UA80018C2 - Alpha-2-delta-proteins related aminoacids - Google Patents

Alpha-2-delta-proteins related aminoacids Download PDF

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Publication number
UA80018C2
UA80018C2 UAA200507455A UA2005007455A UA80018C2 UA 80018 C2 UA80018 C2 UA 80018C2 UA A200507455 A UAA200507455 A UA A200507455A UA 2005007455 A UA2005007455 A UA 2005007455A UA 80018 C2 UA80018 C2 UA 80018C2
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UA
Ukraine
Prior art keywords
acid
aminomethyl
methylheptanoic
amino
methyloctanoic
Prior art date
Application number
UAA200507455A
Other languages
English (en)
Ukrainian (uk)
Inventor
Nancy Sue Barta
Jacob Bradley Schwarz
Andrew John Thorpe
David Juergen Wustrow
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28675482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA80018(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of UA80018C2 publication Critical patent/UA80018C2/uk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
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    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07—ORGANIC CHEMISTRY
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    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
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    • C07—ORGANIC CHEMISTRY
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    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
UAA200507455A 2002-03-28 2003-03-17 Alpha-2-delta-proteins related aminoacids UA80018C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36841302P 2002-03-28 2002-03-28

Publications (1)

Publication Number Publication Date
UA80018C2 true UA80018C2 (en) 2007-08-10

Family

ID=28675482

Family Applications (2)

Application Number Title Priority Date Filing Date
UA20040907854A UA80116C2 (en) 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein
UAA200507455A UA80018C2 (en) 2002-03-28 2003-03-17 Alpha-2-delta-proteins related aminoacids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UA20040907854A UA80116C2 (en) 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein

Country Status (43)

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US (3) US7064147B2 (sr)
EP (2) EP1492761B1 (sr)
JP (2) JP3831379B2 (sr)
KR (2) KR100694719B1 (sr)
CN (2) CN100462351C (sr)
AP (1) AP1791A (sr)
AR (2) AR039154A1 (sr)
AU (1) AU2003208538B2 (sr)
BR (1) BR0308814A (sr)
CA (1) CA2480872C (sr)
CR (1) CR7501A (sr)
CU (1) CU23331B7 (sr)
CY (1) CY1109304T1 (sr)
DE (1) DE60328469D1 (sr)
DK (1) DK1492761T3 (sr)
EA (2) EA008709B1 (sr)
EC (1) ECSP045319A (sr)
ES (1) ES2327910T3 (sr)
GE (2) GEP20084298B (sr)
GT (2) GT200300072A (sr)
HK (1) HK1076627A1 (sr)
HR (2) HRP20040891A2 (sr)
IL (2) IL164110A0 (sr)
IS (2) IS7451A (sr)
MA (1) MA27188A1 (sr)
MX (1) MXPA04009373A (sr)
MY (1) MY131424A (sr)
NI (1) NI200300043A (sr)
NO (2) NO20044614L (sr)
NZ (2) NZ541320A (sr)
OA (1) OA12795A (sr)
PA (1) PA8570001A1 (sr)
PE (1) PE20040349A1 (sr)
PL (1) PL209750B1 (sr)
PT (1) PT1492761E (sr)
RS (2) RS83604A (sr)
SI (1) SI1492761T1 (sr)
TN (1) TNSN04186A1 (sr)
TW (1) TWI225864B (sr)
UA (2) UA80116C2 (sr)
UY (1) UY27738A1 (sr)
WO (1) WO2003082807A2 (sr)
ZA (1) ZA200407536B (sr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129693A1 (de) * 2001-06-22 2003-01-02 Jan Loock Verfahren zur extrakorporalen qualitativen und/oder quantitativen Erfassung neurotoxischer Substanzen im Blutplasma eines Individuums
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US7419981B2 (en) 2002-08-15 2008-09-02 Pfizer Inc. Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
WO2005002585A1 (en) * 2003-07-02 2005-01-13 Warner-Lambert Company Llc Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
KR100774625B1 (ko) * 2003-09-25 2007-11-08 워너-램버트 캄파니 엘엘씨 치료제 베타 아미노산
BRPI0414781A (pt) * 2003-09-25 2006-11-21 Warner Lambert Co aminoácidos com afinidade para a proteìna (alfa)2(delta)
KR100847922B1 (ko) * 2004-03-12 2008-07-22 워너-램버트 캄파니 엘엘씨 Ｃ1-대칭 비스포스핀 리간드 및 프레가발린의 비대칭합성에서의 이들의 용도
RU2007100355A (ru) * 2004-07-09 2008-07-20 Уорнер-Ламберт Компани Ллс (Us) Получение бета-аминокислот, обладающих аффинностью к альфа-2-дельта-белку
WO2006092692A1 (en) * 2005-03-01 2006-09-08 Pfizer Limited Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
EP1863780A1 (en) * 2005-03-24 2007-12-12 Pharmacia & Upjohn Company LLC Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein
WO2007052134A1 (en) * 2005-11-04 2007-05-10 Pfizer Limited (2s)-2-aminomethyl-5-ethyl heptanoic acid its pharmaceutical use
WO2007057756A2 (en) * 2005-11-17 2007-05-24 Pfizer Limited Isocystene derivatives for the treatment of pain
MX2008011396A (es) * 2006-03-06 2008-09-18 Pfizer Prod Inc Ligandos alfa-2-delta para sueño no reconstituyente.
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
US20110124705A1 (en) * 2009-11-24 2011-05-26 Xenoport, Inc. Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof
US8962831B2 (en) 2011-05-17 2015-02-24 Principia Biopharma Inc. Tyrosine kinase inhibitors
WO2012158795A1 (en) 2011-05-17 2012-11-22 Principia Biopharma Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
MX355728B (es) 2011-05-17 2018-04-27 Univ California Inhibidores de cinasas.
CN103164756A (zh) * 2011-12-12 2013-06-19 苏州艾隆科技有限公司 贵重药品的管理方法及其系统
CN104822681B (zh) 2012-09-10 2018-01-30 普林斯匹亚生物制药公司 作为激酶抑制剂的吡唑并嘧啶化合物
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
ES2841248T3 (es) 2014-02-21 2021-07-07 Principia Biopharma Inc Sales y forma sólida de un inhibidor de BTK
WO2016100914A1 (en) 2014-12-18 2016-06-23 Gourlay Steven Treatment of pemphigus
EP3313839A1 (en) 2015-06-24 2018-05-02 Principia Biopharma Inc. Tyrosine kinase inhibitors
EP3478273A1 (en) 2016-06-29 2019-05-08 Principia Biopharma Inc. Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1377736A (fr) * 1962-12-21 1964-11-06 Hoffmann La Roche Procédé pour la préparation d'acides amino-carboxyliques
FR1377366A (fr) 1963-08-19 1964-11-06 Dispositif de protection de sécurité pour appareils électriques
KR880007441A (ko) * 1986-12-11 1988-08-27 알렌 제이.스피겔 스피로-치환된 글루타르아미드 이뇨제
US5407960A (en) 1989-12-22 1995-04-18 Schering Corporation Mercaptocycloacyl aminoacid endopeptidase inhibitors
US5614498A (en) 1990-06-07 1997-03-25 Banyu Pharmaceutical Co., Ltd. Endothelin antagonistic substance
US5011066A (en) * 1990-07-27 1991-04-30 Motorola, Inc. Enhanced collapse solder interconnection
US5239113A (en) 1991-10-15 1993-08-24 Monsanto Company Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof
EP0561758A3 (en) 1992-03-18 1995-04-05 Monsanto Co Method of preparing optically active homo-beta-amino acids
US5578606A (en) * 1992-10-30 1996-11-26 G. D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors
AU684878B2 (en) 1993-11-24 1998-01-08 Merck & Co., Inc. Compounds and the use thereof to promote the release of growth hormone(s)
WO1995015684A1 (en) 1993-12-12 1995-06-15 Agrogene, Ltd. A novel method to protect plants from fungal infection
US5472830A (en) 1994-04-18 1995-12-05 Ocg Microelectronic Materials, Inc. Non-corrosion photoresist stripping composition
AU3586097A (en) 1996-07-12 1998-02-09 G.D. Searle & Co. Asymetric synthesis of chiral beta-amino acids
AU733896B2 (en) * 1996-10-23 2001-05-31 Warner-Lambert Company Substituted gamma aminobutyric acids as pharmaceutical agents
US6306909B1 (en) 1997-03-12 2001-10-23 Queen's University At Kingston Anti-epileptogenic agents
GB2323594A (en) 1997-03-25 1998-09-30 Victor Martin 2-amino-alkanoic acid derivatives, 2-amino alcohols and diamines
US6201023B1 (en) 1997-06-10 2001-03-13 Agrogene Ltd. Methods and compositions to protect crops against plant parasitic nematodes
US6011066A (en) 1998-02-02 2000-01-04 Veterans General Hospital-Taipei Method for treating septic shock
JP2002506829A (ja) 1998-03-16 2002-03-05 サイトビア インコーポレイテッド ジペプチドのアポトーシスインヒビターおよびそれらの使用
EP1013769A1 (en) 1998-12-22 2000-06-28 Dsm N.V. Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity
FR2791982B1 (fr) 1999-04-06 2002-12-27 Inst Nat Sante Rech Med Inhibiteurs de lta4 hydrolase et leurs applications therapeutiques.
DK1192125T3 (da) * 1999-06-10 2009-02-16 Warner Lambert Co Mono-substituerede 3-propyl-gamma-aminosmörsyrer
CA2408246A1 (en) * 2000-05-16 2001-11-22 Warner-Lambert Company Cell line for the expression of an .alpha.2.delta.2 calcium channel subunit
EP1282594A1 (en) 2000-05-17 2003-02-12 Medivir UK Ltd Branched amino acids
EP1317426B1 (de) 2000-09-14 2005-11-16 Grünenthal GmbH Beta-thio-aminosäuren
DE10048715A1 (de) 2000-09-30 2004-05-19 Grünenthal GmbH Verwendung von Aminosäure zur Behandlung von Schmerz
CA2440834A1 (en) * 2001-03-13 2002-09-19 Queen's University At Kingston Anti-epileptogenic agents
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
GB0219024D0 (en) * 2002-08-15 2002-09-25 Pfizer Ltd Synergistic combinations
CN1228312C (zh) * 2002-12-27 2005-11-23 中国科学院化学研究所 以酮为原料合成β—氨基酸的方法

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