WO2004105590A1 - カプセル型医療装置 - Google Patents
カプセル型医療装置 Download PDFInfo
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- WO2004105590A1 WO2004105590A1 PCT/JP2003/016692 JP0316692W WO2004105590A1 WO 2004105590 A1 WO2004105590 A1 WO 2004105590A1 JP 0316692 W JP0316692 W JP 0316692W WO 2004105590 A1 WO2004105590 A1 WO 2004105590A1
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- Prior art keywords
- capsule
- data
- capsule medical
- medical device
- image
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00011—Operational features of endoscopes characterised by signal transmission
- A61B1/00016—Operational features of endoscopes characterised by signal transmission using wireless means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/0002—Operational features of endoscopes provided with data storages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/041—Capsule endoscopes for imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
- A61B5/0031—Implanted circuitry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7232—Signal processing specially adapted for physiological signals or for diagnostic purposes involving compression of the physiological signal, e.g. to extend the signal recording period
Definitions
- the present invention relates to a force-pussel-type medical device that performs a medical treatment by using a force-pussel-type medical device inserted into a body.
- Japanese Patent Application Laid-Open No. 2000-3404-2522 there is Japanese Patent Application Laid-Open No. 2000-3404-2522.
- This prior example is an in-dwelling type endoscope apparatus in which a swallowable endoscope and an extracorporeal device are wirelessly connected, and discloses that the extracorporeal device performs a bending operation.
- U.S. Patent No. 6,402,686 and U.S. Patent No. 6,402,887 also have a swallowable endoscope and an external device that are wirelessly connected to a self-contained endoscope. Is disclosed.
- Japanese Patent No. 32794909 discloses a medical capsule for treatment, which is disclosed in Japanese Patent Application Laid-Open No. 2000-33424, U.S. Patent 64042. No. 686 and U.S. Patent No. 6,402,687 disclose that the extracorporeal device performs the bending operation or the like wirelessly as described above, but the operation state is maintained or changed. If it is necessary to do so, the user needs to send a signal from the external device, which is inconvenient.
- Patent No. 3,279,409 does not describe optimizing the release amount of a chemical solution or the like.
- the output of the detection means such as the image sensor and the sensation sensor, the operation of the means for releasing the medicine, and the operation of the means for collecting the tissue and the body fluid are easily affected by the assembled state.
- an appropriate image cannot be obtained in a small intestine or a narrow region of a lumen such as an esophagus unless an exposure amount is kept low.
- an appropriate image can be obtained unless the exposure is increased and taken. And it becomes difficult.
- An object of the present invention is to provide a portable medical device.
- Another object of the present invention is to provide a force-pull medical device capable of improving the state of the capsule medical device at the time of shipment or adjustment by changing the setting.
- An object of the present invention is to provide a force-pussel-type medical device capable of controlling a force-pusel-type medical device by a control signal from the outside of the body and operating under more suitable conditions. Disclosure of the invention
- a receiving device that receives data from outside the force-pussel-type medical device
- a storage device that enables the stored data to be rewritten based on the data received by the receiving device
- the setting state is set to an appropriate state or the operation state is changed to a more appropriate operation state by changing the storage data stored in the storage unit. Things can be done easily.
- FIGS. 1 to 12B relate to a first embodiment of the present invention
- FIG. 1 is a block diagram showing the overall configuration of a force-pusel-type medical device according to the first embodiment of the present invention.
- FIG. 2 is a cross-sectional view showing a schematic structure of a force-pressed medical device
- FIG. 3 shows typical data contents stored in a memory or a non-volatile memory
- FIG. 4 shows a format when information is wirelessly transmitted.
- FIG. 5 shows a typical command
- 6A and 6B show explanatory views of how the imaging range of the image sensor is determined
- Fig. 8 shows how the color balance (the luminance distribution position of each color) is set to an appropriate position.
- Fig. 9A shows the configuration of a lighting circuit using light-emitting elements.
- FIG. 9B shows an explanatory diagram of the operation of the lighting circuit
- FIG. 10 shows a circuit diagram of the configuration of the force sensor
- Figure 11 shows the shooting mode command code for shooting.
- FIG. 12A shows a flowchart of the processing content in the single image shooting mode
- FIG. 12B shows a flowchart of the processing contents in the continuous shooting mode.
- FIG. 13 is a block diagram showing the overall configuration of a force-pressed medical device according to the second embodiment of the present invention.
- FIG. 14 is a block diagram showing the overall configuration of a force-pressed medical device according to the third embodiment of the present invention.
- FIG. 15 shows a block diagram of the overall configuration of the capsule medical device according to the fourth embodiment of the present invention.
- FIGS. 1 to 12B A first embodiment of the present invention will be described with reference to FIGS. 1 to 12B.
- a capsule medical device 1 is a capsule having a built-in image sensor that is inserted into a body cavity of a patient (not shown) by swallowing and performs imaging.
- an extracorporeal device 4 disposed outside the body for storing information obtained by the capsule 3 or for storing information obtained by the capsule 3.
- the capsule-shaped capsule 3 is drunk together with water and the like in the same manner as the drug, and a screening examination of the esophagus, duodenum, small intestine, and colon is performed. It can be carried out.
- the extracorporeal device 4 receives the image data transmitted wirelessly by the capsule 3, detects the operation state of the force capsule 3 such as the imaging state of the capsule 3, and adjusts the operation state of the capsule 3 requiring adjustment after assembly.
- the operation of the capsule 3 is set to an appropriate operation state by sending correction data for setting the operation state to an appropriate state and storing it in the storage means (nonvolatile memory or memory) of the capsule 3 I can do it.
- this force capsule 3 has a hemispherical transparent member 5a formed at one end (referred to as a front end) of a cylindrical or force vessel-shaped closed storage container 5, and is formed near the center thereof.
- the objective optical system 6 is attached to the lens frame so as to face the transparent member 5a, and the light-emitting elements constituting the illumination circuit 7 (see FIG. A plurality of white LEDs 7a and 7b are arranged.
- An image sensor 8 such as a CMOS sensor is disposed at the image forming position of the objective optical system 6, and on the back side of the image sensor 8, signal processing for the image sensor 8 and the like and signal processing for performing overall control are performed.
- a control circuit 9, a wireless circuit 10 for performing wireless communication, and a plurality of button-type batteries 11 for supplying operating power to the image sensor 8, the signal processing & control circuit 9, and the like are arranged.
- an antenna 12 for radio wave transmission and reception that is connected to the radio circuit 10 and wirelessly communicates with the extracorporeal device 4 is arranged on the side adjacent to the image sensor 8, an antenna 12 for radio wave transmission and reception that is connected to the radio circuit 10 and wirelessly communicates with the extracorporeal device 4 is arranged.
- a switch 13 for ONZOFF of the supply of power is arranged.
- the image sensor 8, the signal processing circuit 9, and the wireless circuit 10 are electrically connected through a flexible board 14, and the flexible board 14 is further connected to a battery 11 through a switch 13. I have.
- a force sensor 15 is attached so that the sensor part is exposed to the outside from the storage container 5, and a signal detected by the force sensor 15 is input to a signal processing & control circuit 9, and the capsule 3 Movement can be detected.
- FIG. 1 shows a more detailed internal configuration of the electric system of the capsule 3 and the extracorporeal device 4.
- the illumination circuit 7 includes white LEDs 7a and 7b as light emitting elements in FIG. 2 and a light emission drive circuit thereof.
- the inner wall and the like in the body cavity illuminated by the white LEDs 7a and 7b are connected to the objective optical system 6
- the image is formed by An image pickup surface of an image sensor 8 as an image pickup means is arranged at the image forming position, and an image is picked up by the image sensor 8.
- the illumination circuit 7 is controlled by an imaging drive control circuit 21 constituting a signal processing & control circuit 9, and the image sensor 8 is driven via an analog processing unit 22, and the captured image signal is After being processed by the analog processing section 22, it is converted into a digital signal (image data) by the imaging drive control circuit 21, and then input to the compression processing circuit 23, where it is subjected to compression processing.
- T / JP2003 / 016692 The fog sensor 15 is also connected to the imaging drive control circuit 21 and controlled by the imaging drive control circuit 21 composed of a CPU and the like, and detected by the fog sensor 15. The movement of capsule 3 is detected from the received signal.
- the imaging drive / control circuit 21 is constituted by an electrically rewritable EEPROM or the like as data storage means (which retains data even after power is turned off), and is electrically rewritable. It is connected to a volatile memory (which may be a register) that is composed of a high-speed static RAM (data disappears after power off). Then, the CPU of the imaging drive Z control circuit 21 performs operations such as imaging with reference to information (data) stored in the nonvolatile memory 24 and the memory 25.
- the nonvolatile memory 24 mainly stores data for determining (specifying) the operation of the capsule 3 in the initial state. Further, the memory 25 which is volatile and can be rewritten at high speed, etc., stores data which determines an operation different from the initial state after the initial state.
- FIG. 3 shows the contents of data stored in the memory 25, in which parameters, control information and the like for determining the function and operation of the capsule 3 are stored for each predetermined address. Then, a command can be sent from the extracorporeal device 4 to the imaging drive / control circuit 21 of the capsule 3, and the operation of the capsule 3 can be controlled by the command, and the parameter data in the memory 25 can be rewritten.
- the setting for changing the operation parameters of the capsule 3 can also be made by the instruction of, as shown in FIG.
- FIG. 4 shows a format for transmitting a command or data from the external device 4 to the force cell 3.
- the format is command (01) or data (02), followed by code and parameter items.
- the command is as shown in Fig. 5, after the code (command code), the parameters required for that command are set. Is done.
- capsule ID + data follows the data type.
- the parameters are capsule ID + address + data as parameters.
- FIG. 4 shows one specific example.
- the instruction content "OB” of the command is a nonvolatile memory rewrite instruction
- the rewrite content address "0000” is a gain setting instruction
- “80” sets (rewrites) the gain value to 80H.
- Imaging drive / control circuit 2 1 capsule 3 (CPU) of the format of FIG. 4, performs an operation corresponding to the command or the like sent from the body outside of the apparatus 4.
- FIG. 5 shows a specific example of correspondence information of a code command (instruction) stored in a ROM or the like in the imaging drive Z control circuit 21 of the capsule 3.
- the external device 4 described later also stores correspondence information substantially similar to that shown in FIG. 5, reads information of a command corresponding to the information of the code transmitted from the capsule 3, and performs a corresponding operation.
- the capsule 3 mainly transmits the captured image data to the extracorporeal device 4, the capsule 3 transmits the image data in the format shown in FIG.
- the image data compressed by the compression processing circuit 23 is stored in the memory 26, read out from the memory 26, sent to the radio circuit 10, modulated at a high frequency, and radiated by radio waves from the antenna 11 Is done.
- the DC power from the battery 11 is supplied to a power supply circuit 27 via a switch 13, and is converted into a voltage for appropriately operating each module (circuit) by the power supply circuit 27. Supplied to Vcc.
- the power supply circuit 27 is also controlled by the imaging drive control circuit 21.
- the power supplied to some circuits in the capsule 3 is cut off, and the operation of the cut off circuit is set to a dormant state. It can also be set to prevent wasted power consumption by that circuit.
- the extracorporeal device 4 receives the radio wave transmitted from the capsule 3 side by the antenna 31, further demodulates it by the radio circuit 32, and stores it in the memory 33.
- the image data stored in the memory 33 is read out by the control circuit 34 and sent to the signal processing circuit 35.
- the signal processing circuit 35 expands the image data. Is generated.
- This image data is sent to an image position detection circuit 36 and a color balance brightness detection circuit 37, and the image position and the force balancer brightness are detected, respectively.
- Each detection signal is sent to a correction amount calculation circuit 38 and 39, respectively, to calculate a correction amount to be corrected.
- the correction amounts calculated by the correction amount calculation circuits 38 and 39 are sent to the control circuit 34, and the control circuit 34 stores the data of the correction amounts in the memory 33.
- the data stored in the memory 33 is modulated at a high frequency by the radio circuit 32 and can be transmitted from the antenna 31 to the capsule 3 by radio waves.
- the control circuit 34 is also constituted by a CPU or the like.
- the instruction code of FIG. 5 is stored in a ROM or the like inside the control circuit 34, and when the data of the correction amount is transmitted, the memory 25 Is transmitted in a format to which a rewrite instruction or the like is added.
- the signal processing circuit 35 or the control circuit 34 is connected to the display device 40, and displays the decompressed image, the capsule ID transmitted from the capsule 3, and the like, so that the user can confirm or monitor. I can do it.
- the control circuit 34 is connected to an input circuit 41 composed of a keyboard or the like. When the operation of the capsule 3 is controlled from the external device 4, the control circuit 34 can perform command input from the input circuit 41. it can.
- the command data and the like input from the input circuit 41 are also stored in the memory 33 from the control circuit 34 and can be transmitted by radio waves in the same manner as the correction amount data. Also, a battery 42, a switch 43, and a power supply circuit 44 are provided in the extracorporeal device 4, and the DC voltage generated by the power supply circuit 44 is supplied to the power supply terminal V cc of each module (circuit). Supplied to
- Radio waves radiated from the antenna 31 of the extracorporeal device 4 are received by the antenna 11 of the capsule 3, demodulated by the radio circuit 10, and then sent to the imaging drive control circuit 21.
- This imaging drive The CPU constituting the control circuit 21 stores the demodulated data in the memory 25 or the like, and the capsule 3 operates based on the stored data.
- the capsule 3 has a non-volatile memory 24 for storing information on the initial setting operation, and the operating state of the capsule 3 can be controlled by writing information in a volatile manner.
- the user such as a medical staff, can adjust and set the appropriate operation state by changing the information to be written in the memory 25, etc.
- the CPU of the control circuit 34 of the body exterior device 4 transmits an inquiry command of code 01 in FIG. 5 as to whether or not the capsule 3 exists in the vicinity.
- the capsule 3 determines the command, adds a capsule ID as a unique number written in the capsule 3 at the time of manufacturing or the like to the unique number notification command, and transmits the command to the external device 4. .
- the extracorporeal device 4 extracts (acquires) the capsule ID, stores it in a register or the like inside the control circuit 34, and displays the capsule ID on the display device 40.
- a user such as a medical staff sends a connection request command to the capsule 3 having the obtained capsule ID from the input circuit 41 of the extracorporeal device 4 and receives the command.
- the capsule 3 and the extracorporeal device 4 are set to a state in which bidirectional wireless communication is performed.
- the capsule 3 can be set to the operating state.
- a subject serving as a white reference such as a white sheet is arranged in front of the transparent member 5a of the capsule 3, and a command to start imaging is transmitted.
- the capsule 3 receives this command, and by judging the command, starts illumination by the illumination circuit 7 and photography (imaging) by the image sensor 8.
- the non-volatile memory 24 stores, for example, the control contents of a single-shot mode, which will be described later, as a default shooting mode.
- the CPU of the shooting drive control circuit 21 of the capsule 3 stores the nonvolatile memory 2
- the photographing operation and the like are performed in accordance with the control contents written in 4 (in the initial state, the contents of the memory area of the memory 25 are cleared).
- the captured image data is compressed and transmitted to the extracorporeal device 4.
- the extracorporeal device 4 decompresses the transmitted image data by the signal processing circuit 35, and performs the image position detection circuit 36 and the color correction. Output to the brightness detection circuit 37.
- the image position detection circuit 36 calculates the luminance distribution of the captured image, and outputs it to the correction amount calculation circuit 38.
- the correction amount calculating circuit 38 calculates an image circle Ri which is a substantial imaging range by the objective optical system 6 depending on whether or not a predetermined threshold value is exceeded, as shown in FIG. For example, the horizontal start position, the horizontal end position, the vertical start position, and the vertical end position on the imaging surface 8a of the image sensor 8, which are preset as defined by the vertical line and the horizontal line circumscribing the image circle Ri, Each is calculated and sent to the control circuit 34.
- the control circuit 34 adds the data at these positions to the capsule 3 as correction amount data and transmits it to the memory rewrite instruction command in FIG.
- the capsule 3 stores the received position data in the memory area at addresses 30, 40, 50, 60 shown in FIG.
- the capsule 3 transmits only the image data in the square imaging area determined by the position data to the extracorporeal device 4.
- the imaging region after assembling the capsule 3 in this manner, it is possible to appropriately adjust so that data obtained in a pixel portion where imaging is not actually performed is not transmitted to the extracorporeal device 4 side. Further, by performing such adjustment, the adjustment at the time of assembling the objective optical system 6 of the capsule 3 and the image sensor 8 can be simplified.
- the color Parasno brightness detection circuit 37 detects (calculates) a histogram of brightness (brightness) in the captured image, for example, as indicated by a dashed line in FIG. Then, the color balance brightness detection circuit 37 sends the detected histogram to the correction amount calculation circuit 39.
- the reference data of the histogram of the standard luminance distribution position is stored in the correction amount calculating circuit 39 in advance, and the correction amount for obtaining the luminance distribution indicated by the solid line is calculated based on the reference data.
- the correction amount is transmitted from the control circuit 34 to the capsule 3 side, and the adjustment of the light emission amount and the like by the illumination circuit 7 of the capsule 3 will be described later with reference to FIGS. 9A and 9B. It is adjusted so that
- the color balance brightness detection circuit 37 calculates the luminance distribution of the G, B, and R components in the captured image.
- the luminance distribution of G is substantially set to an appropriate state by adjusting the luminance distribution of luminance in FIG.
- the R and B components generally deviate from the proper state shown by the solid line so that a color balance is required.
- the correction amount is calculated by the correction amount calculation circuit 39 and sent to the control circuit 34.
- the control circuit 34 transmits from the control circuit 34 to the capsule 3 side, and the data of the R gain setting and the G gain setting of the memory 25 of the capsule 3 are changed and set so as to be in an appropriate state (from 0 in the initial state).
- the histogram is adjusted so as to form a histogram as shown by the solid line.
- the image is set to a color-balanced (white balance) imaging state that generates a color image signal that appears white.
- the lighting circuit 7 includes two white LEDs 7a connected in series between the emitter of the switching transistor Q1 and the ground, and the switching transistor Q1 applied to its base to emit light.
- the element instruction signal is turned ON, light emission is driven by current flowing from the collector side.
- the two white LEDs 7b are driven by the switching transistor Q2.
- Power for light emission is supplied to the collectors of both transistors Q 1 and Q 2 via a counter 51, a comparison circuit 52, a dryno 53 and an electronic trimmer resistor 54.
- the clock CLK as shown in FIG. 9B is input to the counter 51, and the output counted by the counter 51 is input to the comparison circuit 52, which outputs the reference light emission time. Compare with the signal value of the interval instruction.
- a signal of “H” is output to the driver 53 during the time of the reference light emission time instruction, and the signal of the light emission current instruction is applied to the electron trimmer resistor 54.
- bird The resistance value of the resistor 54 can be set variably.
- the initial setting state before adjustment specifically, the value of the emission time instruction when the luminance distribution is as shown by the dashed line in FIG. 7 is as shown by the dashed line in FIG. 9B.
- the emission time after the re-adjustment by the correction instruction by the correction amount calculation circuit 39 is set to the emission time instruction as shown by the solid line in FIG. 9B.
- the signal value of the light emission time instruction is sent to the comparison circuit 52, and the increased value is set.
- the light emission amount is increased, so that the luminance histogram in the image obtained by imaging is set (adjusted) as shown by the solid line in FIG. You.
- the light emission current instruction is set to the value indicated by the one-dot chain line in FIG. 9B in the case of the initial setting, it is increased as shown by the solid line after the adjustment.
- the amount of light emission can be increased by changing the number of light emitting element instruction signals from one to two.
- FIG. 9A also shows, for reference, an address corresponding to the data content of the memory 25 in FIG.
- the gain and the like of the adjustment circuit can be adjusted so that the force sensor 15 is brought into a stable operation state.
- FIG. 10 shows an adjustment circuit 81 of the force sensor 15, and the adjustment circuit 81 except the force sensor 15 is constituted by, for example, a part of an imaging drive control circuit 21.
- Fact sensor 15 (the equivalent resistance is indicated by R), three resistors R 1, R 2, R 3, and an electronic trimmer resistor 8 2 a, 8 connected in series to resistors R 1 and R 3, respectively
- a bridge circuit is formed by 2b and a constant voltage is supplied from the constant voltage source 83.
- the resistance of the electronic trimmers 8 2 a and 8 2 b is variably set according to the sensor adjustment instruction signal, and the bridge circuit is adjusted to a balanced state when no force is applied to the force sensor 15. Have to be able to.
- the force applied to the capsule 3 by the camera sensor 15 can be detected stably.
- the color imaging function using the capsule 3 after assembly and the illumination function for imaging are set to an appropriate state, and the sensor state of the camera sensor 15 is set to an appropriate operation. Or set to a state.
- the operation state of the capsule 3 may be changed from the external device 4.
- the input circuit 41 of the extracorporeal device 4 may be operated to send the mode switching instruction command shown in FIG. 3 to change the single-shot mode shown in FIG. 11 to the continuous shooting mode. .
- the shooting process shown in Fig. 12A is performed, and in the continuous shooting mode, the shooting process shown in Fig. 12B is performed.
- step S1 when the image is captured by the image sensor 8 of the capsule 3, the captured image is sent to the analog processing unit 22. After analog processing, the signal is converted into a digital signal, and compressed (in the compression processing circuit 23) as shown in step S2.
- step S3 the image data compressed as shown in step S3 is stored in the memory 26.
- the compressed image data stored in the memory 26 is transmitted by radio waves via the wireless circuit 10 and the antenna 11 as shown in step S4.
- step S5 data transmission is performed until the transmission of one image data is completed, and when the transmission of one image data is completed, the process proceeds to step S6, and the memory 26 is cleared.
- step S6 the memory 26 is cleared.
- step S6 the memory 26 is cleared.
- the operation of the single shooting is ended.
- 3 016692 In this mode, a single image is captured. After the capsule 3 is assembled, its operation is confirmed. It is suitable for obtaining necessary image information and the like without repetitive photographing and other unnecessary power consumption.
- step S4 a process of determining whether the remaining amount of the memory 26 is 0 is performed between steps S3 and S4 in FIG. If the remaining amount does not become 0, the process returns to step S1, and the processing from step S1 to step S4 is repeated. That is, shooting is repeated until the remaining amount of the memory 26 becomes zero. Then, after repeating the shooting until the remaining amount of the re-memory 26 becomes 0 in step S7, the data transmission in step S4 is performed, and until the transmission is completed in step S5 (that is, the memory 26 (Until the transmission of the image data of the number of shots is completed) until the remaining capacity of the memory becomes 0), and then the memory 26 is cleared.
- the single-shot shooting mode and the continuous shooting mode are prepared, and shooting can be performed in a mode suitable for the use state.
- a desired time interval is selected from timers 1 to 3 that can be set to three time intervals.
- the user-friendliness can be selected according to the inspection target, etc., improving usability.
- other functions include a code for transmitting, a code for notifying that reception is enabled, a code for clearing memory 26, etc., a code for checking memory 26, etc., and a memory.
- Codes for setting addresses in 25, 26, etc., codes for resetting, etc. are also provided, and it has a wealth of functions that allow more detailed control of the operation of forceps 3 and the like.
- brightness control such as the amount of illumination light may be performed at an appropriate time interval (for example, about several times the imaging interval).
- the average brightness of a plurality of images taken at the above time intervals is detected by the extracorporeal device 4, and the appropriate amount of illumination light in that state is calculated from the extracorporeal device 4 by comparison with a reference value.
- the capsule 3 sends the data of the correction amount to be corrected to the reference value to the capsule 3, and adjusts the light emission amount of the white LEDs 7a and 7b to an appropriate value by the capsule 3 during the shooting operation by the capsule 3. It can be performed all the time.
- the amount of electric energy used by the battery 11 used for lighting can be appropriately adjusted, and wasteful consumption of electric energy can be effectively prevented.
- the time interval between imaging is shortened near a certain part and the time interval between imaging is increased for a part far from the part to be inspected. It can be used flexibly for a wide range of applications.
- the external device 4 monitors the movement of the capsule 3 using the visual sensor 15. It is also possible to easily detect a state in which the capsule 3 has been stopped by the signal from the sensation sensor 15 and quick response is also possible.
- the color imaging function using the capsule 3 after assembly and the illumination function for imaging are set to an appropriate state, and the sensor state of the camera sensor 15 is set to an appropriate operation. Or set to a state.
- the operating state of the capsule 3 is appropriately changed according to the part to be inspected by changing the parameters of the memory 25 of the capsule 3 or instructing the switching. You can also. For this reason, the usability is greatly improved compared to the previous example.
- image information and the like for the inspection target can be obtained with appropriate settings and operating states according to the inspection target. More specifically, depending on the inspection target, it is possible to prevent the lighting and photographing of the battery 11 from being performed excessively at a time interval that is too short, thereby preventing the electric energy of the battery 11 from being consumed halfway. At the same time, it is possible to obtain appropriately photographed image information with a balance of power at appropriate time intervals, and to obtain an image that is easy to diagnose based on an illumination state of appropriate brightness.
- the initial state Changes can be made after assembly.
- the setting state and the like can be set to an appropriate state by changing the information stored in the storage means, and a more appropriate operation can be performed. It can be easily changed to a state. 2003/016692
- FIG. 13 shows a capsule medical device 1B according to a second embodiment of the present invention.
- the capsule medical device 1 B shown in FIG. 13 is composed of a capsule 3, a display control device 61 having a display function separately from the extracorporeal device 4 B and the body exterior device 4 B, and a display control device 61. It comprises a display device 40 and an input circuit 41 to be connected.
- Capsule 3B in FIG. 13 differs from capsule 3 in FIG. 1 in that non-volatile memory 24 is not provided and only rewritable and volatile memory 25 is used to store information necessary for the operation of capsule 3B. Memory 25, one place to save.
- the memory 25 may have the function of the memory 26 so that the memory 26 is omitted.
- the extracorporeal device 4B has a configuration in which the functions of the image position detection circuit 36 and the power balance brightness detection circuit 37 in the extracorporeal device 4 in FIG. 1 are shifted to the external display control circuit 61. ing.
- the display control circuit 61 has a built-in control circuit 62 for controlling display, and performs transmission and reception of data with the control circuit 34 of the extracorporeal device 4B.
- the control circuit 62 is an image position correction amount calculating circuit that integrates the image position detecting circuit 36, the color balance brightness detecting circuit 37 and the correction amount calculating circuits 38 and 39 in FIG. 1, respectively. 36 B and a color balancer brightness correction amount calculation circuit 37 B are connected.
- the display control circuit 61 has a built-in battery or a power supply circuit for generating a DC power supply from AC power from a commercial power supply.
- the cost of capsule 3B can be further reduced.
- the other effects are almost the same as those of the first embodiment.
- FIG. 14 shows a capsule medical device 1C according to the third embodiment of the present invention.
- the capsule medical device 1 G includes a capsule 3 C and an extracorporeal device 4 C.
- the capsule medical device 1 C is the capsule medical device 1 shown in FIG. 1, and the capsule 3 C is an extracorporeal device 4 C.
- the external device 4 is configured to perform transmission only by radio waves, while the external device 4 transmits by infrared rays when transmitting to the capsule 3C.
- the extracorporeal device 4C is provided with an infrared transmitter 71 connected to the control circuit 34.
- the infrared transmitter 71 modulates data transmitted from the control circuit 34 with infrared rays. And send.
- the capsule 3C has an infrared receiver 72 connected to the imaging drive control circuit 21.
- the infrared receiver 72 receives infrared light transmitted from the infrared transmitter 71.
- the signal is demodulated and sent to the imaging drive / control circuit 21.
- the radio circuit 10 ′ of the capsule 3 C has a function of modulating data from the memory 26 and emitting the radio wave from the antenna 11, and does not have a function of demodulation.
- the radio circuit 32 ′ of the extracorporeal device 4C does not have a function of demodulating radio waves received by the antenna 31 and outputting the demodulated radio waves to the memory 33 side for modulation.
- the present embodiment after assembling the capsule 3C and before the patient swallows the capsule 3C, it is possible to perform almost the same function (operation) as in the first embodiment.
- the extracorporeal device 4C when a patient swallows, what kind of examination is usually performed is determined. Therefore, necessary information is transmitted from the extracorporeal device 4C to the capsule 3C by infrared rays according to the examination, and the memory 25 May be stored in advance.
- FIG. 15 shows a capsule medical device 1D according to a fourth embodiment of the present invention.
- This capsule medical device 1D is provided with a lighting device for imaging and a lighting device as in the first embodiment.
- the medicine can be administered in a state where the image can be confirmed by the imaging.
- the capsule 3D determines the operation of the capsule 3D, the illumination circuit 7 and the image sensor 8, the imaging drive control circuit 21 ′ for controlling them, the radio circuit 10 and the antenna 11 Memory (register) 25 for storing parameters to be executed.
- the imaging drive control circuit 21 ′ has a configuration that also has the function of the analog processing section 22 in FIG. Is shown.
- the capsule 3D further includes a drug release valve 91 that is opened on the outer surface of the storage container of the capsule 3D to release a drug, and a drug release valve 91 and a pipe line.
- a drug release valve 91 that is opened on the outer surface of the storage container of the capsule 3D to release a drug
- a drug release valve 91 and a pipe line are connected to each other, a cylindrical medicine storage section 92 for storing a medicine, a cylinder feeding apparatus 94 for feeding a slidable cylinder 93 to the medicine storage section 92, and a cylinder feeding apparatus 94.
- a dosing control unit 95 for controlling the drive of the drug and controlling the opening and closing of the drug release valve 91.
- administration control unit 95 by transmitting a command from the extracorporeal device 4 or the like, administration of a drug or the like can be performed via the administration control unit 95.
- the extracorporeal device 4D includes an antenna 31 for transmitting and receiving radio waves to and from the antenna 11 of the capsule 3D, a radio circuit 32 for performing modulation and demodulation, A control circuit 3 4 ′ connected to 3 2 for signal processing and control of image data from the capsule 3D, and a display device 4 connected to the control circuit 3 4 ′ for displaying images and the like 0 and an input circuit 41 for inputting a command or data to be transmitted to the capsule 3D.
- control circuit 34 has a function such as the signal processing circuit 35 of FIG. 1, the image position detection circuit 36, and the correction amount calculation circuit.
- the battery in the cubicle 3D and the battery on the external device 4D side are omitted.
- the capsule 3D swallowed by the patient has a built-in image sensor 8 composed of a CCD, a CMOS sensor, etc., and is connected to the image sensor 8 to illuminate the inside of a living body to be imaged by the image sensor 8.
- a lighting circuit 7 composed of a sushi ED or the like is provided.
- the illumination circuit 7 and the image sensor 8 are connected to an imaging drive control circuit 21 ′.
- the imaging drive / control circuit 21 ′ performs control such as acquisition of an image and transmission of an image to the wireless circuit 10.
- the capsule 3D is provided with an antenna 11 for transmitting and receiving, and receives a radio signal transmitted from the external device 4 and transmits image data to the external device 4D by radio.
- the antenna 11 is connected to the radio circuit 10 and demodulates a signal received by the antenna 11. Also, the signal to be transmitted is modulated and transmitted from the antenna 11 by radio waves.
- the radio circuit 10 is also connected to a memory (register) 25, which can store information on drug release and information on image acquisition.
- the capsule 3D is provided with a cylindrical medicine storage section 92 for storing a medicine, and a slidable cylinder is sent out by a cylinder feeder 94 so that the medicine is stored outside the capsule 3D.
- the drug can be released through the release valve 91.
- an extracorporeal device 4D that transmits and receives signals to and from the capsule 3D wirelessly includes an antenna 31 for transmission and reception, a wireless circuit 32, and a control circuit 34 '.
- control circuit 34 ' is connected to the display device 40, and the display device 40 displays an image of the inside of the body taken by the capsule 3D.
- the control circuit 34 ' is connected to the input circuit 41, and receives data to be sent to the capsule 3D.
- the input data is recorded by the control circuit 34 'and radiated by radio waves via the radio circuit 32 and the antenna 31.
- the data is transmitted via the antenna 11 and the radio circuit 10. Then, it is stored in the memory 25 or rewritten according to the demodulated and coded information.
- the imaging drive / control circuit 21 checks the information in the memory 25, executes the imaging when the imaging request is written to the memory 25, and transmits the image to the external device 4D via wireless.
- the transmitting external device 4D displays the image on the display device 40. Therefore, an operator (not shown) can acquire an image taken with the capsule 3D at any time.
- the shooting drive control circuit 21 'repeats the image acquisition operation until the shooting stop code is written in the memory 25.
- An operator (not shown) can confirm the image captured by the capsule 3D and perform an operation to start administration of the medicine.
- the operator inputs a command to open the drug release valve 91 from the input circuit 41.
- the input data is transmitted to the capsule 3D via the extracorporeal device 4D and stored in the memory 25.
- the administration controller 95 constantly monitors the information in the memory 25, and when the information for opening the drug release valve 91 is written in the memory 25, opens the drug release valve 91. Until the information for closing the drug release valve 91 is written into the memory 25, the administration control unit 95 keeps the drug release valve 91 open. Stay state.
- the operator inputs data indicating the feed speed of the cylinder feed device 94 from the input circuit 41.
- the input data is sent to the capsule 3D via the extracorporeal device 4D and stored in the memory 25.
- the administration control unit 95 constantly monitors the information in the memory 25. When the information on the re-transmission speed of the cylinder feeding device 94 is written in the memory 25, the data written in the cylinder feeding device 94 is written. Exercise at a speed based on the data. As a result, a drug (not shown) is pushed out of the capsule 3D via the drug release valve 91. Since the feed amount of the cylinder feeder 94 is specified, the amount of drug release per unit time can be controlled. The administration control unit 95 maintains the feed amount of the cylinder feed device 94 until information on the feed amount of the cylinder feed device 94 is newly written in the memory 25.
- the operator only needs to input data for reducing the feed rate of the cylinder feeder 94 when it is desired to reduce the amount of the drug released. What is necessary is just to input data for increasing the feeding speed of the feeding device 94, and it is possible to control the amount of drug release.
- the capsule 3D can be controlled only by writing desired data to the memory 25, and the capsule 3D side retains the information, thereby giving continuity to the operation. Therefore, communication between the capsule 3D and the extracorporeal device 4D can be simplified.
- the capsule 3D holds information, so that the continuation operation can be easily performed.
- the force-cell medical device of the present invention can easily change the setting state and operation of the built-in sensor and the like, and can easily change to a more appropriate operation and setting state. It can be applied to different applications.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Computer Networks & Wireless Communication (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Endoscopes (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Instruments For Viewing The Inside Of Hollow Bodies (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003292801A AU2003292801A1 (en) | 2003-05-29 | 2003-12-25 | Capsulized medical device |
EP03768225A EP1627592A4 (en) | 2003-05-29 | 2003-12-25 | CAPSULE MEDICAL DEVICE |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003152956A JP2004350963A (ja) | 2003-05-29 | 2003-05-29 | カプセル型医療装置 |
JP2003-152956 | 2003-05-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2004105590A1 true WO2004105590A1 (ja) | 2004-12-09 |
Family
ID=33447809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2003/016692 WO2004105590A1 (ja) | 2003-05-29 | 2003-12-25 | カプセル型医療装置 |
Country Status (5)
Country | Link |
---|---|
US (2) | US20040242962A1 (ja) |
EP (1) | EP1627592A4 (ja) |
JP (1) | JP2004350963A (ja) |
AU (1) | AU2003292801A1 (ja) |
WO (1) | WO2004105590A1 (ja) |
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Also Published As
Publication number | Publication date |
---|---|
JP2004350963A (ja) | 2004-12-16 |
AU2003292801A1 (en) | 2005-01-21 |
EP1627592A1 (en) | 2006-02-22 |
US20070073106A1 (en) | 2007-03-29 |
EP1627592A4 (en) | 2007-05-09 |
US20040242962A1 (en) | 2004-12-02 |
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