BRPI0406913B8 - dispersão de cristais de sabor mascarado ou de grânulos de substâncias ativas, cápsulas macias mascáveis preenchidas com a referida dispersão, e processo para a preparação da mesma - Google Patents

dispersão de cristais de sabor mascarado ou de grânulos de substâncias ativas, cápsulas macias mascáveis preenchidas com a referida dispersão, e processo para a preparação da mesma

Info

Publication number
BRPI0406913B8
BRPI0406913B8 BRPI0406913A BRPI0406913A BRPI0406913B8 BR PI0406913 B8 BRPI0406913 B8 BR PI0406913B8 BR PI0406913 A BRPI0406913 A BR PI0406913A BR PI0406913 A BRPI0406913 A BR PI0406913A BR PI0406913 B8 BRPI0406913 B8 BR PI0406913B8
Authority
BR
Brazil
Prior art keywords
dispersion
crystals
active substance
same
preparing
Prior art date
Application number
BRPI0406913A
Other languages
English (en)
Inventor
Rose Fabrice
Meissonnier Julien
Madeleine Bohn Marie
Original Assignee
R P Scherer Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R P Scherer Tech Inc filed Critical R P Scherer Tech Inc
Publication of BRPI0406913A publication Critical patent/BRPI0406913A/pt
Publication of BRPI0406913B1 publication Critical patent/BRPI0406913B1/pt
Publication of BRPI0406913B8 publication Critical patent/BRPI0406913B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

"dispersão de cristais de sabor mascarado ou de grânulos de substâncias ativas, cápsulas macias mascáveis preenchidas com a referida dispersão, e processo para a preparação da mesma". a presente invenção se refere a uma dispersão de cristais ou de grânulos de substância ativa em um veículo lipófilo, os referidos cristais e grânulos sendo revestidos por um revestimento com o objetivo de mascaramento de sabor. a presente invenção também se refere a formas de dosagem unitárias e de forma preferida a cápsulas de gelatina macia mascáveis ou de rápida dissolução, preenchidas com a referida dispersão assim como a processo para a fabricação da mesma.
BRPI0406913A 2003-01-24 2004-01-21 dispersão de cristais de sabor mascarado ou de grânulos de substâncias ativas, cápsulas macias mascáveis preenchidas com a referida dispersão, e processo para a preparação da mesma BRPI0406913B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0300824A FR2850275B1 (fr) 2003-01-24 2003-01-24 Capsules molles a macher contenant une substance active a gout masque
PCT/US2004/001463 WO2004066925A2 (en) 2003-01-24 2004-01-21 Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same

Publications (3)

Publication Number Publication Date
BRPI0406913A BRPI0406913A (pt) 2006-01-03
BRPI0406913B1 BRPI0406913B1 (pt) 2016-03-01
BRPI0406913B8 true BRPI0406913B8 (pt) 2021-05-25

Family

ID=32669215

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0406913A BRPI0406913B8 (pt) 2003-01-24 2004-01-21 dispersão de cristais de sabor mascarado ou de grânulos de substâncias ativas, cápsulas macias mascáveis preenchidas com a referida dispersão, e processo para a preparação da mesma

Country Status (19)

Country Link
EP (1) EP1592402B1 (pt)
JP (1) JP5371187B2 (pt)
CN (2) CN103169655A (pt)
AR (1) AR042902A1 (pt)
AU (1) AU2004207498B2 (pt)
BR (1) BRPI0406913B8 (pt)
CA (1) CA2512988C (pt)
DK (1) DK1592402T3 (pt)
ES (1) ES2415660T3 (pt)
FR (1) FR2850275B1 (pt)
HK (1) HK1082659A1 (pt)
MX (1) MXPA05007683A (pt)
NO (1) NO339528B1 (pt)
NZ (1) NZ541753A (pt)
PT (1) PT1592402E (pt)
RU (1) RU2362546C2 (pt)
SI (1) SI1592402T1 (pt)
UA (1) UA84140C2 (pt)
WO (1) WO2004066925A2 (pt)

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US7169385B2 (en) 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
AU2004277951B2 (en) 2003-09-29 2010-11-11 Soft Gel Technologies, Inc. Solubilized CoQ-10
US20080020022A1 (en) * 2006-06-05 2008-01-24 Udell Ronald G Chewable co-enzyme q-10 capsule
US20070292501A1 (en) * 2006-06-05 2007-12-20 Udell Ronald G Chewable soft gelatin capsules
US8343541B2 (en) 2007-03-15 2013-01-01 Soft Gel Technologies, Inc. Ubiquinol and alpha lipoic acid compositions
BRPI0814115B8 (pt) * 2007-07-19 2021-05-25 R Tech Ueno Ltd composição farmacêutica compreendendo o composto 11-deóxi-prostaglandina e método para estabilizar o composto
FR2935084B1 (fr) * 2008-08-19 2011-05-06 Pancosma Sa Pour L Ind Des Produits Biochimiques Additif pour l'alimentation animale et son procede de preparation
GB201006218D0 (en) 2010-04-14 2010-06-02 Ayanda As Composition
CA2706272C (en) * 2010-06-03 2020-05-05 Accucaps Industries Limited Multi phase soft gel capsules, apparatus and method thereof
CA2706270C (en) * 2010-06-03 2020-01-07 Accucaps Industries Limited Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation
CN103402504B (zh) * 2011-02-11 2015-10-14 西梯茜生命工学股份有限公司 包含西地那非游离碱的膜制剂及其生产方法
EP3178470A1 (en) * 2011-04-11 2017-06-14 Vitux Group AS Oral pharmaceutical dispersion compositions
EP2699267A4 (en) * 2011-04-18 2014-11-12 Lipidor Ab LIQUID CARRIER FOR THE ORAL DELIVERY OF A PHARMACOLOGICAL ACTIVE SUBSTANCE
CN102241782B (zh) * 2011-05-18 2013-01-30 清华大学 一种淀粉乙酸酯的制备方法及其在去除水中硝酸盐的应用
CN102813275B (zh) 2011-06-10 2015-09-30 杭州养生堂保健品有限公司 一种咀嚼型软胶囊皮和咀嚼型软胶囊
DE102012014848A1 (de) * 2012-07-27 2012-10-31 Heilerde-Gesellschaft Luvos Just GmbH & Co. KG Heilerde-Zubereitung
US20150209360A1 (en) * 2014-01-30 2015-07-30 Orbz, Llc Oral caffeine delivery composition
FR3027802B1 (fr) * 2014-10-31 2018-03-02 Ethypharm Granules de principe actif a double masquage de gout, leur procede de preparation et comprimes orodispersibles les contenant
AU2016238337B2 (en) * 2015-03-26 2020-08-13 Patheon Softgels Inc. Liquisoft capsules
HUE059630T2 (hu) 2016-03-15 2022-11-28 Acer Therapeutics Inc Nátrium-fenil-butirátot tartalmazó, kellemes ízû készítmények és alkalmazásaik
JP6942342B2 (ja) * 2016-11-02 2021-09-29 富士カプセル株式会社 ソフトカプセル皮膜
JP2018121699A (ja) * 2017-01-30 2018-08-09 株式会社アクレス クリルオイルを充填したカプセル剤
CN107373744B (zh) * 2017-07-13 2018-11-09 云南中烟工业有限责任公司 一种维生素c微胶囊的制备方法及其在卷烟中的应用
CN108524464A (zh) * 2018-05-17 2018-09-14 安士制药（中山）有限公司 一种西甲硅油软胶囊的制备方法
CA3129404A1 (en) 2019-02-22 2020-08-27 Catalent U.K. Swindon Zydis Limited Preserving functionally-coated api particles produced by solventless mixing processes in aqueous suspension
EP3927314B1 (en) * 2019-02-22 2023-08-23 Catalent U.K. Swindon Zydis Limited Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products
CN113490486A (zh) 2019-02-22 2021-10-08 康特伦英国斯温顿捷迪斯有限公司 最小化团聚、曝气和保持包含布洛芬的药物组合物的包衣
WO2022106923A1 (en) 2020-11-18 2022-05-27 BioPharma Synergies, S. L. Orodispersible powder composition comprising an antihistamine compound

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Also Published As

Publication number Publication date
SI1592402T1 (sl) 2013-08-30
FR2850275B1 (fr) 2005-04-08
EP1592402A2 (en) 2005-11-09
JP2007525413A (ja) 2007-09-06
RU2005126729A (ru) 2006-03-10
ES2415660T3 (es) 2013-07-26
NZ541753A (en) 2008-12-24
WO2004066925A2 (en) 2004-08-12
CN1741787A (zh) 2006-03-01
PT1592402E (pt) 2013-06-25
AU2004207498A1 (en) 2004-08-12
BRPI0406913A (pt) 2006-01-03
UA84140C2 (ru) 2008-09-25
FR2850275A1 (fr) 2004-07-30
CA2512988A1 (en) 2004-08-12
HK1082659A1 (en) 2006-06-16
WO2004066925B1 (en) 2004-12-09
AU2004207498B2 (en) 2008-10-30
CN103169655A (zh) 2013-06-26
NO339528B1 (no) 2016-12-27
BRPI0406913B1 (pt) 2016-03-01
CA2512988C (en) 2015-11-10
EP1592402A4 (en) 2009-01-14
JP5371187B2 (ja) 2013-12-18
DK1592402T3 (da) 2013-06-24
WO2004066925A3 (en) 2004-10-28
EP1592402B1 (en) 2013-03-20
AR042902A1 (es) 2005-07-06
MXPA05007683A (es) 2005-09-30
RU2362546C2 (ru) 2009-07-27
NO20053681L (no) 2005-08-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI.A61K 47/06, A61K 9/00, A61K 9/48, A61K 9/64, A61P 29/00

Ipc: A61K 47/06 (2011.01), A61K 9/00 (2011.01), A61K 9/

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notice of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/03/2016, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/01/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF