WO2002024140A2 - Distributeur doseur pour une matiere pulverulente ou particulaire deversable s'ecoulant librement - Google Patents

Distributeur doseur pour une matiere pulverulente ou particulaire deversable s'ecoulant librement Download PDF

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Publication number
WO2002024140A2
WO2002024140A2 PCT/EP2001/010688 EP0110688W WO0224140A2 WO 2002024140 A2 WO2002024140 A2 WO 2002024140A2 EP 0110688 W EP0110688 W EP 0110688W WO 0224140 A2 WO0224140 A2 WO 0224140A2
Authority
WO
WIPO (PCT)
Prior art keywords
dosing
metering
funnel
dosage
slide
Prior art date
Application number
PCT/EP2001/010688
Other languages
German (de)
English (en)
Other versions
WO2002024140A3 (fr
Inventor
Alwin Sobe
Original Assignee
Solvay Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals Gmbh filed Critical Solvay Pharmaceuticals Gmbh
Priority to AU2002221598A priority Critical patent/AU2002221598A1/en
Publication of WO2002024140A2 publication Critical patent/WO2002024140A2/fr
Publication of WO2002024140A3 publication Critical patent/WO2002024140A3/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/10—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation
    • G01F11/12—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements
    • G01F11/14—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber reciprocates
    • G01F11/18—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers moved during operation of the valve type, i.e. the separating being effected by fluid-tight or powder-tight movements wherein the measuring chamber reciprocates for fluent solid material

Definitions

  • the invention relates to a dosing dispenser for free-flowing, pourable powder or particulate material, in particular for particulate medicinal products, for simple dosing of small amounts of the material to be dosed in the 100 g range from storage containers.
  • Free-flowing and pourable, powdery and particulate goods of various types often have to be measured precisely from a storage container. This is particularly true for powdered, granular or pelletized drug formulations. Such pharmaceutical formulations are usually measured for use by means of so-called measuring or measuring spoons. For certain groups of people, e.g. B. in children or the elderly, or in stressful situations, with restlessness or nervousness, the exact dosing using measuring or measuring spoons may be difficult.
  • a metering dispenser of this type should be of simple construction, robust and, with simple handling, ensure comparable or even better metering than measuring or measuring spoons.
  • the invention is therefore based on the object of providing a simply constructed and easy-to-use metering dispenser which can be used instead of a measuring or sierlöffels can be combined with a storage container containing the goods to be dosed, and which allows safe dosing of free-flowing and pourable powder or particle-shaped goods.
  • the invention relates to a metering dispenser for a free-flowing and pourable powder or particulate material, which is contained in a storage vessel that can be manually tilted upside down, characterized by
  • a rotationally symmetrical cap (1) for attaching or screwing onto the neck of the storage vessel, the side opposite the cap opening (la) being designed as a funnel (lb);
  • a dosing body (2) comprising a dosing body housing for receiving a dosing slide (3), the dosing body housing
  • a) is firmly connected in the center to the funnel (lb) on the cover side (2a) facing the cap (1) and has an opening congruent with the mouth diameter of the funnel (lb) and
  • one vertically to the funnel (lb) laterally through the metering body housing in two fixed positions swinging metering slide (3), depending on the number of outlet openings in the bottom side (2b) of the metering body housing, has one or two metering chambers with a cross section corresponding to the cross section of the funnel (lb), with a metering chamber in the first position for covering with the mouth of the funnel (lb) and in the second position for covering can be brought with an outlet opening in the bottom side (2b) of the metering body housing;
  • a beak (4a) firmly connected to the bottom of the metering body and funnel-shaped to an outlet opening (4a) for the material to be metered.
  • the metering device according to the invention thus essentially consists of two funnels, which are formed by a metering body
  • the top funnel i. H. the cap (1) is designed as an inlet funnel with rotational symmetry and mediates the transition from the storage vessel to the metering device.
  • the lower funnel forms the outlet funnel as a beak (4), it is not rotationally symmetrical, its front and back are plane-parallel to one another , In its central position, the metering slide (3) closes the feed hopper and thus also the storage container with the free-flowing and pourable powder or particulate material. If desired, the metering slide is
  • the lock can, for. B. can be achieved by simple customary locking mechanisms on the metering body (2) and / or metering slide (3). Another simple way of fixing the metering slide (3) in the inlet and outlet positions is to equip the metering slide (3) with projecting head ends.
  • the metering dispenser according to the invention is preferably characterized in that the metering slide (3) has two metering mern (3a) and (3b), which can be operated alternately.
  • the cross section of the inlet and outlet openings and the metering chambers of the metering dispenser according to the invention can be elliptical or circular.
  • the cross section of the inlet and outlet openings and the metering chambers is preferably circular.
  • the dosing body (2) of the dosing dispenser according to the invention can be cuboidal, the corners and / or edges of the dosing body optionally being rounded.
  • the metering dispenser according to the invention is expediently suitable for a large number of storage vessels of different types and can easily be geometrically adapted to the respective individual case by a person skilled in the art while maintaining the design features according to the invention.
  • the field of use of the dispenser according to the invention is in particular in the pharmaceutical field, i. H. it is suitable, for example, for pharmaceutical containers that are usually used for the delivery of free-flowing and pourable powdered or particulate pharmaceuticals.
  • the dosing dispenser according to the invention is therefore particularly suitable for storage containers which are glass bottles for pharmaceutical purposes.
  • the dosing dispenser according to the invention can be used for a wide variety of free-flowing and pourable, powder and particle-shaped goods, in particular from the pharmaceutical sector.
  • the particulate goods can e.g. B. drug granules or drug pellets.
  • the dosing dispenser according to the invention is extremely suitable for so-called micropellets.
  • An example of an application for the dosing dispenser according to the invention is the pharmaceutical formulation Kreon® for children made of agro-resistant micropellets in a glass. Such micropellets are the enzyme substitution in z. B.
  • pancreatic insufficiency, digestive insufficiency after gastric surgery, liver and biliary disorders, cystic fibrosis or chronic pancreatitis are prescribed and are usually measured by measuring spoons or measuring spoons to application-related dosage units, which, however, cannot always ensure loss-free administration of the drug pellets, especially in small children.
  • the dosing dispenser according to the invention offers considerable relief, since an exact dosing can be ensured even if the child has to be held with one hand and the micropellets are to be dosed with the other hand.
  • the handling of the dispenser according to the invention is very simple. After opening the glass bottle (removing the screw cap or the cap), the dosing dispenser according to the invention is simply plugged or screwed onto the bottle neck, the dosing slide is brought into the filling position, ie to cover the cross section of the funnel (lb). The bottle is then placed briefly on the head and the metering slide is pushed into the dispensing position at the appropriate time, ie the cross section of the filled metering chamber is brought into line with the outlet opening on the bottom side (2b). The metered amount of pellet then collects in the funnel-shaped beak (4) and can be administered directly orally through the dispensing opening (4a).
  • Dosing dispensers that have two dosing chambers at a distance of one stroke length of the dosing slide and that can be operated alternately are particularly advantageous. This embodiment ensures that one of the two metering chambers (3a) and (3b) is always arranged in the filling position, so that a separate adjustment of the slide to the filling position can be dispensed with before use.
  • the dosing dispenser according to the invention can be provided for single use as well as preferably for multiple use.
  • Exemplary embodiments of the metering dispenser according to the invention are further explained by the figures and the example in their construction and operating principle. It is of course possible for the person skilled in the art to carry out routine modifications and adaptations, for example, within the framework of the design and operating principle.
  • the individual dimensions of the metering dispenser according to the invention can not only be adapted to the powder or particle parameters, but also to the type and dimension of the storage vessel.
  • the storage vessels can be plastic or metal containers and glass bottles.
  • the material from which the dosing dispenser according to the invention is constructed can be a plastic which is conventional per se and is compatible with foodstuffs or medicinal products.
  • the dosing dispenser according to the invention can be produced by means of the manufacturing techniques which are customary in plastics processing.
  • the metering device consists of a transparent plastic (for example made of acrylic glass) so that the metering processes can be followed optically.
  • Figure 1 Schematic representation of the metering device according to the invention. It means:
  • (1) rotationally symmetrical cap for attaching or screwing onto the neck of the storage vessel; with cap opening (la) and opposite side designed as a funnel (lb).
  • (3) metering slide; with two dosing chambers (3a) and (3b).
  • Figure 2 sectional views of the dosing device according to the invention (shown without cap (1)).
  • Fig. 2a dosing body (2) with beak (4) as Auslau judge.
  • the commercial product Kreon® for children is usually delivered with a small plastic measuring spoon enclosed. With the help of this spoon, the single doses of 100 mg, corresponding to 0.135 ml, are measured from the Kreon® pellets. The exact dosing of such a small volume with the measuring spoon proves difficult for some consumers.
  • the dosing can now alternatively be carried out by an easy-to-use dosing device or aid of the type according to the invention. This dosing device can be given to the consumer in addition to the dosing spoon, whereby multiple use is possible.
  • the dosing device according to the invention is simply plugged onto the Kreon glass bottle (RG 35/50) after removing the plastic stopper, and thus replaces the bottle's original closure.
  • the unit consisting of the metering device and the glass bottle is then rotated so that the bottom of the glass bottle points upwards.
  • the metering device - which is further illustrated by the figures - consists essentially of two funnels which are connected by a movable slide which contains the two metering chambers.
  • the upper funnel is rotationally symmetrical as an inlet funnel and mediates the transition from the glass bottle to the dosing device.
  • the lower funnel forms the discharge funnel, it is not rotationally symmetrical, its front and back are plane-parallel to each other.
  • the slide closes the inlet funnel and thus also the glass bottle with the Kreon pellets. If you move the slide to its right or left stop position, the metering chamber on the opposite side is filled with creon pellets.
  • the stop position is set, the measured amount of pellets runs out of the metering device via the discharge funnel. At the same time, the other dosing chamber is now filled. With each complete stroke from stop position to stop position, a single dose is portioned. If the removal is to be ended, it is sufficient to move the slide to the middle position. This closes the inlet funnel and the glass bottle again.
  • the metering device expediently consists of transparent plastic, for example of acrylic glass, so that the metering processes can also be followed optically.

Landscapes

  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Closures For Containers (AREA)

Abstract

Distributeur doseur présentant une structure et un maniement simples, adapté pour doser de petites quantités d'une matière pulvérulente ou particulaire déversable s'écoulant librement, en particulier d'un médicament particulaire, à partir d'un récipient de stockage. Le distributeur doseur selon la présente invention est par exemple avantageusement adapté pour doser de manière simple et à des fins pharmaceutiques des granules contenant un principe actif et contenus dans un flacon de verre, ce qui permet d'obtenir des doses individuelles. Le dispositif doseur selon la présente invention est constitué pour l'essentiel de deux entonnoirs qui sont reliés par l'intermédiaire d'un corps doseur à coulisseau de dosage mobile, qui possède une ou deux chambres de dosage. L'entonnoir supérieur qui peut être enfoncé ou vissé sur le récipient de stockage, au lieu du bouchon initial, établit le passage entre le récipient de stockage et le dispositif doseur, et se présente comme un entonnoir d'alimentation à symétrie de révolution. L'entonnoir inférieur constitue, en tant que bec, l'entonnoir de décharge qui n'est pas à symétrie de révolution, ses faces avant et arrière étant situées dans des plans parallèles. Ledit dispositif doseur peut être utilisé facultativement au lieu d'une cuiller de mesure ou de dosage classique et permet un dosage sûr de matière pulvérulente ou particulaire déversable s'écoulant librement, même dans la plage des 100 mg.
PCT/EP2001/010688 2000-09-20 2001-09-15 Distributeur doseur pour une matiere pulverulente ou particulaire deversable s'ecoulant librement WO2002024140A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002221598A AU2002221598A1 (en) 2000-09-20 2001-09-15 Dosage dispenser for a free-flowing, pourable pulverulent or particulate substance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2000146817 DE10046817A1 (de) 2000-09-20 2000-09-20 Dosierspender für freifließendes, schüttfähiges pulver- oder partikelförmiges Gut
DE10046817.9 2000-09-20

Publications (2)

Publication Number Publication Date
WO2002024140A2 true WO2002024140A2 (fr) 2002-03-28
WO2002024140A3 WO2002024140A3 (fr) 2002-09-12

Family

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PCT/EP2001/010688 WO2002024140A2 (fr) 2000-09-20 2001-09-15 Distributeur doseur pour une matiere pulverulente ou particulaire deversable s'ecoulant librement

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Country Link
AU (1) AU2002221598A1 (fr)
DE (1) DE10046817A1 (fr)
WO (1) WO2002024140A2 (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815072B2 (en) 2004-05-06 2010-10-19 Diversey, Inc. Metering and dispensing closure
GB2472217A (en) * 2009-07-28 2011-02-02 Pa Knowledge Ltd Dispenser with Sliding Seal
US7950550B2 (en) 2004-05-06 2011-05-31 Diversey, Inc. Metering and dispensing closure
US8245736B2 (en) 2009-04-28 2012-08-21 N.V. Nutricia Powder packaging
CN105600188A (zh) * 2016-02-02 2016-05-25 杨忠平 一种高精度计量的粉体喂料器
CN106081328A (zh) * 2016-08-22 2016-11-09 江苏光阳动力环保设备有限公司 一种防堵出料阀
CN108190066A (zh) * 2018-02-23 2018-06-22 北京恒安众生科技有限公司 颗粒制剂的调剂瓶头、调剂装置和调剂系统及调剂方法
CN110228668A (zh) * 2019-05-10 2019-09-13 杭州电子科技大学 一种粉末包装装置
CN110329560A (zh) * 2019-05-10 2019-10-15 杭州电子科技大学 一种粉末包装

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112405986B (zh) * 2021-01-22 2021-07-23 温州三星环保包装有限公司 一种基于植物纤维环保餐具制备的移动分料系统

Citations (6)

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US392911A (en) * 1888-11-13 Corn-planter attachment
GB215577A (en) * 1923-05-14 1924-05-15 Arthur Samuel Legg Improvements in and relating to apparatus for delivering measured quantities by volumes of pulverulent and other solid materials
DE3332528A1 (de) * 1983-09-09 1985-03-28 Walter Becker GmbH, 6605 Friedrichsthal Vorrichtung zum taktweisen dosieren von schuettfaehigem feststoff und von fluessigkeit in einem vorgegebenen verhaeltnis
US4733803A (en) * 1986-06-23 1988-03-29 Carnation Company Particulate dispensing apparatus
DE3817162A1 (de) * 1987-05-19 1988-12-01 Rhone Poulenc Agrochimie Vorrichtung zur verteilung von dosierten mengen granularer materialien
US5143126A (en) * 1990-01-29 1992-09-01 Ciba-Geigy Corporation Vibratory process and apparatus for agglomerating and metering non-flowable powders

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US3973704A (en) * 1975-05-23 1976-08-10 William Horowitz Self-contained measuring and dispensing device
IT8305052V0 (it) * 1983-11-08 1983-11-08 Meliconi Srl Dosatore per l'erogazione diprodotti granulari o in polvere
DE9011295U1 (fr) * 1990-08-01 1990-10-25 Boeckling, Klaus, 5430 Montabauer, De
DE4429328A1 (de) * 1994-08-18 1996-02-22 Pd Tech Produkte Dosiervorrichtung
DE29802035U1 (de) * 1998-02-06 1999-06-24 Roche Diagnostics Gmbh Dosierspender

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US392911A (en) * 1888-11-13 Corn-planter attachment
GB215577A (en) * 1923-05-14 1924-05-15 Arthur Samuel Legg Improvements in and relating to apparatus for delivering measured quantities by volumes of pulverulent and other solid materials
DE3332528A1 (de) * 1983-09-09 1985-03-28 Walter Becker GmbH, 6605 Friedrichsthal Vorrichtung zum taktweisen dosieren von schuettfaehigem feststoff und von fluessigkeit in einem vorgegebenen verhaeltnis
US4733803A (en) * 1986-06-23 1988-03-29 Carnation Company Particulate dispensing apparatus
DE3817162A1 (de) * 1987-05-19 1988-12-01 Rhone Poulenc Agrochimie Vorrichtung zur verteilung von dosierten mengen granularer materialien
US5143126A (en) * 1990-01-29 1992-09-01 Ciba-Geigy Corporation Vibratory process and apparatus for agglomerating and metering non-flowable powders

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8276790B2 (en) 2004-05-06 2012-10-02 Diversey, Inc. Metering and dispensing closure
US8833614B2 (en) 2004-05-06 2014-09-16 Diversey, Inc. Metering and dispensing closure
US7950550B2 (en) 2004-05-06 2011-05-31 Diversey, Inc. Metering and dispensing closure
US7815072B2 (en) 2004-05-06 2010-10-19 Diversey, Inc. Metering and dispensing closure
US8261951B2 (en) 2004-05-06 2012-09-11 Diversey, Inc. Metering and dispensing closure
US8245736B2 (en) 2009-04-28 2012-08-21 N.V. Nutricia Powder packaging
GB2472217A (en) * 2009-07-28 2011-02-02 Pa Knowledge Ltd Dispenser with Sliding Seal
CN105600188A (zh) * 2016-02-02 2016-05-25 杨忠平 一种高精度计量的粉体喂料器
CN106081328A (zh) * 2016-08-22 2016-11-09 江苏光阳动力环保设备有限公司 一种防堵出料阀
CN108190066A (zh) * 2018-02-23 2018-06-22 北京恒安众生科技有限公司 颗粒制剂的调剂瓶头、调剂装置和调剂系统及调剂方法
CN110228668A (zh) * 2019-05-10 2019-09-13 杭州电子科技大学 一种粉末包装装置
CN110329560A (zh) * 2019-05-10 2019-10-15 杭州电子科技大学 一种粉末包装
CN110228668B (zh) * 2019-05-10 2021-06-15 台州云界环境科技有限公司 一种粉末包装装置
CN110329560B (zh) * 2019-05-10 2021-09-28 苏州巴涛信息科技有限公司 一种粉末包装设备

Also Published As

Publication number Publication date
AU2002221598A1 (en) 2002-04-02
WO2002024140A3 (fr) 2002-09-12
DE10046817A1 (de) 2002-03-28

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