WO2009001869A1 - 幼若白血球の分析用試薬及び分析用試薬キット - Google Patents

幼若白血球の分析用試薬及び分析用試薬キット Download PDF

Info

Publication number
WO2009001869A1
WO2009001869A1 PCT/JP2008/061573 JP2008061573W WO2009001869A1 WO 2009001869 A1 WO2009001869 A1 WO 2009001869A1 JP 2008061573 W JP2008061573 W JP 2008061573W WO 2009001869 A1 WO2009001869 A1 WO 2009001869A1
Authority
WO
WIPO (PCT)
Prior art keywords
reagent
leukocyte
primitive
analysis
kit
Prior art date
Application number
PCT/JP2008/061573
Other languages
English (en)
French (fr)
Inventor
Yukiko Kataoka
Tomohiro Tsuji
Shinichiro Oguni
Ayumu Yoshida
Masaki Abe
Original Assignee
Sysmex Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corporation filed Critical Sysmex Corporation
Priority to CN2008800206079A priority Critical patent/CN101680878B/zh
Priority to JP2009520621A priority patent/JP5214603B2/ja
Priority to US12/666,770 priority patent/US8859200B2/en
Priority to EP08777589A priority patent/EP2166354B1/en
Publication of WO2009001869A1 publication Critical patent/WO2009001869A1/ja
Priority to US13/956,939 priority patent/US9222934B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

　本発明は、赤血球及び成熟白血球の細胞膜に損傷を与える界面活性剤と、損傷した血球を収縮させる可溶化剤と、式（Ｉ）で示される色素及び式（ＩＩ）で示される色素（式（Ｉ）及び（ＩＩ）において、Ｘ-は、アニオンである）から選択される少なくとも１種の核酸染色色素とを含む幼若白血球の分析用試薬を提供する。
PCT/JP2008/061573 2007-06-25 2008-06-25 幼若白血球の分析用試薬及び分析用試薬キット WO2009001869A1 (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN2008800206079A CN101680878B (zh) 2007-06-25 2008-06-25 幼稚白细胞分析用试剂及分析用试剂盒
JP2009520621A JP5214603B2 (ja) 2007-06-25 2008-06-25 幼若白血球の分析用試薬及び分析用試薬キット
US12/666,770 US8859200B2 (en) 2007-06-25 2008-06-25 Reagent and reagent kit for analysis of immature leukocyte
EP08777589A EP2166354B1 (en) 2007-06-25 2008-06-25 Reagent and reagent kit for analysis of primitive leukocyte
US13/956,939 US9222934B2 (en) 2007-06-25 2013-08-01 Reagent and reagent kit for analysis of immature leukocyte

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007166639 2007-06-25
JP2007-166639 2007-06-25

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/666,770 A-371-Of-International US8859200B2 (en) 2007-06-25 2008-06-25 Reagent and reagent kit for analysis of immature leukocyte
US13/956,939 Continuation US9222934B2 (en) 2007-06-25 2013-08-01 Reagent and reagent kit for analysis of immature leukocyte

Publications (1)

Publication Number Publication Date
WO2009001869A1 true WO2009001869A1 (ja) 2008-12-31

Family

ID=40185681

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/061573 WO2009001869A1 (ja) 2007-06-25 2008-06-25 幼若白血球の分析用試薬及び分析用試薬キット

Country Status (5)

Country Link
US (2) US8859200B2 (ja)
EP (1) EP2166354B1 (ja)
JP (1) JP5214603B2 (ja)
CN (1) CN101680878B (ja)
WO (1) WO2009001869A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507068A (ja) * 2017-08-24 2020-03-05 コーリア リサーチ インスティテュート オブ ケミカル テクノロジー 生体組織サイズを調整するための組成物、及び前記組成物を使用して生体組織のサイズを調整する方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101349644B (zh) * 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
CN101475754A (zh) 2008-01-04 2009-07-08 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料,组合物及在生物样品染色中的用途
CN101726579B (zh) * 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
CN101750274B (zh) * 2008-12-17 2014-06-25 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法
US8794971B2 (en) * 2010-10-09 2014-08-05 Yellowpages.Com Llc Method and system for assigning a task to be processed by a crowdsourcing platform
EP2607899B1 (en) * 2011-12-21 2016-08-10 Beckman Coulter, Inc. Method for labeling intracellular and extracellular targets of leukocytes

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06273413A (ja) * 1993-03-19 1994-09-30 Toa Medical Electronics Co Ltd 幼若細胞測定用試薬
JPH10206423A (ja) * 1996-11-20 1998-08-07 Toa Medical Electronics Co Ltd 幼若白血球の分類計数法
JP2002223791A (ja) * 2000-11-08 2002-08-13 Sysmex Corp 骨髄有核細胞の分類計数方法
JP2003329668A (ja) * 2002-05-16 2003-11-19 Sysmex Corp 骨髄液有核細胞自動分析方法
WO2004001408A1 (ja) * 2002-06-24 2003-12-31 Sysmex Corporation 白血球の分類計数方法
JP2006091024A (ja) * 2005-10-28 2006-04-06 Sysmex Corp 白血球分類計数方法及び白血球分類計数試薬キット

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2935529B2 (ja) 1990-03-01 1999-08-16 シスメックス株式会社 白血球分類方法および試薬
US5389549A (en) * 1987-05-29 1995-02-14 Toa Medical Electronics Co., Ltd. Method for classifying leukocytes and a reagent used therefor
JPH07113632B2 (ja) 1991-04-22 1995-12-06 株式会社日立製作所 白血球分析方法
JP3048260B2 (ja) 1991-07-29 2000-06-05 シスメックス株式会社 白血球分類計数用試料調製方法
JP3886271B2 (ja) * 1998-11-27 2007-02-28 シスメックス株式会社 赤芽球の分類計数用試薬及び分類計数方法
US6368864B1 (en) * 2000-05-05 2002-04-09 Coulter International Corp. Dyes and methods of reticulocyte enumeration
US7049093B2 (en) * 2000-11-08 2006-05-23 Sysmex Corporation Method of classifying and counting nucleated bone marrow cells
JP2002207036A (ja) 2001-01-10 2002-07-26 Sysmex Corp 白血球腫瘍細胞検出方法
US6869798B2 (en) * 2003-04-17 2005-03-22 Clinical Diagnostics Solutions, Inc. Lytic reagent composition for leukocyte differential analysis
US7625757B2 (en) * 2006-01-27 2009-12-01 Sysmex Corporation Reagent for immature leukocyte analysis and reagent kit
JP4976038B2 (ja) * 2006-03-29 2012-07-18 シスメックス株式会社 血液学的試料の測定方法
JP4338206B2 (ja) 2006-04-23 2009-10-07 シスメックス株式会社 赤芽球の分類計数方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06273413A (ja) * 1993-03-19 1994-09-30 Toa Medical Electronics Co Ltd 幼若細胞測定用試薬
JPH10206423A (ja) * 1996-11-20 1998-08-07 Toa Medical Electronics Co Ltd 幼若白血球の分類計数法
JP2002223791A (ja) * 2000-11-08 2002-08-13 Sysmex Corp 骨髄有核細胞の分類計数方法
JP2003329668A (ja) * 2002-05-16 2003-11-19 Sysmex Corp 骨髄液有核細胞自動分析方法
WO2004001408A1 (ja) * 2002-06-24 2003-12-31 Sysmex Corporation 白血球の分類計数方法
JP2006091024A (ja) * 2005-10-28 2006-04-06 Sysmex Corp 白血球分類計数方法及び白血球分類計数試薬キット

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2166354A4 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507068A (ja) * 2017-08-24 2020-03-05 コーリア リサーチ インスティテュート オブ ケミカル テクノロジー 生体組織サイズを調整するための組成物、及び前記組成物を使用して生体組織のサイズを調整する方法
US11168108B2 (en) 2017-08-24 2021-11-09 Korea Research Institute Of Chemical Technology Composition for adjusting biological tissue size, and method for adjusting size of biological tissue using said composition

Also Published As

Publication number Publication date
CN101680878A (zh) 2010-03-24
EP2166354B1 (en) 2012-11-07
EP2166354A1 (en) 2010-03-24
JP5214603B2 (ja) 2013-06-19
US8859200B2 (en) 2014-10-14
JPWO2009001869A1 (ja) 2010-08-26
CN101680878B (zh) 2013-07-31
US9222934B2 (en) 2015-12-29
EP2166354A4 (en) 2010-06-30
US20140038179A1 (en) 2014-02-06
US20100178654A1 (en) 2010-07-15

Similar Documents

Publication Publication Date Title
WO2009001868A1 (ja) 幼若白血球の分析用試薬及び分析用試薬キット
WO2009001869A1 (ja) 幼若白血球の分析用試薬及び分析用試薬キット
ATE551401T1 (de) Reagens zum nachweis eines analyten
WO2010039627A3 (en) Biodetection articles
WO2006089091A3 (en) Methods for detecting minimum residual disease
WO2007062090A8 (en) Methods and compositions related to b cell assays
NO20075379L (no) Fremgangsmate ved vedlikehold av en bronn med bronnvaeske omfattende et elastisk materiale.
WO2009056340A3 (de) Vorrichtung zum nachweis von bestandteilen in einem fluid
DK1819366T3 (da) Bejdsesammensætning til bejdsning af en ophthalmisk membran
ATE485331T1 (de) Thiolselektive wasserlösliche polymerderivate
WO2009013884A1 (ja) 鉛濃度測定用試薬及び鉛濃度測定方法
WO2005005977A3 (en) Fluorescent phospholipase assays and compositions
ATE401863T1 (de) Neue viskoelastische zusammensetzung umfassend alginat und vitamin e tpgs oder tpgsa
TW200709043A (en) Method for performing subroutine return operation and processor-readable storage medium
WO2005117277A3 (en) Selecting common features of accessories coupled to a communications device
WO2006046979A3 (en) Feline infectious peritonitis (fip) and systemic multi-organ coronavirus biomarkers and screening methods
WO2004094992A3 (en) Methods for analysis of biological dataset profiles
WO2014023984A3 (en) Method for the direct detection of mycobacterium tuberculosis
WO2005033656A3 (en) Method for identifying objects to be used in an automatic clinical analyzer
WO2003067978A3 (en) Biological fluid stabilizing composition and method of use thereof
WO2010133881A3 (en) Tissue analysis
WO2005026911A3 (en) Apparatus and method for identifying therapeutic targets using a computer model
AU2003300109A1 (en) Rapid test for antibodies against hiv in urine
WO2008093329A3 (en) Kit and methods for detection of pathogens, such as strep antigens, in a body sample
BRPI0417037A (pt) métodos de classificação de toxicidade retiniana

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200880020607.9

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08777589

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009520621

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 12666770

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008777589

Country of ref document: EP