BR112013009176A2 - processo para a síntese de álcoois quirais propargílicos. - Google Patents

processo para a síntese de álcoois quirais propargílicos.

Info

Publication number
BR112013009176A2
BR112013009176A2 BR112013009176A BR112013009176A BR112013009176A2 BR 112013009176 A2 BR112013009176 A2 BR 112013009176A2 BR 112013009176 A BR112013009176 A BR 112013009176A BR 112013009176 A BR112013009176 A BR 112013009176A BR 112013009176 A2 BR112013009176 A2 BR 112013009176A2
Authority
BR
Brazil
Prior art keywords
synthesis
propargyl
chiral alcohols
chiral
alcohols
Prior art date
Application number
BR112013009176A
Other languages
English (en)
Other versions
BR112013009176A8 (pt
Inventor
Aleksander Warm
Erick M Carreira
Lothar Zimmermann
Meinrad Brenner
Miriam Lorenzi
Nicka Chinkov
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of BR112013009176A2 publication Critical patent/BR112013009176A2/pt
Publication of BR112013009176A8 publication Critical patent/BR112013009176A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

processo para a síntese de álcoois quirais propargílicos. um processo para a síntese de álcoois quirais propargílicos.
BR112013009176A 2010-10-14 2011-10-14 processo para a síntese de álcoois propargílicos quirais BR112013009176A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39322110P 2010-10-14 2010-10-14
EP10013633A EP2447247A1 (en) 2010-10-14 2010-10-14 Process for the synthesis of chiral propargylic alcohols
PCT/EP2011/005164 WO2012048887A1 (en) 2010-10-14 2011-10-14 Process for the synthesis of chiral propargylic alcohols

Publications (2)

Publication Number Publication Date
BR112013009176A2 true BR112013009176A2 (pt) 2016-07-26
BR112013009176A8 BR112013009176A8 (pt) 2018-06-26

Family

ID=43709199

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013009176A BR112013009176A8 (pt) 2010-10-14 2011-10-14 processo para a síntese de álcoois propargílicos quirais

Country Status (9)

Country Link
US (2) US20130324763A1 (pt)
EP (2) EP2447247A1 (pt)
CN (1) CN103270017A (pt)
BR (1) BR112013009176A8 (pt)
EA (1) EA027477B1 (pt)
IL (1) IL225749A0 (pt)
TW (1) TW201223921A (pt)
WO (1) WO2012048887A1 (pt)
ZA (1) ZA201303010B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2441759A1 (en) 2010-10-14 2012-04-18 Lonza Ltd. Process for the synthesis of cyclic carbamates
EP2447255A1 (en) 2010-10-14 2012-05-02 Lonza Ltd. Process for the synthesis of cyclic carbamates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995020389A1 (en) 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
US5633405A (en) 1995-05-25 1997-05-27 Merck & Co., Inc. Asymmetric synthesis of (-)-6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxanzin-2-one
JP2000507970A (ja) 1997-01-10 2000-06-27 メルク エンド カンパニー インコーポレーテッド キラルメディエータの効率的な合成
TW432028B (en) 1997-01-14 2001-05-01 Merck & Co Inc Asymmetric conjugate addition reaction using a chiral additive
AR011731A1 (es) 1997-05-16 2000-08-30 Merck & Co Inc Un proceso de reaccion de adicion enantioselectiva eficiente utilizando un reactivo de organozinc.
DE102004009311A1 (de) * 2004-02-26 2005-09-08 Basf Ag Verfahren zur Herstellung eines Propargylalkohols und eines Allylalkohols
US8604189B2 (en) 2008-05-30 2013-12-10 Emcure Pharmaceuticals Limited Process for the preparation of Efavirenz

Also Published As

Publication number Publication date
IL225749A0 (en) 2013-06-27
ZA201303010B (en) 2014-10-29
EA027477B1 (ru) 2017-07-31
EA201390534A1 (ru) 2013-11-29
TW201223921A (en) 2012-06-16
US20160326101A1 (en) 2016-11-10
WO2012048887A1 (en) 2012-04-19
CN103270017A (zh) 2013-08-28
EP2627627B1 (en) 2017-08-09
US20130324763A1 (en) 2013-12-05
EP2627627A1 (en) 2013-08-21
BR112013009176A8 (pt) 2018-06-26
EP2447247A1 (en) 2012-05-02

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BRISTOL-MYERS SQUIBB COMPANY (US)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2483 DE 07-08-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]