UA65542C2 - Спосіб пригнічення надлишкового продукування фактора некрозу пухлин альфа , спосіб полегшення шкідливих ефектів надлишкового продукування фактора некрозу пухлин альфа та спосіб лікування запального стану або захворювання, пов'язаного з фактором некрозу пухлин. - Google Patents
Спосіб пригнічення надлишкового продукування фактора некрозу пухлин альфа , спосіб полегшення шкідливих ефектів надлишкового продукування фактора некрозу пухлин альфа та спосіб лікування запального стану або захворювання, пов'язаного з фактором некрозу пухлин. Download PDFInfo
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- UA65542C2 UA65542C2 UA99010342A UA99010342A UA65542C2 UA 65542 C2 UA65542 C2 UA 65542C2 UA 99010342 A UA99010342 A UA 99010342A UA 99010342 A UA99010342 A UA 99010342A UA 65542 C2 UA65542 C2 UA 65542C2
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- Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
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- Engineering & Computer Science (AREA)
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- Psychiatry (AREA)
- Pain & Pain Management (AREA)
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- Psychology (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2040696P | 1996-06-25 | 1996-06-25 | |
| PCT/US1997/010898 WO1997049406A1 (en) | 1996-06-25 | 1997-06-24 | Use of k-252a derivative for the treatment of peripheral or central nerve disorders, and cytokine overproduction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA65542C2 true UA65542C2 (uk) | 2004-04-15 |
Family
ID=21798468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA99010342A UA65542C2 (uk) | 1996-06-25 | 1997-06-24 | Спосіб пригнічення надлишкового продукування фактора некрозу пухлин альфа , спосіб полегшення шкідливих ефектів надлишкового продукування фактора некрозу пухлин альфа та спосіб лікування запального стану або захворювання, пов'язаного з фактором некрозу пухлин. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6184217B1 (2) |
| EP (1) | EP0912184B1 (2) |
| JP (2) | JP2000514420A (2) |
| CN (1) | CN1108799C (2) |
| AT (1) | ATE224718T1 (2) |
| AU (1) | AU721942B2 (2) |
| BR (1) | BR9710693A (2) |
| DE (1) | DE69715862T2 (2) |
| DK (1) | DK0912184T3 (2) |
| ES (1) | ES2184106T3 (2) |
| NO (1) | NO317335B1 (2) |
| NZ (1) | NZ333441A (2) |
| PT (1) | PT912184E (2) |
| RU (1) | RU2183959C2 (2) |
| UA (1) | UA65542C2 (2) |
| WO (1) | WO1997049406A1 (2) |
Families Citing this family (25)
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| US6127401A (en) * | 1998-06-05 | 2000-10-03 | Cephalon, Inc. | Bridged indenopyrrolocarbazoles |
| US6200968B1 (en) * | 1998-08-06 | 2001-03-13 | Cephalon, Inc. | Particle-forming compositions containing fused pyrrolocarbazoles |
| WO2000018407A1 (en) | 1998-09-25 | 2000-04-06 | Cephalon, Inc. | Methods for preventing/treating damage to sensory hair cells and cochlear neurons |
| CA2347519A1 (en) | 1998-10-13 | 2000-04-20 | Kyowa Hakko Kogyo Co., Ltd. | An agent for treating ophthalmopathy |
| JP2000290184A (ja) * | 1999-04-01 | 2000-10-17 | Kyowa Hakko Kogyo Co Ltd | 経鼻投与製剤 |
| WO2001051046A1 (en) * | 2000-01-14 | 2001-07-19 | University Of Virginia Patent Foundation | Airway alkalinization as therapy for airway diseases |
| WO2001085151A2 (en) * | 2000-05-08 | 2001-11-15 | Psoriasis Research Institute | Chimeric animal model and treatment of psoriasis |
| US7129250B2 (en) | 2000-05-19 | 2006-10-31 | Aegera Therapeutics Inc. | Neuroprotective and anti-proliferative compounds |
| US7018999B2 (en) | 2001-05-16 | 2006-03-28 | Cephalon, Inc. | Methods for the treatment and prevention of pain |
| NZ540879A (en) * | 2002-12-23 | 2008-08-29 | Rinat Neuroscience Corp | Methods for treating taxol-induced sensory neuropathy |
| WO2004085648A2 (en) | 2003-03-19 | 2004-10-07 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
| EP1620127A4 (en) * | 2003-03-20 | 2007-04-04 | Rinat Neuroscience Corp | METHOD FOR TREATING TAXOL-INDUCED ANTI-FERROUS DISORDER |
| TWI324604B (en) * | 2003-06-18 | 2010-05-11 | Novartis Ag | New use of staurosporine derivatives |
| WO2005007144A2 (en) * | 2003-07-14 | 2005-01-27 | Decode Genetics Ehf | Method of diagnosis and treatment for asthma based on haplotype association |
| US20060014165A1 (en) * | 2003-07-14 | 2006-01-19 | Decode Genetics Ehf. | Methods of diagnosis and treatment for asthma and other respiratory diseases based on haplotype association |
| US20060210553A1 (en) * | 2003-07-23 | 2006-09-21 | Creabilis Therapeutics S.R.L. | Topical use of tyrosine kinase inhibitors of microbial origin to prevent and treat skin disorders characterised by excesssive cell proliferation |
| AU2005217024B2 (en) | 2004-02-27 | 2011-03-24 | Cephalon, Inc. | Crystalline forms of a pharmaceutical compound |
| PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| AR054260A1 (es) * | 2005-04-26 | 2007-06-13 | Rinat Neuroscience Corp | Metodos de tratamiento de enfermedades de la neurona motora inferior y composiciones utilizadas en los mismos |
| SI1904104T1 (sl) | 2005-07-08 | 2013-12-31 | Biogen Idec Ma Inc. | Protitelesa SP35 in njihova uporaba |
| JP2009544703A (ja) * | 2006-07-24 | 2009-12-17 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｓｐ３５またはＴｒｋＡアンタゴニストの投与により髄鞘形成、ニューロンの生存および希乏突起膠細胞の分化を促進するための方法 |
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| CN104470541A (zh) | 2012-05-14 | 2015-03-25 | 比奥根艾迪克Ma公司 | 用于治疗涉及运动神经元的疾患的lingo-2拮抗剂 |
| JP2018504400A (ja) | 2015-01-08 | 2018-02-15 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | Ｌｉｎｇｏ‐１拮抗薬及び脱髄障害の治療のための使用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS6041489A (ja) * | 1983-08-12 | 1985-03-05 | Kyowa Hakko Kogyo Co Ltd | 新規生理活性物質ｋ―２５２ |
| US4554402A (en) | 1983-12-23 | 1985-11-19 | Aluminum Company Of America | Vibration damper for overhead conductor |
| JPS62120388A (ja) | 1985-11-19 | 1987-06-01 | Meiji Seika Kaisha Ltd | Ｓｆ−２３７０物質ハロゲン化誘導体とその製造法 |
| JPS62155284A (ja) | 1985-12-27 | 1987-07-10 | Kyowa Hakko Kogyo Co Ltd | 生理活性物質ｋ−２５２の誘導体 |
| JPS62155285A (ja) | 1985-12-27 | 1987-07-10 | Kyowa Hakko Kogyo Co Ltd | 生理活性物質ｋ−２５２の誘導体 |
| JPS62220196A (ja) | 1986-03-20 | 1987-09-28 | Kyowa Hakko Kogyo Co Ltd | 新規物質ｕｃｎ―０１ |
| US4816450A (en) | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
| JPH0826036B2 (ja) | 1987-01-22 | 1996-03-13 | 協和醗酵工業株式会社 | 生理活性物質ｋ−２５２の誘導体 |
| US4735939A (en) | 1987-02-27 | 1988-04-05 | The Dow Chemical Company | Insecticidal activity of staurosporine |
| DE3752123T2 (de) | 1987-03-09 | 1998-05-14 | Kyowa Hakko Kogyo Kk | Derivate des physiologisch aktiven mittels k-252 |
| IL86632A0 (en) | 1987-06-15 | 1988-11-30 | Ciba Geigy Ag | Derivatives substituted at methyl-amino nitrogen |
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| JPH07113027B2 (ja) * | 1987-12-24 | 1995-12-06 | 協和醗酵工業株式会社 | Ｋ−２５２誘導体 |
| WO1989007105A1 (fr) | 1988-02-04 | 1989-08-10 | Kyowa Hakko Kogyo Co., Ltd. | Derives de staurosporine |
| DE3835842A1 (de) | 1988-10-21 | 1990-04-26 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| DE3924538A1 (de) | 1989-07-25 | 1991-01-31 | Goedecke Ag | Indolocarbazol und dessen verwendung |
| WO1991009034A1 (en) | 1989-12-14 | 1991-06-27 | Schering Corporation | Indolocarbazoles from saccharothrix aerocolonigenes subsp. copiosa subsp. nov. scc 1951 atcc 53856 |
| JPH0586068A (ja) | 1991-03-04 | 1993-04-06 | Rikagaku Kenkyusho | 新規抗生物質ｒｋ−１４０９、その製造法並びに抗腫瘍剤及び抗炎症剤 |
| WO1993008809A1 (en) | 1991-11-08 | 1993-05-13 | The University Of Southern California | Compositions containing k-252 compounds for potentiation of neurotrophin activity |
| JP2593021B2 (ja) | 1991-12-13 | 1997-03-19 | 伊藤ハム株式会社 | ウシ胚の性の識別方法 |
| RU2045575C1 (ru) * | 1992-01-29 | 1995-10-10 | Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Рекомбинатная плазмидная днк ppr - tgatg - hil - 1 beta - tsr, обеспечивающая синтез рекомбинантного интерлейкина-1 и штамм escherichia coli - продуцент рекомбинантного интерлейкина-1 бета человека |
| US6271242B1 (en) | 1992-02-10 | 2001-08-07 | Bristol-Myers Squibb Co. | Method for treating cancer using a tyrosine protein kinase inhibitor |
| JPH05247055A (ja) | 1992-03-03 | 1993-09-24 | Meiji Seika Kaisha Ltd | スタウロスポリン誘導体及びそれを含有する抗腫瘍効果増強剤 |
| JPH0673063A (ja) | 1992-06-22 | 1994-03-15 | Kyowa Hakko Kogyo Co Ltd | Ｕｃｎ−０１誘導体 |
| DE69326388T2 (de) | 1992-06-22 | 1999-12-30 | Kyowa Hakko Kogyo Co., Ltd. | Verfahren zur Herstellung von Staurosporin-Derivaten |
| US5461146A (en) * | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
| US5621100A (en) | 1992-07-24 | 1997-04-15 | Cephalon, Inc. | K-252a derivatives for treatment of neurological disorders |
| GB9215921D0 (en) * | 1992-07-27 | 1992-09-09 | Wellcome Found | Anti-inflammatory compounds |
| DE69409641T2 (de) | 1993-05-28 | 1998-11-26 | Cephalon, Inc., West Chester, Pa. | Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen |
| AU7000094A (en) | 1993-06-17 | 1995-01-17 | Ciba-Geigy Ag | Indolocarbazole compound useful as proteinkinase c inhibitor |
| AU1911095A (en) | 1994-02-18 | 1995-09-04 | Cephalon, Inc. | Aqueous indolocarbazole solutions |
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1997
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- 1997-06-24 US US08/881,679 patent/US6184217B1/en not_active Expired - Lifetime
- 1997-06-24 RU RU99101117/14A patent/RU2183959C2/ru active
- 1997-06-24 EP EP97930203A patent/EP0912184B1/en not_active Expired - Lifetime
- 1997-06-24 ES ES97930203T patent/ES2184106T3/es not_active Expired - Lifetime
- 1997-06-24 AT AT97930203T patent/ATE224718T1/de active
- 1997-06-24 WO PCT/US1997/010898 patent/WO1997049406A1/en not_active Ceased
- 1997-06-24 NZ NZ333441A patent/NZ333441A/xx not_active IP Right Cessation
- 1997-06-24 BR BR9710693-3A patent/BR9710693A/pt not_active IP Right Cessation
- 1997-06-24 UA UA99010342A patent/UA65542C2/uk unknown
- 1997-06-24 DK DK97930203T patent/DK0912184T3/da active
- 1997-06-24 AU AU34090/97A patent/AU721942B2/en not_active Expired
- 1997-06-24 CN CN97197341A patent/CN1108799C/zh not_active Expired - Lifetime
- 1997-06-24 JP JP10503444A patent/JP2000514420A/ja active Pending
- 1997-06-24 DE DE69715862T patent/DE69715862T2/de not_active Expired - Lifetime
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1998
- 1998-12-23 NO NO19986111A patent/NO317335B1/no not_active IP Right Cessation
-
2008
- 2008-03-04 JP JP2008053174A patent/JP4767982B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO986111L (no) | 1999-02-23 |
| NZ333441A (en) | 1999-05-28 |
| JP2000514420A (ja) | 2000-10-31 |
| ATE224718T1 (de) | 2002-10-15 |
| EP0912184B1 (en) | 2002-09-25 |
| NO317335B1 (no) | 2004-10-11 |
| PT912184E (pt) | 2002-12-31 |
| US6184217B1 (en) | 2001-02-06 |
| ES2184106T3 (es) | 2003-04-01 |
| AU721942B2 (en) | 2000-07-20 |
| AU3409097A (en) | 1998-01-14 |
| NO986111D0 (no) | 1998-12-23 |
| EP0912184A1 (en) | 1999-05-06 |
| RU2183959C2 (ru) | 2002-06-27 |
| JP4767982B2 (ja) | 2011-09-07 |
| HK1018745A1 (en) | 2000-01-07 |
| DK0912184T3 (da) | 2002-11-25 |
| WO1997049406A1 (en) | 1997-12-31 |
| BR9710693A (pt) | 2000-01-11 |
| DE69715862D1 (de) | 2002-10-31 |
| JP2008189676A (ja) | 2008-08-21 |
| DE69715862T2 (de) | 2003-04-10 |
| CN1108799C (zh) | 2003-05-21 |
| CN1228024A (zh) | 1999-09-08 |
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