JP6419574B2 - 人間の肢体のプロテーゼの感染を処置するためのモジュール型スペーサ装置 - Google Patents
人間の肢体のプロテーゼの感染を処置するためのモジュール型スペーサ装置 Download PDFInfo
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
- A61F2002/30672—Features concerning an interaction with the environment or a particular use of the prosthesis temporary
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
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- A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/32—Joints for the hip
- A61F2/36—Femoral heads ; Femoral endoprostheses
- A61F2/3609—Femoral heads or necks; Connections of endoprosthetic heads or necks to endoprosthetic femoral shafts
- A61F2002/365—Connections of heads to necks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
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- A—HUMAN NECESSITIES
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00952—Coating, pre-coating or prosthesis-covering structure made of bone cement, e.g. pre-applied PMMA cement mantle
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Description
本発明は、たとえば股関節プロテーゼ、上腕プロテーゼ、膝プロテーゼ、および足首プロテーゼなどの関節プロテーゼの感染に対する二段階処置用のスペーサ装置に関する。
関節プロテーゼ感染は、関節プロテーゼにおける障害を引き起こす最も深刻な原因である。具体的に股関節の関節プロテーゼを参照すると、このような事象は、事例のうち0.5%から6%の間で変化する割合で頻繁に起こる。悪い事象の割合は、再移植の場合、または以前に行われた処置、局所的な血腫、介入性感染症、局所的もしくは全体的な骨疾患、および免疫抑制などの危険因子が存在することによって高まる。
本発明の目的は、先行技術を向上させることにある。
発明のさらなる特徴および利点は、添付の図面において例示される本発明の一部の実施形態についての記載からより明確となるであろう。
すなわち、相互結合面10,11は、スペーサ装置1の第1部分2および第2部分3の残りの部分が作られる材料と同じ材料で覆われる。
上述の相互結合面10,11は、より詳細には、ねじ10とナットねじ11とを含む。
本発明の他の局面によれば、スペーサ装置の第1部分2は、第2部分3が第1部分2に対して完全に緩められた位置を示す視覚表示部12を含む。
より特定的には、図8から図13は、異なる形状およびサイズの基部5に関する。
たとえば、アクリル骨セメント、またはシアノアクリレート接着剤、またはクロロホルム、メチルメタクリレート、酢酸エチル、ジクロロメタン、および多くの他のものなどの有機溶媒もしくは複数成分からなる混合物を使用することができる。
このような接着成分を施す段階は、特に、第2部分3のナットねじ11を接着成分で満たすことによって行われる。
したがって、この時間にわたって、第1部分2および第2部分3の結合面10,11の表面層が相互に溶接され、長時間にわたって固く、耐性を有し、安全な固定が得られる。
この実施形態は、第1部分2および第2部分3の結合面10,11の位置が逆であるという事実において、上述の実施形態とは異なる。
この実施形態においても、生体適合材料はポリメチルメタクリレートを含む。
Claims (24)
- 医薬品、活性物質および/もしくは治療成分を含むまたは加えられる生体適合材料からなる、人間の肢体のプロテーゼの感染に対する二段階処置用のスペーサ装置(1)であって、対応する骨層に固定されるように適合された第1部分(2)と、患者の対応する関節領域に挿入されるように適合された第2部分(3)とを備え、前記第1部分(2)と第2部分(3)とは調整可能な接合手段(4)によって接続され、前記接合手段(4)は、前記生体適合材料によって覆われた前記第1部分(2)および前記第2部分(3)のそれぞれに設けられた相互結合面(10,11)を含み、前記生体適合材料は、ポリメチルメタクリレートを含み、
前記相互結合面(10,11)は、ねじ(10)とナットねじ(11)とを含み、前記ねじ(10)および前記ナットねじ(11)は、丸みを帯びた形状のねじ切りを有するタイプからなる、スペーサ装置(1)。 - 前記第1部分(2)は、大腿部の近位部分に挿入される基部(5)を含む、請求項1に記載の装置。
- 前記基部(5)は、患者の大腿部の異なるサイズに適合するように異なる長さおよび断面を有し得る、請求項2に記載の装置。
- 前記第2部分(3)は、実質的に球形のヘッド(8)を含み、前記ヘッドは、患者の関節包の異なるサイズに適合するように、異なる寸法で設けられ、特に異なる球の径を有して設けられる、請求項1から3のいずれか1項に記載の装置。
- 前記第1部分(2)は、前記第2部分(3)を完全に緩めた位置の視覚表示部(12)を含む、請求項1から4のいずれか1項に記載の装置。
- 前記ねじ(10)は前記第1部分(2)に設けられ、前記ナットねじ(11)は前記第2部分(3)に設けられる、請求項1に記載の装置。
- 前記ねじ(10)は前記第2部分(3)に設けられ、前記ナットねじ(11)は前記第1部分(2)に設けられる、請求項1に記載の装置。
- 前記ねじ(10)は、前記球形のヘッド(8)に設けられる筒状の座部(13)内に設けられる、請求項7に記載の装置。
- 前記ねじ(10)には、前記ヘッド(8)に組み込まれる第2のコア(14)が設けられる、請求項7または8に記載の装置。
- 前記基部(5)には第1のコア(15)が設けられ、前記ナットねじ(11)は前記第1のコア(15)に設けられるハウジング(18)に挿入されるブッシング(17)を有して得られる、請求項7から9のいずれか1項に記載の装置。
- 位置調整可能な接合手段(4)を固定し、前記第1部分と前記第2部分との相互位置を固定するように適合された係止手段をさらに備える、請求項1から10のいずれか1項に記載の装置。
- 前記係止手段は、接着成分を付与することによって固く溶接された前記相互結合面(10,11)の部分を含む、請求項11に記載の装置。
- 前記接着成分はアクリル骨セメント、シアノアクリレート接着剤、またはクロロホルム、メチルメタクリレート、酢酸エチル、ジクロロメタンなどの有機溶媒もしくは複数の成分の混合物を含む、請求項12に記載の装置。
- 前記視覚表示部(12)は、前記ねじ(10)の外表面に沿って作られる帯を含む、請求項5に記載の装置。
- 前記基部(5)は、前記ナットねじ(11)が設けられる端部シャンク(16)を含む、請求項1から5または請求項7から10のいずれか1項に記載の装置。
- 前記基部(5)は、前記ナットねじ(11)が設けられる端部シャンク(16)を含み、
前記視覚表示部(12)は、前記端部シャンク(16)の外表面に沿って作られる帯を含む、請求項5に記載の装置。 - 前記基部(5)は、前記基部(5)を移植する大腿部の転節を保持するように実質的に円錐台形である、請求項1から16のいずれか1項に記載の装置。
- 前記生体適合材料は、装置に隣接する患者の組織に放出されるように適合された1つ以上の第1の医薬品、活性物質、および/もしくは治療成分を含む、請求項1から17のいずれか1項に記載の装置。
- 前記生体適合材料は、医薬品、活性物質および/もしくは治療成分を含まない、請求項1から18のいずれか1項に記載の装置。
- 前記生体適合材料は、多孔性であり、第1の医薬品、活性物質および/もしくは治療成分と同一または異なる1つ以上の医薬品、活性物質および/もしくは治療成分が含浸によって加えられる、請求項1から19のいずれか1項に記載の装置。
- 前記医薬品、活性物質および/もしくは治療成分は、抗生物質、ゲンタマイシン、バンコマイシン、防腐剤、抗真菌剤、化学治療物質、または他の活性成分のうち1つ以上を含む、請求項1から20のいずれか1項に記載の装置。
- 前記生体適合材料は、金属、金属合金、有機金属、セラミック、ガラス、およびプラスチックから選択される材料を含む、請求項1から10のいずれか1項に記載の装置。
- 前記生体適合材料は、熱可塑性ポリマー、全てのコポリマーおよびアクリル合金を含むアクリル樹脂、ポリエチレン、ポリプロピレンから選択されるプラスチックを含む、請求項1から10のいずれか1項に記載の装置。
- 前記プラスチックは、射出成形または吹込み成形によって熱成形可能である、請求項23に記載の装置。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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PCT/IB2011/054094 WO2013041906A1 (en) | 2011-09-19 | 2011-09-19 | Modular spacer device for the treatment of infections of the prosthesis of the human limbs |
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JP2014534830A JP2014534830A (ja) | 2014-12-25 |
JP6419574B2 true JP6419574B2 (ja) | 2018-11-07 |
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JP2014530326A Expired - Fee Related JP6419574B2 (ja) | 2011-09-19 | 2011-09-19 | 人間の肢体のプロテーゼの感染を処置するためのモジュール型スペーサ装置 |
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EP (1) | EP2758003B1 (ja) |
JP (1) | JP6419574B2 (ja) |
CN (1) | CN103857362B (ja) |
AR (1) | AR087003A1 (ja) |
AU (1) | AU2011377372B2 (ja) |
BR (1) | BR112014006485B1 (ja) |
CA (1) | CA2847610C (ja) |
ES (1) | ES2847857T3 (ja) |
MX (1) | MX349090B (ja) |
WO (1) | WO2013041906A1 (ja) |
Families Citing this family (12)
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JP6462694B2 (ja) * | 2013-09-09 | 2019-01-30 | コッシングトン リミテッド | 人体関節用の調節可能なモジュール式スペーサ装置 |
DE102013219656A1 (de) | 2013-09-27 | 2015-04-02 | Heraeus Medical Gmbh | Modulares Gelenkspacer-System |
BR112017010111A2 (pt) * | 2014-12-05 | 2017-12-26 | Ceram Gmbh | espaçador ("spacer") cerâmico para a troca bilateral de implantes em ombro, joelho e quadril como um resultado de infecções |
US10433965B2 (en) | 2015-06-17 | 2019-10-08 | Joint Purification Systems Llc | Total joint replacement infection control devices and methods |
CN106880420B (zh) * | 2015-12-16 | 2019-02-19 | 重庆润泽医药有限公司 | 一种仿生髋关节 |
CN106913402B (zh) * | 2015-12-25 | 2019-02-19 | 重庆润泽医药有限公司 | 一种组合式髋关节 |
ITUB20159789A1 (it) * | 2015-12-30 | 2017-06-30 | Tecres Spa | Anima per spaziatore |
ITUA20163046A1 (it) * | 2016-04-11 | 2017-10-11 | Augusto Magagnoli | dispositivo spaziatore modulare |
ITUA20163045A1 (it) * | 2016-04-11 | 2017-10-11 | Augusto Magagnoli | Dispositivo spaziatore per il trattamento di un'articolazione del corpo umano |
EP3384876A1 (en) * | 2017-04-07 | 2018-10-10 | Kyon AG | Total shoulder prosthesis |
CN110292469A (zh) * | 2019-06-25 | 2019-10-01 | 丁浩男 | 一种抗感染的医用临时假体 |
RU202061U1 (ru) * | 2020-04-09 | 2021-01-28 | Иван Михайлович Ефремов | Форма для изготовления головки монополярного спейсера тазобедренного сустава |
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2011
- 2011-09-19 EP EP11776023.1A patent/EP2758003B1/en active Active
- 2011-09-19 AU AU2011377372A patent/AU2011377372B2/en not_active Ceased
- 2011-09-19 ES ES11776023T patent/ES2847857T3/es active Active
- 2011-09-19 CA CA2847610A patent/CA2847610C/en not_active Expired - Fee Related
- 2011-09-19 CN CN201180073552.XA patent/CN103857362B/zh active Active
- 2011-09-19 JP JP2014530326A patent/JP6419574B2/ja not_active Expired - Fee Related
- 2011-09-19 BR BR112014006485-7A patent/BR112014006485B1/pt active IP Right Grant
- 2011-09-19 MX MX2014003356A patent/MX349090B/es active IP Right Grant
- 2011-09-19 WO PCT/IB2011/054094 patent/WO2013041906A1/en active Application Filing
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Also Published As
Publication number | Publication date |
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CN103857362A (zh) | 2014-06-11 |
EP2758003A1 (en) | 2014-07-30 |
BR112014006485B1 (pt) | 2020-07-07 |
WO2013041906A1 (en) | 2013-03-28 |
AU2011377372A1 (en) | 2014-04-03 |
MX2014003356A (es) | 2014-07-09 |
JP2014534830A (ja) | 2014-12-25 |
CA2847610C (en) | 2019-03-12 |
AR087003A1 (es) | 2014-02-05 |
BR112014006485A2 (pt) | 2017-04-04 |
CN103857362B (zh) | 2017-07-21 |
CA2847610A1 (en) | 2013-03-28 |
ES2847857T3 (es) | 2021-08-04 |
AU2011377372B2 (en) | 2016-10-06 |
MX349090B (es) | 2017-07-10 |
EP2758003B1 (en) | 2020-11-11 |
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