US20040054417A1 - Disposable articulated spacing device for surgical treatment of joints of the human body - Google Patents
Disposable articulated spacing device for surgical treatment of joints of the human body Download PDFInfo
- Publication number
- US20040054417A1 US20040054417A1 US10/239,813 US23981303A US2004054417A1 US 20040054417 A1 US20040054417 A1 US 20040054417A1 US 23981303 A US23981303 A US 23981303A US 2004054417 A1 US2004054417 A1 US 2004054417A1
- Authority
- US
- United States
- Prior art keywords
- spacing device
- joint
- members
- formed members
- articulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000001356 surgical procedure Methods 0.000 title description 2
- 239000000463 material Substances 0.000 claims abstract description 19
- 238000002513 implantation Methods 0.000 claims abstract description 15
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 15
- 239000002639 bone cement Substances 0.000 claims abstract description 14
- 239000002184 metal Substances 0.000 claims abstract description 10
- 229910052751 metal Inorganic materials 0.000 claims abstract description 10
- 239000011148 porous material Substances 0.000 claims abstract description 10
- 239000004033 plastic Substances 0.000 claims abstract description 8
- 229920003023 plastic Polymers 0.000 claims abstract description 8
- 239000000919 ceramic Substances 0.000 claims abstract description 4
- 239000011521 glass Substances 0.000 claims abstract description 4
- 229910001092 metal group alloy Inorganic materials 0.000 claims abstract description 4
- 150000002739 metals Chemical class 0.000 claims abstract description 4
- 239000003242 anti bacterial agent Substances 0.000 claims description 8
- 229940088710 antibiotic agent Drugs 0.000 claims description 8
- 238000010521 absorption reaction Methods 0.000 claims description 4
- 238000004873 anchoring Methods 0.000 claims description 4
- 210000000629 knee joint Anatomy 0.000 claims description 4
- -1 polyethylene Polymers 0.000 claims description 4
- 229920000178 Acrylic resin Polymers 0.000 claims description 3
- 239000004925 Acrylic resin Substances 0.000 claims description 3
- 239000006193 liquid solution Substances 0.000 claims description 3
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000004743 Polypropylene Substances 0.000 claims description 2
- 238000000071 blow moulding Methods 0.000 claims description 2
- 210000003414 extremity Anatomy 0.000 claims description 2
- 238000001746 injection moulding Methods 0.000 claims description 2
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920001155 polypropylene Polymers 0.000 claims description 2
- 239000011347 resin Substances 0.000 claims description 2
- 229920005989 resin Polymers 0.000 claims description 2
- 229920001169 thermoplastic Polymers 0.000 claims description 2
- 239000007943 implant Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 210000001624 hip Anatomy 0.000 description 4
- 210000003127 knee Anatomy 0.000 description 4
- 230000003115 biocidal effect Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000005470 impregnation Methods 0.000 description 3
- 210000001503 joint Anatomy 0.000 description 3
- 239000000470 constituent Substances 0.000 description 2
- 210000002310 elbow joint Anatomy 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000004342 Benzoyl peroxide Substances 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 210000000474 heel Anatomy 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 230000005865 ionizing radiation Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30672—Features concerning an interaction with the environment or a particular use of the prosthesis temporary
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
Definitions
- the present invention is generally applicable to surgical treatment of articulations of the human body and in particular relates to a disposable spacing device for temporary replacement of joint prosthesis which have to be explanted due to unsuccessful septic or aseptic implantation of artificial joints.
- the above spacing device can be maintained in the joint seat as long as necessary for reestablishing the most favourable conditions of implantation of the new artificial joint prosthesis.
- Italian patent application No. VR95A000072 describes a disposable spacing device for an artificial hip joint, essentially characterized in that it is made of a biocompatible base material of the type used for bone cements.
- Spacing devices for knee joints which are manually made by the surgeon at the time of the surgical operation are also known, these devices being made from blocks of bone cement of standard shape, optionally containing active constituents.
- a drawback of these known methods of treatment is that they do not allow the space within the joint to be kept apart in an ergonomically and anatomically correct manner. Moreover, the long time required for preparation increases the difficulties for the surgeon and reduces the probability of success of the operation.
- spacing devices have been made using suitable anatomically and ergonomically shaped moulds which are filled with bone cement in situ.
- these known spacing devices do not allow mobilisation of the joint and result in the need for a long rehabilitation after reimplanting the permanent prosthesis.
- the spacing devices have been obtained by lining a permanent metal prosthesis with bone cement.
- this solution allows a temporary articulation, it is difficult to prepare and in spite of use of cement-lined prostheses requires that such devices are positioned in infected seats, which most of the surgeon consider a worsening infection factor.
- DE-A-29703971 discloses a temporary knee prosthesis comprising three pre-formed members made of bone cement and impregnated with an antibiotic agent, in accordance with the preamble of claim 1 .
- the antibiotic agent is added to the bone cement forming the members during their formation process and therefore the pre-formed members are initially impregnated with such medicaments.
- the surgeon has no freedom to choose the specific antibiotic or its amount which are more closely correlated to the particular patient.
- the prosthesis which is not a pharmaceutical product must nevertheless be packaged and stored in a suitable manner to comply with the requirements of the parmaceutical products.
- U.S. Pat. No. 5,980,573 relates to a temporary hip prosthesis comprising a single pre-formed member failing to provide a complete articulation joint.
- the base material of the prosthesis is impregnated with an antibiotic agent by simply-mixing it in appropriate amount with the constituent elements of the material during the formation process of the member.
- the pre-formed temporary prosthesis is pre-packaged in a sterile packet or container having indicia or colour coding indicating the size of the prosthesis contained therein and the antibiotic concentration, thereby excluding that impregnation is accomplished immediately prior of implantation.
- EP-A-0811359 teaches a method for manufacturing a material adapted for use as base material for prostheses, which material is formed by a three dimensional structure of band pieces joined together with the interposition of intermediate removable materials to form adjustable hollow spaces.
- the hollow spaces of the material may be filled with pharmaceutical or therapeutical active products such as antibiotics, hormones or growing agents.
- active products such as antibiotics, hormones or growing agents.
- the main object of the present invention is to provide surgeons with a disposable and ready-to-use articulated spacing device, able to be directly implanted in the articulation seat for example of knee, hip, hell or elbow joints, in case of replacement of a pre-existing prosthesis which must be removed due to septic or aseptic failures.
- a further object is to provide a disposable articulated spacing device which allows to maintain a in a healing environment a suitable articular space for the time necessary to successfully re-implant a new permanent prosthesis.
- a further object is to provide a disposable articulated spacing device which allows correct articulation and an anatomical and ergonomic form of the temporary implant.
- Yet another object is to provide a disposable articulated spacing device which can be easily implanted and explanted into/from the location of the joint.
- Yet another object is to provide a disposable articulated spacing device with limited articular friction so as to allow considerable mobility of the joint and improve the quality of life of the patient during hospitalisation.
- a disposable articulated spacing device for the temporary replacement of a joint of the human body which, in accordance with claim 1 , comprises at least one first member able to be secured to a first articulation end and at least one second member able to be secured to a second a articulation end, both said members being pre-formed and made entirely of biological compatible and porous material suitable to be added with pharmaceutical and therapeutical products, said pre-formed members being able to be reciprocally coupled in an articulated manner to maintain a suitable joint space and at least partial articulated mobility for the time necessary to perform the further implantation of a new permanent joint prosthesis, characterized in that said pre-formed members are initially free of pharmaceutical and therapeutical products, said pre-formed members having a porosity in their base material or suitable cavities formed on their outer surfaces adapted to be filled with pharmaceutical and therapeutical products in the form of liquid solutions added to the pre-formed members immediately prior of implantation thereof either by direct contact and absorption or by insertion thereof in said suitable
- the above mentioned biologically compatible and porous material is chosen among metals, metallic alloys, organo-metals, ceramics, glasses, plastics materials, bone cements and combinations thereof.
- the pre-formed members of the device may be previously charged with suitable pharmaceutical and therapeutical products.
- the pre-formed members are initially free of the same products and are added immediately prior of their implantation by contact absorption or by filling of suitable cavities formed on their other surface.
- the pharmaceutical and therapeutical products may be chosen among medical active principles, antibiotics and radiopacifier and may be added in the pre-formed members
- the pre-formed members may comprise a femoral member consisting of a body substantially shell-shaped and reproducing the femoral condyles, and tibial members consisting of a prismatic body able to replace the resected tibial flat portion.
- FIG. 1 shows a front view of a first detail of a spacing model according to the invention
- FIG. 2 shows a side view of the detail according to FIG. 1;
- FIG. 3 shows a top view of the detail according to FIG. 1;
- FIG. 4 shows a front view of another detail of the spacing device according to the invention.
- FIG. 5 shows a side view of the detail according to FIG. 4;
- FIG. 6 shows a top view of the detail according to FIG. 4;
- FIGS. 7 and 8 show perspective views, from the top and bottom, of the detail of the device illustrated in FIGS. 1 to 3 ;
- FIGS. 9 and 10 show a side view and a top perspective view of the detail according to FIGS. 4 to 6 ;
- FIG. 11 shows a perspective view of the two details of the preceding figures in aligned positions.
- FIG. 12 shows a side view of an alternative embodiment of the spacing device according to the invention.
- the articulated spacing device generally indicated with the reference number 1 , comprises at least one first member 2 able to be secured to a first joint end and at last one second member 3 able to be secured to a second joint end.
- both members 2 , 3 are pre-formed and entirely made of a biological compatible and porous material and are mutually coupled in an articulated manner so as to maintain in a healing environment a suitable joint space and at least partial mobility of the joint for the time necessary to permit the further re-implantation of a new permanent joint prosthesis.
- the biological compatible and porous material may be chosen among metals, metallic alloys organo-metals, ceramics, glasses, plastics materials and combinations thereof.
- the above plastics material may be chosen among thermoplastic polymers, such as acrylic resins, polyethylene, polypropylene, thermoformable e.g. by blow moulding or injection moulding.
- the plastics material may be chosen among cold-formable resins curable by means of free radical polymerisation such as acrylic resins and polyesters.
- free radical polymerisation may be accelerated either by suitable chemical catalysts and initiators, such as benzoyl peroxide, or physical accelerators such as ionizing radiation, gamma-rays, UV-rays.
- suitable chemical catalysts and initiators such as benzoyl peroxide, or physical accelerators such as ionizing radiation, gamma-rays, UV-rays.
- the biological compatible and porous material forming the members 2 , 3 is a bone-cements, e.g. that used in the Italian patent application no. VR95A000072 filed by the same applicant.
- the pre-formed members 2 , 3 may be previously added with suitable pharmaceutical and therapeutical products chosen among active medical principles, antibiotics and radiopacifiers.
- the pharmaceutical and therapeutical products may be added to the pre-formed members immediately prior of implantation thereof either by direct contact absorption or by filling of suitable cavities formed on their outer surfaces.
- the pharmaceutical and therapeutical products in the form of liquid solutions may be easily absorbed by the device thanks to the porosity of their basic material and then released after implantation in the joint seat.
- the pre-formed members 2 , 3 may be shaped in different sizes to be correctly adapted to the different patients. Moreover, these members may present anchoring means for their fixation to the joint ends.
- the embodiment of the spacer device 1 shown in the figures is designed to be inserted in the knee joint.
- the pre-formed member 2 is a tibial member and the pre-formed member 3 is a femoral member.
- the femoral part 3 consists of a first proximal body 4 designed to occupy the space left by an explanted metal prosthesis.
- the body 4 has a shape, in plan view, approximately in the form of a “U” or horseshoe, with side portions 4 ′, 4 ′′ and a central recess 5 .
- the external contact surface 6 of the body 4 has a curvature able to reproduce that of the femoral condyles.
- the tibial member 2 consists of a second proximal body 7 which is approximately prismatic, slightly curved and of suitable thickness.
- the body 7 also has a shape, in plan view, approximately in the form of a “U” or horseshoe, with a curved internal contact surface 8 and an internal recess 9 so as to simulate the resected tibial flat portion.
- the contact surfaces 6 , 8 of members 2 , 3 are formed so as to allow a roto-translatory movement during the flexing/extending movement of the limb.
- the surfaces 6 , 8 may have an excellent surface finish with a low coefficient of friction so as to allow a considerably degree of articular mobility.
- Both members 2 , 3 may be provided with respective projections or rod-shaped distal portions 10 , 11 for securing to the respective joint ends, e.g. by means of bone cement.
- the surgeon initially removes the previous infected joint prosthesis and cleans the articulation space.
- the surgeon further chooses the suitable spacing device with pre-formed members 2 , 3 adapted of the size of the patient.
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/963,123 US7601176B2 (en) | 2000-04-07 | 2004-10-12 | Disposable articulated spacing device for surgical treatment of joints of the human body |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2000VI000025U ITVI20000025U1 (it) | 2000-04-07 | 2000-04-07 | Dispositivo distanziatore temporaneo per il trattamento chirurgico del ginocchio |
ITVI2000U000025 | 2000-04-07 | ||
PCT/IB2001/000574 WO2001076512A1 (en) | 2000-04-07 | 2001-04-09 | Disposable articulated spacing device for surgical treatment of joints of the human body |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/963,123 Continuation US7601176B2 (en) | 2000-04-07 | 2004-10-12 | Disposable articulated spacing device for surgical treatment of joints of the human body |
Publications (1)
Publication Number | Publication Date |
---|---|
US20040054417A1 true US20040054417A1 (en) | 2004-03-18 |
Family
ID=11461146
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/239,813 Abandoned US20040054417A1 (en) | 2000-04-07 | 2001-04-09 | Disposable articulated spacing device for surgical treatment of joints of the human body |
US10/963,123 Expired - Lifetime US7601176B2 (en) | 2000-04-07 | 2004-10-12 | Disposable articulated spacing device for surgical treatment of joints of the human body |
US11/029,793 Abandoned US20050119756A1 (en) | 2000-04-07 | 2005-01-05 | Disposable articulated spacing device for surgical treatment of joints of the human body |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/963,123 Expired - Lifetime US7601176B2 (en) | 2000-04-07 | 2004-10-12 | Disposable articulated spacing device for surgical treatment of joints of the human body |
US11/029,793 Abandoned US20050119756A1 (en) | 2000-04-07 | 2005-01-05 | Disposable articulated spacing device for surgical treatment of joints of the human body |
Country Status (14)
Country | Link |
---|---|
US (3) | US20040054417A1 (ja) |
EP (2) | EP1952787A1 (ja) |
JP (2) | JP4491181B2 (ja) |
CN (1) | CN1216585C (ja) |
AT (1) | ATE416728T1 (ja) |
AU (1) | AU780792B2 (ja) |
CA (1) | CA2404771C (ja) |
DE (1) | DE60136920D1 (ja) |
DK (1) | DK1274374T3 (ja) |
ES (1) | ES2319100T3 (ja) |
IT (1) | ITVI20000025U1 (ja) |
MX (1) | MXPA02009918A (ja) |
PT (1) | PT1274374E (ja) |
WO (1) | WO2001076512A1 (ja) |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070150067A1 (en) * | 2005-12-27 | 2007-06-28 | Howmedica Osteonics Corp. | Hybrid femoral implant |
US20070233266A1 (en) * | 2006-03-20 | 2007-10-04 | Howmedica Osteonics Corp. | Composite joint implant |
US20100102484A1 (en) * | 2008-10-29 | 2010-04-29 | Sean Haney | Spacer molds with releasable securement |
US20100185298A1 (en) * | 2009-01-22 | 2010-07-22 | Stone Kenneth D | Acetabular Spacer for Treatment of Hip Sepsis |
US20100297276A1 (en) * | 2007-12-07 | 2010-11-25 | Zimmer, Inc. | Spacer Mold and Methods Therefor |
US20110118848A1 (en) * | 2008-08-06 | 2011-05-19 | Giovanni Faccioli | Modular spacer device for the treatment of prosthesis infections |
US20130060344A1 (en) * | 2011-09-07 | 2013-03-07 | Biomet Manufacturing Corp. | Femoral component with reinforced articulating surface |
US20140046452A1 (en) * | 2012-08-09 | 2014-02-13 | New York University | Total knee replacement substituting function of anterior cruciate ligament |
US8727203B2 (en) | 2010-09-16 | 2014-05-20 | Howmedica Osteonics Corp. | Methods for manufacturing porous orthopaedic implants |
US20140364954A1 (en) * | 2013-06-07 | 2014-12-11 | Gregory Merrell | Elbow antibiotic spacer implant |
US9622866B2 (en) | 2013-03-22 | 2017-04-18 | Heraeus Medical Gmbh | Two-component knee spacer with recesses |
US9622868B2 (en) | 2014-04-28 | 2017-04-18 | Biomet Manufacturing, Llc | Convertible pre-partial knee replacement |
US10022233B1 (en) * | 2017-12-04 | 2018-07-17 | Duke University | Orthopedic implant for sustained drug release |
US10265179B2 (en) | 2013-09-09 | 2019-04-23 | Cossington Limited | Adjustable modular spacer device for the articulation of the knee |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1418013B1 (en) | 2002-11-08 | 2005-01-19 | Howmedica Osteonics Corp. | Laser-produced porous surface |
US20060147332A1 (en) * | 2004-12-30 | 2006-07-06 | Howmedica Osteonics Corp. | Laser-produced porous structure |
DE602004002379T2 (de) * | 2004-03-30 | 2007-09-20 | Fin - Ceramica Faenza S.P.A. | Verfahren zur Herstellung von einer biologisch aktiven Prothesenvorrichtung zur Wiederherstellung von Knochengewebe und die Prothesenvorrichtung |
JP2006015042A (ja) * | 2004-07-05 | 2006-01-19 | Kazumasa Itokazu | 薬剤を含有する多孔体セラミックスペーサー |
WO2006110896A2 (en) * | 2005-04-12 | 2006-10-19 | The University Of Vermont And State Agriculture College | Knee prosthesis |
US8728387B2 (en) | 2005-12-06 | 2014-05-20 | Howmedica Osteonics Corp. | Laser-produced porous surface |
FR2898039B1 (fr) * | 2006-03-03 | 2008-06-27 | Ceravic Sas Soc Par Actions Si | Implant provisoire comprenant deux actifs. |
US7867426B2 (en) * | 2006-03-23 | 2011-01-11 | Ziran Bruce H | Method of forming a temporary implant |
US8147861B2 (en) * | 2006-08-15 | 2012-04-03 | Howmedica Osteonics Corp. | Antimicrobial implant |
US8142886B2 (en) | 2007-07-24 | 2012-03-27 | Howmedica Osteonics Corp. | Porous laser sintered articles |
US7842095B2 (en) * | 2007-09-11 | 2010-11-30 | Howmedica Osteonics Corp. | Antibiotic bone cement spacer |
WO2009108960A2 (en) * | 2008-02-25 | 2009-09-03 | Linares Medical Devices, Llc | Artificial wear resistant plug for mounting to existing joint bone |
DE102008040784B3 (de) * | 2008-07-28 | 2009-12-31 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Femurkomponente eines Kniegelenkspacers |
US8454706B2 (en) | 2009-02-25 | 2013-06-04 | Brian C. de Beaubien | Antibiotic delivery system and method for treating an infected synovial joint during re-implantation of an orthopedic prosthesis |
CA2706233C (en) * | 2009-06-04 | 2015-05-05 | Howmedica Osteonics Corp. | Orthopedic peek-on-polymer bearings |
DE202009012964U1 (de) | 2009-09-28 | 2010-03-18 | Medizinische Hochschule Hannover - Anstalt des öffentlichen Rechts | Gießform für einen Zementgroßkopf für die Hüftendoprothetik |
BR112013001673B1 (pt) | 2010-07-24 | 2021-02-09 | Zimmer, Inc | componentes de tíbia assimétrica para uma prótese de joelho |
WO2012018563A1 (en) | 2010-07-24 | 2012-02-09 | Zimmer, Inc. | Tibial prosthesis |
EP3348236B1 (en) | 2010-09-10 | 2019-11-20 | Zimmer, Inc. | Motion facilitating tibial components for a knee prosthesis |
US9597090B2 (en) | 2010-12-17 | 2017-03-21 | Zimmer, Inc. | Cut guide attachment for use in tibial prosthesis systems |
US8603101B2 (en) * | 2010-12-17 | 2013-12-10 | Zimmer, Inc. | Provisional tibial prosthesis system |
US9198759B2 (en) | 2011-09-19 | 2015-12-01 | Tecres S.P.A. | Modular spacer device for the treatment of infections of prosthesis of human limbs |
BR112014006485B1 (pt) * | 2011-09-19 | 2020-07-07 | Tecres S.P.A. | dispositivo espaçador modular para o tratamento de infecções de prótese de membros humanos |
MX337164B (es) * | 2011-09-19 | 2016-02-15 | Tecres Spa | Dispositivo separador modular temporal para las articulaciones del cuerpo humano. |
EP3372201B1 (en) | 2011-11-18 | 2020-05-20 | Zimmer, Inc. | Tibial bearing component for a knee prosthesis with improved articular characteristics |
EP2782525B1 (en) | 2011-11-21 | 2016-07-20 | Zimmer, Inc. | Tibial baseplate with asymmetric placement of fixation structures |
IN2014DN07145A (ja) | 2012-01-30 | 2015-04-24 | Zimmer Inc | |
US9364896B2 (en) | 2012-02-07 | 2016-06-14 | Medical Modeling Inc. | Fabrication of hybrid solid-porous medical implantable devices with electron beam melting technology |
US9180010B2 (en) | 2012-04-06 | 2015-11-10 | Howmedica Osteonics Corp. | Surface modified unit cell lattice structures for optimized secure freeform fabrication |
US9135374B2 (en) | 2012-04-06 | 2015-09-15 | Howmedica Osteonics Corp. | Surface modified unit cell lattice structures for optimized secure freeform fabrication |
FR2989568B1 (fr) * | 2012-04-19 | 2014-09-05 | Teknimed | Implant espaceur de remplacement temporaire d'une prothese de genou |
DE102013011296A1 (de) | 2013-07-08 | 2015-01-08 | Heraeus Medical Gmbh | Zweiteiliger artikulierender Gelenkspacer und Verfahren zu dessen Herstellung |
DE102013213831B4 (de) * | 2013-07-15 | 2015-01-29 | Heraeus Medical Gmbh | Kniespacer zum zeitweisen Ersetzen eines künstlichen Kniegelenks |
US9925052B2 (en) | 2013-08-30 | 2018-03-27 | Zimmer, Inc. | Method for optimizing implant designs |
WO2016046654A1 (en) * | 2014-09-23 | 2016-03-31 | Tecres S.P.A. | Constrained prosthesis for the knee joint |
US20170340445A1 (en) * | 2014-12-05 | 2017-11-30 | Ceramtec Gmbh | Ceramic Spacer for the Two-Sided Replacement of Implants in Shoulder, Knee and Hip as a Result of Infections |
FR3032347B1 (fr) * | 2015-02-05 | 2019-12-20 | Assistance Publique - Hopitaux De Paris | Prothese totale de genou avec couple de frottement ceramique sur ceramique et plateau mobile en ceramique. |
US10433965B2 (en) | 2015-06-17 | 2019-10-08 | Joint Purification Systems Llc | Total joint replacement infection control devices and methods |
WO2017053196A1 (en) | 2015-09-21 | 2017-03-30 | Zimmer, Inc. | Prosthesis system including tibial bearing component |
US10709564B2 (en) | 2015-10-07 | 2020-07-14 | Ceramtec Gmbh | Knee endoprosthesis for replacing at least parts of the knee joint |
CN110402123B (zh) | 2017-03-10 | 2022-02-08 | 捷迈有限公司 | 具有胫骨支承部件紧固特征的胫骨假体 |
CN110636818B (zh) | 2017-05-12 | 2021-06-04 | 捷迈有限公司 | 具有尺码增大和尺码缩小能力的股骨假体 |
US11298747B2 (en) | 2017-05-18 | 2022-04-12 | Howmedica Osteonics Corp. | High fatigue strength porous structure |
US11426282B2 (en) | 2017-11-16 | 2022-08-30 | Zimmer, Inc. | Implants for adding joint inclination to a knee arthroplasty |
US10835380B2 (en) | 2018-04-30 | 2020-11-17 | Zimmer, Inc. | Posterior stabilized prosthesis system |
IT201900012372A1 (it) | 2019-07-19 | 2021-01-19 | Tecres Spa | Dispositivo spaziatore per il controllo di disturbi o infezioni |
CN110721337A (zh) * | 2019-10-12 | 2020-01-24 | 上海交通大学医学院附属第九人民医院 | 一种锌基合金材料的用途和关节旷置假体及其制备方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4462120A (en) * | 1981-07-06 | 1984-07-31 | Andre Rambert | Total knee prosthesis |
US5123927A (en) * | 1990-12-05 | 1992-06-23 | University Of British Columbia | Method and apparatus for antibiotic knee prothesis |
US6027743A (en) * | 1994-06-03 | 2000-02-22 | Stryker Corporation | Manufacture of autogenous replacement body parts |
US6113640A (en) * | 1997-06-11 | 2000-09-05 | Bionx Implants Oy | Reconstructive bioabsorbable joint prosthesis |
US20010018614A1 (en) * | 1999-03-16 | 2001-08-30 | Bianchi John R. | Implants for orthopedic applications |
US20030033021A1 (en) * | 2001-07-16 | 2003-02-13 | Plouhar Pamela Lynn | Cartilage repair and regeneration scaffold and method |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5133755A (en) * | 1986-01-28 | 1992-07-28 | Thm Biomedical, Inc. | Method and apparatus for diodegradable, osteogenic, bone graft substitute device |
DE4033291A1 (de) * | 1990-10-19 | 1992-04-23 | Draenert Klaus | Werkstoff und verfahren zu seiner herstellung |
EP0523926A3 (en) * | 1991-07-15 | 1993-12-01 | Smith & Nephew Richards Inc | Prosthetic implants with bioabsorbable coating |
US5344459A (en) * | 1991-12-03 | 1994-09-06 | Swartz Stephen J | Arthroscopically implantable prosthesis |
DE4242889A1 (de) * | 1992-12-18 | 1994-06-23 | Merck Patent Gmbh | Hohlendoprothesen mit Knochenwachstumsfördernder Füllung |
US5522895A (en) * | 1993-07-23 | 1996-06-04 | Rice University | Biodegradable bone templates |
JP3333211B2 (ja) * | 1994-01-26 | 2002-10-15 | レイリー,マーク・エイ | 骨の治療に関する外科的方法で使用される、改良に係る拡張可能な装置 |
US5947893A (en) * | 1994-04-27 | 1999-09-07 | Board Of Regents, The University Of Texas System | Method of making a porous prothesis with biodegradable coatings |
DE69522060T2 (de) * | 1994-09-08 | 2002-05-29 | Stryker Technologies Corp | Bandscheibenkern aus Hydrogel |
DE4435680A1 (de) * | 1994-10-06 | 1996-04-11 | Merck Patent Gmbh | Poröse Knochenersatzmaterialien |
CA2160198C (en) * | 1994-10-27 | 2003-12-30 | Michael J. Pappas | Prosthesis fixturing device |
US5702458A (en) * | 1994-12-09 | 1997-12-30 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Joint prosthesis |
FI101933B1 (fi) * | 1995-06-13 | 1998-09-30 | Biocon Oy | Nivelproteesi |
JPH0930988A (ja) * | 1995-07-21 | 1997-02-04 | Sumitomo Osaka Cement Co Ltd | 薬剤徐放性多孔質セラミックス成形体及びその製造方法 |
IT1278853B1 (it) | 1995-09-08 | 1997-11-28 | Tecres Spa | Dispositivo distanziatore monouso per il trattamento delle artoprotesi dell'anca |
AU5596898A (en) * | 1996-12-03 | 1998-06-29 | Osteobiologics, Inc. | Biodegradable polymeric film |
DE29703971U1 (de) * | 1997-03-05 | 1998-07-09 | Siebel Thomas Dr | Knochenprothese |
DE69818456T2 (de) * | 1997-04-22 | 2004-07-29 | Washington Research Foundation, Seattle | Knochentransplantate und -prothesen beschichtet mit tartratbeständiger säurephosphatase |
US5980573A (en) * | 1997-05-12 | 1999-11-09 | Shaffner; Richard L. | Method and apparatus for fighting infection and maintaining joint spacing in a prosthesis implant area |
US6410044B1 (en) * | 1998-03-19 | 2002-06-25 | Surmodics, Inc. | Crosslinkable macromers |
US6129757A (en) * | 1998-05-18 | 2000-10-10 | Scimed Life Systems | Implantable members for receiving therapeutically useful compositions |
US6398814B1 (en) * | 1998-09-14 | 2002-06-04 | Bionx Implants Oy | Bioabsorbable two-dimensional multi-layer composite device and a method of manufacturing same |
US6419709B1 (en) * | 1998-10-02 | 2002-07-16 | Guilford Pharmaceuticals, Inc. | Biodegradable terephthalate polyester-poly(Phosphite) compositions, articles, and methods of using the same |
US20030114936A1 (en) * | 1998-10-12 | 2003-06-19 | Therics, Inc. | Complex three-dimensional composite scaffold resistant to delimination |
JP2002527144A (ja) * | 1998-10-12 | 2002-08-27 | セリックス, インコーポレイテッド | 組織再生のための複合体およびその製造方法 |
US6328765B1 (en) * | 1998-12-03 | 2001-12-11 | Gore Enterprise Holdings, Inc. | Methods and articles for regenerating living tissue |
US6206927B1 (en) * | 1999-04-02 | 2001-03-27 | Barry M. Fell | Surgically implantable knee prothesis |
US7338524B2 (en) * | 1999-05-10 | 2008-03-04 | Fell Barry M | Surgically implantable knee prosthesis |
US6419704B1 (en) * | 1999-10-08 | 2002-07-16 | Bret Ferree | Artificial intervertebral disc replacement methods and apparatus |
JP4172883B2 (ja) * | 1999-09-08 | 2008-10-29 | Hoya株式会社 | 薬物徐放用担体および薬物徐放用担体の製造方法 |
DK177997B1 (da) * | 2000-07-19 | 2015-02-23 | Ed Geistlich Söhne Ag Für Chemische Ind | Knoglemateriale og collagenkombination til opheling af beskadigede led |
AU2001285145A1 (en) * | 2000-08-21 | 2002-03-04 | Millennium Pharmaceuticals, Inc. | Human abc transporter family member and uses thereof |
US7335205B2 (en) * | 2001-03-02 | 2008-02-26 | Woodwelding Ag | Implants, device and method for joining tissue parts |
-
2000
- 2000-04-07 IT IT2000VI000025U patent/ITVI20000025U1/it unknown
-
2001
- 2001-04-09 WO PCT/IB2001/000574 patent/WO2001076512A1/en active IP Right Grant
- 2001-04-09 US US10/239,813 patent/US20040054417A1/en not_active Abandoned
- 2001-04-09 EP EP08006653A patent/EP1952787A1/en not_active Ceased
- 2001-04-09 JP JP2001574034A patent/JP4491181B2/ja not_active Expired - Fee Related
- 2001-04-09 AT AT01919693T patent/ATE416728T1/de active
- 2001-04-09 CA CA002404771A patent/CA2404771C/en not_active Expired - Fee Related
- 2001-04-09 DK DK01919693T patent/DK1274374T3/da active
- 2001-04-09 CN CN01807497.9A patent/CN1216585C/zh not_active Expired - Lifetime
- 2001-04-09 PT PT01919693T patent/PT1274374E/pt unknown
- 2001-04-09 DE DE60136920T patent/DE60136920D1/de not_active Expired - Lifetime
- 2001-04-09 ES ES01919693T patent/ES2319100T3/es not_active Expired - Lifetime
- 2001-04-09 MX MXPA02009918A patent/MXPA02009918A/es active IP Right Grant
- 2001-04-09 AU AU46752/01A patent/AU780792B2/en not_active Ceased
- 2001-04-09 EP EP01919693A patent/EP1274374B1/en not_active Expired - Lifetime
-
2004
- 2004-10-12 US US10/963,123 patent/US7601176B2/en not_active Expired - Lifetime
-
2005
- 2005-01-05 US US11/029,793 patent/US20050119756A1/en not_active Abandoned
-
2009
- 2009-12-10 JP JP2009280478A patent/JP5156727B2/ja not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4462120A (en) * | 1981-07-06 | 1984-07-31 | Andre Rambert | Total knee prosthesis |
US5123927A (en) * | 1990-12-05 | 1992-06-23 | University Of British Columbia | Method and apparatus for antibiotic knee prothesis |
US6027743A (en) * | 1994-06-03 | 2000-02-22 | Stryker Corporation | Manufacture of autogenous replacement body parts |
US6113640A (en) * | 1997-06-11 | 2000-09-05 | Bionx Implants Oy | Reconstructive bioabsorbable joint prosthesis |
US20010018614A1 (en) * | 1999-03-16 | 2001-08-30 | Bianchi John R. | Implants for orthopedic applications |
US20030033021A1 (en) * | 2001-07-16 | 2003-02-13 | Plouhar Pamela Lynn | Cartilage repair and regeneration scaffold and method |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070150067A1 (en) * | 2005-12-27 | 2007-06-28 | Howmedica Osteonics Corp. | Hybrid femoral implant |
US8070821B2 (en) | 2005-12-27 | 2011-12-06 | Howmedica Osteonics Corp. | Hybrid femoral implant |
US8333805B2 (en) | 2006-03-20 | 2012-12-18 | Howmedica Osteonics Corp. | Composite joint implant |
US20070233266A1 (en) * | 2006-03-20 | 2007-10-04 | Howmedica Osteonics Corp. | Composite joint implant |
US8801983B2 (en) | 2007-12-07 | 2014-08-12 | Zimmer Orthopaedic Surgical Products, Inc. | Spacer mold and methods therefor |
US20100297276A1 (en) * | 2007-12-07 | 2010-11-25 | Zimmer, Inc. | Spacer Mold and Methods Therefor |
US8480389B2 (en) | 2007-12-07 | 2013-07-09 | Zimmer Orthopedic Surgical Products, Inc. | Spacer mold and methods therefor |
US20150351919A1 (en) * | 2008-08-06 | 2015-12-10 | Tecres S.P.A. | Modular spacer device for the treatment of prosthesis infections |
US20110118848A1 (en) * | 2008-08-06 | 2011-05-19 | Giovanni Faccioli | Modular spacer device for the treatment of prosthesis infections |
US9795486B2 (en) * | 2008-08-06 | 2017-10-24 | Tecres S.P.A. | Modular spacer device for the treatment of prosthesis infections |
US9173742B2 (en) * | 2008-08-06 | 2015-11-03 | Tecres S.P.A. | Modular spacer device for the treatment of prosthesis infections |
US20100102484A1 (en) * | 2008-10-29 | 2010-04-29 | Sean Haney | Spacer molds with releasable securement |
US8414286B2 (en) | 2008-10-29 | 2013-04-09 | Zimmer Orthopaedic Surgical Products, Inc. | Spacer molds with releasable securement |
US10471638B2 (en) | 2008-10-29 | 2019-11-12 | Zimmer Orthopedic Surgical Products, Inc. | Spacer molds with releasable securement |
US8899959B2 (en) | 2008-10-29 | 2014-12-02 | Zimmer Orthopaedic Surgical Products, Inc. | Spacer molds with releasable securement |
US20100185298A1 (en) * | 2009-01-22 | 2010-07-22 | Stone Kenneth D | Acetabular Spacer for Treatment of Hip Sepsis |
US8727203B2 (en) | 2010-09-16 | 2014-05-20 | Howmedica Osteonics Corp. | Methods for manufacturing porous orthopaedic implants |
US20130060344A1 (en) * | 2011-09-07 | 2013-03-07 | Biomet Manufacturing Corp. | Femoral component with reinforced articulating surface |
US9023111B2 (en) * | 2012-08-09 | 2015-05-05 | New York University | Total knee replacement substituting function of anterior cruciate ligament |
US20140046452A1 (en) * | 2012-08-09 | 2014-02-13 | New York University | Total knee replacement substituting function of anterior cruciate ligament |
US9622866B2 (en) | 2013-03-22 | 2017-04-18 | Heraeus Medical Gmbh | Two-component knee spacer with recesses |
US9278002B2 (en) * | 2013-06-07 | 2016-03-08 | Gregory Merrell | Elbow antibiotic spacer implant |
US20140364954A1 (en) * | 2013-06-07 | 2014-12-11 | Gregory Merrell | Elbow antibiotic spacer implant |
US10265179B2 (en) | 2013-09-09 | 2019-04-23 | Cossington Limited | Adjustable modular spacer device for the articulation of the knee |
US9622868B2 (en) | 2014-04-28 | 2017-04-18 | Biomet Manufacturing, Llc | Convertible pre-partial knee replacement |
US10350076B2 (en) | 2014-04-28 | 2019-07-16 | Biomet Manufacturing, Llc | Convertible pre-partial knee replacement |
US10022233B1 (en) * | 2017-12-04 | 2018-07-17 | Duke University | Orthopedic implant for sustained drug release |
Also Published As
Publication number | Publication date |
---|---|
CN1440262A (zh) | 2003-09-03 |
US7601176B2 (en) | 2009-10-13 |
JP5156727B2 (ja) | 2013-03-06 |
WO2001076512A1 (en) | 2001-10-18 |
CN1216585C (zh) | 2005-08-31 |
JP2003529440A (ja) | 2003-10-07 |
JP4491181B2 (ja) | 2010-06-30 |
ITVI20000025U1 (it) | 2001-10-07 |
EP1274374A1 (en) | 2003-01-15 |
US20050085918A1 (en) | 2005-04-21 |
US20050119756A1 (en) | 2005-06-02 |
ATE416728T1 (de) | 2008-12-15 |
EP1274374B1 (en) | 2008-12-10 |
ES2319100T3 (es) | 2009-05-04 |
DE60136920D1 (de) | 2009-01-22 |
AU780792B2 (en) | 2005-04-14 |
MXPA02009918A (es) | 2004-09-06 |
AU4675201A (en) | 2001-10-23 |
EP1952787A1 (en) | 2008-08-06 |
PT1274374E (pt) | 2009-03-16 |
CA2404771A1 (en) | 2001-10-18 |
CA2404771C (en) | 2009-09-01 |
JP2010088921A (ja) | 2010-04-22 |
DK1274374T3 (da) | 2009-04-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2404771C (en) | Disposable articulated spacing device for surgical treatment of joints of the human body | |
US7427296B2 (en) | Total knee joint mold and methods | |
US7429346B2 (en) | Method of forming a temporary prosthetic joint using a disposable mold | |
US8388881B2 (en) | Method forming a one-piece articulating spacing device for a knee joint | |
KR102461337B1 (ko) | 무릎 관절을 위한 개선된 조절가능한 모듈형 스페이서 장치 | |
CA2545515A1 (en) | Tissue integration design for seamless implant fixation | |
CN105636553B (zh) | 用于膝关节的可调整的模块化间隔器装置 | |
US5980573A (en) | Method and apparatus for fighting infection and maintaining joint spacing in a prosthesis implant area | |
Schoellner et al. | Individual bone cement spacers (IBCS) for septic hip revision—preliminary report | |
CN103841923A (zh) | 用于人体的关节的临时模块式占位器装置 | |
CN111867520A (zh) | 用于人体关节的临时间隔件装置 | |
CN109640890B (zh) | 用于人体的关节的模块化间隔器装置 | |
RU174697U1 (ru) | Спейсер тазобедренного сустава | |
CN212186772U (zh) | 活动型占位器 | |
US11951012B2 (en) | Femoral element of knee spacer | |
US11344419B1 (en) | Total knee joint mold and methods for gap balancing and joint line restoration | |
CN214761627U (zh) | 力学性能好的金属钽制成的舟骨芯式假体 | |
RU146653U1 (ru) | Форма для интраоперационного изготовления вертлужного компонента спейсера тазобедренного сустава | |
RU2249438C1 (ru) | Способ пластики костного дефекта | |
CN111214314A (zh) | 活动型占位器 | |
JP2023139443A (ja) | 人工股関節ステムの構造および製造法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: TECRES S.P.A., ITALY Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SOFFIATI, RENZO;CASTELLI, CLAUDIO;FACCIOLI,GIOVANNI;REEL/FRAME:013179/0937 Effective date: 20021014 |
|
STCB | Information on status: application discontinuation |
Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION |