WO1999064480A1 - Novel ion exchange porous resins for solid phase extraction and chromatography - Google Patents

Novel ion exchange porous resins for solid phase extraction and chromatography Download PDF

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Publication number
WO1999064480A1
WO1999064480A1 PCT/US1999/013241 US9913241W WO9964480A1 WO 1999064480 A1 WO1999064480 A1 WO 1999064480A1 US 9913241 W US9913241 W US 9913241W WO 9964480 A1 WO9964480 A1 WO 9964480A1
Authority
WO
WIPO (PCT)
Prior art keywords
porous resin
group
vinylpyrrolidone
divinylbenzene
solute
Prior art date
Application number
PCT/US1999/013241
Other languages
English (en)
French (fr)
Inventor
Jeng-Jong Lee
John E. O'gara
Original Assignee
Waters Investments Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU44373/99A priority Critical patent/AU4437399A/en
Priority to DE69936920T priority patent/DE69936920T2/de
Priority to EP99927479A priority patent/EP1091981B1/en
Priority to US10/169,546 priority patent/US7232520B1/en
Priority to JP2000553484A priority patent/JP4883837B2/ja
Application filed by Waters Investments Limited filed Critical Waters Investments Limited
Publication of WO1999064480A1 publication Critical patent/WO1999064480A1/en
Priority to US10/782,397 priority patent/US7731844B2/en
Priority to US11/799,376 priority patent/US7442299B2/en
Priority to US12/259,199 priority patent/US7790038B2/en
Priority to US12/790,795 priority patent/US8197692B2/en
Priority to US12/855,300 priority patent/US8574433B2/en
Priority to US13/494,015 priority patent/US20120248033A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28042—Shaped bodies; Monolithic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3285—Coating or impregnation layers comprising different type of functional groups or interactions, e.g. different ligands in various parts of the sorbent, mixed mode, dual zone, bimodal, multimodal, ionic or hydrophobic, cationic or anionic, hydrophilic or hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/16—Organic material
    • B01J39/18—Macromolecular compounds
    • B01J39/20—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C08F8/24—Haloalkylation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C08F8/36—Sulfonation; Sulfation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/58—Use in a single column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/62—In a cartridge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/66—Other type of housings or containers not covered by B01J2220/58 - B01J2220/64
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/80—Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/82—Shaped bodies, e.g. monoliths, plugs, tubes, continuous beds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
PCT/US1999/013241 1998-06-12 1999-06-10 Novel ion exchange porous resins for solid phase extraction and chromatography WO1999064480A1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
AU44373/99A AU4437399A (en) 1998-06-12 1999-06-10 Novel ion exchange porous resins for solid phase extraction and chromatography
DE69936920T DE69936920T2 (de) 1998-06-12 1999-06-10 Neue poröse ionenaustauschharze für die festphasenextraktion und chromatographie
EP99927479A EP1091981B1 (en) 1998-06-12 1999-06-10 Novel ion exchange porous resins for solid phase extraction and chromatography
US10/169,546 US7232520B1 (en) 1998-06-12 1999-06-10 Ion exchange porous resins for solid phase extraction and chromatography
JP2000553484A JP4883837B2 (ja) 1998-06-12 1999-06-10 固相抽出及びクロマトグラフィー用の新規なイオン交換多孔質樹脂
US10/782,397 US7731844B2 (en) 1998-06-12 2004-02-18 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
US11/799,376 US7442299B2 (en) 1998-06-12 2007-05-01 Ion exchange porous resins for solid phase extraction and chromatography
US12/259,199 US7790038B2 (en) 1998-06-12 2008-10-27 Ion exchange porous resins for solid phase extraction and chromatography
US12/790,795 US8197692B2 (en) 1998-06-12 2010-05-28 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
US12/855,300 US8574433B2 (en) 1998-06-12 2010-08-12 Ion exchange porous resins for solid phase extraction and chromatography
US13/494,015 US20120248033A1 (en) 1998-06-12 2012-06-11 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8915398P 1998-06-12 1998-06-12
US60/089,153 1998-06-12

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10/169,546 A-371-Of-International US7232520B1 (en) 1998-06-12 1999-06-10 Ion exchange porous resins for solid phase extraction and chromatography
US10/782,397 Continuation-In-Part US7731844B2 (en) 1998-06-12 2004-02-18 Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
US11/799,376 Division US7442299B2 (en) 1998-06-12 2007-05-01 Ion exchange porous resins for solid phase extraction and chromatography

Publications (1)

Publication Number Publication Date
WO1999064480A1 true WO1999064480A1 (en) 1999-12-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/013241 WO1999064480A1 (en) 1998-06-12 1999-06-10 Novel ion exchange porous resins for solid phase extraction and chromatography

Country Status (6)

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US (7) US6322695B1 (US20100324159A1-20101223-C00002.png)
EP (1) EP1091981B1 (US20100324159A1-20101223-C00002.png)
JP (2) JP4883837B2 (US20100324159A1-20101223-C00002.png)
AU (1) AU4437399A (US20100324159A1-20101223-C00002.png)
DE (1) DE69936920T2 (US20100324159A1-20101223-C00002.png)
WO (1) WO1999064480A1 (US20100324159A1-20101223-C00002.png)

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EP1159995A2 (en) * 2000-06-02 2001-12-05 Showa Denko Kabushiki Kaisha Packing material for solid phase extraction and solid phase extraction method
WO2003102061A1 (en) * 2002-06-03 2003-12-11 Varian, Inc. A polymer with superior polar retention for sample pretreatment
WO2004065008A1 (en) * 2003-01-15 2004-08-05 V.I. Technologies, Inc. Methods for removing microbicidal compounds from compositions
WO2006106099A1 (fr) * 2005-04-06 2006-10-12 Rhodia Uk Limited Analyse améliorée d'anti-tartre polymères
WO2006118887A2 (en) * 2005-05-02 2006-11-09 Varian, Inc. Polar functionized polymer modified porous substrate for solid phase extraction
US7232520B1 (en) 1998-06-12 2007-06-19 Waters Investments Limited Ion exchange porous resins for solid phase extraction and chromatography
US7442299B2 (en) 1998-06-12 2008-10-28 Waters Investments Limited Ion exchange porous resins for solid phase extraction and chromatography
EP2233206A1 (en) 2009-03-24 2010-09-29 Symrise GmbH & Co. KG Flavor extracting device for isolation or analysis of volatile compounds
WO2011136329A1 (ja) * 2010-04-28 2011-11-03 株式会社日立ハイテクノロジーズ 吸着材及びその製造方法
US8101073B2 (en) 2004-08-31 2012-01-24 Shinwa Chemical Industries, Ltd. Separating agent for solid-phase extraction
WO2013002909A1 (en) 2011-05-20 2013-01-03 Waters Technologies Corporation Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
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US7045059B2 (en) * 2003-07-28 2006-05-16 Sielc Technologies Corp Universal bonded phase material for chromatographic separation
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US7731844B2 (en) 2010-06-08
US6322695B1 (en) 2001-11-27
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US20060021939A1 (en) 2006-02-02
US20100324159A1 (en) 2010-12-23
EP1091981B1 (en) 2007-08-22
US7790038B2 (en) 2010-09-07
DE69936920D1 (de) 2007-10-04
JP4883837B2 (ja) 2012-02-22
JP2002517574A (ja) 2002-06-18
US20070205156A1 (en) 2007-09-06
US8197692B2 (en) 2012-06-12
EP1091981A1 (en) 2001-04-18
DE69936920T2 (de) 2008-05-15
US20100300972A1 (en) 2010-12-02
US8574433B2 (en) 2013-11-05
US20090139323A1 (en) 2009-06-04
US7442299B2 (en) 2008-10-28
AU4437399A (en) 1999-12-30
EP1091981A4 (en) 2003-04-02
US20120248033A1 (en) 2012-10-04

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