UA94923C2 - (1-aza-bicyclo[3.3.1] non-4-yl)-[5-(ih-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders - Google Patents
(1-aza-bicyclo[3.3.1] non-4-yl)-[5-(ih-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disordersInfo
- Publication number
- UA94923C2 UA94923C2 UAA200808018A UAA200808018A UA94923C2 UA 94923 C2 UA94923 C2 UA 94923C2 UA A200808018 A UAA200808018 A UA A200808018A UA A200808018 A UAA200808018 A UA A200808018A UA 94923 C2 UA94923 C2 UA 94923C2
- Authority
- UA
- Ukraine
- Prior art keywords
- psychotic
- treatment
- neurodegenerative disorders
- achr
- indol
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- Biomedical Technology (AREA)
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- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0525673.0A GB0525673D0 (en) | 2005-12-16 | 2005-12-16 | Organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
UA94923C2 true UA94923C2 (en) | 2011-06-25 |
Family
ID=35736291
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200808018A UA94923C2 (en) | 2005-12-16 | 2006-12-14 | (1-aza-bicyclo[3.3.1] non-4-yl)-[5-(ih-indol-5-yl)-heteroaryl]-amines as cholinergic ligands of the n-achr for the treatment of psychotic and neurodegenerative disorders |
Country Status (31)
Country | Link |
---|---|
US (3) | US7713977B2 (ru) |
EP (2) | EP2354141A1 (ru) |
JP (1) | JP4995203B2 (ru) |
KR (4) | KR20140097598A (ru) |
CN (1) | CN101305003B (ru) |
AT (1) | ATE531716T1 (ru) |
AU (1) | AU2006326257B2 (ru) |
BR (1) | BRPI0620003A2 (ru) |
CA (1) | CA2632893C (ru) |
CR (1) | CR9965A (ru) |
CY (1) | CY1112410T1 (ru) |
DK (1) | DK1966208T3 (ru) |
EC (1) | ECSP088486A (ru) |
ES (1) | ES2376647T3 (ru) |
GB (1) | GB0525673D0 (ru) |
GT (1) | GT200800096A (ru) |
HK (1) | HK1121443A1 (ru) |
HR (1) | HRP20120071T1 (ru) |
IL (1) | IL191054A (ru) |
MA (1) | MA30025B1 (ru) |
MY (1) | MY147369A (ru) |
NO (1) | NO20083145L (ru) |
NZ (1) | NZ568269A (ru) |
PL (1) | PL1966208T3 (ru) |
PT (1) | PT1966208E (ru) |
RU (1) | RU2440350C2 (ru) |
SI (1) | SI1966208T1 (ru) |
TN (1) | TNSN08257A1 (ru) |
UA (1) | UA94923C2 (ru) |
WO (1) | WO2007068475A1 (ru) |
ZA (1) | ZA200803408B (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6262265A (ja) * | 1985-09-13 | 1987-03-18 | Hitachi Ltd | 復水器自動検査補修システム |
GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
PE20060437A1 (es) * | 2004-06-18 | 2006-06-08 | Novartis Ag | COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR |
GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
GB0521508D0 (en) | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
WO2010056710A1 (en) * | 2008-11-11 | 2010-05-20 | Biovista, Inc. | Compositions and methods for treating eye diseases |
CN102573842A (zh) * | 2009-07-23 | 2012-07-11 | 诺瓦提斯公司 | 氮杂双环烷基衍生物或吡咯烷-2-酮衍生物的用途 |
TWI558398B (zh) | 2009-09-22 | 2016-11-21 | 諾華公司 | 菸鹼乙醯膽鹼受體α7活化劑之用途 |
US20140171448A1 (en) * | 2011-01-27 | 2014-06-19 | Novartis Ag | Use of nicotinic acetylcholine receptor alpha 7 activators |
CA2830458A1 (en) | 2011-03-18 | 2012-09-27 | Novartis Ag | Combinations of alpha 7 nicotinic acetylcholine receptor activators and mglur5 antagonists for use in dopamine induced dyskinesia in parkinson's disease |
JO3766B1 (ar) | 2011-10-20 | 2021-01-31 | Novartis Ag | منشط مستقبل أسيتيل كولين الفا - 7 النيكوتيني |
EP2931315B1 (en) | 2012-12-11 | 2017-11-29 | Novartis AG | Biomarker predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment |
BR112015016995B8 (pt) | 2013-01-15 | 2022-07-26 | Novartis Ag | Uso de agonistas do receptor alfa 7 nicotínico de acetilcolina |
US20150313884A1 (en) | 2013-01-15 | 2015-11-05 | Novartis Ag | Use of alpha 7 nicotinic acetylcholine receptor agonists |
EP2945626B1 (en) * | 2013-01-15 | 2018-09-12 | Novartis AG | Use of alpha 7 nicotinic receptor agonists for the treatment of narcolepsy |
BR112015016992A8 (pt) | 2013-01-15 | 2018-01-23 | Novartis Ag | uso de agonistas do receptor alfa 7 nicotínico de acetilcolina |
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BE759371A (fr) | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
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CA2002182C (en) | 1989-11-03 | 2000-06-13 | Richard J. Wurtman | Compositions for treating the premenstrual or late luteal phase syndrome and methods for their use |
YU84791A (sh) | 1990-05-19 | 1994-06-10 | Boehringer Ingelheim Kg. | Biciklicni 1-aza-cikloalkalni |
DE4116582A1 (de) | 1990-05-19 | 1991-11-21 | Boehringer Ingelheim Kg | Bicyclische 1-aza-cycloalkane |
JP2603879B2 (ja) | 1990-05-23 | 1997-04-23 | 富士重工業株式会社 | 多段自動変速機付4輪駆動車 |
KR930702312A (ko) * | 1990-08-31 | 1993-09-08 | 아만 히데아키 | 피리미딘 유도체 및 의약 |
JP3087763B2 (ja) | 1990-11-30 | 2000-09-11 | 三井化学株式会社 | 新規な複素環式化合物およびそれを含有する医薬組成物 |
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