WO2009048253A2 - Atopy cure baby dry milk with green tea and lactobacillus - Google Patents
Atopy cure baby dry milk with green tea and lactobacillus Download PDFInfo
- Publication number
- WO2009048253A2 WO2009048253A2 PCT/KR2008/005896 KR2008005896W WO2009048253A2 WO 2009048253 A2 WO2009048253 A2 WO 2009048253A2 KR 2008005896 W KR2008005896 W KR 2008005896W WO 2009048253 A2 WO2009048253 A2 WO 2009048253A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- green tea
- baby
- lactobacillus
- atopy
- dry milk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/16—Agglomerating or granulating milk powder; Making instant milk powder; Products obtained thereby
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/18—Milk in dried and compressed or semi-solid form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/40—Tea flavour; Tea oil; Flavouring of tea or tea extract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
Definitions
- This invention is the addition of a certain portion of green tea and lactobacillus to baby dry milk or weaning food for the cure and prevention of atopy.
- atopy treatment has been largely limited to symptomatic treatment that temporarily controls eruption and inflammation appearing on skin surface by applying steroid drugs and moisturizer to patients' skin.
- medicines or treatments that can fundamentally and easily cure atopy have not yet been invented for either babies or adults.
- a few oriental clinics practice treatment for atopy using their own herbal medicines, but their cure rate is very low. And they keep the composition secrete, require a long-term treatment of about 6 months.
- Some methods such as attaching green tea or aloes to patients' skin have different effects among every person and that is not established sure treatment.
- ⁇ i6> The inventor's previous applications include one case related with lactobacillus, and two cases related with green tea.
- this invention aims to provide babies with the baby dry milk and weaning food that can cure atopy and completely prevent atopy of normal babies who are given baby dry milk or weaning foods which can cause atopy easily, hoping to contribute to healthier society babies can be free from atopy.
- this invention features mixing 0.02 ⁇ 1.3 w/t wt % of green tea(on dry basis) in the product for the purpose of treatment and prevention of baby atopy. And when it comes to mixing green tea extract, green tea extract which is extracted from 0.02 ⁇ 1.3 w/t wt % of green tea(on dry basis) should be mixed in products.
- the adequate amount of green tea in baby dry milk or weaning food is 0.1 - 1.3 wt % in weight for treatment of baby atopy, and 0.02 - 0.1 wt % for prevention or aftercare of atopy.
- Manufacturing process of baby dry milk generally have follow steps. The first is raw material mixing followed by purification, sterilization, concentration, homogenization, drying, sieving, product mixing, nitrogen filling, and ,at last, packaging. And each of adequate amount of green tea, green tea powder, liquid or solid form of green tea extract and lactobacillus digestives (strains with intestinal regulation and digestion functions such as lactobacillus and butyric-acid bacteria and yeast fungi) should be measured and added into the above process where it should be.
- Atopy can be cured by adding only green tea without lactobacillus digestives, but if the content of green tea added is higher than 0.2 wt %, some useful intestinal bacterium would die or their intestinal activation can be impeded due to sterilizing function of green tea, which leads to green stool. Generally the higher concentration of green tea makes the thicker color of green stool. So it is much more recommendable to add lactobacillus digestives such as lactobacillus or butyric-acid bacteria, or yeast fungi to baby milk products along with green tea.
- ⁇ 50> The following is one of recommendable methods how to add in green tea and lactobacillus digestives such as lactobacillus during manufacturing process.
- Green tea or green tea extract can be added into baby dry milk or weaning food in any process of the above entire process, but green tea powder or solid form of green tea extract are recommended to be added into during the drying or packaging process. And, if possible, it is recommended to set a mixing process of green tea and lactobacillus digestives by installing a mixing tank before or after sieving process. In that case, the green tea powder or dry green tea extract to be added in during the mixing process is recommended to be sterilized in advance. If green tea extract or lactobacillus digestives to be added into is solid-form, it is recommended to add them in granular form or powdered form.
- Liquid green tea extract is recommended to be added in between the raw material mixing process and the drying process and higher concentration of green tea extract is recommended to be added in homogenization process after concentration, and lower concentration of green tea extract is recommended to be added in concentration process.
- Green tea powder can be added into in advance during the first half stage of the baby milk manufacturing process like the green tea leaves and leaves crushed in big size as shown in the above, and it can also be added into by setting a green tea mixing process before or after the sieving process in the second half stage of baby milk manufacturing process. If green tea powder is added into in the second half of the process like this, atopy is cured due to the effects of green tra itself, while if it is added into in the first half, green tea ingredients extracted into hot milk during manufacturing process remains in baby dry milk through concentration and drying.
- the choice of putting in green tea powder during the first half can require another process of filtering green tea powder, or let the green tea powder remain in baby dry milk to the last of manufacturing process. In this case, it is recommended to set another process of filtering green tea powder in the first half of the entire milk powder manufacturing process.
- the general manufacturing process of baby weaning food is made up of mixing of raw materials such as baby dry milk, followed by drying, crushing, mixing, granulation, fraction, filling, and packaging. So, in this case it is recommended to add into green tea powder and dried lactobaci llus in the mixing process. In the meantime, it is also possible to add dried green tea leaves during raw material crushing so that green tea leaves can be crushed with other raw materials.
- Green tea powder or fine pieces of green tea leaves are in general made using crushing or grinding device.
- Crushing device is based on pressing or hitting mechanism with the pressing used for rough grinding and the hitting for both rough and fine grinding.
- Typical crushing devices are jaw crusher, hammer crusher, cutter, etc.
- Dried green tea leaves are easily broken with just a light pressing or hitting, which enables us to easily obtain small particles less than a few millimeters in diameter.
- Green tea powder production can have grinding process after crushing process, or can only have grinding process.
- These grinding machines can generally produce green tea powder particles of 1 to 100 ⁇ m in diameter with average diameter being 10 to 50 ⁇ m. This size of diameter of particles are adequate for applying the invention.
- the diameter of passed particles becomes 254 ⁇ m with 25.4 mm divided by 100, but in reality only around 150 ⁇ m assuming the thickness of mesh is 100 ⁇ m.
- Liquid or solid green tea extract can be obtained using solvents such as water and edible ethyl alcohol (ethanol) to extract green tea ingredients, which is used as it is, or concentrated, or dried after concentration. If water is used to extract green tea ingredients, the water is recommended to be first boiled to remove air and dissolved oxygen in it. If green tea is put in this hot water, you can reduce browning of the extract and extract most of useful ingredients in the green tea leaves.
- solvents such as water and edible ethyl alcohol (ethanol) to extract green tea ingredients, which is used as it is, or concentrated, or dried after concentration. If water is used to extract green tea ingredients, the water is recommended to be first boiled to remove air and dissolved oxygen in it. If green tea is put in this hot water, you can reduce browning of the extract and extract most of useful ingredients in the green tea leaves.
- Ethanol can be divided into edible and non-edible (for industrial use). Of course it is recommended to use edible ethanol when extracting green tea ingredients. Purified water, edible ethanol, or mixture of the two can be used as a solvent to extract green tea ingredients.
- the green tea extract produced in this manner can be used in a form of concentration, which requires atmospheric or vacuum distillation.
- fermented ethyl alcohol can be added to purified water for more effective soak out.
- Fermented ethyl alcohol is more expensive than water, but alcohol can be recycled after distilling the alcohol during distillation process.
- ethyl alcohol as the amount of the alcohol increases, green tea ingredients can be extracted more easily even at low temperature.
- fermented alcohol is largely composed of ethanol (more than 95 wt 0 Io) , but may contain a small amount of methanol, which is toxic substance harmful to health (* standard quality of fermented alcohol ' ⁇ methanol content of 0.5 rag/m£ or less), it is recommended to extract green tea elements at a temperature lower than the boiling point of ethanol and higher than that of methanol if fermented alcohol is used.
- the extract is concentrated by heating at higher than the boiling point of water (it is 100 °C in case of 1 atmospheric pressure condition), if necessary.
- Vacuum distillation enables energy saving due to easier distillation even at a lower temperature.
- Solid form of green tea extract can be obtained by first concentrating the green tea extract obtained in the above, and secondly going through heating and drying process at atmospheric or vacuum pressure or a vacuum drying process, or a reduced pressure freeze-drying process, or a vacuum freeze-drying process.
- ⁇ i3i> A 5-month-old baby weighing 5.2 kg received treatment with a 0.1 wt % concentration of green tea powder for 2 weeks, which stopped without any sign of improvement seen.
- ⁇ i4i> A 14-year-old teen improved significantly in health after receiving treatment with green tea leaves on the basis of 0.3g/day for 2 weeks.
- a 6-month-old baby weighing 8 kg showed no improvement with a 0.03 wt % concentration of green tea extract.
- the symptom improved after receiving treatment with 0.15 wt % concentration of green tea extract for around 2 weeks, but deteriorated when changing baby dry milk.
- This baby was cured after receiving treatment with an increased green tea extract concentration of 0.3 wt % for around 3 days.
- ⁇ i73> 0.8 wt % of concentration brought greater curative effects.
- the baby's intake of green tea did not result in any improvement in atopy while the baby was suffering from a fever.
- the baby's health improved again when green tea powder with 1.0 - 1.3 wt % concentration was fed.
- the total amount of lactobacillus digestives fed reached 5 wt % or less of the baby dry milk on dry weight basis.
- the lactobacillus digestives used had in it 25 mg pure lactobacilli/g, 5 mg pure butyric acid bacteria/g, 50 mg pure dried yeast/g, and 3 mg pure activated digestive bacteria/g.
- lactobacillus digestive had 8.3wt % of pure lactobacillus content rate so that 1.5 ⁇ 3wt % of the lactobacillus digestive is equal to 0.12 ⁇ 0.25wt % of lactobacillus on pure lactobacillus basis.
- baby dry milk or weaning food needs 0.1 - 1.3 wt % of green tea concentration in order to treat atopy, and 0.02 - 0.1 wt % of green tea concentration in order to prevent atopy. If you feed a baby with 0.15 - 10 wt % (about 0.01 - 0.8 wt % purely on lactobacillus basis) of lactobacillus digestives containing lactobacillus, butyric-acid bacteria or yeast fungi along with the baby dry milk or weaning food, you can prevent green stool which is a side effect of green tea and improve digestive function of a baby.
- Lactobacilli are as follows ; Reuteri, Lactobacillus, Bifidobacterium, Streptococcus, Leuconostoc, Pediococcus, Lactococcus, Lactobacillus Bulgaricus, Lactobacillus Casei , Lactobacillus acidophilus, Streptococcus Thermophi lus.
- Lactobacillus, butyric-acid bacteria or yeast fungi help prevent green stool caused by green tea and help improve digestive function so that you can expect much better efficacy when those lactobacillus digestives are used in conjunction with green tea.
- the concentration of green tea needed for prevention of atopy is at least 0.02 wt %, which is equal to one tenth of 0.2 wt %, the green tea concentration that causes green stool. So, applying the same proportion to get the adequate amount of the concentration of lactobacillus digestive needed, we need at least more than 0.15 wt % (0.01 wt % on pure lactobacillus basis ) of lactobacillus digestive. And the upper limit for the concentration of green tea is 1.3 wt %, which is 6.5 times more than the 0.2wt %. So applying the same proportion, we can know the upper limit for lactobacillus digestive concentration is 9.75 wt % ( 0.8 wt % on pure lactobacillus basis ). That is why we decided the upper limit was 10 wt %.
- First method is a natural method to grow the leaves in the most similar environment to wild life, keeping as far from using agrichemicals as possible.
- Second is a Government-certified organic method not to use agrichemicals or synthesized fertilizers while using some natural fertilizers.
- Third is a general method to use both of agrichemicals and synthesized fertilizers.
- ⁇ 390> The causes and seriousness of atopy could vary among babies. So it is recommendable to diversify into more than 3 steps of products according to the concentration of green tea within range of 0.1 ⁇ 1.3wt % in case of products for atopycure. And for the purpose of prevention or aftercare of atopy, it is recommendable to diversify into more than 2 steps of products according to the concentration of green tea within range of 0.02 ⁇ O.lwt % too.
- ⁇ 395> Aside from the prevention and treatment of atopy, we can expect a lot of other advantageous effects from this invention. It includes: babies' emotional stability, improvement of babies' brain, prevention of children fatness, decline in blood fat and cholesterol, prevention of the proliferation of poisonous bacterium that could occur after opening of baby dry milk or weaning food, prevention of food poisoning and cancer, prevention of side effects caused by synthesized additive to baby dry milk or weaning food, prevention of decayed tooth, detoxication of various kinds of harmful substances that could be included for example cow's food originated substance, during manufacturing process.
- 0.05wt % of green tea concentration with content of lactobacillus digestive being 0.03wt % (on pure lactobacillus basis) is adequate for prevention of atopy
- O.lwt % of green tea concentration with content of lactobacillus digestive being 0.05wt %(on pure lactobacillus basis) is adequate for aftercare.
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
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- Mycology (AREA)
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- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
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- Alternative & Traditional Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dairy Products (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
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Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1005529A GB2465939A (en) | 2007-10-10 | 2008-10-08 | Atopy cure baby dry milk with green tea and lactobacillus |
| JP2010528798A JP2011500016A (ja) | 2007-10-10 | 2008-10-08 | 緑茶及び乳酸菌を含む、アトピー治療用乳児用粉乳 |
| CN200880111228A CN101820768A (zh) | 2007-10-10 | 2008-10-08 | 具有绿茶和乳杆菌的特应性治愈婴儿奶粉 |
| AU2008311541A AU2008311541B2 (en) | 2007-10-10 | 2008-10-08 | Atopy cure baby dry milk with green tea and lactobacillus |
| US12/680,802 US20100215627A1 (en) | 2007-10-10 | 2008-10-08 | Atopy cure baby dry milk with green tea and lactobacillus |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2007-0103324 | 2007-10-10 | ||
| KR1020070103324A KR100930996B1 (ko) | 2007-10-10 | 2007-10-10 | 녹차와 유산균이 함유된 아토피 치료용 분유와 이유식 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| WO2009048253A2 true WO2009048253A2 (en) | 2009-04-16 |
| WO2009048253A3 WO2009048253A3 (en) | 2009-06-18 |
| WO2009048253A4 WO2009048253A4 (en) | 2009-08-27 |
Family
ID=39881980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/KR2008/005896 Ceased WO2009048253A2 (en) | 2007-10-10 | 2008-10-08 | Atopy cure baby dry milk with green tea and lactobacillus |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100215627A1 (enExample) |
| JP (1) | JP2011500016A (enExample) |
| KR (1) | KR100930996B1 (enExample) |
| CN (1) | CN101820768A (enExample) |
| AU (1) | AU2008311541B2 (enExample) |
| GB (1) | GB2465939A (enExample) |
| WO (1) | WO2009048253A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2010001124A1 (es) * | 2010-10-14 | 2011-01-21 | Univ De Concepcion 50% Ma Loreto Ormeno 50% | Alimento funcional probiotico que comprende cepas viables de lactobacillus sp.; uso de dicho alimento funcional para contrarestar los efectos colaterales de la quimioterapia. |
| KR101252249B1 (ko) * | 2011-06-13 | 2013-04-08 | 서범구 | 선옥균을 이용한 식품첨가용 발효 조성물과 그 제조방법 |
| KR101660764B1 (ko) * | 2015-02-06 | 2016-10-05 | 인지전기공업 주식회사 | 베타글루칸 이유식 제조방법 및 이에 의해 제조된 베타글루칸 이유식 |
| KR101655042B1 (ko) | 2015-08-24 | 2016-09-07 | 영남대학교 산학협력단 | 모유 또는 분유의 기능 또는 품질 평가 방법 |
| KR101655048B1 (ko) | 2015-11-26 | 2016-09-06 | 영남대학교 산학협력단 | 트랜스지방에 노출된 모유의 품질 평가 방법 |
| DK3547841T3 (da) * | 2016-12-02 | 2021-02-08 | Fairlife Llc | Lactosefrit mælkepulver, der ikke brunfarves, og fremgangsmåder til fremstilling deraf |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4010062B2 (ja) * | 1998-09-02 | 2007-11-21 | 医療法人社団青藍会 | アトピー性皮膚炎を防ぐ保健食品 |
| CA2298349C (en) * | 1999-02-16 | 2008-11-18 | Sunstar Inc. | Antiallergic composition and antipruritic composition |
| JP3958924B2 (ja) * | 2000-10-11 | 2007-08-15 | 有限会社お菓子のピエロ | 離乳食及びその製造方法 |
| JP4712289B2 (ja) * | 2003-08-26 | 2011-06-29 | 株式会社エイ・エル・エイ | 免疫促進用組成物 |
| JP2006143677A (ja) * | 2004-11-22 | 2006-06-08 | Ace Bio Product Kk | アレルギー抑制物質 |
| JP5273695B2 (ja) * | 2005-03-03 | 2013-08-28 | 株式会社明治 | ビフィズス菌を有効成分とするアレルギー予防および/または治療剤 |
| KR20060093686A (ko) * | 2006-07-20 | 2006-08-25 | 임수현 | 녹차분유 |
| JP5601753B2 (ja) * | 2007-06-18 | 2014-10-08 | アサヒ飲料株式会社 | 茶入り発酵飲食品及びその製造方法 |
-
2007
- 2007-10-10 KR KR1020070103324A patent/KR100930996B1/ko not_active Expired - Fee Related
-
2008
- 2008-10-08 CN CN200880111228A patent/CN101820768A/zh active Pending
- 2008-10-08 AU AU2008311541A patent/AU2008311541B2/en not_active Ceased
- 2008-10-08 GB GB1005529A patent/GB2465939A/en not_active Withdrawn
- 2008-10-08 JP JP2010528798A patent/JP2011500016A/ja active Pending
- 2008-10-08 WO PCT/KR2008/005896 patent/WO2009048253A2/en not_active Ceased
- 2008-10-08 US US12/680,802 patent/US20100215627A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008311541B2 (en) | 2010-12-16 |
| WO2009048253A3 (en) | 2009-06-18 |
| US20100215627A1 (en) | 2010-08-26 |
| KR20080071056A (ko) | 2008-08-01 |
| KR100930996B1 (ko) | 2009-12-11 |
| GB2465939A (en) | 2010-06-09 |
| AU2008311541A1 (en) | 2009-04-16 |
| WO2009048253A4 (en) | 2009-08-27 |
| JP2011500016A (ja) | 2011-01-06 |
| GB201005529D0 (en) | 2010-05-19 |
| CN101820768A (zh) | 2010-09-01 |
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