UA79578C2 - Controlled release composition containing galantamine, process for the preparation thereof, dosage form and packaging - Google Patents
Controlled release composition containing galantamine, process for the preparation thereof, dosage form and packaging Download PDFInfo
- Publication number
- UA79578C2 UA79578C2 UA2001064400A UA2001064400A UA79578C2 UA 79578 C2 UA79578 C2 UA 79578C2 UA 2001064400 A UA2001064400 A UA 2001064400A UA 2001064400 A UA2001064400 A UA 2001064400A UA 79578 C2 UA79578 C2 UA 79578C2
- Authority
- UA
- Ukraine
- Prior art keywords
- coating
- galantamine
- release
- spheres
- particles
- Prior art date
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- ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 title abstract description 92
- ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 title abstract description 47
- 229960003980 galantamine Drugs 0.000 title abstract description 46
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Classifications
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
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- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98204447 | 1998-12-24 | ||
| PCT/EP1999/010257 WO2000038686A1 (fr) | 1998-12-24 | 1999-12-20 | Composition de galantamine a liberation controlee |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA79578C2 true UA79578C2 (en) | 2007-07-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2001064400A UA79578C2 (en) | 1998-12-24 | 1999-12-20 | Controlled release composition containing galantamine, process for the preparation thereof, dosage form and packaging |
Country Status (36)
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|---|---|
| US (3) | US7160559B1 (fr) |
| EP (1) | EP1140105B1 (fr) |
| JP (1) | JP2002533396A (fr) |
| KR (1) | KR100437105B1 (fr) |
| CN (1) | CN100370990C (fr) |
| AP (1) | AP1414A (fr) |
| AR (2) | AR022008A1 (fr) |
| AT (1) | ATE252386T1 (fr) |
| AU (1) | AU775914B2 (fr) |
| BG (1) | BG65306B1 (fr) |
| BR (1) | BR9916835A (fr) |
| CA (1) | CA2358062C (fr) |
| CZ (1) | CZ301658B6 (fr) |
| DE (1) | DE69912311T2 (fr) |
| DK (1) | DK1140105T3 (fr) |
| EA (1) | EA004936B1 (fr) |
| EE (1) | EE04996B1 (fr) |
| ES (1) | ES2211215T3 (fr) |
| HK (1) | HK1043062A1 (fr) |
| HR (1) | HRP20010463B1 (fr) |
| HU (1) | HUP0104778A3 (fr) |
| ID (1) | ID29021A (fr) |
| IL (2) | IL143899A0 (fr) |
| MY (1) | MY122411A (fr) |
| NO (1) | NO327988B1 (fr) |
| NZ (1) | NZ511643A (fr) |
| OA (1) | OA11740A (fr) |
| PL (1) | PL349501A1 (fr) |
| PT (1) | PT1140105E (fr) |
| SI (1) | SI1140105T1 (fr) |
| SK (1) | SK287676B6 (fr) |
| TR (1) | TR200101822T2 (fr) |
| TW (1) | TWI262079B (fr) |
| UA (1) | UA79578C2 (fr) |
| WO (1) | WO2000038686A1 (fr) |
| ZA (1) | ZA200105132B (fr) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000030446A1 (fr) | 1998-11-23 | 2000-06-02 | Bonnie Davis | Formulations de dosage d'inhibiteurs de l'acetylcholinesterase |
| SI1140105T1 (en) * | 1998-12-24 | 2004-04-30 | Janssen Pharmaceutica N.V. | Controlled release galantamine composition |
| CA2310926C (fr) * | 2000-04-03 | 2002-10-15 | Janssen Pharmaceutica N.V. | Utilisation de la galantamine pour le traitement du comportement neuropsychiatrique associe a la maladie d'alzheimer |
| CA2310950C (fr) * | 2000-04-03 | 2005-11-08 | Janssen Pharmaceutica N.V. | Posologie de galantamine efficace qui reduit les effets secondaires |
| DE10134038A1 (de) * | 2001-07-12 | 2003-02-06 | Hf Arzneimittelforsch Gmbh | Wirkstoff-Kombination zur medikamentösen Therapie der Nikotinabhängigkeit |
| WO2003032914A2 (fr) * | 2001-10-17 | 2003-04-24 | Eisai Co., Ltd. | Procedes de traitement de la consommation abusive de substances psychoactives a l'aide d'inhibiteurs de la cholinesterase |
| FR2842735B1 (fr) | 2002-07-26 | 2006-01-06 | Flamel Tech Sa | Microcapsules a liberation modifiee de principes actifs peu solubles pour l'administration per os |
| DE10235556A1 (de) * | 2002-08-03 | 2004-02-19 | Hf Arzneimittelforschung Gmbh | Medikament und Verfahren zur Verringerung des Alkohol- und/oder Tabakkonsums |
| WO2004056363A2 (fr) | 2002-12-20 | 2004-07-08 | Niconovum Ab | Materiau particulaire contenant de la nicotine chimiquement et physiquement stable |
| ITMI20030827A1 (it) * | 2003-04-18 | 2004-10-19 | Unihart Corp | Composizione farmaceutica contenente l'associazione levodopa/carbidopa. |
| US7250258B2 (en) | 2003-12-15 | 2007-07-31 | Pgxhealth Llc | CDK5 genetic markers associated with galantamine response |
| WO2005065662A1 (fr) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Formulations solides d'administration de galantamine |
| CA2551946A1 (fr) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Formulations de galantamine |
| EP2340813A1 (fr) * | 2003-12-31 | 2011-07-06 | Actavis Group PTC ehf. | Formes galeniques solides a base de galantamine |
| GB0408308D0 (en) * | 2004-04-14 | 2004-05-19 | Vectura Ltd | Pharmaceutical compositions |
| US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
| US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
| JP2008525313A (ja) * | 2004-12-27 | 2008-07-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗痴呆薬の安定化方法 |
| US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
| KR101213345B1 (ko) * | 2005-04-28 | 2012-12-17 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 항치매약을 함유하는 조성물 |
| US20090087488A1 (en) * | 2005-09-05 | 2009-04-02 | Rajan Kumar Verma | Galantamine-containing controlled release oral dosage forms, processes for the preparation thereof and use of the manufacture of a medicament |
| US20070092568A1 (en) * | 2005-10-10 | 2007-04-26 | Gore Subhash P | Galantamine compositions |
| EP1998748B1 (fr) | 2006-03-16 | 2015-01-14 | NicoNovum AB | Composition améliorée de tabac à priser |
| HUE029173T2 (hu) * | 2006-04-26 | 2017-02-28 | Alphapharm Pty Ltd | Szabályozott hatóanyag-leadású készítmények, amelyek tartalmaznak nem bevont diszkrét egység(ek)et és egy késleltetett hatóanyag-leadású mátrixot |
| WO2008062426A2 (fr) * | 2006-08-02 | 2008-05-29 | Emcure Pharmaceuticals Limited | Formulation de dérivés de benzazépine |
| WO2008048469A2 (fr) * | 2006-10-13 | 2008-04-24 | Actavis Group Pct Hf | Formulations de galantamine à libération contrôlée |
| DE102006056697A1 (de) * | 2006-11-30 | 2008-06-05 | Ratiopharm Gmbh | Galanthamin-haltiges Arzneimittel mit kontrollierter Freisetzung |
| AU2008213744B2 (en) * | 2007-02-09 | 2013-12-05 | Alphapharm Pty Ltd | A dosage form containing two or more active pharmaceutical ingredients in different physical forms |
| KR100782310B1 (ko) | 2007-03-22 | 2007-12-06 | 현대약품 주식회사 | 갈란타민 또는 이의 약학적으로 허용 가능한 염을 포함하는약학 조성물 |
| US20090035370A1 (en) * | 2007-08-02 | 2009-02-05 | Drugtech Corporation | Dosage form and method of use |
| WO2009024858A1 (fr) * | 2007-08-22 | 2009-02-26 | Aurobindo Pharma Limited | Forme posologique à libération contrôlée de galantamine |
| EP2044933A1 (fr) * | 2007-10-05 | 2009-04-08 | KRKA, D.D., Novo Mesto | Système de matrice à multi-particules contenant de la galantamine |
| WO2009043914A1 (fr) * | 2007-10-05 | 2009-04-09 | Krka, D.D., Novo Mesto | Système matriciel multiparticulaire contenant de la galantamine |
| CA2615137A1 (fr) * | 2007-12-17 | 2009-06-17 | Pharmascience Inc. | Dispositif therapeutique monocouche a liberation controlee |
| EP2116232B1 (fr) * | 2008-05-09 | 2012-02-15 | Ratiopharm GmbH | Médicament à libération contrôlée comprenant de la galanthamine |
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| EP2503996A2 (fr) | 2009-11-26 | 2012-10-03 | USV Limited | Compositions pharmaceutiques à libération contrôlée de galantamine |
| WO2011151359A1 (fr) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Traitement combiné comprenant un inhibiteur de la cholinestérase et un dérivé de thiadiazolidinedione |
| GR1007767B (el) | 2011-07-26 | 2012-11-19 | Φαρματεν Αβεε, | Φαρμακευτικο σκευασμα παρατεταμενης αποδεσμευσης περιεχον γκαλανταμινη και μεθοδος για την παρασκευη αυτου |
| CN109846862A (zh) | 2012-10-25 | 2019-06-07 | 通用医疗公司 | 治疗阿尔茨海默病及相关疾病的组合疗法 |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| WO2015022418A1 (fr) | 2013-08-16 | 2015-02-19 | Takeda Gmbh | Traitement d'une déficience cognitive à l'aide d'un inhibiteur de pde4 |
| US10188757B2 (en) | 2013-10-22 | 2019-01-29 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| US9849125B1 (en) | 2015-11-03 | 2017-12-26 | Banner Lifie Sciences LLC | Anti-overingestion dosage forms |
| US20190240194A1 (en) | 2016-08-31 | 2019-08-08 | The General Hospital Corporation | Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases |
| GB201620095D0 (en) | 2016-11-28 | 2017-01-11 | Terali Innov Sas And Univ De Strasbourg And Inserm (Inst Nat De La Sante Et De La Rech Medicale) And | Novel use |
| CN110769816B (zh) * | 2017-05-19 | 2022-12-06 | 比斯坎神经治疗公司 | 石杉碱的改良释放药物组合物以及其使用方法 |
| US10335375B2 (en) | 2017-05-30 | 2019-07-02 | Patheon Softgels, Inc. | Anti-overingestion abuse deterrent compositions |
| MX2020000577A (es) | 2017-07-20 | 2020-09-10 | Aztherapies Inc | Formulaciones en polvo de cromolina sodica e ibuprofeno. |
| US10213394B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
| US20190247331A1 (en) | 2018-02-15 | 2019-08-15 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
| US10213393B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság | Composition and method for treating neurological disease |
| WO2020010049A1 (fr) | 2018-07-02 | 2020-01-09 | The General Hospital Corporation | FORMULATIONS EN POUDRE DE CROMOGLYCATE DE SODIUM ET D'α-LACTOSE |
| BG67408B1 (bg) | 2019-04-12 | 2022-01-17 | Софарма Ад | Перорален лекарствен състав с растителен алкалоид, за лечение на зависимости |
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| SE450087B (sv) * | 1985-10-11 | 1987-06-09 | Haessle Ab | Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial |
| US4663318A (en) * | 1986-01-15 | 1987-05-05 | Bonnie Davis | Method of treating Alzheimer's disease |
| KR100195399B1 (ko) | 1987-05-04 | 1999-06-15 | 보니데이비스 | 알쯔하이머 병 치료용 의약 |
| CA1326632C (fr) * | 1988-10-26 | 1994-02-01 | Bonnie Davis | Compositions pharmaceutiques a action prolongee contenant de la galanthamine pour le traitement de la maladie d'alzheimer |
| US5085865A (en) * | 1989-04-12 | 1992-02-04 | Warner-Lambert Company | Sustained release pharmaceutical preparations containing an analgesic and a decongestant |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5519017A (en) | 1990-03-29 | 1996-05-21 | Lts Lohmann Therapie-Systeme Gmbh + Co. Kg | Pharmaceutic formulation for the treatment of alcoholism |
| DE4010079A1 (de) * | 1990-03-29 | 1991-10-02 | Lohmann Therapie Syst Lts | Pharmazeutische formulierung zur behandlung des alkoholismus |
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-
1999
- 1999-12-20 SI SI9930484T patent/SI1140105T1/xx unknown
- 1999-12-20 AP APAP/P/2001/002219A patent/AP1414A/en active
- 1999-12-20 EA EA200100713A patent/EA004936B1/ru not_active IP Right Cessation
- 1999-12-20 BR BR9916835-9A patent/BR9916835A/pt not_active Application Discontinuation
- 1999-12-20 JP JP2000590639A patent/JP2002533396A/ja active Pending
- 1999-12-20 PL PL99349501A patent/PL349501A1/xx not_active Application Discontinuation
- 1999-12-20 ES ES99965527T patent/ES2211215T3/es not_active Expired - Lifetime
- 1999-12-20 DK DK99965527T patent/DK1140105T3/da active
- 1999-12-20 EP EP99965527A patent/EP1140105B1/fr not_active Expired - Lifetime
- 1999-12-20 IL IL14389999A patent/IL143899A0/xx active IP Right Grant
- 1999-12-20 CA CA002358062A patent/CA2358062C/fr not_active Expired - Lifetime
- 1999-12-20 WO PCT/EP1999/010257 patent/WO2000038686A1/fr active IP Right Grant
- 1999-12-20 CZ CZ20012182A patent/CZ301658B6/cs not_active IP Right Cessation
- 1999-12-20 SK SK886-2001A patent/SK287676B6/sk not_active IP Right Cessation
- 1999-12-20 HU HU0104778A patent/HUP0104778A3/hu unknown
- 1999-12-20 EE EEP200100319A patent/EE04996B1/xx unknown
- 1999-12-20 AU AU21006/00A patent/AU775914B2/en not_active Expired
- 1999-12-20 OA OA1200100170A patent/OA11740A/en unknown
- 1999-12-20 NZ NZ511643A patent/NZ511643A/en not_active IP Right Cessation
- 1999-12-20 DE DE69912311T patent/DE69912311T2/de not_active Expired - Lifetime
- 1999-12-20 CN CNB998149888A patent/CN100370990C/zh not_active Expired - Lifetime
- 1999-12-20 TR TR2001/01822T patent/TR200101822T2/xx unknown
- 1999-12-20 AT AT99965527T patent/ATE252386T1/de active
- 1999-12-20 ID IDW00200101372A patent/ID29021A/id unknown
- 1999-12-20 KR KR10-2001-7006141A patent/KR100437105B1/ko active IP Right Grant
- 1999-12-20 UA UA2001064400A patent/UA79578C2/uk unknown
- 1999-12-20 US US09/868,991 patent/US7160559B1/en not_active Expired - Lifetime
- 1999-12-20 PT PT99965527T patent/PT1140105E/pt unknown
- 1999-12-23 MY MYPI99005716A patent/MY122411A/en unknown
- 1999-12-23 AR ARP990106725A patent/AR022008A1/es not_active Application Discontinuation
- 1999-12-23 TW TW088122698A patent/TWI262079B/zh not_active IP Right Cessation
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2001
- 2001-06-05 BG BG105564A patent/BG65306B1/bg unknown
- 2001-06-08 NO NO20012857A patent/NO327988B1/no not_active IP Right Cessation
- 2001-06-19 HR HR20010463A patent/HRP20010463B1/xx not_active IP Right Cessation
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