UY39590A - Procedimiento para preparar 4-{4-[({[4-cloro-3- (trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n- metilpiridin-2-carboxamida, monohidrato y composiciones que lo comprenden - Google Patents

Procedimiento para preparar 4-{4-[({[4-cloro-3- (trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n- metilpiridin-2-carboxamida, monohidrato y composiciones que lo comprenden

Info

Publication number
UY39590A
UY39590A UY0001039590A UY39590A UY39590A UY 39590 A UY39590 A UY 39590A UY 0001039590 A UY0001039590 A UY 0001039590A UY 39590 A UY39590 A UY 39590A UY 39590 A UY39590 A UY 39590A
Authority
UY
Uruguay
Prior art keywords
amino
methylpyridine
carboxamide
monohydrate
carbonyl
Prior art date
Application number
UY0001039590A
Other languages
English (en)
Inventor
STIEHL Juprgen
Df Werner Heilmann
D Michael Logers
Dr Joachim Rehse
Dr Michael Gottfried
D Saskia WICHMANN
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44070712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY39590(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of UY39590A publication Critical patent/UY39590A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Abstract

La presente invención se refiere a un procedimiento para preparar 4-{4-[({[4- cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}-/\/-metilpiridin- 2-carboxamida, sus sales y monohidrato.
UY0001039590A 2010-04-15 2021-12-23 Procedimiento para preparar 4-{4-[({[4-cloro-3- (trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n- metilpiridin-2-carboxamida, monohidrato y composiciones que lo comprenden UY39590A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10004022 2010-04-15

Publications (1)

Publication Number Publication Date
UY39590A true UY39590A (es) 2022-01-31

Family

ID=44070712

Family Applications (2)

Application Number Title Priority Date Filing Date
UY0001033290A UY33290A (es) 2010-04-15 2011-03-24 Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n-metilpiridin-2-carboxamida, sus sales y monohidrato
UY0001039590A UY39590A (es) 2010-04-15 2021-12-23 Procedimiento para preparar 4-{4-[({[4-cloro-3- (trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n- metilpiridin-2-carboxamida, monohidrato y composiciones que lo comprenden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UY0001033290A UY33290A (es) 2010-04-15 2011-03-24 Procedimiento para preparar 4-{4-[({[4-cloro-3-(trifluorometil)fenil]amino}carbonil)amino]-3-fluorofenoxi}n-metilpiridin-2-carboxamida, sus sales y monohidrato

Country Status (39)

Country Link
US (5) US8748622B2 (es)
EP (1) EP2558448B1 (es)
JP (1) JP5934182B2 (es)
KR (2) KR101800041B1 (es)
CN (2) CN102947271B (es)
AR (2) AR081060A1 (es)
AU (1) AU2011240113B2 (es)
BR (1) BR112012026117B1 (es)
CA (1) CA2796238C (es)
CL (1) CL2012002840A1 (es)
CO (1) CO6630136A2 (es)
CR (1) CR20120526A (es)
CU (2) CU24123B1 (es)
DK (1) DK2558448T3 (es)
DO (2) DOP2012000268A (es)
EC (1) ECSP12012234A (es)
ES (1) ES2542610T3 (es)
GT (1) GT201200280A (es)
HK (1) HK1200831A1 (es)
HR (1) HRP20150885T1 (es)
HU (1) HUE026821T2 (es)
IL (2) IL222348B (es)
JO (1) JO3158B1 (es)
MA (1) MA34156B1 (es)
MX (1) MX2012011734A (es)
MY (2) MY177066A (es)
NZ (1) NZ602997A (es)
PE (2) PE20160838A1 (es)
PL (1) PL2558448T3 (es)
PT (1) PT2558448E (es)
RS (1) RS54219B1 (es)
RU (1) RU2581585C2 (es)
SG (2) SG10201501221UA (es)
SI (1) SI2558448T1 (es)
TN (1) TN2012000492A1 (es)
TW (2) TWI539951B (es)
UA (1) UA110613C2 (es)
UY (2) UY33290A (es)
WO (1) WO2011128261A1 (es)

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CN105330600B (zh) * 2015-11-30 2018-05-22 山东罗欣药业集团股份有限公司 一种瑞戈菲尼的制备方法
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Publication number Publication date
CL2012002840A1 (es) 2013-01-18
HUE026821T2 (en) 2016-07-28
MA34156B1 (fr) 2013-04-03
AU2011240113B2 (en) 2014-12-18
PE20130181A1 (es) 2013-02-23
KR20130061670A (ko) 2013-06-11
UY33290A (es) 2011-12-01
PT2558448E (pt) 2015-09-01
PL2558448T3 (pl) 2015-10-30
ES2542610T3 (es) 2015-08-07
EP2558448A1 (en) 2013-02-20
MY162359A (en) 2017-06-15
RU2581585C2 (ru) 2016-04-20
US20170057918A1 (en) 2017-03-02
BR112012026117A2 (pt) 2015-09-08
IL253119A0 (en) 2017-08-31
US10822305B2 (en) 2020-11-03
SG184172A1 (en) 2012-11-29
RU2012148386A (ru) 2014-05-20
AR081060A1 (es) 2012-06-06
KR20170129276A (ko) 2017-11-24
CU20140060A7 (es) 2014-10-02
CA2796238C (en) 2019-12-31
GT201200280A (es) 2014-07-23
IL222348B (en) 2018-08-30
TW201204356A (en) 2012-02-01
CR20120526A (es) 2013-03-11
JP2013523851A (ja) 2013-06-17
ECSP12012234A (es) 2012-11-30
PE20160838A1 (es) 2016-09-24
CO6630136A2 (es) 2013-03-01
US20130116442A1 (en) 2013-05-09
EP2558448B1 (en) 2015-05-20
CU24123B1 (es) 2015-08-27
DK2558448T3 (en) 2015-08-24
CU20120147A7 (es) 2013-01-30
IL253119B (en) 2018-03-29
JP5934182B2 (ja) 2016-06-15
TWI539951B (zh) 2016-07-01
HRP20150885T1 (hr) 2015-10-09
DOP2016000285A (es) 2016-11-30
UA110613C2 (uk) 2016-01-25
DOP2012000268A (es) 2012-12-15
TW201509415A (zh) 2015-03-16
US20170334857A1 (en) 2017-11-23
AR116395A2 (es) 2021-05-05
KR101800041B1 (ko) 2017-11-21
CN103980191A (zh) 2014-08-13
US8748622B2 (en) 2014-06-10
US20190144391A1 (en) 2019-05-16
SI2558448T1 (sl) 2015-11-30
MY177066A (en) 2020-09-03
US20140221661A1 (en) 2014-08-07
CN102947271B (zh) 2016-11-09
JO3158B1 (ar) 2017-09-20
US9458107B2 (en) 2016-10-04
AU2011240113A1 (en) 2012-10-11
BR112012026117B1 (pt) 2022-08-30
IL222348A0 (en) 2012-12-31
BR112012026117A8 (pt) 2017-12-19
MX2012011734A (es) 2012-12-17
TWI475992B (zh) 2015-03-11
NZ602997A (en) 2014-10-31
TN2012000492A1 (en) 2014-04-01
CA2796238A1 (en) 2011-10-20
HK1200831A1 (en) 2015-08-14
CN102947271A (zh) 2013-02-27
WO2011128261A1 (en) 2011-10-20
SG10201501221UA (en) 2015-04-29
RS54219B1 (en) 2015-12-31

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