UY38971A - Compuestos heterocíclicos como inhibidores de delta-5 desaturasa y métodos de uso - Google Patents

Compuestos heterocíclicos como inhibidores de delta-5 desaturasa y métodos de uso

Info

Publication number
UY38971A
UY38971A UY0001038971A UY38971A UY38971A UY 38971 A UY38971 A UY 38971A UY 0001038971 A UY0001038971 A UY 0001038971A UY 38971 A UY38971 A UY 38971A UY 38971 A UY38971 A UY 38971A
Authority
UY
Uruguay
Prior art keywords
compounds
delta
methods
heterocyclic compounds
desaturase inhibitors
Prior art date
Application number
UY0001038971A
Other languages
English (en)
Spanish (es)
Inventor
Elena Minatti Ana
Paul Bourbeau Matthew
Rebecca Allen Jennifer
Paolo Vincetti
Michela Beltrani
Teodora DAMYANOVA
Iain Lingard
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of UY38971A publication Critical patent/UY38971A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
UY0001038971A 2019-11-25 2020-11-25 Compuestos heterocíclicos como inhibidores de delta-5 desaturasa y métodos de uso UY38971A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962939821P 2019-11-25 2019-11-25

Publications (1)

Publication Number Publication Date
UY38971A true UY38971A (es) 2021-06-30

Family

ID=73855555

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038971A UY38971A (es) 2019-11-25 2020-11-25 Compuestos heterocíclicos como inhibidores de delta-5 desaturasa y métodos de uso

Country Status (21)

Country Link
US (3) US11512097B2 (https=)
EP (1) EP4065223A1 (https=)
JP (2) JP7254246B2 (https=)
KR (2) KR20230154292A (https=)
CN (2) CN114728167B (https=)
AR (1) AR120556A1 (https=)
AU (1) AU2020392087B2 (https=)
BR (1) BR112022010054A2 (https=)
CA (1) CA3162281A1 (https=)
CL (2) CL2022001357A1 (https=)
CO (1) CO2022008690A2 (https=)
CR (1) CR20220308A (https=)
IL (1) IL293191B2 (https=)
JO (1) JOP20220125A1 (https=)
MX (1) MX2022006281A (https=)
PE (1) PE20231097A1 (https=)
PH (1) PH12022551282A1 (https=)
SA (1) SA522432710B1 (https=)
TW (2) TWI815061B (https=)
UY (1) UY38971A (https=)
WO (1) WO2021108408A1 (https=)

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US11220510B2 (en) * 2018-04-09 2022-01-11 Incyte Corporation Pyrrole tricyclic compounds as A2A / A2B inhibitors
CN114728167B (zh) 2019-11-25 2024-03-19 安进公司 作为δ-5脱饱和酶抑制剂的杂环化合物以及使用方法
CN115557903A (zh) * 2022-09-27 2023-01-03 山东潍坊润丰化工股份有限公司 一种特草定的制备方法
CN120435293A (zh) 2022-11-23 2025-08-05 安进公司 选择使用fads-1抑制剂治疗fads1介导的疾病或障碍的患者

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Also Published As

Publication number Publication date
AU2020392087A1 (en) 2022-06-09
JP2022549739A (ja) 2022-11-28
JP7254246B2 (ja) 2023-04-07
TW202132317A (zh) 2021-09-01
TW202409042A (zh) 2024-03-01
CN114728167B (zh) 2024-03-19
KR20230154292A (ko) 2023-11-07
IL293191A (en) 2022-07-01
US20210221824A1 (en) 2021-07-22
KR102598203B1 (ko) 2023-11-03
JOP20220125A1 (ar) 2023-01-30
JP7698676B2 (ja) 2025-06-25
CL2022001357A1 (es) 2023-03-10
US20230159560A1 (en) 2023-05-25
US20210188874A1 (en) 2021-06-24
IL293191B2 (en) 2025-09-01
CO2022008690A2 (es) 2022-06-30
CN118161500A (zh) 2024-06-11
PH12022551282A1 (en) 2023-11-29
AR120556A1 (es) 2022-02-23
EP4065223A1 (en) 2022-10-05
US12448396B2 (en) 2025-10-21
JP2023078418A (ja) 2023-06-06
SA522432710B1 (ar) 2025-05-29
WO2021108408A1 (en) 2021-06-03
BR112022010054A2 (pt) 2022-08-16
TWI815061B (zh) 2023-09-11
TWI867822B (zh) 2024-12-21
MX2022006281A (es) 2022-06-08
CN114728167A (zh) 2022-07-08
US11512097B2 (en) 2022-11-29
AU2020392087B2 (en) 2025-10-23
CR20220308A (es) 2022-08-04
CL2023002486A1 (es) 2024-01-12
CA3162281A1 (en) 2021-06-03
IL293191B1 (en) 2025-05-01
KR20220106159A (ko) 2022-07-28
PE20231097A1 (es) 2023-07-18

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