WO2005020937A1 - 歯牙塗布用組成物 - Google Patents
歯牙塗布用組成物 Download PDFInfo
- Publication number
- WO2005020937A1 WO2005020937A1 PCT/JP2004/012698 JP2004012698W WO2005020937A1 WO 2005020937 A1 WO2005020937 A1 WO 2005020937A1 JP 2004012698 W JP2004012698 W JP 2004012698W WO 2005020937 A1 WO2005020937 A1 WO 2005020937A1
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- WO
- WIPO (PCT)
- Prior art keywords
- tooth
- composition
- coating composition
- sodium
- tooth coating
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Definitions
- the present invention relates to a tooth coating agent which is applied to a tooth to enhance the health or cosmetic effect of the tooth, or an adhesive for adhering a seal, crushed stone, a glittering agent, etc. to the tooth for the purpose of art, or
- the present invention relates to a tooth coating composition which can be used for a tooth paint for coloring teeth for the purpose of coating. Background art
- tooth coating compositions have been developed and marketed for the purpose of improving the cosmetic and health of teeth.
- These tooth coating compositions include safety to the human body, dispersibility of pigments, hiding power for covering darkened parts of teeth, aesthetics of the gloss of the coating film, less change over time, Performance such as easy removal is required.
- tooth coating compositions having quick drying properties so that the coating can be completed in a shorter time, and tooth coating compositions having improved durability of the coated film.
- Patent Document 1 Japanese Patent Application Laid-Open No. 2000-2-1807809
- the invention described in Japanese Patent Application Laid-Open No. 2002-187879 discloses that the use of shellac and mica titanium together enhances the adhesiveness of recerac, and also provides quick drying and long lasting of the applied film. Although it provides an excellent tooth coating composition, it has not been sufficiently satisfactory in hiding power and luster like a natural tooth. In addition, for liquid products with reduced viscosity, The lower jaw had the drawback of being difficult to apply.
- the present invention relates to the use of a combination of shellac and rosin, when applied to teeth (natural teeth, artificial teeth or artificial crowns), has a luster close to that of natural teeth, and the duration of the applied film It is intended to provide a tooth coating composition which has a long hiding power, is excellent in hiding power, and is capable of obtaining a coating having high safety for the human body. Moreover, by properly combining the differences in the properties of the resin between shellac and mouth gin, it is possible to increase the resin concentration without losing quick-drying properties, thereby increasing the strength of the coating and applying it to the teeth. The duration of the coating can be extended.
- This tooth coating composition is composed of a composition containing shellac and rosin as main components, a pigment, a pigment dispersant, a dye, a medicinal component having a cariogenic effect, an antibacterial agent, a thickener, By adding one or more selected from the group consisting of glow reflectors, bleaches and fragrances, cosmetic tooth coating agents, tooth coating agents for preventing tooth decay, adhesives for art materials for teeth, teeth
- An object of the present invention is to provide a tooth coating composition which can be used for various uses such as a paint agent for a tooth.
- the rosin used in the present invention is a solid resin obtained by removing essential oils from the secretion of a plant belonging to the genus Pinus. The rosin is finely crushed and then dissolved in ethanol for use.
- Shellac The content of rosin in the total composition added to the ethanol solution is preferably 1 wt% to 30 wt%. If it is less than 1 wt%, there is not much effect on the strengthening of the coating, and 3 Owt. If it exceeds, it will be difficult to dry, and it will be difficult to use as a tooth coating agent.
- a particularly preferred content of rosin in the entire composition is 5 wt% to 25 wt%. Rosin contains a large amount of abietic acid.
- This abietic acid has an antibacterial activity against Streptococcus myutans, which is the causative bacterium of dental caries. Therefore, the use of rosin is particularly effective in preventing tooth decay without adding the above-mentioned medicinal ingredient having an anti-cariogenic effect.
- the content of shellac is preferably 1 wt% to 30 wt% of the total composition. If the amount of the ceramic is less than 1 wt%, it cannot be put to practical use as a recoating agent having low adhesion to teeth. On the other hand, if the content is more than 3% by weight, it becomes difficult to dry, and cloudiness occurs, resulting in poor aesthetics.
- a particularly preferred content of shellac in the total composition is 5 wt% to 20 wt%.
- the total content of shellac and rosin in the entire composition is preferably from 10 wt% to 31 wt%. If the total content of both is less than 10 wt%, the strength of the coating decreases and the hiding power for hiding the color of the underlying teeth is low, and a beautiful coating cannot be obtained. On the other hand, if the total content of both is more than 31 wt%, the quick-drying property is poor, and the viscosity is too high, making it difficult to apply the coating and unevenness.
- shellac is commercially available in the form of a solution in an ethanol solution.
- rack coat 50 EDS 50% ethanol solution of shellac: Nippon Steel: manufactured by E-Rack Industry Co., Ltd.
- titanium oxide titanium oxide, mica titanium, natural pearl, iron oxide, extender, synthetic pigment, and the like are used.
- the mixing ratio of the pigment is 1 wt% to 2 Owt% It is preferable.
- N-methacrylethyl N, N-dimethylammonium ⁇ a-N-methylcarboxybetaine ⁇ alkyl methacrylate copolymer is used as a pigment dispersant.
- Yukaforma R202 manufactured by Mitsubishi Chemical Corporation, which is commercially available as an ethanol solution containing 3% by weight of the above copolymer, is preferably used.
- the content of the above N-methacrylethyl N, N-dimethylammonium ⁇ -N-methylcarboxybetaine ⁇ alkyl methacrylate copolymer is 1 wt% to 20 wt% in the total composition. Is preferred.
- the dye various dyes recognized as food additives can be used.
- a dye or a synthetic pigment By adding a dye or a synthetic pigment to the tooth coating composition of the present invention, it can be used as a tooth paint for designing various patterns on teeth.
- One or more selected from the group consisting of sodium fluoride, sodium monofluorophosphate, and stannous fluoride can be added as a medicinal ingredient having a pile caries action.
- Antibacterial agents include sodium azulene sulfonate, ⁇ -aminocaproic acid, allantoin, allantoin chlorohydroxyaluminum, allantin dihydroxyaluminum, epidihydrocholesterin, dihydrocholesterol, sodium chloride, glycyrrhizinate, diammonium glycyrrhizinate Disodium glycyrrhizinate, trisodium glycyrrhizinate, dipotassium glycyrrhizinate, monoammonium glycyrrhizinate, j8-glycyrrhetinic acid, isopropylmethylphenol, cetylpyridinium chloride , Decalinium chloride, Benzalkonium chloride, Benzetonium chloride, Alkyldiaminoethylglycine hydrochloride, Chlorhexidine hydrochloride, Triclo
- Plant extracts include fig extract, bean tea extract, oolong tea extract, tea extract, grape seed extract, grape peel extract, blueberry extract, apple extract, eucalyptus extract, roman potato extract, rosemary extract, fennel extract, Examples include myrrh extract, lemon extract, potato extract or sage extract. These extracts have not only an antibacterial effect but also a deodorizing effect.
- Phytoncide is an essential oil extracted from the sap obtained from the leaves and trunks of trees by distillation and other methods. It has an antibacterial effect as well as a deodorant effect.
- Hydroxypropylcellulose can be added as a thickener.
- the viscosity of the tooth composition is increased by adding a viscosity agent. For example, when the tooth composition is applied to the lower jaw teeth, dripping can be prevented and a tooth composition that can be applied neatly can be obtained.
- bleaching agent examples include hydrogen peroxide, calcium peroxide, and urea peroxide.
- Art materials include paper or plastic sheets of various shapes, such as stars, hearts, and diamonds, and fine-grained or crushed stones of beautifully colored stones, or glitter reflectors called lamé. Fine powder or strips can be used. These art materials are designed to apply a tooth coating composition of the present invention to a tooth surface and then apply or scatter these art materials in a semi-dry state to draw a design and enhance the aesthetics of the teeth. Can be used.
- Examples of the luminous reflection material include polyethylene terephthalate / aluminum / epoxy laminate, polyethylene terephthalate / gold laminate, polyethylene terephthalate / polyolefin laminate, polyethylene terephthalate / polymethyl methacrylate laminate, polyethylene / polyethylene terephthalate laminate, Polyethylene-terephthalic acid-bentaerythitol-based polyester laminates and the like can be mentioned.
- These glow reflectors may be added directly to the tooth coating composition of the present invention, or the composition may be adhered to teeth as an adhesive.
- the color tone can be adjusted by adding 1 wt% to 20 wt% of the pigment. In order to cover the dark tooth color, it is desirable to add 5 wt% or more of pigment. By adding a dye, the composition can be used as a paint for tooth art.
- N-methacrylethyl N, N-dimethylammonium as a pigment dispersant
- PAMMA ⁇ - ⁇ -methylcarboxybetaine ⁇ ⁇ ⁇ ⁇ alkyl methacrylate copolymer improved the dispersibility of the pigment, made it less likely to become uneven, and increased the viscosity to make it easier to apply.
- a glossy and translucent tooth coating composition can be provided.
- the discolored tooth pigment is decomposed while applying this composition to the teeth. Can be further whitened.
- the composition can be used as an adhesive for bonding art materials such as seals, crushed stones, and glow reflectors to teeth.
- the present composition has natural tooth luster and its gloss does not change with time, so that the aesthetics of teeth designed for teeth are not impaired.
- Shellac 10 wt% and a combination of rosin with a different blending ratio in the range of 5 wt% to 20 wt%, with the addition of various subcomponents, and lack of either shellac or rosin A comparative test was performed on the comparative example with respect to quick drying, gloss, persistence of the applied film, and easy removal of the used film. [Example 1]
- Rosin 1 5. Owt%, Rack coat 50 EDS (50% ethanol solution of shellac) 20.0 wt% (concentration of shellac alone is 1 Owt%), anhydrous Tanol 36.7wt%, titanium oxide 'Yukaformer ethanol solution (Ducaformer R202 66.7wt%, anhydrous ethanol 23.3wt%) 25.0 wt%, perfume 2.30 wt%, rosemary extract 1. Owt% were mixed well with a stirrer to obtain the desired composition. The ratio of titanium oxide to the total composition was 2.5 wt%.
- Rosin 1 5. Ow t%, rack coat 50 EDS 20. O w t%, absolute ethanol 54.7 w t%, titanium oxide 5.00 wt%, titanium mica 3.0 O w t%, fragrance 2.3 O w t 0 / 0 was thoroughly mixed with a stirrer to obtain a target composition. [Embodiment 3]
- Rosin 1 5. Ow t%, rack coat 50 EDS 20.0 wt%, absolute ethanol 47.7 w t%, titanium oxide 'ethanol solution of Yukaformer 15.0 W t 9 «, fragrance 2.3 O w t% was thoroughly mixed with a stirrer to obtain a target composition. The ratio of titanium oxide to the total composition is 1.5 wt O6.
- Rosin 20 Owt%, Rack coat 50 EDS 20.0 wt%, absolute ethanol 32.7 wt%, titanium oxide Yukaformer ethanol solution 2 5. Owt%, fragrance 2.3 Owt% in a stirrer Mix well and mix the desired composition Obtained. The ratio of titanium oxide to the total composition is 2.5 wt%.
- Rosin 1 5.Ow t%, Rack coat 50 EDS 20.Ow t%, absolute ethanol 49.7 wt Titanium oxide 'Yukaformer ethanol solution 5.00 wt%, Titanium oxide 4.00 wt%, Mica titanium 3. O Owt%, flavor 2.30 wt%, and rosemary extract 1.00 wt% were mixed well with a stirrer to obtain a target composition.
- the ratio of titanium oxide to the total composition is 0.5 wt%.
- Rosin 5.00wt%, rack coat 50 EDS 20. Owt%, absolute ethanol 64.4wt%, titanium oxide 3.80wt%, titanium mica 4.5 Owt%, fragrance 2.3 Owt «1 ⁇ 2 was mixed well with a stirrer to obtain a desired composition.
- Rosin 1 5. Ow t%, rack coat 50 EDS 20. Ow t%, absolute ethanol 39. 75 wt%, titanium oxide 'Yukaformer solution 25.0 w%, red 1.06 1.00% aqueous solution 0.250 wt % In a stirring machine to obtain the target composition.
- the composition to which a pigment is added as in this example can be used as a tooth paint. The ratio of titanium oxide to the total composition was 2.5 wt%.
- Rosin 40.0 wt%, absolute ethanol 47.2 wt%, titanium oxide 2.00 wt%, mica titanium 8.50 wt ° 6, fragrance 2.30 wt% are mixed well with a stirrer to obtain the desired composition. Obtained.
- Rosin 20.0 wt%, absolute ethanol 69.7 wt%, titanium oxide 5.0 wt%. 3.00 wt% of titanium mica and 2.30 wt% of fragrance were mixed well with a stirrer to obtain a target composition.
- Former ethanol solution 25. Owt%, fragrance 2.30 wt% were mixed well with a stirrer to obtain the target composition. .
- the ratio of titanium oxide to the total composition is 2.5 wt%.
- compositions were applied to five subjects only once without overcoating, with the six maxillary anterior teeth remaining exposed, and the time required to dry was measured. With the mouth closed, it was confirmed that the same condition was maintained without peeling even if touched with the tongue, and the measurement was performed five times in 15-second units and the averaged time was given. The results of the five persons were averaged to obtain the drying time.
- Example 5 those with a drying time of more than 180 seconds (Example 5, Comparative Example 1, Comparative Example 5, Comparative Example 6) were omitted because they were not suitable for practical use.
- Each tooth composition was applied, and immediately after application, 2 hours after eating without food (drinks were allowed), and 4 hours later, the teeth were dried and their gloss was observed.
- Table 1 shows the average values.
- Table 2 shows the average values after each hour.
- Table 2 shows the average value of 10 people.
- Example 2 For A2, A3, and A4, a glossy white film was obtained in which the color of the base of the artificial tooth was not visible.
- Example 3 For C 2, C 3, and C 4, a glossy white film was obtained in which the color of the base of the artificial tooth was not visible.
- Example 3 For A2, A3, and A4, a glossy white film was obtained in which the color of the base of the artificial tooth was not visible.
- Example 6 For A2, A3, and A4, a glossy white film was obtained in which the color of the base of the artificial tooth was not visible.
- Comparative Example 2 With respect to A2, A3, and A4, a glossy white film was obtained in which the underlying color of the artificial tooth was not visible.
- Comparative Example 3 For A2, A3, and A4, a glossy white film was obtained in which the underlying color of the artificial tooth was not visible.
- Example 1 For both A2 and A3, a glossy white film was obtained in which the underlying color of the artificial tooth could not be seen.
- A4 had a color similar to that of A2 without the tooth composition, but looked darker than the color of A2 when the tooth composition was coated. For both C 2 and C 3, a glossy white film was obtained in which the underlying color of the artificial tooth could not be seen.
- C4 had a color close to C2 when the tooth composition was not applied, but appeared blackish than the color of C2 when the tooth composition was applied.
- Example 4 For both A2 and A3, a glossy white film was obtained in which the color of the base of the artificial tooth could not be seen.
- A4 had a color close to A2 when the tooth composition was not applied, but it was darker than A2 when the tooth composition was applied.
- C4 had a color close to C2 when the tooth composition was not applied, but appeared blackish than the color of C2 when the tooth composition was applied.
- A4 had a color close to A2 when the tooth composition was not applied, but it was darker than A2 when the tooth composition was applied.
- Example 6 (Sec) Immediately 2 hours later Time later Time later Example 1 60 3.0 2.6 1.4 Example 2 45 3.0 2.6 1.4 Example 3 30 2.6 1.2 0.6 Example 4 60 3.0 2.6 1.2 Example 5 180 Example 6 45 1.6 0.8 0.4 Example 7 30 1.2 1.0 0.4 Example 8 45 1.2 1.0 0.4 Comparative Example 1 255 Comparative Example 2 150 2.4 1.8 0.8 Comparative Example 3 150 3.0 0.8 0 Comparative Example 4 20 1.2 0.8 0 Comparative Example 5 210 Comparative Example 6 180
- the tooth coating composition of the present invention may be used in addition to cosmetic or health tooth coating agents, paints for drawing designs on teeth for artistic purposes, paper or plastic seals, and beautiful colors. It can also be used as an adhesive to adhere crushed stone, powdered or flake-shaped glow reflectors to teeth for art purposes
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020067003239A KR101103138B1 (ko) | 2003-08-27 | 2004-08-26 | 치아 도포용 조성물 |
AU2004268452A AU2004268452B2 (en) | 2003-08-27 | 2004-08-26 | Tooth Coating Composition |
CA2534063A CA2534063C (en) | 2003-08-27 | 2004-08-26 | Aesthetic tooth coating composition comprising shellac and rosin |
US10/556,914 US20070041913A1 (en) | 2003-08-27 | 2004-08-26 | Tooth coating composition |
JP2005513530A JP4527666B2 (ja) | 2003-08-27 | 2004-08-26 | 歯牙塗布用組成物 |
EP04772654A EP1666019A4 (en) | 2003-08-27 | 2004-08-26 | COMPOSITION APPLYING TO TEETH |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003302282 | 2003-08-27 | ||
JP2003-302282 | 2003-08-27 |
Publications (1)
Publication Number | Publication Date |
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WO2005020937A1 true WO2005020937A1 (ja) | 2005-03-10 |
Family
ID=34269172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/JP2004/012698 WO2005020937A1 (ja) | 2003-08-27 | 2004-08-26 | 歯牙塗布用組成物 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20070041913A1 (ja) |
EP (1) | EP1666019A4 (ja) |
JP (1) | JP4527666B2 (ja) |
KR (1) | KR101103138B1 (ja) |
CN (1) | CN1842314A (ja) |
AU (1) | AU2004268452B2 (ja) |
CA (1) | CA2534063C (ja) |
WO (1) | WO2005020937A1 (ja) |
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JP2008174542A (ja) * | 2006-12-18 | 2008-07-31 | Lion Corp | 口腔用組成物 |
JP2009221167A (ja) * | 2008-03-18 | 2009-10-01 | Mandom Corp | 抗菌剤組成物及び防臭剤用組成物 |
JP2011516500A (ja) * | 2008-04-04 | 2011-05-26 | コルゲート・パーモリブ・カンパニー | 口腔病学およびデンタルケアに使用するためのセラックロウおよび漂白セラックを含む口腔用組成物 |
JP2013507347A (ja) * | 2009-10-08 | 2013-03-04 | タイガ ポリマーズ オーワイ | 抗微生物組成物 |
JP2015164467A (ja) * | 2014-02-28 | 2015-09-17 | クラシエフーズ株式会社 | 歯面染色塗布液及びそれを用いた歯面汚れ除去評価方法 |
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2004
- 2004-08-26 WO PCT/JP2004/012698 patent/WO2005020937A1/ja active Application Filing
- 2004-08-26 CN CNA2004800243012A patent/CN1842314A/zh active Pending
- 2004-08-26 US US10/556,914 patent/US20070041913A1/en not_active Abandoned
- 2004-08-26 JP JP2005513530A patent/JP4527666B2/ja active Active
- 2004-08-26 AU AU2004268452A patent/AU2004268452B2/en active Active
- 2004-08-26 CA CA2534063A patent/CA2534063C/en active Active
- 2004-08-26 KR KR1020067003239A patent/KR101103138B1/ko active IP Right Grant
- 2004-08-26 EP EP04772654A patent/EP1666019A4/en not_active Withdrawn
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JPS62277953A (ja) * | 1986-05-26 | 1987-12-02 | 株式会社ジーシー | 歯面保護用塗布材 |
JPH02144069A (ja) * | 1988-11-28 | 1990-06-01 | Showa Yakuhin Kako Kk | 歯科用仮封材組成物 |
JPH07179842A (ja) * | 1993-12-24 | 1995-07-18 | Tdk Corp | 接着剤、その製造法、及びそれを用いた電子部品の製造法 |
JPH1171219A (ja) * | 1997-08-28 | 1999-03-16 | Mitsubishi Pencil Co Ltd | 歯の塗布液 |
JPH11155882A (ja) * | 1997-11-28 | 1999-06-15 | Kanebo Ltd | 歯科用艶出し材 |
JP2001213732A (ja) * | 2000-01-31 | 2001-08-07 | Hanix:Kk | 歯牙用コーティング剤 |
Non-Patent Citations (1)
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See also references of EP1666019A4 * |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008174542A (ja) * | 2006-12-18 | 2008-07-31 | Lion Corp | 口腔用組成物 |
JP2009221167A (ja) * | 2008-03-18 | 2009-10-01 | Mandom Corp | 抗菌剤組成物及び防臭剤用組成物 |
JP2011516500A (ja) * | 2008-04-04 | 2011-05-26 | コルゲート・パーモリブ・カンパニー | 口腔病学およびデンタルケアに使用するためのセラックロウおよび漂白セラックを含む口腔用組成物 |
JP2013507347A (ja) * | 2009-10-08 | 2013-03-04 | タイガ ポリマーズ オーワイ | 抗微生物組成物 |
JP2015164467A (ja) * | 2014-02-28 | 2015-09-17 | クラシエフーズ株式会社 | 歯面染色塗布液及びそれを用いた歯面汚れ除去評価方法 |
JP2020002071A (ja) * | 2018-06-28 | 2020-01-09 | 株式会社バイオデザイン | 覆髄剤 |
JP7101365B2 (ja) | 2018-06-28 | 2022-07-15 | 株式会社バイオデザイン | 覆髄剤 |
WO2021125315A1 (ja) * | 2019-12-19 | 2021-06-24 | 株式会社ハニック・ホワイトラボ | 口腔内粘膜被覆用抗炎症性液状組成物、およびこれを用いた口内炎の予防および/または治療用医薬組成物 |
Also Published As
Publication number | Publication date |
---|---|
JPWO2005020937A1 (ja) | 2006-10-26 |
EP1666019A4 (en) | 2010-05-26 |
CA2534063C (en) | 2012-03-06 |
AU2004268452A1 (en) | 2005-03-10 |
AU2004268452B2 (en) | 2011-02-03 |
CA2534063A1 (en) | 2005-03-10 |
US20070041913A1 (en) | 2007-02-22 |
KR101103138B1 (ko) | 2012-01-04 |
CN1842314A (zh) | 2006-10-04 |
JP4527666B2 (ja) | 2010-08-18 |
EP1666019A1 (en) | 2006-06-07 |
KR20060064641A (ko) | 2006-06-13 |
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