UA64797C2 - Інгібітори фарнезил білок трансферази як засіб для лікування артропатії - Google Patents
Інгібітори фарнезил білок трансферази як засіб для лікування артропатії Download PDFInfo
- Publication number
- UA64797C2 UA64797C2 UA2000127574A UA00127574A UA64797C2 UA 64797 C2 UA64797 C2 UA 64797C2 UA 2000127574 A UA2000127574 A UA 2000127574A UA 00127574 A UA00127574 A UA 00127574A UA 64797 C2 UA64797 C2 UA 64797C2
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- UA
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- Prior art keywords
- alkyl
- alkyloxy
- formula
- methyl
- amino
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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| EP98202258 | 1998-07-06 | ||
| PCT/EP1999/004546 WO2000001386A1 (fr) | 1998-07-06 | 1999-06-30 | Inhibiteurs de farnesyl proteine transferase pour le traitement des arthropathies |
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| UA64797C2 true UA64797C2 (uk) | 2004-03-15 |
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| CN (1) | CN1170538C (fr) |
| AP (1) | AP1597A (fr) |
| AT (1) | ATE253914T1 (fr) |
| AU (1) | AU762470B2 (fr) |
| BG (1) | BG64939B1 (fr) |
| BR (1) | BR9911869A (fr) |
| CA (1) | CA2337800C (fr) |
| CZ (1) | CZ302269B6 (fr) |
| DE (1) | DE69912790T2 (fr) |
| DK (1) | DK1094815T3 (fr) |
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| ES (1) | ES2212580T3 (fr) |
| HK (1) | HK1034450A1 (fr) |
| HR (1) | HRP20000904A2 (fr) |
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| ID (1) | ID27199A (fr) |
| IL (2) | IL140720A0 (fr) |
| MY (1) | MY122189A (fr) |
| NO (1) | NO318338B1 (fr) |
| NZ (1) | NZ509647A (fr) |
| PL (1) | PL193296B1 (fr) |
| PT (1) | PT1094815E (fr) |
| SI (1) | SI1094815T1 (fr) |
| SK (1) | SK285231B6 (fr) |
| TR (1) | TR200003882T2 (fr) |
| TW (1) | TW557212B (fr) |
| UA (1) | UA64797C2 (fr) |
| WO (1) | WO2000001386A1 (fr) |
| ZA (1) | ZA200100152B (fr) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| BR9911869A (pt) | 1998-07-06 | 2001-03-27 | Janssen Pharmaceutica Nv | Inibidores da transferase da proteìna farnesil para o tratamento das artropatias |
| DE60008206T2 (de) | 1999-11-30 | 2004-12-02 | Pfizer Products Inc., Groton | Chinolinderivate verwendbar zur Hemmung der Farnesyl-Protein Transferase |
| JO2361B1 (en) | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Enaniumer 1,2-anylated quinoline inhibitor for the transporter - farnesyl |
| AU2001293829A1 (en) | 2000-09-25 | 2002-04-02 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 6-((substituted phenyl)methyl)-quinoline and quinazoline derivatives |
| ATE409189T1 (de) | 2000-09-25 | 2008-10-15 | Janssen Pharmaceutica Nv | Farnesyl transferase-hemmende 6- heterocyclylmethyl-chinolin und chinazol-derivate |
| US7067531B2 (en) | 2000-09-25 | 2006-06-27 | Angibaud Patrick Rene | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinolinone derivatives |
| WO2002024682A1 (fr) | 2000-09-25 | 2002-03-28 | Janssen Pharmaceutica N.V. | Derives de quinoline et de quinazoline inhibant la farnesyl transferase comme inhibiteurs de farnesyl transferase |
| AU2002214056A1 (en) | 2000-11-21 | 2002-06-03 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting benzoheterocyclic derivatives |
| US7129356B2 (en) | 2000-12-27 | 2006-10-31 | Janssen Pharmaceutica N.V. | Farnesyl transferase inhibiting 4-substituted quinoline and quinazoline derivatives |
| DE60119383T2 (de) * | 2000-12-27 | 2007-04-19 | Janssen Pharmaceutica N.V. | Farnesyltransferasehemmende 4-heterocyclylchinolin- und chinazolinderivate |
| WO2002098370A2 (fr) * | 2001-03-02 | 2002-12-12 | Medimmune, Inc. | Methodes d'administration/dosage d'antagonistes de cd2 pour la prevention et le traitement des maladies auto-immunes ou inflammatoires |
| US6706699B2 (en) * | 2001-06-21 | 2004-03-16 | Ariad Pharmaceuticals, Inc. | Quinolines and uses thereof |
| US6713462B2 (en) | 2001-06-21 | 2004-03-30 | Ariad Pharmaceuticals, Inc. | Quinolinones and uses thereof |
| ES2323265T3 (es) | 2001-12-19 | 2009-07-10 | Janssen Pharmaceutica Nv | Derivados de quinolina condensados en 1,8 sustituidos con triazoles unidos por el carbono como inhibidores de la farnesil-transferasa. |
| AU2003223970B2 (en) | 2002-03-22 | 2008-03-06 | Janssen Pharmaceutica N.V. | Benzylimidazolyl substituted 2-quinoline and quinazoline derivatives for use as farnesyl transferase inhibitors |
| CA2481480C (fr) | 2002-04-15 | 2011-04-12 | Janssen Pharmaceutica N.V. | Derives de quinazoline tricylique inhibant la farnesyl transferase substitues avec des imidazoles ou des triazoles a liaison carbone |
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