UA6340A1 - Спосіб одержання заміщених діазабіціклоалкілхінолон карбонових кислот мостиковим зв'язком або їх фармацевтично прийнятних адитивний солей - Google Patents
Спосіб одержання заміщених діазабіціклоалкілхінолон карбонових кислот мостиковим зв'язком або їх фармацевтично прийнятних адитивний солейInfo
- Publication number
- UA6340A1 UA6340A1 UA4028142A UA4028142A UA6340A1 UA 6340 A1 UA6340 A1 UA 6340A1 UA 4028142 A UA4028142 A UA 4028142A UA 4028142 A UA4028142 A UA 4028142A UA 6340 A1 UA6340 A1 UA 6340A1
- Authority
- UA
- Ukraine
- Prior art keywords
- cross
- diazabicycloalkylquinolon
- carboxylic acids
- linking bond
- pharmaceutically acceptable
- Prior art date
Links
- 238000004132 cross linking Methods 0.000 title abstract 3
- 150000001735 carboxylic acids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000654 additive Substances 0.000 title 1
- 230000000996 additive effect Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000250 methylamino group Chemical group [H]N(*)C([H])([H])[H] 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77747185A | 1985-09-18 | 1985-09-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA6340A1 true UA6340A1 (uk) | 1994-12-29 |
Family
ID=25110350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA4028142A UA6340A1 (uk) | 1985-09-18 | 1986-09-17 | Спосіб одержання заміщених діазабіціклоалкілхінолон карбонових кислот мостиковим зв'язком або їх фармацевтично прийнятних адитивний солей |
Country Status (42)
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN166416B (OSRAM) * | 1985-09-18 | 1990-05-05 | Pfizer | |
| DE3601567A1 (de) * | 1986-01-21 | 1987-07-23 | Bayer Ag | 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate |
| EP0251308B1 (de) * | 1986-07-04 | 1990-11-22 | Chemie Linz Gesellschaft m.b.H. | 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| US4965273A (en) * | 1986-10-08 | 1990-10-23 | Bristol-Myers Company | Certain 1-tertiary-butyl-naphthyridone carboxylic acid derivatives anti-bacterial agents |
| WO1989000158A1 (en) * | 1987-07-02 | 1989-01-12 | Pfizer Inc. | Bridged-diazabicycloalkyl quinolone carboxylic acids and esters |
| US4992546A (en) * | 1987-07-31 | 1991-02-12 | Warner-Lambert Company | Process for preparing 6,8-diazabicyclo[3.2.2]nonane derivatives |
| US4968799A (en) * | 1987-07-31 | 1990-11-06 | Warner-Lambert Company | Antibacterial agents |
| US4923879A (en) * | 1987-07-31 | 1990-05-08 | Warner-Lambert Company | 1,8-Naphthyridines and their use as antibacterial agents |
| US4933335A (en) * | 1987-08-07 | 1990-06-12 | Warner-Lambert Company | Quinolones as antibacterial agents |
| WO1989005643A1 (en) * | 1987-12-18 | 1989-06-29 | Pfizer Inc. | Heterocyclic-substituted quinoline-carboxylic acids |
| DE3902079A1 (de) * | 1988-04-15 | 1989-10-26 | Bayer Ag | I.m. injektionsformen von gyrase-inhibitoren |
| US5147873A (en) * | 1988-08-23 | 1992-09-15 | Pfizer Inc. | Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters |
| WO1990002123A1 (en) * | 1988-08-23 | 1990-03-08 | Pfizer Inc. | Amino-substituted bridged azabicyclic quinolone carboxylic acids and esters |
| US4895943A (en) * | 1988-10-25 | 1990-01-23 | Pfizer Inc. | Preparation of 1,4-diazabicyclo(3.2.2)nonane |
| US5036153A (en) * | 1989-05-11 | 1991-07-30 | Braish Tamim F | Preparation of 2,5-diazabicyclo[2.2.1]heptanes and intermediates |
| US5214051A (en) * | 1989-08-01 | 1993-05-25 | Pfizer Inc. | Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed |
| US5157125A (en) * | 1989-09-25 | 1992-10-20 | Pfizer Inc. | Optically active 2-alkyl-2,5-diazabicyclo[2.2.1]heptanes |
| US5095121A (en) * | 1989-09-25 | 1992-03-10 | Pfizer Inc | Process for optically active 2-alkyl-2,5-diazabicyclo(2.2.1)heptanes |
| US5013839A (en) * | 1989-09-25 | 1991-05-07 | Pfizer Inc. | Process for optically active 2-alkyl-2,5-diazabicyclo(2.2.1) heptanes |
| WO1991004972A1 (en) * | 1989-10-06 | 1991-04-18 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
| US5385913A (en) * | 1989-10-06 | 1995-01-31 | Pfizer Inc. | 1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents |
| US4992449A (en) * | 1990-02-01 | 1991-02-12 | American Cyanamid Company | 7-(substituted)cycloalkylamino-1-(substituted)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids |
| US5580872A (en) * | 1990-05-02 | 1996-12-03 | Abbott Laboratories | Quinolizinone type compounds |
| EP0573522B1 (en) * | 1991-03-01 | 1994-12-14 | Pfizer Inc. | 1-azabicyclo[3.2.2]nonan-3-amine derivatives |
| US5235054A (en) * | 1992-07-15 | 1993-08-10 | Pfizer Inc. | 3-carboxaldehyde substituted quinolines and naphthyridines |
| GB2291421A (en) * | 1994-07-16 | 1996-01-24 | Pfizer | A process for preparing a quinoline carboxylic acid |
| ES2092963B1 (es) * | 1995-04-12 | 1997-12-16 | Sint Quimica Sa | Procedimiento para la preparacion del acido 1-ciclopropil-6-fluoro-1, 4-dihidro-7-(1s,4s)-5-metil-2,5-diazabiciclo(2.2.1) hept-2-il)-4-oxo-3-quinolincarboxilico y sus sales. |
| US5929086A (en) * | 1996-05-10 | 1999-07-27 | Pharmacia & Upjohn Company | Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases |
| US6056436A (en) * | 1997-02-20 | 2000-05-02 | University Of Maryland | Simultaneous measurement of temperature and strain using optical sensors |
| US6114531A (en) * | 1998-07-28 | 2000-09-05 | Pfizer Inc. | Process for preparing quinolone and naphthyridone carboxylic acids |
| EP1177196B1 (en) | 1999-05-04 | 2004-03-10 | Neurosearch A/S | Heteroaryl diazabicycloalkanes, their preparation and use |
| FR2809732B1 (fr) * | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE |
| FR2809731B1 (fr) * | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique |
| FR2809730B1 (fr) * | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique |
| DE60202667T2 (de) * | 2001-03-02 | 2005-06-16 | Neurosearch A/S | Neue 2,5-diazabicyclo [2.2.1] heptanderivate |
| WO2004024729A1 (en) * | 2002-09-10 | 2004-03-25 | Pfizer Products Inc. | Diazabicyclic compounds useful in the treatment of cns and other disorders |
| PL210065B1 (pl) | 2002-09-25 | 2011-11-30 | Memory Pharm Corp | Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków |
| DE10312346A1 (de) * | 2003-03-20 | 2004-09-30 | Bayer Healthcare Ag | Kontrolliertes Freisetzungssystem |
| DE10351448A1 (de) | 2003-11-04 | 2005-06-09 | Bayer Healthcare Ag | Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften |
| EP1697378B1 (en) | 2003-12-22 | 2007-11-21 | Memory Pharmaceuticals Corporation | Indoles, 1h-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, and preparation and uses thereof |
| EP1735306A2 (en) | 2004-03-25 | 2006-12-27 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
| EP1742944B1 (en) * | 2004-04-22 | 2010-11-10 | Memory Pharmaceuticals Corporation | Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof |
| KR20070015607A (ko) * | 2004-05-07 | 2007-02-05 | 메모리 파마슈티칼스 코포레이션 | 1ｈ-인다졸, 벤조티아졸, 1,2-벤조이속사졸,1,2-벤조이소티아졸, 및 크로몬 및 그의 제조법 및 용도 |
| DE102005055385A1 (de) * | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
| ATE455776T1 (de) * | 2004-12-22 | 2010-02-15 | Memory Pharm Corp | Nikotinische alpha-7-rezeptorliganden gegen erkrankungen des zns |
| US8106066B2 (en) | 2005-09-23 | 2012-01-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
| US7700596B2 (en) | 2006-02-10 | 2010-04-20 | Neurosearch A/S | 3,9-diazabicyclo[3.3.1]nonane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| CA2641685A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3-heteroaryl-3,9-diazabicyclo[3.3.1]nonane derivatives as nicotinic acetylcholine receptor agonists |
| WO2007090887A1 (en) | 2006-02-10 | 2007-08-16 | Neurosearch A/S | 3, 9-diazabicyclo [3.3. 1]nonane derivatives and their use as monoamine?neurotransmitter re-uptake inhibitors |
| DE102006010643A1 (de) | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
| DE102006010642A1 (de) * | 2006-03-08 | 2007-09-27 | Bayer Healthcare Aktiengesellschaft | Arzneimittelformulierungen, enthaltend Fluorchinolone |
| DE102007026550A1 (de) | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
| DE102007055341A1 (de) * | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| WO2009111680A1 (en) * | 2008-03-07 | 2009-09-11 | Smithline Beecham Corporation | Trpv4 antagonists |
| JP5502889B2 (ja) * | 2009-03-11 | 2014-05-28 | 杏林製薬株式会社 | ｇｓｋ−３阻害剤としての７−シクロアルキルアミノキノロン |
| CA2814082A1 (en) | 2010-10-12 | 2012-04-19 | Bayer Intellectual Property Gmbh | Non-starch based soft chewables |
| JP6393274B2 (ja) | 2012-12-19 | 2018-09-19 | バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ａｎｉｍａｌ Ｈｅａｌｔｈ Ｇｍｂｈ | 改良された許容性および良好な保存安定性を有する錠剤 |
| MD4291C1 (ro) * | 2013-12-27 | 2015-02-28 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Preparat medicamentos pentru tratamentul otitelor |
| EP3975994A4 (en) | 2019-05-24 | 2023-06-14 | Piedmont Animal Health Inc. | LONG-ACTING INJECTABLE FORMULATIONS AND THEIR USE |
| AU2020341552A1 (en) * | 2019-09-06 | 2022-04-21 | Elanco Us Inc. | Palatable granular veterinary compositions |
| CN115368369A (zh) * | 2022-08-16 | 2022-11-22 | 浙江国邦药业有限公司 | 一种甲磺酸达氟沙星脱甲基杂质的合成方法 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
| US4292317A (en) * | 1977-09-20 | 1981-09-29 | Laboratorie Roger Bellon | 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them |
| JPS54112876A (en) * | 1978-02-20 | 1979-09-04 | Sumitomo Chem Co Ltd | Preparation of 1-substituted-1,4-dihydro-4-oxo-3-quinoline carboxylic acid derivatives |
| JPS5845426B2 (ja) * | 1978-09-29 | 1983-10-08 | 杏林製薬株式会社 | 置換キノリンカルボン酸誘導体 |
| JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
| JPS5823381A (ja) * | 1981-08-05 | 1983-02-12 | Nec Corp | 磁気バブル検出装置 |
| JPS5823382A (ja) * | 1981-08-05 | 1983-02-12 | Nec Corp | コンテイギユアス・デイスク・バブル検出・消去器 |
| JPS58204193A (ja) * | 1982-01-14 | 1983-11-28 | Kobe Steel Ltd | 表面処理鋼板 |
| US4499091A (en) * | 1982-03-31 | 1985-02-12 | Sterling Drug Inc. | 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents |
| EP0090424B1 (en) * | 1982-03-31 | 1986-05-28 | Sterling Drug Inc. | New quinolone compounds and preparation thereof |
| JPS58204194A (ja) * | 1982-05-21 | 1983-11-28 | Hitachi Ltd | 電気ニツケルメツキ方法 |
| JPS58219293A (ja) * | 1982-06-15 | 1983-12-20 | Chiyoda Chem Eng & Constr Co Ltd | 重質油の水素化分解方法 |
| US4665079A (en) * | 1984-02-17 | 1987-05-12 | Warner-Lambert Company | Antibacterial agents |
| IE55898B1 (en) * | 1982-09-09 | 1991-02-14 | Warner Lambert Co | Antibacterial agents |
| JPS59137481A (ja) * | 1983-01-26 | 1984-08-07 | Hokuriku Seiyaku Co Ltd | ７−ジアザビシクロアルカン置換−４−オキソ−１，４−ジヒドロキノリン−３−カルボン酸誘導体 |
| NZ208470A (en) * | 1983-07-18 | 1988-06-30 | Abbott Lab | 6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such |
| US4730000A (en) * | 1984-04-09 | 1988-03-08 | Abbott Laboratories | Quinoline antibacterial compounds |
| US4571396A (en) * | 1984-04-16 | 1986-02-18 | Warner-Lambert Company | Antibacterial agents |
| DE3576335D1 (de) * | 1984-12-14 | 1990-04-12 | Daiichi Seiyaku Co | Chinolincarbonsaeure-derivate. |
| IL77846A (en) * | 1985-03-25 | 1989-08-15 | Warner Lambert Co | Process for the preparation of 7-amino-quinolin-4-oxy-3-carboxylic acid derivatives |
| US4578473A (en) * | 1985-04-15 | 1986-03-25 | Warner-Lambert Company | Process for quinoline-3-carboxylic acid antibacterial agents |
| US4684648A (en) * | 1985-05-10 | 1987-08-04 | Otsuka Pharmaceutical Company Limited | Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof |
| IN166416B (OSRAM) * | 1985-09-18 | 1990-05-05 | Pfizer | |
| US4772706A (en) * | 1986-01-13 | 1988-09-20 | Warner-Lambert Company | Process for quinoline-3-carboxylic acid antibacterial agents |
| US4840956A (en) * | 1986-02-18 | 1989-06-20 | Warner-Lambert Company | Novel disubstituted-7-pyrrolidinoquinoline antibacterial agents |
| DE3721745A1 (de) * | 1986-07-04 | 1988-01-14 | Lentia Gmbh | Bicyclisch substituierte chinoloncarbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| EP0251308B1 (de) * | 1986-07-04 | 1990-11-22 | Chemie Linz Gesellschaft m.b.H. | 4-Chinolon-3-carbonsäurederivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| DE3641312A1 (de) * | 1986-12-03 | 1988-06-09 | Bayer Ag | Verfahren zur herstellung von chinolincarbonsaeuren |
| US4923879A (en) * | 1987-07-31 | 1990-05-08 | Warner-Lambert Company | 1,8-Naphthyridines and their use as antibacterial agents |
| US4851418A (en) * | 1987-08-21 | 1989-07-25 | Warner-Lambert Company | Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent |
-
1986
- 1986-08-18 IN IN740/DEL/86A patent/IN166416B/en unknown
- 1986-08-19 US US06/898,458 patent/US4775668A/en not_active Expired - Lifetime
- 1986-08-19 US US06/898,473 patent/US4861779A/en not_active Expired - Lifetime
- 1986-08-28 MW MW58/86A patent/MW5886A1/xx unknown
- 1986-09-03 ZM ZM85/86A patent/ZM8586A1/xx unknown
- 1986-09-12 DE DE1996175019 patent/DE19675019I2/de active Active
- 1986-09-12 EP EP86307045A patent/EP0215650B1/en not_active Expired - Lifetime
- 1986-09-12 AT AT86307045T patent/ATE72245T1/de active
- 1986-09-12 DE DE8686307045T patent/DE3683711D1/de not_active Expired - Lifetime
- 1986-09-15 IL IL80033A patent/IL80033A/xx not_active IP Right Cessation
- 1986-09-15 EG EG580/86A patent/EG18184A/xx active
- 1986-09-16 PL PL1986261410A patent/PL149987B1/pl unknown
- 1986-09-16 PT PT83388A patent/PT83388B/pt unknown
- 1986-09-16 SK SK6678-86A patent/SK278605B6/sk unknown
- 1986-09-16 ES ES8601935A patent/ES2001428A6/es not_active Expired
- 1986-09-16 CZ CS866678A patent/CZ277825B6/cs not_active IP Right Cessation
- 1986-09-16 GR GR862363A patent/GR862363B/el unknown
- 1986-09-16 CA CA000518238A patent/CA1340734C/en not_active Expired - Lifetime
- 1986-09-17 UA UA4028142A patent/UA6340A1/uk unknown
- 1986-09-17 ZW ZW193/86A patent/ZW19386A1/xx unknown
- 1986-09-17 DK DK445886A patent/DK171276B1/da not_active IP Right Cessation
- 1986-09-17 MA MA20998A patent/MA20770A1/fr unknown
- 1986-09-17 IE IE247986A patent/IE58966B1/en not_active IP Right Cessation
- 1986-09-17 NO NO863718A patent/NO170335C/no not_active IP Right Cessation
- 1986-09-17 YU YU1617/86A patent/YU45024B/xx unknown
- 1986-09-17 KR KR1019860007855A patent/KR870000961B1/ko not_active Expired
- 1986-09-17 AU AU62768/86A patent/AU576302B2/en not_active Expired
- 1986-09-17 CN CN86106385A patent/CN1014789B/zh not_active Expired
- 1986-09-17 NZ NZ217614A patent/NZ217614A/xx unknown
- 1986-09-17 OA OA58953A patent/OA08410A/xx unknown
- 1986-09-17 MX MX003751A patent/MX173358B/es unknown
- 1986-09-17 DD DD86294486A patent/DD259190A5/de unknown
- 1986-09-17 HU HU863976A patent/HU200462B/hu unknown
- 1986-09-17 SU SU864028142A patent/SU1482531A3/ru active
- 1986-09-17 ZA ZA867063A patent/ZA867063B/xx unknown
- 1986-09-17 FI FI863756A patent/FI87565C/fi not_active IP Right Cessation
- 1986-09-18 JP JP61220819A patent/JPH0798819B2/ja not_active Expired - Lifetime
- 1986-09-18 BG BG076465A patent/BG49275A3/xx unknown
- 1986-09-18 PH PH34266A patent/PH24048A/en unknown
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1987
- 1987-08-25 MY MYPI87001447A patent/MY102518A/en unknown
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1988
- 1988-02-16 US US07/157,182 patent/US5091383A/en not_active Expired - Fee Related
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1989
- 1989-07-11 PH PH38922A patent/PH25338A/en unknown
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1992
- 1992-03-17 BG BG096080A patent/BG61091B2/bg unknown
-
1994
- 1994-02-22 SG SG28094A patent/SG28094G/en unknown
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1995
- 1995-08-24 HK HK132795A patent/HK132795A/en not_active IP Right Cessation
- 1995-10-20 CY CY177495A patent/CY1774A/xx unknown
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1999
- 1999-02-24 LU LU90356C patent/LU90356I2/xx unknown
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