR PI0911176 A BRPI0911176 A BR PI0911176A BR PI0911176 B8 BRPI0911176 B8 BR PI0911176B8
Authority
BR
Brazil
Prior art keywords
red blood
blood cell
cell composition
treating
reducing dehydration
Prior art date
Application number
BRPI0911176A
Other languages
English (en)
Inventor
Erickson Anna
North Anne
Mufti Naheed
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Publication of BRPI0911176A2 publication Critical patent/BRPI0911176A2/pt
Publication of BRPI0911176B1 publication Critical patent/BRPI0911176B1/pt
Publication of BRPI0911176B8 publication Critical patent/BRPI0911176B8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/18Erythrocytes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215Disinfecting agents, e.g. antimicrobials for preserving living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A01N43/42Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N2300/00Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances

Abstract

método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea. a presente invenção refere-se a métodos para tratar composições de células sanguínea vermelha vermelha com um composto de inativação de patógeneo sob condições que forneçam inativação de patógeneo adequada ao mesmo tempo em que mantendo a vitalidade de célula. também fornecidos são métodos de reduzir a desidratação em células vermelhas sanguíneas, bem como composições de células sanguínea vermelha, bem como composições de célula sanguínea vermelha tratadas.
BRPI0911176A 2008-04-09 2009-04-09 método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea BRPI0911176B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US4366608P 2008-04-09 2008-04-09
US61/043,666 2008-04-09
US8703408P 2008-08-07 2008-08-07
US61/087,034 2008-08-07
PCT/US2009/040032 WO2009126786A2 (en) 2008-04-09 2009-04-09 Improved quenching methods for red blood cell pathogen inactivation

Publications (3)

Publication Number Publication Date
BRPI0911176A2 BRPI0911176A2 (pt) 2015-07-28
BRPI0911176B1 BRPI0911176B1 (pt) 2019-10-15
BRPI0911176B8 true BRPI0911176B8 (pt) 2021-05-25

Family

ID=41162599

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911176A BRPI0911176B8 (pt) 2008-04-09 2009-04-09 método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea

Country Status (16)

Country Link
US (3) US8900805B2 (pt)
EP (2) EP3257375A1 (pt)
JP (2) JP5916383B2 (pt)
KR (2) KR101742533B1 (pt)
CN (1) CN102046006B (pt)
AU (1) AU2009233807B2 (pt)
BR (1) BRPI0911176B8 (pt)
CA (1) CA2720824C (pt)
EA (1) EA023596B1 (pt)
ES (1) ES2636563T3 (pt)
HK (1) HK1157140A1 (pt)
IL (1) IL208431A (pt)
MX (1) MX2010011018A (pt)
SG (2) SG10201605663UA (pt)
WO (1) WO2009126786A2 (pt)
ZA (1) ZA201006936B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101742533B1 (ko) 2008-04-09 2017-06-01 세루스 코포레이션 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
EP3194576B1 (en) 2014-07-23 2020-11-18 Cerus Corporation Methods for preparing platelet products
KR20180012242A (ko) 2015-03-10 2018-02-05 뉴 헬스 사이언시즈 인코포레이티드 산소 감소 1회용 키트, 장치 및 이의 사용 방법
IL285359B2 (en) 2015-04-23 2024-01-01 Hemanext Inc Anaerobic blood storage containers
CA2985799A1 (en) 2015-05-18 2016-11-24 New Health Sciences, Inc. Methods for the storage of whole blood, and compositions thereof
CN108135936A (zh) 2015-06-26 2018-06-08 塞鲁斯公司 冷沉淀物组合物及其制备方法
US10799533B2 (en) 2015-10-23 2020-10-13 Cerus Corporation Plasma compositions and methods of use thereof
EP3463466B1 (en) * 2016-05-27 2022-02-16 Hemanext Inc. Anaerobic blood storage and pathogen inactivation method
IT201600079328A1 (it) * 2016-07-28 2018-01-28 Altergon Sa Metodo migliorato per la decontaminazione di materiale biologico mediante partizione e inattivazione
EA201991506A1 (ru) 2016-12-23 2020-01-23 Сирус Корпорейшн Системы и способы для тестирования и скрининга с использованием связанных с соединениями субстратов
EP3562493A1 (en) 2016-12-31 2019-11-06 Cerus Corporation Compositions and methods for preparation of red blood cells
US11235090B2 (en) 2017-03-03 2022-02-01 Cerus Corporation Kits and methods for preparing pathogen-inactivated platelet compositions
AU2018395525B2 (en) 2017-12-29 2023-09-14 Cerus Corporation Systems and methods for treating biological fluids
CA3107314A1 (en) * 2018-07-27 2020-01-30 Zata Pharmaceuticals, Inc. Method for pathogens, microorganisms, and parasites inactivation
MX2021003180A (es) 2018-09-20 2021-05-14 Cerus Corp Métodos y kits para preparar sangre entera con inactivación de patógenos.
WO2020264421A1 (en) 2019-06-28 2020-12-30 Cerus Corporation System and methods for implementing a biological fluid treatment device

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2402665A (en) 1942-11-12 1946-06-25 Du Pont Chemical process
IT1093275B (it) 1978-01-26 1985-07-19 Snam Progetti Composizione adatta alla purificazione del sangue e suoi impieghi
US4337269A (en) 1979-07-23 1982-06-29 Sutton Laboratories, Inc. Preservative compositions
US4727027A (en) 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4748120A (en) 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US5281579A (en) 1984-03-23 1994-01-25 Baxter International Inc. Purified virus-free hemoglobin solutions and method for making same
US4971760A (en) 1986-03-10 1990-11-20 University Of Southern California Novel method for disinfecting red blood cells, blood platelets, blood plasma, and optical corneas and sclerae
US4944920A (en) 1986-08-01 1990-07-31 University Of Southern California Novel method to treat blood
US4920143A (en) 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5094960A (en) 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5055485A (en) 1988-12-02 1991-10-08 New York Blood Center, Inc. Inactivation of viruses in cell- and protein-containing compositions using aryl diol epoxides
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5587490A (en) 1990-04-16 1996-12-24 Credit Managers Association Of California Method of inactivation of viral and bacterial blood contaminants
US5658722A (en) 1990-05-15 1997-08-19 New York Blood Center, Inc. Process for the sterilization of biological compositions using UVA1 irradiation
US5232844A (en) 1990-05-15 1993-08-03 New York Blood Center Photodynamic inactivation of viruses in cell-containing compositions
US5120649A (en) 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
US5753258A (en) 1990-10-19 1998-05-19 University Of Florida Artificial viral envelopes
GB9218581D0 (en) 1992-09-02 1992-10-14 Pall Corp Removal of unwanted fluids from processed blood products
AU698154B2 (en) 1993-06-23 1998-10-22 New York Blood Center, Inc., The System for viral inactivation of blood
US5591350A (en) 1994-04-15 1997-01-07 Pall Corporation Iodine disinfection method using a gaseous iodine treated porous medium
SE9402472L (sv) 1994-07-13 1996-01-14 Forskarpatent I Linkoeping Ab Modifierade ytor
US5522385A (en) 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US5660731A (en) 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US5691132A (en) 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
US5637451A (en) 1995-03-29 1997-06-10 New York Blood Center, Inc. Photodynamic treatment of red blood cells with phthalocyanines and red light at higher light fluence rates is protective of red blood cells
US6177441B1 (en) 1995-06-05 2001-01-23 Cerus Corporation Treating red blood cell solutions with anti-viral agents
EP0773716A4 (en) 1995-06-07 1999-08-04 Cerus Corp TREATMENT OF RED BLOOD CELL SOLUTIONS WITH ANTIVRAL ACTIVE SUBSTANCES
US20020192632A1 (en) 1995-06-07 2002-12-19 Hei Derek J. Method and devices for the removal of psoralens from blood products
AU703108B2 (en) 1995-06-07 1999-03-18 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
ATE451445T1 (de) 1995-06-07 2009-12-15 Cerus Corp Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten.
US6544727B1 (en) 1995-06-07 2003-04-08 Cerus Corporation Methods and devices for the removal of psoralens from blood products
AU7717396A (en) 1995-06-29 1997-02-05 Hemasure, Inc. Inactivation of pathogens using hydroxymethylamines
US6136586A (en) 1995-08-29 2000-10-24 Vi Technologies, Inc. Methods for the selective modification of viral nucleic acids
US6114108A (en) 1995-08-29 2000-09-05 V.I. Technologies, Inc. Methods and compositions for the selective modification of viral nucleic acids
AU723016B2 (en) 1995-11-06 2000-08-17 New York Blood Center, Inc., The Viral inactivation treatment of red blood cells using phthalocyanines and red light
WO1997018844A1 (en) 1995-11-21 1997-05-29 Pall Corporation Inactivation method and system in biological fluids
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US6514987B1 (en) 1997-01-06 2003-02-04 Cerus Corporation Frangible compounds for pathogen inactivation
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US6093725A (en) 1997-01-06 2000-07-25 Cerus Corporation Frangible compounds for pathogen inactivation
WO1998030545A1 (en) 1997-01-06 1998-07-16 Cerus Corporation Frangible compounds for pathogen inactivation
US6093564A (en) 1997-10-03 2000-07-25 V.I. Technologies, Inc. Methods and compositions for the selective modification of nucleic acids
AU745209B2 (en) 1998-01-06 2002-03-14 Cerus Corporation Methods for quenching pathogen inactivators in biological materials
US20030073650A1 (en) * 1998-07-21 2003-04-17 Heather Reddy Method and apparatus for inactivation of biological contaminants using photosensitizers
US6150109A (en) 1999-01-25 2000-11-21 V. I. TECHNOLOGIES, Inc. Lipophilic quenching of viral inactivating agents
US6288122B1 (en) 1999-02-23 2001-09-11 Icagen, Inc. Gardos channel antagonists
EP1284743A2 (en) 2000-05-31 2003-02-26 Cerus Corporation Preparation of a pathogen inactivated solution of red blood cells having reduced immunogenicity
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
CA2434256A1 (en) 2000-12-21 2003-07-31 David Cook Methods for inactivation of pathogens in biological materials
BRPI0518198B8 (pt) * 2004-10-29 2021-06-22 Cerus Corp método ex vivo para tratar uma composição de células hemácias para inativar um patógeno, se presente, bem como composição e kit
KR101742533B1 (ko) 2008-04-09 2017-06-01 세루스 코포레이션 적혈구 병원체 불활성화를 위한 개선된 퀀칭 방법

Also Published As

Publication number Publication date
CN102046006B (zh) 2014-09-24
EA023596B1 (ru) 2016-06-30
IL208431A (en) 2016-10-31
EA201071178A1 (ru) 2011-06-30
AU2009233807A1 (en) 2009-10-15
WO2009126786A3 (en) 2010-07-15
SG10201605663UA (en) 2016-09-29
CN102046006A (zh) 2011-05-04
WO2009126786A2 (en) 2009-10-15
CA2720824C (en) 2021-09-14
KR20170037682A (ko) 2017-04-04
US10357516B2 (en) 2019-07-23
BRPI0911176B1 (pt) 2019-10-15
EP3257375A1 (en) 2017-12-20
US20110286987A1 (en) 2011-11-24
HK1157140A1 (en) 2012-06-29
KR101742533B1 (ko) 2017-06-01
MX2010011018A (es) 2010-11-12
EP2285210B1 (en) 2017-05-17
CA2720824A1 (en) 2009-10-15
EP2285210A2 (en) 2011-02-23
US9713627B2 (en) 2017-07-25
AU2009233807B2 (en) 2014-11-27
IL208431A0 (en) 2010-12-30
US20180008639A1 (en) 2018-01-11
KR20110009134A (ko) 2011-01-27
SG189745A1 (en) 2013-05-31
JP2014231528A (ja) 2014-12-11
JP2011516570A (ja) 2011-05-26
ES2636563T3 (es) 2017-10-06
US20150157665A1 (en) 2015-06-11
KR101896430B1 (ko) 2018-09-10
JP5916383B2 (ja) 2016-05-11
US8900805B2 (en) 2014-12-02
BRPI0911176A2 (pt) 2015-07-28
ZA201006936B (en) 2016-03-30

Similar Documents

Publication Publication Date Title
BRPI0911176B8 (pt) método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea
EA201100125A1 (ru) Производные пирролопиридинилпиримидин-2-иламина
NI201100082A (es) Compuestos de isoindolina para uso en el tratamiento de cáncer.
EA201001456A1 (ru) Новые гетероциклические соединения и их применение
BRPI1015952B8 (pt) Método de introdução de uma nuclease sequência-específica (ssn) em uma célula vegetal
BR112013018352A2 (pt) composição de minociclina tópica e método
BRPI0613811B8 (pt) uso de células tronco estromais alogênicas derivadas de tecido adiposo
BR112013027307A2 (pt) método para tratar uma matriz de tecido; matriz de tecido acelular
MX2010009765A (es) Moleculas pequeñas que contienen boro como agentes anti-inflamatorios.
EA201791850A1 (ru) Борсодержащие малые молекулы
UA118248C2 (uk) Інгібітори глюкозилцерамідсинтази
BR112015007878A2 (pt) composto compreendendo oligonucleotídeo modificado, composição, combinação e uso dos mesmos
IN2015DN02938A (pt)
BRPI1011934A8 (pt) Composição
BR112013002811A2 (pt) meios básicos simplificados para cultura celular pluripotente de humano
EA201001698A1 (ru) Инсулиновые композиции сверхбыстрого действия
CU20120078A7 (es) Composiciones para tratar náusea y vómito centralmente mediados
BR112013031307A2 (pt) métodos para tratamento de material lignocelulósico
BR112012033548A2 (pt) métodos e composições para melhorar a mobilização de células-tronco
BR112013004700A2 (pt) método para prevenir ou tratar doenças ou distúrbios cardiovasculares
DK2252322T3 (da) Vaccinesammensætninger
CR11870A (es) Composiciones de perácido y 2-hidroxi ácido orgánico y métodos para tratar productos agrícolas
BR112012028711A2 (pt) métodos para a fabricação de uma emulsão de óleo em água, para a preparação de um kit de vacina e para redestilação de uma composição compreendendo 99% de esqualeno ou mais, assim como emulsão de óleo em água e kit
MX2014000515A (es) Metodo de tratamiento de inflamacion e himpertencion secuestrante de gama -cetoaldehido.
AR084652A1 (es) Glicoles como agentes inactivadores de patogenos

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/10/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/10/2019, OBSERVADAS AS CONDICOES LEGAIS

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/04/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF