UA84140C2 - Дисперсия кристаллов или гранул активного вещества с маскированным вкусом, жевательные мягкие капсулы, заполненные указанной дисперсией, и способ их приготовления - Google Patents
Дисперсия кристаллов или гранул активного вещества с маскированным вкусом, жевательные мягкие капсулы, заполненные указанной дисперсией, и способ их приготовленияInfo
- Publication number
- UA84140C2 UA84140C2 UAA200508284A UA2005008284A UA84140C2 UA 84140 C2 UA84140 C2 UA 84140C2 UA A200508284 A UAA200508284 A UA A200508284A UA 2005008284 A UA2005008284 A UA 2005008284A UA 84140 C2 UA84140 C2 UA 84140C2
- Authority
- UA
- Ukraine
- Prior art keywords
- dispersion
- granules
- crystals
- manufacturing
- active substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
Данное изобретение относится к дисперсии кристаллов или гранул активного вещества в липофильном наполнителе, на указанные кристаллы или гранулы наносят покрытие для маскировки вкуса. Изобретение также касается стандартных лекарственных форм и, преимущественно, жевательных или мягких желатиновых капсул, которые быстро растворяются, заполненных указанной дисперсией, а также к способу производства таких форм.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0300824A FR2850275B1 (fr) | 2003-01-24 | 2003-01-24 | Capsules molles a macher contenant une substance active a gout masque |
PCT/US2004/001463 WO2004066925A2 (en) | 2003-01-24 | 2004-01-21 | Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same |
Publications (1)
Publication Number | Publication Date |
---|---|
UA84140C2 true UA84140C2 (ru) | 2008-09-25 |
Family
ID=32669215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UAA200508284A UA84140C2 (ru) | 2003-01-24 | 2004-01-21 | Дисперсия кристаллов или гранул активного вещества с маскированным вкусом, жевательные мягкие капсулы, заполненные указанной дисперсией, и способ их приготовления |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP1592402B1 (ru) |
JP (1) | JP5371187B2 (ru) |
CN (2) | CN1741787A (ru) |
AR (1) | AR042902A1 (ru) |
AU (1) | AU2004207498B2 (ru) |
BR (1) | BRPI0406913B8 (ru) |
CA (1) | CA2512988C (ru) |
DK (1) | DK1592402T3 (ru) |
ES (1) | ES2415660T3 (ru) |
FR (1) | FR2850275B1 (ru) |
HK (1) | HK1082659A1 (ru) |
MX (1) | MXPA05007683A (ru) |
NO (1) | NO339528B1 (ru) |
NZ (1) | NZ541753A (ru) |
PT (1) | PT1592402E (ru) |
RU (1) | RU2362546C2 (ru) |
SI (1) | SI1592402T1 (ru) |
UA (1) | UA84140C2 (ru) |
WO (1) | WO2004066925A2 (ru) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005013944A1 (en) * | 2003-08-11 | 2005-02-17 | Merck Frosst Canada Ltd. | Flavored taste-masked pharmaceutical formulation made using a one-step coating process |
US7169385B2 (en) | 2003-09-29 | 2007-01-30 | Ronald G. Udell | Solubilized CoQ-10 and carnitine |
EP1670325A1 (en) | 2003-09-29 | 2006-06-21 | Soft Gel Technologies, Inc. | SOLUBILIZED CoQ-10 |
US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
US20080020022A1 (en) * | 2006-06-05 | 2008-01-24 | Udell Ronald G | Chewable co-enzyme q-10 capsule |
US20070292501A1 (en) * | 2006-06-05 | 2007-12-20 | Udell Ronald G | Chewable soft gelatin capsules |
US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
MX339727B (es) * | 2007-07-19 | 2016-06-06 | R-Tech Ueno Ltd | Composicion farmaceutica que comprende un compuesto de 11-desoxi-prostaglandina y metodo para estabilizar el compuesto. |
FR2935084B1 (fr) * | 2008-08-19 | 2011-05-06 | Pancosma Sa Pour L Ind Des Produits Biochimiques | Additif pour l'alimentation animale et son procede de preparation |
GB201006218D0 (en) * | 2010-04-14 | 2010-06-02 | Ayanda As | Composition |
CA3065589C (en) | 2010-06-03 | 2022-04-26 | Catalent Ontario Limited | Multi phase soft gel capsules, apparatus and method thereof |
CA2706270C (en) * | 2010-06-03 | 2020-01-07 | Accucaps Industries Limited | Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation |
WO2012108738A2 (ko) * | 2011-02-11 | 2012-08-16 | 주식회사 씨티씨바이오 | 실데나필 유리염기 함유 필름 제제 및 이의 제조 방법 |
CA3023121A1 (en) * | 2011-04-11 | 2012-10-18 | Vitux Group As | Oral pharmaceutical dispersion compositions |
US20140044779A1 (en) * | 2011-04-18 | 2014-02-13 | Lipidor Ab | Liquid Carrier for Oral Delivery of a Pharmacologically Active Agent |
CN102241782B (zh) * | 2011-05-18 | 2013-01-30 | 清华大学 | 一种淀粉乙酸酯的制备方法及其在去除水中硝酸盐的应用 |
CN102813275B (zh) | 2011-06-10 | 2015-09-30 | 杭州养生堂保健品有限公司 | 一种咀嚼型软胶囊皮和咀嚼型软胶囊 |
DE102012014848A1 (de) * | 2012-07-27 | 2012-10-31 | Heilerde-Gesellschaft Luvos Just GmbH & Co. KG | Heilerde-Zubereitung |
US20150209360A1 (en) * | 2014-01-30 | 2015-07-30 | Orbz, Llc | Oral caffeine delivery composition |
FR3027802B1 (fr) | 2014-10-31 | 2018-03-02 | Ethypharm | Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant |
ES2787220T3 (es) | 2015-03-26 | 2020-10-15 | Patheon Softgels Inc | Cápsulas blandas llenas de líquido |
SI3429559T1 (sl) * | 2016-03-15 | 2022-11-30 | Acer Therapeutics Inc. | Okusni sestavki, ki vključujejo natrijev fenilbutirat, in njihove uporabe |
JP6942342B2 (ja) * | 2016-11-02 | 2021-09-29 | 富士カプセル株式会社 | ソフトカプセル皮膜 |
JP2018121699A (ja) * | 2017-01-30 | 2018-08-09 | 株式会社アクレス | クリルオイルを充填したカプセル剤 |
CN107373744B (zh) * | 2017-07-13 | 2018-11-09 | 云南中烟工业有限责任公司 | 一种维生素c微胶囊的制备方法及其在卷烟中的应用 |
CN108524464A (zh) * | 2018-05-17 | 2018-09-14 | 安士制药(中山)有限公司 | 一种西甲硅油软胶囊的制备方法 |
CN113490486A (zh) * | 2019-02-22 | 2021-10-08 | 康特伦英国斯温顿捷迪斯有限公司 | 最小化团聚、曝气和保持包含布洛芬的药物组合物的包衣 |
AR118159A1 (es) | 2019-02-22 | 2021-09-22 | Catalent Uk Swindon Zydis Ltd | Minimización de aglomeración, aireación y conservación del revestimiento de composiciones farmacéuticas que comprenden ibuprofeno |
MX2021009845A (es) * | 2019-02-22 | 2021-09-10 | Catalent Uk Swindon Zydis Ltd | Minimizacion de la aglomeracion de material de revestimiento de particula de medicamento durante el almacenaje para estabilizar los tiempos de desintegracion de productos farmaceuticos. |
JP2023549381A (ja) | 2020-11-18 | 2023-11-24 | バイオファーマ・シナジーズ,エス.エル. | 抗ヒスタミン活性化合物を含む口内分散性粉末組成物 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8623557D0 (en) | 1986-10-01 | 1986-11-05 | Boots Co Plc | Therapeutic agents |
US4851226A (en) * | 1987-11-16 | 1989-07-25 | Mcneil Consumer Products Company | Chewable medicament tablet containing means for taste masking |
GB8813682D0 (en) * | 1988-06-09 | 1988-07-13 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions |
CH677606A5 (ru) | 1988-07-12 | 1991-06-14 | Aesculapius Pharma Sa | |
US4975465A (en) | 1989-03-28 | 1990-12-04 | American Home Products Corporation | Orally administrable ibuprofen compositions |
CA2063141C (en) * | 1989-08-04 | 1997-03-04 | Edward J. Roche | Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets |
US5262179A (en) | 1989-09-13 | 1993-11-16 | Nicholas Kiwi Pty Ltd. | Non-effervescent ibuprofen compositions |
JPH05506011A (ja) | 1990-04-11 | 1993-09-02 | ジ・アップジョン・カンパニー | 流動床コーティングによるイブプロフェンの味覚マスキング |
JP3157233B2 (ja) * | 1991-11-22 | 2001-04-16 | エーザイ株式会社 | 水溶性薬物を含有した軟カプセル剤 |
JP3136310B2 (ja) * | 1992-02-26 | 2001-02-19 | 東洋カプセル株式会社 | 咀嚼服用に適した担体 |
IT1256022B (it) * | 1992-06-08 | 1995-11-20 | Preparazioni farmaceutiche stabili di nicorandil | |
MX9306393A (es) * | 1992-10-16 | 1994-04-29 | Glaxo Group Ltd | Composiciones de ranitidina substancialmente libres de sabor amargo, proceso para su preparacion y composiciones farmaceuticas que las contienen. |
GB9313329D0 (en) * | 1993-06-28 | 1993-08-11 | Scherer Ltd R P | Softgel capsule shell compositions |
US5466865A (en) | 1993-07-02 | 1995-11-14 | Ibah, Inc. | Neomorphic ibuprofen and methods of using same |
ZA945944B (en) | 1993-08-13 | 1996-02-08 | Eurand America Inc | Procedure for encapsulating nsaids |
US5569466A (en) * | 1995-05-17 | 1996-10-29 | R. P. Scherer Corporation | Fill compositions for soft elastic gel capsules |
US6024980A (en) * | 1996-06-28 | 2000-02-15 | Mcneil-Ppc, Inc. | Multiphase soft gelatin dosage form |
FR2785539B1 (fr) * | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Particules enrobees d'ibuprofene cristallin granule |
CA2363842C (en) * | 1999-02-26 | 2006-01-10 | Shionogi & Co., Ltd. | Chewable soft capsule having improved ingestion property and method for producing the same |
FR2795962B1 (fr) | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
CA2447693A1 (en) * | 2001-05-31 | 2002-12-05 | Cima Labs Inc. | Taste-masking of highly water-soluble drugs |
-
2003
- 2003-01-24 FR FR0300824A patent/FR2850275B1/fr not_active Expired - Lifetime
-
2004
- 2004-01-21 EP EP04704035A patent/EP1592402B1/en not_active Expired - Lifetime
- 2004-01-21 MX MXPA05007683A patent/MXPA05007683A/es active IP Right Grant
- 2004-01-21 CA CA2512988A patent/CA2512988C/en not_active Expired - Lifetime
- 2004-01-21 NZ NZ541753A patent/NZ541753A/en not_active IP Right Cessation
- 2004-01-21 RU RU2005126729/15A patent/RU2362546C2/ru active
- 2004-01-21 CN CNA2004800026701A patent/CN1741787A/zh active Pending
- 2004-01-21 PT PT47040357T patent/PT1592402E/pt unknown
- 2004-01-21 DK DK04704035.7T patent/DK1592402T3/da active
- 2004-01-21 CN CN2013100519606A patent/CN103169655A/zh active Pending
- 2004-01-21 AU AU2004207498A patent/AU2004207498B2/en not_active Expired
- 2004-01-21 WO PCT/US2004/001463 patent/WO2004066925A2/en active Application Filing
- 2004-01-21 UA UAA200508284A patent/UA84140C2/ru unknown
- 2004-01-21 SI SI200432050T patent/SI1592402T1/sl unknown
- 2004-01-21 BR BRPI0406913A patent/BRPI0406913B8/pt active IP Right Grant
- 2004-01-21 JP JP2006502898A patent/JP5371187B2/ja not_active Expired - Lifetime
- 2004-01-21 ES ES04704035T patent/ES2415660T3/es not_active Expired - Lifetime
- 2004-01-23 AR ARP040100180A patent/AR042902A1/es not_active Application Discontinuation
-
2005
- 2005-07-29 NO NO20053681A patent/NO339528B1/no not_active IP Right Cessation
- 2005-12-22 HK HK05111911.8A patent/HK1082659A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2415660T3 (es) | 2013-07-26 |
EP1592402B1 (en) | 2013-03-20 |
NO20053681L (no) | 2005-08-23 |
WO2004066925A3 (en) | 2004-10-28 |
AU2004207498B2 (en) | 2008-10-30 |
WO2004066925A2 (en) | 2004-08-12 |
NO339528B1 (no) | 2016-12-27 |
EP1592402A2 (en) | 2005-11-09 |
NZ541753A (en) | 2008-12-24 |
PT1592402E (pt) | 2013-06-25 |
CA2512988A1 (en) | 2004-08-12 |
MXPA05007683A (es) | 2005-09-30 |
SI1592402T1 (sl) | 2013-08-30 |
HK1082659A1 (en) | 2006-06-16 |
BRPI0406913B8 (pt) | 2021-05-25 |
JP2007525413A (ja) | 2007-09-06 |
CN1741787A (zh) | 2006-03-01 |
CA2512988C (en) | 2015-11-10 |
AU2004207498A1 (en) | 2004-08-12 |
BRPI0406913A (pt) | 2006-01-03 |
BRPI0406913B1 (pt) | 2016-03-01 |
AR042902A1 (es) | 2005-07-06 |
FR2850275A1 (fr) | 2004-07-30 |
FR2850275B1 (fr) | 2005-04-08 |
WO2004066925B1 (en) | 2004-12-09 |
EP1592402A4 (en) | 2009-01-14 |
CN103169655A (zh) | 2013-06-26 |
DK1592402T3 (da) | 2013-06-24 |
RU2362546C2 (ru) | 2009-07-27 |
JP5371187B2 (ja) | 2013-12-18 |
RU2005126729A (ru) | 2006-03-10 |
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