UY38614A - Derivados de benzodiazepinas como inhibidores del rsv - Google Patents

Derivados de benzodiazepinas como inhibidores del rsv

Info

Publication number
UY38614A
UY38614A UY0001038614A UY38614A UY38614A UY 38614 A UY38614 A UY 38614A UY 0001038614 A UY0001038614 A UY 0001038614A UY 38614 A UY38614 A UY 38614A UY 38614 A UY38614 A UY 38614A
Authority
UY
Uruguay
Prior art keywords
present
rsv
compounds
benzodiazepine derivatives
rsv inhibitors
Prior art date
Application number
UY0001038614A
Other languages
English (en)
Inventor
Kaicheng Zhu
Kevin Mcgrath
Negretti-Emmanuelli Solymar
Adam Szymaniak
Jianming Yu
Jong Kim In
Sun Or Yat
Original Assignee
Enanta Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enanta Pharm Inc filed Critical Enanta Pharm Inc
Publication of UY38614A publication Critical patent/UY38614A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Abstract

La presente invención revela compuestos de Fórmula (I), o sales, ésteres o profármacos de uso farmacéutico aceptables de los mismos los cuales inhiben al Virus Respiratorio Sincicial (RSV) . La presente invención además se relaciona con composiciones farmacéuticas que comprenden los compuestos antes mencionados para administralos a un sujeto que padece de infección por RSV. La invención también se relaciona con los métodos de tratamiento de una infección por RSV en un sujeto mediante la administración de una composición farmacéutica que comprende los compuestos de la presente invención.
UY0001038614A 2019-03-18 2020-03-17 Derivados de benzodiazepinas como inhibidores del rsv UY38614A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962819915P 2019-03-18 2019-03-18
US201962821094P 2019-03-20 2019-03-20

Publications (1)

Publication Number Publication Date
UY38614A true UY38614A (es) 2020-10-30

Family

ID=72514103

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001038614A UY38614A (es) 2019-03-18 2020-03-17 Derivados de benzodiazepinas como inhibidores del rsv

Country Status (14)

Country Link
US (2) US11254664B2 (es)
EP (1) EP3941525A4 (es)
JP (1) JP2022525893A (es)
KR (1) KR20210138684A (es)
CN (1) CN113710276B (es)
AU (1) AU2020240024A1 (es)
BR (1) BR112021018335A2 (es)
CA (1) CA3133300A1 (es)
IL (1) IL286363A (es)
MX (1) MX2021011144A (es)
SG (1) SG11202110137VA (es)
TW (1) TW202102493A (es)
UY (1) UY38614A (es)
WO (1) WO2020190935A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113710276B (zh) * 2019-03-18 2024-03-29 英安塔制药有限公司 苯二氮䓬衍生物作为rsv抑制剂
GB201911944D0 (en) 2019-08-20 2019-10-02 Reviral Ltd Pharmaceutical compounds
GB201915273D0 (en) * 2019-10-22 2019-12-04 Reviral Ltd Pharmaceutical compounds

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Also Published As

Publication number Publication date
WO2020190935A1 (en) 2020-09-24
KR20210138684A (ko) 2021-11-19
TW202102493A (zh) 2021-01-16
JP2022525893A (ja) 2022-05-20
US20220227746A1 (en) 2022-07-21
AU2020240024A1 (en) 2021-10-14
CN113710276B (zh) 2024-03-29
IL286363A (en) 2021-10-31
CN113710276A (zh) 2021-11-26
EP3941525A1 (en) 2022-01-26
US20200299286A1 (en) 2020-09-24
US11254664B2 (en) 2022-02-22
BR112021018335A2 (pt) 2021-11-23
EP3941525A4 (en) 2022-12-07
US11912695B2 (en) 2024-02-27
CA3133300A1 (en) 2020-09-24
MX2021011144A (es) 2022-01-18
SG11202110137VA (en) 2021-10-28

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