UA83483C2 - Способ лечения синдрома "беспокойных ног", который включает применение комплексного соединения железа - Google Patents
Способ лечения синдрома "беспокойных ног", который включает применение комплексного соединения железа Download PDFInfo
- Publication number
- UA83483C2 UA83483C2 UAA200508760A UA2005008760A UA83483C2 UA 83483 C2 UA83483 C2 UA 83483C2 UA A200508760 A UAA200508760 A UA A200508760A UA 2005008760 A UA2005008760 A UA 2005008760A UA 83483 C2 UA83483 C2 UA 83483C2
- Authority
- UA
- Ukraine
- Prior art keywords
- aai
- savzsa
- apa
- aye
- sayezsa
- Prior art date
Links
- 208000005793 Restless legs syndrome Diseases 0.000 title abstract description 4
- 150000004698 iron complex Chemical class 0.000 title abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract description 6
- 229910052742 iron Inorganic materials 0.000 abstract description 3
- 235000013929 Psidium pyriferum Nutrition 0.000 description 5
- 244000236580 Psidium pyriferum Species 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- MYLBTCQBKAKUTJ-UHFFFAOYSA-N 7-methyl-6,8-bis(methylsulfanyl)pyrrolo[1,2-a]pyrazine Chemical compound C1=CN=CC2=C(SC)C(C)=C(SC)N21 MYLBTCQBKAKUTJ-UHFFFAOYSA-N 0.000 description 3
- 206010028813 Nausea Diseases 0.000 description 3
- 208000035475 disorder Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000008693 nausea Effects 0.000 description 3
- 241000223477 Abea Species 0.000 description 2
- 206010003591 Ataxia Diseases 0.000 description 2
- 208000012661 Dyskinesia Diseases 0.000 description 2
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 description 2
- 208000004547 Hallucinations Diseases 0.000 description 2
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 2
- 206010041349 Somnolence Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 241000566146 Asio Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021036 Hyponatraemia Diseases 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010022971 Iron Deficiencies Diseases 0.000 description 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 1
- 241000408551 Meza Species 0.000 description 1
- 241000840267 Moma Species 0.000 description 1
- 241000871434 Pegia Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 235000000935 Santalum yasi Nutrition 0.000 description 1
- 241000775525 Santalum yasi Species 0.000 description 1
- 241001128391 Taia Species 0.000 description 1
- 241000724822 Teia Species 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 208000027697 autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency Diseases 0.000 description 1
- 229940058679 baza Drugs 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- FFGPTBGBLSHEPO-UHFFFAOYSA-N carbamazepine Chemical compound C1=CC2=CC=CC=C2N(C(=O)N)C2=CC=CC=C21 FFGPTBGBLSHEPO-UHFFFAOYSA-N 0.000 description 1
- 229960000623 carbamazepine Drugs 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 206010016256 fatigue Diseases 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 229960002870 gabapentin Drugs 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- MVZXTUSAYBWAAM-UHFFFAOYSA-N iron;sulfuric acid Chemical compound [Fe].OS(O)(=O)=O MVZXTUSAYBWAAM-UHFFFAOYSA-N 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 229960004502 levodopa Drugs 0.000 description 1
- YEHCICAEULNIGD-MZMPZRCHSA-N pergolide Chemical compound C1=CC([C@H]2C[C@@H](CSC)CN([C@@H]2C2)CCC)=C3C2=CNC3=C1 YEHCICAEULNIGD-MZMPZRCHSA-N 0.000 description 1
- 229960004851 pergolide Drugs 0.000 description 1
- QGFSVPWZEPKNDV-BRTFOEFASA-N ranp Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)[C@@H](C)CC)C1=CC=CC=C1 QGFSVPWZEPKNDV-BRTFOEFASA-N 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 208000012201 sexual and gender identity disease Diseases 0.000 description 1
- 208000015891 sexual disease Diseases 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Изобретение относится к способу лечения синдрома беспокойных ног, который включает применение комплексного соединения железа. Скорость высвобождения железа из этого соединения превышает таковую для IDI (декстрин железа для инъекций) и определяется при концентрации, по меньшей мере, 2,000 мкг/дл.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/389,228 US6960571B2 (en) | 2003-03-14 | 2003-03-14 | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
| PCT/US2003/015087 WO2004082693A1 (en) | 2003-03-14 | 2003-05-13 | Composition for administration of iron for the treatment of restless legs syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA83483C2 true UA83483C2 (ru) | 2008-07-25 |
Family
ID=32962229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200508760A UA83483C2 (ru) | 2003-03-14 | 2003-05-13 | Способ лечения синдрома "беспокойных ног", который включает применение комплексного соединения железа |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6960571B2 (ru) |
| EP (1) | EP1603580B1 (ru) |
| JP (2) | JP2006520322A (ru) |
| KR (1) | KR100978377B1 (ru) |
| CN (1) | CN1771044B (ru) |
| AT (1) | ATE400280T1 (ru) |
| AU (1) | AU2003249635C1 (ru) |
| BR (1) | BR0318185A (ru) |
| CA (1) | CA2518971C (ru) |
| CY (1) | CY1110407T1 (ru) |
| DE (1) | DE60322121D1 (ru) |
| DK (1) | DK1603580T3 (ru) |
| ES (1) | ES2309403T3 (ru) |
| HK (1) | HK1089666A1 (ru) |
| HR (1) | HRP20050796A2 (ru) |
| IL (1) | IL170386A (ru) |
| MX (1) | MXPA05009786A (ru) |
| NO (1) | NO20054728L (ru) |
| PL (1) | PL206810B1 (ru) |
| PT (1) | PT1603580E (ru) |
| RS (1) | RS51823B (ru) |
| RU (1) | RU2319490C2 (ru) |
| SI (1) | SI1603580T1 (ru) |
| UA (1) | UA83483C2 (ru) |
| WO (1) | WO2004082693A1 (ru) |
| ZA (1) | ZA200508308B (ru) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US20060116349A1 (en) * | 2003-03-14 | 2006-06-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
| EP1655040A1 (en) * | 2004-10-08 | 2006-05-10 | Bracco Imaging, S.P.A. | Contrast agent formulations for the visualization of the lymphatic system |
| EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
| KR20080078075A (ko) * | 2005-12-20 | 2008-08-26 | 세레우사이언스 아베 | 하지 불안 증후군의 치료 및 진단을 위한 방법 및 조성물 |
| CA2634751C (en) * | 2005-12-23 | 2017-10-31 | Ajay Gupta | Parenteral nutrition composition containing iron |
| AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
| AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
| KR20140117678A (ko) * | 2006-01-06 | 2014-10-07 | 루이트폴드 파머수티컬스, 인코퍼레이티드 | 철을 투여하기 위한 방법 및 조성물 |
| US20080132465A1 (en) * | 2006-12-05 | 2008-06-05 | Vincent Windisch | Apparatus and method for isolating iron components from serum |
| EP1941869A1 (en) * | 2007-01-04 | 2008-07-09 | Vifor (International) Ag | Multicompartment bag for storage of iron preparations |
| MX2010010390A (es) * | 2008-03-28 | 2011-02-22 | Chyna Llc | Uso de ferritina para tratar desordenes de deficiencia de hierro. |
| WO2009143439A1 (en) * | 2008-05-23 | 2009-11-26 | Hospira, Inc. | Packaged iron sucrose products |
| JP2012508186A (ja) * | 2008-11-06 | 2012-04-05 | バイオティ セラピーズ，インク． | むずむず脚症候群および睡眠障害の治療 |
| EP3156075B1 (en) | 2009-03-25 | 2020-10-14 | Pharmacosmos Holding A/S | An oligosaccharide and a process for preparation thereof |
| US8058076B2 (en) * | 2009-03-31 | 2011-11-15 | Astron Research Limited | In-vitro method for testing bioequivalence of iron-sucrose formulation |
| CN102440999A (zh) * | 2010-10-15 | 2012-05-09 | 天津瑞普生物技术股份有限公司 | 一种用于防治仔猪缺铁性贫血、低过敏反应的复方药物 |
| WO2012104204A1 (en) | 2011-01-31 | 2012-08-09 | Vifor (International) Ag | Iron-carbohydrate complex compounds for the intravenous therapy of malaria |
| DK2968503T3 (en) | 2013-03-15 | 2018-12-03 | Intrinsic Lifesciences Llc | ANTI-HEPCIDIN ANTIBODIES AND APPLICATIONS THEREOF |
| JP2014132029A (ja) * | 2014-04-03 | 2014-07-17 | Chyna Llc | 鉄欠乏性障害を治療するためのフェリチンの使用 |
| US10323088B2 (en) | 2014-09-22 | 2019-06-18 | Intrinsic Lifesciences Llc | Humanized anti-hepcidin antibodies and uses thereof |
| US20170304367A1 (en) * | 2014-10-29 | 2017-10-26 | University Of Utah Research Foundation | Methods of treating hypoxia-associated optical conditions with cartilage oligo matrix protein-angiopoietin 1 (comp-ang1) |
| EP2913054A1 (en) | 2015-03-19 | 2015-09-02 | Pharmacosmos Holding A/s | Iron carbohydrate complex for treatment of restless leg syndrome (rls) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5248492A (en) | 1986-07-03 | 1993-09-28 | Advanced Magnetics, Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| US4827945A (en) | 1986-07-03 | 1989-05-09 | Advanced Magnetics, Incorporated | Biologically degradable superparamagnetic materials for use in clinical applications |
| US5700832A (en) * | 1994-10-19 | 1997-12-23 | Daewon Pharm. Co., Ltd. | Antianemic agent containing iron and difructose |
| SE9803760D0 (sv) | 1998-11-04 | 1998-11-04 | Jan Hedner | Sätt att behandla och diagnostisera syndromet restless legs och motsvarande medel |
| US6611707B1 (en) * | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
| AU2001251306A1 (en) | 2000-04-04 | 2001-10-15 | Siegel, Jerome M. | Treatment of sleep disorders with hypocretin-1 |
-
2003
- 2003-03-14 US US10/389,228 patent/US6960571B2/en not_active Expired - Lifetime
- 2003-05-13 WO PCT/US2003/015087 patent/WO2004082693A1/en active Application Filing
- 2003-05-13 SI SI200331383T patent/SI1603580T1/sl unknown
- 2003-05-13 RU RU2005131832/14A patent/RU2319490C2/ru not_active IP Right Cessation
- 2003-05-13 CN CN038260972A patent/CN1771044B/zh not_active Expired - Fee Related
- 2003-05-13 EP EP03816391A patent/EP1603580B1/en not_active Expired - Lifetime
- 2003-05-13 PT PT03816391T patent/PT1603580E/pt unknown
- 2003-05-13 AT AT03816391T patent/ATE400280T1/de active
- 2003-05-13 DE DE60322121T patent/DE60322121D1/de not_active Expired - Lifetime
- 2003-05-13 PL PL378875A patent/PL206810B1/pl not_active IP Right Cessation
- 2003-05-13 ES ES03816391T patent/ES2309403T3/es not_active Expired - Lifetime
- 2003-05-13 BR BRPI0318185-5A patent/BR0318185A/pt not_active Application Discontinuation
- 2003-05-13 UA UAA200508760A patent/UA83483C2/ru unknown
- 2003-05-13 KR KR1020057017249A patent/KR100978377B1/ko not_active IP Right Cessation
- 2003-05-13 CA CA002518971A patent/CA2518971C/en not_active Expired - Lifetime
- 2003-05-13 RS YU20050695A patent/RS51823B/sr unknown
- 2003-05-13 MX MXPA05009786A patent/MXPA05009786A/es active IP Right Grant
- 2003-05-13 DK DK03816391T patent/DK1603580T3/da active
- 2003-05-13 JP JP2004569663A patent/JP2006520322A/ja active Pending
- 2003-05-13 AU AU2003249635A patent/AU2003249635C1/en not_active Ceased
-
2005
- 2005-08-18 IL IL170386A patent/IL170386A/en not_active IP Right Cessation
- 2005-09-12 HR HR20050796A patent/HRP20050796A2/hr not_active Application Discontinuation
- 2005-10-13 ZA ZA200508308A patent/ZA200508308B/en unknown
- 2005-10-13 NO NO20054728A patent/NO20054728L/no not_active Application Discontinuation
-
2006
- 2006-09-11 HK HK06110065.3A patent/HK1089666A1/xx not_active IP Right Cessation
-
2008
- 2008-10-08 CY CY20081101119T patent/CY1110407T1/el unknown
-
2010
- 2010-05-26 JP JP2010120637A patent/JP2010180252A/ja active Pending
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