WO2009004999A8 - シームレスカプセル - Google Patents
シームレスカプセル Download PDFInfo
- Publication number
- WO2009004999A8 WO2009004999A8 PCT/JP2008/061721 JP2008061721W WO2009004999A8 WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8 JP 2008061721 W JP2008061721 W JP 2008061721W WO 2009004999 A8 WO2009004999 A8 WO 2009004999A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- seamless capsule
- interfacial tension
- tension regulator
- gelation accelerator
- capsule
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08790686.3A EP2172225B1 (en) | 2007-06-29 | 2008-06-27 | Seamless capsule |
JP2009521608A JP5047285B2 (ja) | 2007-06-29 | 2008-06-27 | シームレスカプセル |
ES08790686T ES2748934T3 (es) | 2007-06-29 | 2008-06-27 | Cápsula sin costura |
US12/452,374 US20100119598A1 (en) | 2007-06-29 | 2008-06-27 | Seamless capsule |
NZ582576A NZ582576A (en) | 2007-06-29 | 2008-06-27 | Seamless capsule comprising gelatin and a plasticizer |
CN2008801051658A CN101801416B (zh) | 2007-06-29 | 2008-06-27 | 无缝胶囊 |
AU2008272135A AU2008272135B2 (en) | 2007-06-29 | 2008-06-27 | Seamless capsule |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007173198 | 2007-06-29 | ||
JP2007-173198 | 2007-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009004999A1 WO2009004999A1 (ja) | 2009-01-08 |
WO2009004999A8 true WO2009004999A8 (ja) | 2009-04-09 |
Family
ID=40226045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/061721 WO2009004999A1 (ja) | 2007-06-29 | 2008-06-27 | シームレスカプセル |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100119598A1 (ja) |
EP (1) | EP2172225B1 (ja) |
JP (1) | JP5047285B2 (ja) |
KR (1) | KR20100039362A (ja) |
CN (2) | CN102552213A (ja) |
AU (1) | AU2008272135B2 (ja) |
ES (1) | ES2748934T3 (ja) |
MY (1) | MY157882A (ja) |
NZ (1) | NZ582576A (ja) |
TW (1) | TW200911358A (ja) |
WO (1) | WO2009004999A1 (ja) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ600720A (en) * | 2008-01-10 | 2012-12-21 | Takeda Pharmaceutical | A Seamless Capsule For A Liquid Pharmaceutical Composition |
EP4137128A1 (en) | 2008-09-02 | 2023-02-22 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and a statin, and methods of using same |
PT2395991E (pt) | 2009-02-10 | 2013-09-03 | Amarin Pharmaceuticals Ie Ltd | Utilização de éster etílico de ácido eicosapentaenóico para tratamento de hipertrigliceridemia |
EP3791880A1 (en) | 2009-04-29 | 2021-03-17 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical compositions comprising epa |
LT3278665T (lt) | 2009-04-29 | 2020-12-10 | Amarin Pharmaceuticals Ireland Limited | Stabili farmacinė kompozicija ir jos panaudojimo būdai |
ES2856959T3 (es) | 2009-06-15 | 2021-09-28 | Amarin Pharmaceuticals Ie Ltd | Composiciones y métodos para el tratamiento del ictus en un sujeto en terapia simultánea con estatina |
JP5421674B2 (ja) * | 2009-07-01 | 2014-02-19 | 株式会社ファンケル | ソフトカプセル用乳化組成物及びソフトカプセル剤 |
RU2012116079A (ru) | 2009-09-23 | 2013-10-27 | АМАРИН КОРПОРЕЙШН ПиЭлСи | Фармацевтическая композиция, включающая омега-3 жирную кислоту и гидроксипроизводное статина и способы ее применения |
US20140127289A1 (en) | 2010-11-29 | 2014-05-08 | Armarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
JP5876695B2 (ja) * | 2011-09-29 | 2016-03-02 | 森下仁丹株式会社 | シームレスカプセルおよびその製造方法 |
US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
US20130131170A1 (en) | 2011-11-07 | 2013-05-23 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
EP2800469B1 (en) | 2012-01-06 | 2021-08-25 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering levels of high-sensitivity (hs-crp) in a subject |
DK3363433T3 (da) | 2012-06-29 | 2021-03-08 | Amarin Pharmaceuticals Ie Ltd | Fremgangsmåder til reduktion af risikoen for en kardiovaskulær begivenhed i et individ i statinbehandling ved anvendelse af eicosapentaensyreetylester |
US20150265566A1 (en) | 2012-11-06 | 2015-09-24 | Amarin Pharmaceuticals Ireland Limited | Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy |
US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
US9814733B2 (en) | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
US9624492B2 (en) | 2013-02-13 | 2017-04-18 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof |
US9662307B2 (en) | 2013-02-19 | 2017-05-30 | The Regents Of The University Of Colorado | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof |
US9283201B2 (en) | 2013-03-14 | 2016-03-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating or preventing obesity in a subject in need thereof |
US20140271841A1 (en) | 2013-03-15 | 2014-09-18 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin |
WO2014170947A1 (ja) | 2013-04-15 | 2014-10-23 | 三生医薬株式会社 | 崩壊可能なカプセル及びその製造方法並びに喫煙器具 |
US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
US20150065572A1 (en) | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
US9585859B2 (en) | 2013-10-10 | 2017-03-07 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy |
MX369410B (es) * | 2014-01-31 | 2019-11-07 | Morishita Jintan Co | Agente de administración oral para rumiantes y alimento para rumiantes que lo contiene. |
US10561631B2 (en) | 2014-06-11 | 2020-02-18 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing RLP-C |
US10172818B2 (en) | 2014-06-16 | 2019-01-08 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
US10406130B2 (en) | 2016-03-15 | 2019-09-10 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
JP6884369B2 (ja) * | 2016-12-28 | 2021-06-09 | 三生医薬株式会社 | シームレスカプセル |
US10966951B2 (en) | 2017-05-19 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject having reduced kidney function |
US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
PT4056176T (pt) | 2018-09-24 | 2024-05-27 | Amarin Pharmaceuticals Ie Ltd | Métodos de redução do risco de eventos cardiovasculares num indivíduo |
JP6603817B1 (ja) | 2019-01-18 | 2019-11-06 | 三生医薬株式会社 | シ−ムレスカプセルならびにこれを含むフィルターおよび喫煙器具 |
KR20200105068A (ko) | 2019-02-28 | 2020-09-07 | 우석대학교 산학협력단 | 오일을 함유하는 심리스 캡슐의 제조방법 |
KR102204696B1 (ko) * | 2019-12-10 | 2021-01-19 | 한국 한의학 연구원 | 1-모노에이코사펜타에노인을 유효성분으로 함유하는 주름개선용 조성물 |
CN115361940A (zh) | 2020-03-30 | 2022-11-18 | 三生医药株式会社 | 含有薄荷醇的组合物 |
US20230372262A1 (en) | 2020-11-06 | 2023-11-23 | Kinki University | Composition for treating vascular disease, composition for reventing vascular disease, composition for treating hypertension, and composition for preventing hypertension |
JP6913976B1 (ja) * | 2020-11-13 | 2021-08-04 | 東洋カプセル株式会社 | シームレスカプセル及びその製造方法 |
KR20240012390A (ko) | 2021-04-21 | 2024-01-29 | 애머린 파마슈티칼스 아일랜드 리미티드 | 심부전의 위험을 감소시키는 방법 |
KR20240069709A (ko) | 2021-09-14 | 2024-05-20 | 산쇼 이야쿠 가부시키가이샤 | 카리오필렌 함유 조성물 |
TW202327557A (zh) | 2021-09-14 | 2023-07-16 | 日商三生醫藥股份有限公司 | 含丁香烴之組合物 |
KR20230151363A (ko) | 2022-04-25 | 2023-11-01 | 유엠에스엔지니어링 주식회사 | 오메가 3 심리스 연질캡슐 제조방법 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8819110D0 (en) | 1988-08-11 | 1988-09-14 | Norsk Hydro As | Antihypertensive drug & method for production |
JP2806564B2 (ja) * | 1989-07-20 | 1998-09-30 | 森下仁丹株式会社 | 親水性物質を内容物とするシームレスカプセルおよびその製法 |
JPH0412083A (ja) * | 1990-04-27 | 1992-01-16 | Osaka Titanium Co Ltd | シリコン単結晶製造方法 |
JP3159724B2 (ja) | 1991-04-19 | 2001-04-23 | フロイント産業株式会社 | シームレスカプセル製造方法および装置 |
JPH0826976A (ja) * | 1994-07-21 | 1996-01-30 | Freunt Ind Co Ltd | 食品状医薬品 |
US5650232A (en) * | 1994-10-07 | 1997-07-22 | Warner-Lambert Company | Method for making seamless capsules |
JP3759986B2 (ja) * | 1995-12-07 | 2006-03-29 | フロイント産業株式会社 | シームレスカプセルおよびその製造方法 |
ATE305810T1 (de) * | 2000-05-22 | 2005-10-15 | Pro Aparts Investimentos E Con | Fettsäure enthaltende pharmazeutische zusammensetzung die wenigstens 80 gew. epa und dha enthält |
EP1709958A1 (de) * | 2002-12-05 | 2006-10-11 | Symrise GmbH & Co. KG | Nahtlose gefüllte Kapseln |
WO2004056370A1 (en) * | 2002-12-20 | 2004-07-08 | Pronova Biocare As | Use of a fatty acid composition for treatment of male infertility |
JP2004262774A (ja) * | 2003-02-20 | 2004-09-24 | Freunt Ind Co Ltd | シームレスカプセル |
GB0403247D0 (en) * | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
US20060110442A1 (en) * | 2004-02-17 | 2006-05-25 | Jochen Wonschik | Coated sherical seamless filled capsules |
WO2008012329A2 (en) * | 2006-07-28 | 2008-01-31 | V. Mane Fils | Seamless capsules containing high amounts of polyunsaturated fatty acids and a flavouring component |
-
2008
- 2008-06-27 NZ NZ582576A patent/NZ582576A/en not_active IP Right Cessation
- 2008-06-27 US US12/452,374 patent/US20100119598A1/en not_active Abandoned
- 2008-06-27 MY MYPI20095565A patent/MY157882A/en unknown
- 2008-06-27 ES ES08790686T patent/ES2748934T3/es active Active
- 2008-06-27 EP EP08790686.3A patent/EP2172225B1/en active Active
- 2008-06-27 CN CN2012100746751A patent/CN102552213A/zh active Pending
- 2008-06-27 KR KR1020107001925A patent/KR20100039362A/ko not_active Application Discontinuation
- 2008-06-27 CN CN2008801051658A patent/CN101801416B/zh not_active Expired - Fee Related
- 2008-06-27 TW TW097124053A patent/TW200911358A/zh unknown
- 2008-06-27 JP JP2009521608A patent/JP5047285B2/ja active Active
- 2008-06-27 WO PCT/JP2008/061721 patent/WO2009004999A1/ja active Application Filing
- 2008-06-27 AU AU2008272135A patent/AU2008272135B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW200911358A (en) | 2009-03-16 |
EP2172225A4 (en) | 2011-04-27 |
EP2172225B1 (en) | 2019-08-07 |
CN102552213A (zh) | 2012-07-11 |
JP5047285B2 (ja) | 2012-10-10 |
JPWO2009004999A1 (ja) | 2010-08-26 |
KR20100039362A (ko) | 2010-04-15 |
US20100119598A1 (en) | 2010-05-13 |
EP2172225A1 (en) | 2010-04-07 |
WO2009004999A1 (ja) | 2009-01-08 |
ES2748934T3 (es) | 2020-03-18 |
CN101801416A (zh) | 2010-08-11 |
NZ582576A (en) | 2012-05-25 |
AU2008272135A1 (en) | 2009-01-08 |
AU2008272135B2 (en) | 2013-10-31 |
MY157882A (en) | 2016-07-29 |
EP2172225A8 (en) | 2011-06-29 |
CN101801416B (zh) | 2012-10-24 |
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